As a leading 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main application fields of 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) fluorobenzene
4- (4,4,5,5-tetramethyl-1,3,2-dioxane-2-yl) borobenzene, which is widely used in the field of organic synthesis. In medicinal chemistry, the Suzuki-Miyaura reaction can be used to form carbon-carbon bonds, providing a key intermediate for the synthesis of complex drug molecules, which helps to develop new drugs, such as anti-cancer and antiviral drugs. In the field of materials science, it can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diode (OLED) materials, because its unique structure can adjust the optoelectronic properties of materials, improve the luminous efficiency and stability of OLEDs; it can also prepare organic semiconductor materials, promoting the development of organic electronics. In the total synthesis of natural products, it acts as an important synthetic block, participating in multi-step reactions, helping to build the carbon skeleton structure of complex natural products, and realizing the total synthesis of bioactive natural products, laying the foundation for the study of their biological activity and medicinal value.
What are the synthesis methods of 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) fluorobenzene
To prepare 4- (4,4,5,5-tetramethyl-1,3,2-dioxoborocyclopentaborane-2-yl) benzonitrile, the synthesis method is as follows:
First take an appropriate amount of benzonitrile derivative, in the specific position of the aromatic ring of this derivative, and introduce a functional group that can further react under suitable reaction conditions, so as to lay the foundation for the subsequent integration of boron heterocyclopentaborane structure. The reaction of introducing functional groups requires precise control of the reaction temperature, reaction time and the proportion of reactants to ensure the selectivity and yield of the reaction.
Then, prepare the intermediate containing tetramethyl-1,3,2-dioxoboronheterocyclopentaborane. The intermediate is formed by condensation reaction with corresponding boron source and hydroxyl-containing compound in the presence of a specific catalyst. In this process, the selection of catalyst and the regulation of pH of the reaction system are very important, which are related to the purity and generation efficiency of the intermediate.
Then the above-prepared benzonitrile derivative and 1,3,2-dioxyboron heterocyclopentaborane intermediates are coupled under the catalysis of transition metal catalysts. Commonly used transition metal catalysts such as palladium catalysts need to add suitable ligands during the reaction to enhance the activity and selectivity of the catalyst. At the same time, the choice of reaction solvent, the type and amount of base have significant effects on the reaction process and product yield. The reaction is carried out in an inert gas protective atmosphere to avoid oxidation of the reactants and products, and the reaction temperature and time are precisely controlled to make the two effectively couple to generate the target product 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboronyl heterocyclopentaborane-2-yl) benzonitrile. After the reaction, the high-purity product is obtained through post-processing steps such as separation and purification. This series of synthesis steps are closely related, and the optimization of conditions in each step is the key to the final successful preparation of the target product.
What are the physicochemical properties of 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) fluorobenzene
4- (4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentylborane-2-yl) allyl benzene, the physical and chemical properties of this compound are as follows:
Its appearance is often colorless to light yellow liquid or solid, depending on the specific environmental conditions. In terms of boiling point, due to its molecular structure characteristics, it will boil at a certain temperature range under certain conditions, which reflects the intermolecular force and the energy required to overcome this force. The melting point also has its specific value, which is the key temperature point for the mutual transformation of solid and liquid states, indicating the critical condition for the disintegration of the lattice structure and the transformation into a liquid disordered state.
In terms of solubility, the compound exhibits different solubility properties in specific organic solvents according to the principle of similar miscibility. For example, in some polar organic solvents, due to the formation of specific interactions between molecules, it can be better dissolved; in non-polar solvents, the degree of solubility may be limited.
In terms of stability, the boroxy heterocycle and allylbenzene part in its chemical structure endow specific chemical activity and stability. The boroxy heterocycle structure may show certain reactivity under certain conditions, and the allylbenzene structure will also participate in specific chemical reactions. The overall stability depends on the environment and contact chemicals.
Its spectral characteristics are significant, and the vibration absorption peaks of characteristic functional groups can be identified by infrared spectroscopy, such as the corresponding peaks of boroxy bonds and carbon-carbon double bonds, which provide an important basis for structure identification. Nuclear magnetic resonance spectroscopy can reveal the information of nuclei in different chemical environments in molecules, and help to analyze molecular structures and atomic connections. These physicochemical properties are of great significance in organic synthesis, materials science and other fields, laying the foundation for their applications.
What is the market price of 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) fluorobenzene?
I look at what you said about "4- (4,4,5,5-tetramethyl-1,3,2-heterocyclopentylboron-2-yl) borobenzene", which is a specific chemical substance. However, its market price is difficult to sum up.
Because of many factors that affect its price. The first one to bear the brunt is the difficulty of preparation. If the preparation requires complicated processes, rare raw materials are used, and the yield is not high after multiple steps, the cost will increase greatly and the price will be high.
Furthermore, the amount of market demand is also the key. If an industry has strong demand for this product, the supply will exceed the demand, and the price will rise; on the contrary, if the demand is small, the price may stabilize or decline.
The fluctuation of raw material prices also has an impact. The price of raw materials rises, and the price of finished products follows; the price of raw materials falls, and the price of products may have room to decline.
In addition, the scale efficiency, technical level, and transportation costs of manufacturers are all related to prices. Large factories can reduce costs by virtue of their scale advantages; those with advanced technology may increase productivity and reduce energy consumption, which affects pricing. The distance and distance of transportation and different methods also make the cost different.
In summary, the market price of "4- (4,4,5,5-tetramethyl-1,3,2-heterocyclopentylboron-2-yl) borobenzene" varies depending on the difficulty of preparation, market supply and demand, raw material prices, and other cost factors, making it difficult to determine an exact price.
What are the storage conditions for 4- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) fluorobenzene?
The storage conditions of 4- (4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentylborane-2-yl) pyridine are crucial to the properties and stability of this substance.
This substance is quite sensitive to air and moisture, so it should be stored in a dry and inert gas-protected environment. Inert gases such as nitrogen and argon can create an oxygen-free and anhydrous atmosphere, which can effectively prevent it from reacting with oxygen and water vapor in the air.
In terms of temperature, it is usually better to store at low temperature, and it is generally recommended to store in a low temperature environment of -20 ° C. Low temperature can reduce molecular activity and slow down the rate of possible chemical reactions, thus prolonging its shelf life.
The choice of storage container should not be ignored. It is advisable to choose a container with good sealing performance, such as glass bottles or plastic bottles with high barrier properties, and ensure that the cap is tightened to prevent air and moisture from infiltrating.
When using this material, it is also necessary to follow specific operating instructions. It should be carried out in an inert gas-protected glove box to avoid long-term exposure to air. In this way, it can ensure that 4- (4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentylborane-2-yl) pyridine maintains its chemical stability during storage for subsequent experiments or production.