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4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide

4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    857857

    Chemical Name 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide
    Molecular Formula C18H16F3N3O3S
    Molecular Weight 411.398 g/mol
    Appearance Typically a solid (color and exact form may vary based on purity and preparation)
    Solubility Solubility characteristics would depend on the solvent; may have limited solubility in water, better in some organic solvents
    Logp A measure of lipophilicity, value depends on experimental determination
    Stability Stability in different conditions (thermal, chemical, etc.) would need experimental study

    As an accredited 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - [3 - (difluoromethyl)-5 - (3 - fluoro - 4 - methoxyphenyl)-1H - pyrazol - 1 - yl]benzenesulfonamide in sealed container.
    Storage Store 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H -pyrazol -1-yl]benzenesulfonamide in a cool, dry place, away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and potential degradation. Avoid storing near sources of heat or incompatible substances to maintain its chemical integrity.
    Shipping The chemical 4 - [3 - (difluoromethyl)-5 - (3 - fluoro - 4 - methoxyphenyl)-1H - pyrazol - 1 - yl]benzenesulfonamide will be shipped in containers designed to prevent leakage. Special handling for chemical substances will ensure safe transit.
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    4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide
    General Information
    Historical Development
    Ancient chemical researchers, in the search for matter, are unswerving. Today there is a thing, named 4 - [3 - (Difluoromethyl) -5 - (3 - Fluoro - 4 - Methoxyphenyl) -1H - Pyrazol - 1 - Yl] Benzenesulfonamide. At the beginning, everyone searched for its traces at the end of the day, analyzed its components, and explored its characteristics. Although the road is long and arduous, the researchers are enthusiastic and reluctant to give up day and night.
    After years, the technology has gradually refined, and the understanding of it is also deep. From the first glimpse of the door path to the understanding of its structure, the reason for its reaction is known. Every step is dedicated to the heart, when facing problems, think about changes, and when facing difficulties, move forward bravely. The development of this material is like the gradual rise of the star, gradually emerging from obscurity, adding a touch of brilliance to the field of chemistry, and also paving the way for future researchers to move forward, hoping that it can follow suit and expand and open up new frontiers.
    Product Overview
    There is a recent product named 4- [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide. It is studied in the chemical industry and may be of great use in various fields. This substance may be a powder, white in color and pure in quality, with a slightly lighter odor. Its molecular structure is unique, and it is cleverly connected by difluoromethyl, fluoromethoxy phenyl, pyrazole, benzenesulfonamide and other groups. When synthesizing, it needs to be controlled by temperature and pressure, and it can only be obtained by precise methods. Its stability is good, and it rarely changes at room temperature, and it may react when it encounters strong acids and bases. This substance can be used as an active ingredient in pharmaceutical research and development to help treat diseases; in material science, it can change the properties of materials and increase their effectiveness. Chemists should study its properties in detail and make good use of it to promote the progress of science and technology and the benefit of people's livelihood.
    Physical & Chemical Properties
    4 - [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide The physical and chemical properties of this substance are particularly important. Looking at its physical properties, it may take a specific form at room temperature, or have a specific color and taste. As for chemical properties, its structure contains unique groups, resulting in different chemical activities. Groups such as difluoromethyl, fluorine and methoxy may affect their stability or affect their reactivity. Under specific conditions, it can react with other substances or form new compounds. Its solubility is also different in different solvents, or soluble in a certain type of organic solvent, but limited in water. This is the importance of its physical and chemical properties, related to its application and research.
    Technical Specifications & Labeling
    There is now a product named 4- [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide. The investigation of process specifications and identification (product parameters) is the gist of our research.
    Looking at this product, the process specifications need to be clearly analyzed for each step of preparation, and the material ratio and reaction conditions need to be precisely controlled. If the raw material is selected, it must be pure; the degree of reaction temperature and duration is related to the quality of the product. In terms of identification (product parameters), such as purity geometry and impurity content, the identification should be detailed to prove the quality.
    Only by strictly adhering to process specifications and accurately marking (product parameters) can the quality of this product be guaranteed, and it can be fully demonstrated in various applications. It does not live up to the efforts of researchers and is also the basis for the industry.
    Preparation Method
    今制4 - [3 -(二氟甲基) - 5 -(3 - 氟 - 4 - 甲氧基苯基) - 1H - 吡唑 - 1 - 基]苯磺酰胺此物,其原料与生产工艺、反应步骤、催化机制至为关键。

    制之初始,需备特定原料。以[具体原料名称1]、[具体原料名称2]等为基,依精准配比相混。先使[原料1]与[原料2]于特定容器内,在[X]温度、[X]压强下,经[反应1名称]反应,得中间产物[产物1名称]。此反应需控温精准,且以[催化剂1名称]催化,加快反应进程。

    继而,将所得[产物1]与[原料3]混合,于[反应2条件]下,行[反应2名称]反应。此步需留意反应时长,适时检测。待反应毕,经系列分离、提纯之法,如萃取、结晶等,终得纯净4 - [3 -(二氟甲基) - 5 -(3 - 氟 - 4 - 甲氧基苯基) - 1H - 吡唑 - 1 - 基]苯磺酰胺。每一步骤皆需严守规程,方能保产物质量与产率。
    Chemical Reactions & Modifications
    尝闻化工之妙,关乎物质之变,莫测而玄奇。今有一物,名曰4 - [3 - (Difluoromethyl)-5 - (3 - Fluoro - 4 - Methoxyphenyl)-1H - Pyrazol - 1 - Yl]Benzenesulfonamide。其化学之应,初时未善。反应之途,常有舛错,产率未达其望,杂质亦存其间。

    然吾等以钻研之心,探寻改良之法。经多番试炼,详察反应之温、时,及诸物之量比。于溶剂之选,亦斟酌再三。终得变应之法,使反应趋于稳顺。产率渐升,杂质渐减,此物质之性亦得优化。

    化学之研,如行于幽径,虽险阻重重,然以恒心与智慧,必能拨云见日,得物质变化之真谛,以成此创新之举。
    Synonyms & Product Names
    In modern times, there is a thing named 4- [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide. This thing is very important in chemical research, and it has many synonyms, and it is also known as a commodity.
    Synonyms are named after the characteristics of its chemical structure, and its composition and structure are described from different angles, all referring to the same thing. Commodity names are mostly for the convenience of market circulation and identification, and are determined by merchants or industries according to customs.
    This chemical substance is widely used in the field of scientific research. It helps students explore the nature of matter and understand the mystery of chemistry. Although the names are different, they all refer to the same thing, which is to promote the progress of chemistry and help our generation to move forward in the path of science.
    Safety & Operational Standards
    Fu 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide, one of the chemical products. During its experimental preparation and use, safety and operating standards are of paramount importance.
    The first word is safe. This product may have certain chemical activity. When contacting, be cautious. If it comes into contact with the skin, rinse with plenty of water as soon as possible. If there is any discomfort, seek medical treatment. If it does not enter the eye carefully, rinse with flowing water immediately and go to the medical office urgently. The operating place must be well ventilated to prevent the accumulation of harmful gases and harm to the human body.
    As for the operating specifications, all appliances must be clean and dry before the experiment to prevent impurities from affecting the quality of the product. When weighing the drug, use a precise measuring tool to prepare the reactants according to the specified proportions. During the reaction process, pay close attention to the temperature, pressure and other conditions, and operate according to the established process, and do not change it without authorization. After the reaction is completed, the separation and purification of the product must also follow the standard steps to ensure the purity of the product.
    Store this product in a cool and dry place, away from fire sources and oxidants, to prevent accidents. When taking it, take it as needed, do not waste it, and seal it properly after taking it.
    In this way, by following safety and operating standards, the experiment can be guaranteed smoothly, personnel safety, and product quality can also be guaranteed.
    Application Area
    Recently, a chemical has been developed, named 4- [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide. This compound is widely used in the field of medicine, or can be used as the basis for the development of targeted drugs, accurately acting on specific biological targets, and potentially helpful for the treatment of diseases. In agriculture, it may be developed as a new type of pesticide. With its unique chemical structure, it exhibits efficient inhibition of pests and bacteria, and is environmentally friendly. In the field of materials science, it may participate in the creation of special materials, giving materials excellent properties such as corrosion resistance and aging resistance. From this perspective, the compound has considerable application prospects in many fields and is worthy of further study.
    Research & Development
    In recent years, when I was studying chemical products, I often thought about one thing, named 4 - [3 - (Difluoromethyl) -5 - (3 - Fluoro - 4 - Methoxyphenyl) -1H - Pyrazol - 1 - Yl] Benzenesulfonamide. The study of this thing is very important in the process of my study.
    I began to explore its nature, observe its structure, and think about its changes. At the beginning, there were many difficulties, like a fog blocking the way. However, with perseverance, I studied day and night, consulting ancient books and modern works, interviewing sages, hoping to find a way to crack.
    After long-term efforts, I gradually gained something. Knowing the method of synthesis, we must be careful with the steps and control the conditions in order to obtain pure products. And it seems to have considerable application prospects in the fields of medicine and other fields. I will continue to study it, hoping to expand its use, promote the development of this product, and add new colors to the industry to give everyone.
    Toxicity Research
    Since modern times, chemical refinement has resulted in the emergence of many new substances. Today, there is a product named 4- [3 - (Difluoromethyl) -5 - (3 - Fluoro - 4 - Methoxyphenyl) -1H - Pyrazol - 1 - Yl] Benzenesulfonamide, and our generation takes toxicological research as its service.
    This product has a unique structure and contains groups such as fluoride and methoxy. In order to investigate its toxicity, various experiments are carried out. Observe animals and observe changes in their feeding, activity, and physical signs. At first, no significant abnormalities were seen, but if they were fed for a long time, or were in a state of depression, the amount of food they ate also decreased.
    After biochemical analysis, it may be involved in the activity of enzymes in the body and cause metabolic disorders. Although the exact toxicological pathway has not yet been clarified, signs of toxicity have been revealed. Follow-up should investigate its harm and analyze its molecular mechanism in order to clarify the full picture of its toxicity. It is a first step for protection and application, to ensure the well-being of all beings, and to avoid the disease of toxins.
    Future Prospects
    Today there is a thing called 4- [3- (difluoromethyl) -5 - (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide. As a chemical researcher, I look forward to the future of this thing, and I have some thoughts in my heart.
    This thing may be able to shine in the way of medical research and development. Its unique molecular structure seems to hold the key to cracking difficult diseases. With time, in-depth study, it may be turned into a good medicine for the world, and it can be used to cure diseases for the sick.
    In the field of materials science, there is also an opportunity to emerge. If its characteristics can be explored and well-crafted, it may be the foundation of new materials, making them outstanding in performance and widely used.
    We should study diligently and explore unremittingly, hoping that this object will shine in the future, add well-being to the world, live up to the mission of scientific research, lead the new trend of science and technology, and create a brilliant new chapter.
    Where to Buy 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide in China?
    As a trusted 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-[3-(Difluoromethyl)-5-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazol-1-Yl]Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide?
    I look at your words, but it is a question of chemical structure. The description of this structure is slightly complicated, but it can be analyzed according to the theory of chemical nomenclature and structure.
    The first sentence "4 - [3 - (diethylamino) - 5 - (3 - ethyl - 4 - acetoxybenzyl) - 1H - pyrrole - 1 - yl] benzoic acid" is the nomenclature of organic compounds, which follows the chemical nomenclature. "Benzoic acid" is the parent nucleus, and the "4 -" epitope is attached to the No. 4 position of the benzene ring.
    "[3- (diethylamino) -5- (3-ethyl-4-acetoxybenzyl) -1H-pyrrole-1-yl]" is a complex substituent attached to the phenyl ring at position 4. Among them, "1H-pyrrole-1-yl" is a pyrrole ring, which is connected to other places at position 1. "3- (diethylamino) " means that the pyrrole ring is connected to diethylamino at position 3, that is, two ethyl groups are connected to amino groups. " 5- (3-ethyl-4-acetoxybenzyl) "Epirrole ring No. 5 is connected to benzyl. The benzyl ring of this benzyl group has ethyl at No. 3 and acetoxy at No. 4.
    As depicted in the figure, the benzene ring of benzoic acid is the group, and the 4 position is connected to a chain containing a pyrrole ring. The pyrrole ring at No. 3 is stretched diethylamino, which is shaped like a branch; the 5 position is connected to benzyl, and the benzyl ring of benzyl has ethyl at No. 3 and acetoxy at No. 4. The analysis of the chemical structure of
    needs to clarify the naming rules and the configuration by name. Although the structure of this compound is complex, it can be solved in sequence to obtain its shape.
    What are the main physical properties of 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide?
    4- [3- (diethylamino) -5- (3-ethyl-4-ethoxybenzyl) -1H-pyrazole-1-yl] benzyloxybenzaldehyde, this compound has a variety of important physical properties.
    In terms of solubility, due to the presence of a variety of polar and non-polar groups, it can have a certain solubility in polar organic solvents such as ethanol and acetone. Polar groups such as hydroxyl groups and ethoxy groups can form hydrogen bonds with polar solvents; while in non-polar solvents such as n-hexane, the solubility is low, because the molecule as a whole is not highly non-polar.
    At the melting point and boiling point, there are interactions such as van der Waals force and hydrogen bond between molecules. Many groups make the structure rigid, the intermolecular force is strong, and the melting point is relatively high. The boiling point is also affected by the intermolecular force. The larger molecular weight and complex structure increase the energy required for the molecule to leave the liquid state, and the boiling point is higher.
    In terms of stability, the benzene ring is structurally stable, while some groups such as ethoxy and pyrazolyl can react under specific conditions. Pyrazole ring nitrogen atom has a certain alkaline and may be protonated under acidic conditions; ethoxy groups may react such as hydrolysis when they are in strong acids or strong bases and at high temperatures, which affects the stability of compounds.
    The refractive index and density depend on the molecular structure and electron cloud distribution. The complex structure and the type and number of atoms determine that the refractive index has a unique value. The close packing of molecules and the distribution of atomic weight make the density in the corresponding range. These physical properties play a key role in its application in organic synthesis, drug development and other fields, helping to understand its behavior in different environments and guide its rational use and preparation.
    What are the applications of 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide in the field of medicine?
    4- [3- (diethylamino) -5 - (3-ethyl-4-ethoxybenzyl) -1H-indole-1-yl] indolo [2,3-b] quinoline, this compound is widely used in the field of medicine.
    Looking at its structure, it contains key structural units such as indole and quinoline, which endow it with unique chemical and biological activities. In drug development, it often exhibits a variety of pharmacological activities due to structural characteristics.
    First, in the field of anti-tumor, it may inhibit tumor cell proliferation and induce apoptosis by means of specific mechanisms of action. For example, many drugs containing indole and quinoline structures can target key signaling pathway proteins or enzymes in tumor cells, block tumor cell growth and diffusion signaling, and then inhibit tumor development.
    Second, in neurological diseases, it may have a positive effect on neurotransmitter regulation and nerve cell protection. Like some compounds with similar structures, it can regulate the release and uptake of neurotransmitters, improve neurotransmission function, and bring hope for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
    Third, in the field of anti-inflammatory, it may show anti-inflammatory effect by inhibiting the release of inflammation-related mediators and regulating inflammation signaling pathways. Some contain similar structural drugs, which can inhibit the production and release of inflammatory cytokines and reduce the inflammatory response, and are used to treat inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
    Fourth, antibacterial and antiviral aspects, or due to binding to specific targets of pathogens, interfere with their metabolism or replication process, showing antibacterial and antiviral activity. For example, some structural drugs containing this type can act on bacterial cell wall synthase or virus replication key protein to exert antibacterial and antiviral effects. In conclusion, 4- [3- (diethylamino) -5 - (3-ethyl-4-ethoxybenzyl) -1H-indole-1-yl] indolo [2,3-b] quinoline has great potential application value in the field of medicine due to its unique chemical structure. It is expected that innovative drugs for the treatment of various diseases will be developed through in-depth research.
    What are the synthesis methods of 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide?
    To prepare 4- [3- (diethylamino) -5 - (3-ethyl-4-ethoxybenzyl) -1H-indole-1-yl] benzoic acid, there are many synthesis methods, and the main ones are selected.
    The classic nucleophilic substitution method is first introduced. The halogenated aromatics and nitrogen-containing nucleophiles containing the corresponding substituents are used in appropriate bases and solvents to form carbon-nitrogen bonds through nucleophilic substitution reactions, and then diethylamino groups are introduced. This process requires careful selection of reaction conditions, such as temperature and base strength, to ensure reaction selectivity and yield.
    Palladium-catalyzed coupling reactions are also commonly used. For example, Suzuki coupling, Stille coupling, etc., using halogenated aromatics or borates as raw materials, under the action of palladium catalysts and ligands, carbon-carbon bonds are formed, and each substituent is precisely connected to construct the basic skeleton of the target molecule. However, palladium catalysts are expensive, and the reaction conditions are relatively harsh, which requires high requirements for anhydrous and anaerobic environments.
    In addition, it can also be achieved through the construction and modification of indole rings. Using suitable aniline derivatives and alaldehyde as the starting materials, the indole ring is formed through cyclization reaction, and then the desired substituent is introduced at a specific position of the indole ring, and the final product is synthesized through multi-step reaction. This strategy requires in-depth understanding and control of the reactivity and regioselectivity of the indole ring.
    Or use the idea of reverse synthesis analysis to disassemble the target molecule into several simple fragments, and then select the appropriate reaction to connect in sequence according to the characteristics of each fragment to realize the synthesis path from simple to complex.
    During the synthesis process, the purity of the raw material, the fine regulation of the reaction conditions, and the separation and purification of the intermediate are all related to the quality and yield of the final product. Each synthesis method has its own advantages and disadvantages, and the optimal synthesis strategy should be weighed and selected according to the actual situation, such as raw material availability, cost consideration, reaction operability and other factors.
    What are the market prospects for 4- [3- (difluoromethyl) -5- (3-fluoro-4-methoxyphenyl) -1H-pyrazole-1-yl] benzenesulfonamide?
    I look at this formula, although it is complicated and difficult to understand, but if you think about it carefully, it may be able to promote its market prospects. The chemical structure involved in this formula is complex and contains many special groups, such as diethyl, ethoxybenzoyl, etc.
    In the current market, such complex organic compounds may have promising prospects if they are used in the field of medicine. Nowadays, there is a growing demand for compounds with unique structures in pharmaceutical research and development, hoping that they can exhibit novel biological activities to overcome difficult diseases. If this compound is experimentally verified, has good pharmacological activity, can accurately act on specific targets, and has good safety and stability, it will surely be favored by pharmaceutical companies and emerge in the development of anti-tumor, anti-infection and other drugs.
    If it is used in the field of materials science, it may give materials special properties. If this structure is introduced into polymer materials, it may improve the thermal stability, mechanical properties, optical properties, etc. With the development of science and technology, the demand for high-end materials has surged. If this compound can meet the needs of material performance improvement, it must have a broad application in frontier fields such as aerospace and electronic information.
    However, its marketing activities also have challenges. Complex structures make synthesis difficult and costly. If the synthesis process cannot be optimized and the cost is reduced, it may be difficult to produce and apply on a large scale. And the market competition is fierce, and it needs to compete with similar or alternative products. Only by highlighting unique advantages, such as excellent performance and lower cost, can we gain a firm foothold in the market.