As a leading 4-[4-({[4-Chloro-3-(Trifluoromethyl)Phenyl]Carbamoyl}Amino)Phenoxy]-N-Methylpyridine-2-Carboxamide 4-Methylbenzenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4- [4- ({[4-chloro-3- (trifluoromethyl) phenyl] carbamyl} amino) phenoxy] -N-methylpyridine-2-formamide 4-methylbenzenesulfonate?
This organic compound has a complex structure, a long name and many professional chemical group expressions, so you can sort out its chemical structure in classical Chinese form.
Looking at this compound, it is based on a benzene ring, which is connected with various groups. At position 4, there is a complex substituted structure. Looking at the inner layer first, there is a group containing "oxygen-3 - (trifluoromethyl) phenoxy", which is connected to the acetyl group, which is then connected to the phenoxy group, which is in turn connected to the main structure. At the same time, there is a part of "N-methyl-2-acetamido" and a fragment of "4-phenylmethylsulfonamide".
Its overall structure is like a carefully constructed chemical building. The benzene ring is like the cornerstone of the building, and the substituent groups are like pavilions of the building, built according to specific rules. The "oxygen-3 - (trifluoromethyl) phenoxy acetyl phenoxy" part is like the eaves of a pavilion, with a unique shape and exquisite structure; the "N-methyl-2-acetamide" and "4-methylbenzenesulfonamide" fragments are like the wing of a pavilion, which are closely connected to the main structure, and each part is interdependent to form this complex chemical structure. This structure gives the compound unique chemical properties and potential application value.
What are the main uses of 4- [4- ({[4-chloro-3- (trifluoromethyl) phenyl] carbamyl} amino) phenoxy] -N-methylpyridine-2-formamide 4-methylbenzene sulfonate?
4- [4- ({[4-hydroxy- 3- (triethyl) benzyl] oxymethylene} oxymethylene) ] -N-methylpiperidine-2-methylenone + 4-methylbenzylsulfinamide This compound has important uses in the field of medicinal chemistry. In drug development, it can be used as a key intermediate to construct complex molecular structures with specific pharmacological activities. Its unique chemical structure confers potential interaction with biological targets, or can be used to develop novel therapeutic drugs, such as targeted therapeutic drugs for certain specific diseases.
In organic synthetic chemistry, it is an important building block for the design and synthesis of new organic compounds, which helps scientists to explore new reaction paths and chemical transformations, providing the possibility for the synthesis of organic materials with special functions or structures.
In addition, the study of this compound can also deepen our understanding of the relationship between the structure and activity of organic molecules, and provide experimental basis for the theoretical development of drug design and organic synthesis, thereby promoting further innovation and development in related fields.
What is the safety of 4- [4- ({[4-chloro-3- (trifluoromethyl) phenyl] carbamyl} amino) phenoxy] -N-methylpyridine-2-formamide 4-methylbenzene sulfonate?
The structure of this compound is complex, and its safety needs to be considered from many aspects.
Looking at its structure, it contains a variety of functional groups. Halogenated parts, halogen atom activity or affect its chemical reactivity and biological activity, some halogenated hydrocarbons are toxic, absorbed through the skin, inhaled or ingested by mistake, or interfere with normal biochemical reactions in organisms.
Ether bonds are relatively stable, but under specific conditions such as strong acid, high temperature, or cracking to produce harmful small molecules.
Amino groups are basic and can react with acids to form salts, which affects the physical and chemical properties of compounds, and some amine compounds are irritating to organisms, and may damage the respiratory tract and skin mucosa at high concentrations.
The ester group is hydrolyzed in vivo or by esterase, and the product may have biological activity. Different ester hydrolysates are different, or have toxic or biological activity effects.
In addition, the safety of the compound is also related to its purity, impurities or high toxicity. Its stability is also critical, and it may degrade into harmful substances when unstable.
To accurately evaluate the safety of this compound, in-depth experimental studies are needed, covering acute toxicity, chronic toxicity, genotoxicity, reproductive toxicity, etc., combined with experimental data, to reach a reliable conclusion.
What are the synthesis methods of 4- [4- ({[4-chloro-3- (trifluoromethyl) phenyl] carbamyl} amino) phenoxy] -N-methylpyridine-2-formamide 4-methylbenzene sulfonate?
To prepare 4- [4- ({[4-alkane-3- (triethyl) benzyl] aminoethyl} amino) benzyloxy] -N-methylpiperidine-2-acetamide and 4-methylbenzyl thioanhydride, the following ancient method can be used:
4- [4- ({[4-alkane-3- (triethyl) benzyl] aminoethyl} amino) benzyloxy] -N-methylpiperidine-2-acetamide. Take an appropriate amount of 4-hydroxy-N-methylpiperidine-2-acetamide and dissolve it in a suitable organic solvent, such as dichloromethane or N, N-dimethylformamide. Under low temperature and stirring, slowly add alkali-containing reagents, such as potassium carbonate or sodium hydride, to alkalize the system. Then add 4- [4- ({[4-alkyl-3- (triethyl) benzyl] aminoethyl} amino) benzyl chloride dropwise, this chlorine must be prepared in advance by reacting the corresponding benzyl alcohol with a chlorination reagent such as sulfoxide chloride. After adding, heat up to a suitable temperature, continue to stir the reaction, and monitor the progress by thin-layer chromatography. When the reaction is complete, the reaction solution is poured into water, the product is extracted with an organic solvent, and the organic phases are combined. After drying with anhydrous sodium sulfate, the solvent is removed by distillation under reduced pressure. The residue is purified by column chromatography to obtain pure 4- [4- ({[4-alkane-3- (triethyl) benzyl] aminoethyl} amino) benzyloxy] -N-methylpiperidine-2-acetamide.
4-methylbenzyl thioanhydride is prepared. Take an appropriate amount of 4-methylbenzyl thiohydrin, use glacial acetic acid as a solvent, add an appropriate amount of oxidant, such as hydrogen peroxide or perbenzoic acid, and stir the reaction at room temperature or moderate heating conditions. The phenomenon is closely observed during the reaction. When the reaction is over, pour the reaction solution into ice water, precipitate out, filter and collect the precipitation, wash it with cold water several times, and dry it to obtain 4-methylbenzyl thioanhydride crude product, which is further purified by recrystallization method. A suitable solvent can be selected, such as ethanol-water mixed solvent, to obtain pure 4-methylbenzyl thioanhydride.
According to this two methods, the desired compound can be formed.
How competitive is 4- [4- ({[4-chloro-3- (trifluoromethyl) phenyl] carbamyl} amino) phenoxy] -N-methylpyridine-2-formamide 4-methylbenzene sulfonate in the market?
Looking at these four substances, they are 4 -% 5B4 -% 28% 7B% 5B4 - tritium - 3 - (trifluoromethyl) benzyl% 5D hydroxymethyl phosphorus% 7D hydroxymethyl% 29 benzyloxy% 5D - N - methyl, to its - 2 - methyl pyridine + 4 - methyl benzyl, phenolic anhydride, its competitiveness in the market can be discussed from the number.
First, the characteristics of these four substances are discussed. 4 -% 5B4 -% 28% 7B% 5B4 - tritium - 3 - (trifluoromethyl) benzyl% 5D hydroxymethyl phosphorus% 7D hydroxymethyl% 29 benzoxy% 5D - N - methyl, to its - 2 - methyl pyridine, exquisite structure, tritium, trifluoromethyl and other special groups are introduced, or make it have unique chemical activity and stability. And 4 - methyl benzyl, acid anhydride, also has its own reactivity and use.
From the perspective of the application field, if these four substances can be found in key fields such as medicine and materials, their competitiveness will be strong. In medicine, it can be used as an active ingredient to participate in drug synthesis. If it can show good pharmacological activity and low toxic and side effects, it will be favored by pharmaceutical companies. In the material industry, it can improve material properties, such as enhancing its weather resistance, mechanical properties, etc., and will win a place in the material market.
Furthermore, cost is also the key. If the production process of these four substances is simple and low-cost, and can be supplied to the market at a good price, it will surely attract more customers. If the preparation requires complex processes and high raw materials, the cost is high, and the competitiveness is vulnerable.
Technological innovation cannot be ignored. If we can continue to innovate in synthesis methods and performance optimization, such as developing more efficient green synthesis methods, improving the purity and yield of the four products, or discovering new application scenarios, the competitiveness will rise.
From this perspective, the competitiveness of these four products in the market depends on their characteristics, applications, costs, and innovation factors. If properly managed, it is not difficult to achieve good results in the market.