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4-(2-Bromoethyl)-1-Fluorobenzene

4-(2-Bromoethyl)-1-Fluorobenzene

Hongda Chemical

Specifications

HS Code

492371

Chemical Formula C8H8BrF
Molecular Weight 203.05
Appearance Liquid (usually)
Boiling Point Data depends on purity and conditions
Melting Point Data depends on purity and conditions
Density Data depends on conditions
Solubility In Water Low solubility, hydrophobic
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Flash Point Data depends on purity and conditions
Vapor Pressure Data depends on temperature and conditions
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-(2-Bromoethyl)-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4-(2 - bromoethyl)-1 - fluorobenzene in a sealed, chemical - resistant bottle.
Storage 4-(2 - bromoethyl)-1 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of ignition. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Due to its potentially hazardous nature, store it separately from oxidizing agents, acids, and bases to prevent chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 4-(2 - bromoethyl)-1 - fluorobenzene is shipped in accordance with strict chemical transport regulations. Packed in suitable, leak - proof containers, it's transported by approved carriers to ensure safe delivery while minimizing environmental and safety risks.
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4-(2-Bromoethyl)-1-Fluorobenzene 4-(2-Bromoethyl)-1-Fluorobenzene
General Information
Historical Development
4- (2 - Bromoethyl) -1 - Fluorobenzene is also an organic compound. Its historical development can be traced back to the past, the evolution of chemistry, and many talents are dedicated to organic synthesis. At the beginning, organic chemistry was still in its infancy, and the exploration of complex compounds was only the beginning.
With the passage of time, science and technology have advanced, analytical methods have become increasingly refined, and synthesis methods have been continuously refurbished. The synthesis of this compound has been studied by generations of chemists. In the early days, due to technology, the synthesis was difficult and the yield was quite low. After unremitting efforts, new reactions and new reagents came out, and the synthesis path became wider. Many scholars have conducted in-depth research on its structure and properties, paving the way for its application in materials science, drug development and other fields. From this perspective, the development of 4- (2 - Bromoethyl) -1 - Fluorobenzene is a testament to the continuous progress and breakthroughs in the history of chemistry.
Product Overview
Today there is a substance called 4- (2 - Bromoethyl) -1 - Fluorobenzene. Its shape is also unique. Looking at its structure, on the benzene ring, the fluorine atom and the bromoethyl group each have one place, and the layout is exquisite.
This substance has a wide range of uses and is often a key raw material in the field of organic synthesis. It can be converted into various derivatives through various reactions, laying the foundation for the creation of new compounds.
The preparation method requires a precise process. Through a specific chemical reaction path, with suitable reagents and conditions, it is possible to obtain this product by promoting the interaction of various reactants. However, the preparation process requires careful control of all aspects, such as temperature, reaction time, and the proportion of reactants. A slight difference in the pool may cause the product to be impure or affect the yield.
In summary, although 4- (2 - Bromoethyl) -1 - Fluorobenzene is a microscopic product, it is of great value in the process of chemical research and synthesis.
Physical & Chemical Properties
Today there is a substance named 4- (2 - Bromoethyl) -1 - Fluorobenzene. The physical and chemical properties of the substance are of great importance to researchers. In terms of physical properties, its color state may be colorless and transparent, such as the clear glass, at room temperature, or in a liquid state, with fluidity, like a stream. Its boiling point and melting point are fixed, which are inherent properties of the substance.
In terms of its chemical properties, it is active because of the groups containing bromine and fluorine. Bromine groups can lead to the reaction of nucleophilic substitution, just like magnets lead to iron, and other substances are easy to replace. Fluorine groups make the distribution of molecular electron clouds different from usual, affecting their chemical combination with others. The synergy between the two makes this substance in the field of organic synthesis, like a sharp blade in the sheath, a new path for chemical research, adding thousands of possibilities.
Technical Specifications & Labeling
Today there is a product named 4- (2 - Bromoethyl) -1 - Fluorobenzene. The technical specifications and identification (commodity parameters) of this product are really crucial.
To make this product, specific methods need to be followed. The selection of raw materials and reaction conditions are strictly regulated. The raw materials need to be pure, and the reaction temperature, duration, pressure, etc. should be precisely controlled. A slight difference will affect the quality of the product.
As for the label, the characteristics of this product should be specified in detail. Its chemical structure and physical properties, such as melting point, boiling point, density, etc., must be clearly marked. This is so that the user can understand its properties and use it properly. And on the packaging, safety warnings are also indispensable to inform people of the possible hazards of this product and prevent problems before they occur. In this way, only in order to ensure the smooth production and use of this chemical.
Preparation Method
To prepare 4- (2 - Bromoethyl) -1 - Fluorobenzene, the raw materials and production process are the key. Fluorobenzene is taken as the starting material, and it can be reacted with bromoethane by Fu-gram alkylation. This reaction needs to be carried out under the catalysis of Lewis acid such as anhydrous aluminum trichloride before it can occur smoothly. The reaction steps are as follows: First, the fluorobenzene and the catalyst are co-placed in the reactor, stirred evenly, and then slowly added bromoethane dropwise, and the temperature control reaction is carried out to make the reaction sufficient.
After the reaction is completed, the target product can be obtained by separation and purification. When separating, the catalyst and other impurities are first washed with water, and then distilled to divide 4- (2 - Bromoethyl) -1 - Fluorobenzene according to the difference in the boiling point of each substance. In this process, precise temperature control is required to prevent the decomposition of the product or side reactions.
In order to promote the efficient and stable reaction, a suitable catalytic mechanism should also be constructed. Such as optimizing parameters such as catalyst dosage, reaction temperature and time to improve the yield and purity of the product. In this way, high-quality 4- (2 - Bromoethyl) -1 - Fluorobenzene can be obtained.
Chemical Reactions & Modifications
The chemical modification of 4- (2 - Bromoethyl) -1 - Fluorobenzene compounds is the key to chemical research. The reaction of this compound, or the nuclear substitution involved, the activity of the atom, leads to the reaction. Its bromine atom, the sexual activity, is easy to be attacked by the nucleus, resulting in the generation of substitutes.
However, if you want to do something good, the modification cannot be ignored. Or integrate and reverse parts, such as the degree of dissolution, in order to promote the effect of reaction and increase the quality of the product. Or repair the molecule and add the base to improve its properties, so as to obtain better performance.
In the field of chemical synthesis, gain insight into the anti-chemical properties of this compound, study the modification method carefully, and seek the necessary reasons for new materials and new materials.
Synonyms & Product Names
Today there is a thing called 4- (2 - Bromoethyl) -1 - Fluorobenzene. The same trade name of this thing is also according to our remarks.
The name of the old thing is many, and it varies depending on the name of the same thing, or because of the difference of the same person, or due to the difference of the region. The trade name is often taken by merchants to recognize its characteristics or uses.
4- (2 - Bromoethyl) -1 - Fluorobenzene, or other names, all refer to this thing. The exploration of its similarity can help us better understand the origin of this thing, and it is beneficial to exchange and research and exploration. The test of trade names can be used for commercial work, and the market needs.
We, the researchers, must study the same product name of this object to clarify its full picture, and promote the next step of research. We can all build on the use and development of this object.
Safety & Operational Standards
4- (2 - Bromoethyl) -1 - Fluorobenzene Safety and Operation Specifications
Fu 4- (2 - Bromoethyl) -1 - Fluorobenzene, a commonly used reagent for organic synthesis. It is active, and during the experimental operation, it is necessary to strictly abide by the safety and operation specifications to ensure the safety of the experimenter and the smooth experiment.
#1. Storage Method
This compound should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight to prevent decomposition. Where it is stored, the temperature should be constant, and it should not be too high or too low. It also needs to be placed separately from oxidizing agents, strong bases, etc., because contact with it may cause violent reactions and cause danger. The packaging must be tight to prevent it from leaking.
#2. Rules of Operation
When operating, the experimenter must wear appropriate protective equipment. Wear protective glasses to protect the eyes from splashes; wear experimental clothes to prevent them from contacting the body; wear protective gloves and choose chemical-resistant materials, such as nitrile gloves, to prevent skin contact with them.
Operate in a fume hood to ensure air circulation, expel volatile gas, and reduce the concentration of harmful substances in the air. During the operation, the action should be stable and careful, so as not to collide the container to avoid rupture and leakage. Take the reagent, use clean and suitable equipment, and take it accurately according to the experimental needs, not more or less.
If it accidentally touches the skin, quickly rinse with plenty of water, followed by soap. If it enters the eyes, immediately rinse with running water and seek medical treatment. In case of leakage, cut off the fire source first, because the compound is flammable. Then adsorb with sand, vermiculite, etc., collect and dispose of it properly. Do not discard it at will to avoid polluting the environment.
In short, in the research and use of 4- (2-Bromoethyl) -1 - Fluorobenzene, safety is the first priority, and the operation is in accordance with regulations to avoid disasters and achieve the purpose of the experiment.
Application Area
Today there is a product, named 4- (2 - Bromoethyl) -1 - Fluorobenzene, which has extraordinary uses in various application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs, or treat diseases, or relieve diseases, and seek well-being for the health of the world. In the field of material science, it can be integrated into various materials through special processes to increase their properties, such as making materials have better stability and corrosion resistance to meet the needs of different scenarios. In the fine chemical industry, based on this, multiple fine chemicals can be derived, which are widely used in daily use, beauty and many other aspects, so that the product quality is improved and the function is more abundant. This substance shines like a pearl in various application fields, plays an important role, and has a very broad prospect.
Research & Development
Since modern times, chemical refinement has emerged in an endless stream. Today, 4- (2 - Bromoethyl) -1 - Fluorobenzene is the object of my dedicated research.
At the beginning, explore its synthesis method, after repeated trials, prepare various raw materials, and adjust the temperature. Or in a flask, make various things blend and react, observe its changes, and record data in detail for accuracy.
Then, study its properties. Observe its color and shape, measure its melting point, and investigate its solubility. Explore its reactivity in different media, and gain insight into its chemical properties.
As for the application prospect, there are also considerations. Thinking about it can be used to create new drugs to treat human diseases; or to help material innovation and make material properties more excellent.
I will work hard and work hard on this, hoping to make breakthroughs, contribute to the development of chemistry, and hope that this thing will bloom in the world, benefit all people.
Toxicity Research
Tasting and smelling the nature of things is related to human use, and the study of toxicology cannot be ignored. Today's research on 4- (2 - Bromoethyl) -1 - Fluorobenzene this thing.
Examine its quality and observe its behavior in various environments. In the field of biochemistry, explore its sympathetic with various things, observe the change of cells and the response of enzymes. Or enter the body, follow the bloodline, invade the viscera, and observe its damage.
After various experiences, I know that its strong nature can disrupt the order of cells and harm the nervous system. And this thing is difficult to eliminate for a long time, and it is also harmful to the ecology, disturbing the chain of living things.
Therefore, when studying the toxicity of this substance, be careful and careful to understand its harm. In order to prevent and treat, ensure the safety of all living beings, and protect the ecology in peace, this is the important task of our generation to study toxicity.
Future Prospects
The product of 4- (2 - Bromoethyl) -1 - Fluorobenzene has extraordinary potential. This product can be used in various fields of chemistry, or it can open up a new path. The future development should be used in the synthesis of exquisite drugs to help doctors overcome difficult diseases and save patients from sinking diseases. It is also expected to be used in the creation of advanced materials to make utensils have strange properties and add brilliance to engineering skills. Although there may be thorns in the road ahead, we chemists should have tenacity and unremitting research. With time, we will be able to stimulate the potential of this product, bring well-being to the world, and unfold the grand picture of the future, so that it will shine in various fields, become an unfinished great cause, and fulfill our ambitions.
Where to Buy 4-(2-Bromoethyl)-1-Fluorobenzene in China?
As a trusted 4-(2-Bromoethyl)-1-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-(2-Bromoethyl)-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (2 - Bromoethyl) -1-Fluorobenzene?
4- (2-bromoethyl) -1-fluorobenzene is an important intermediate in organic synthesis and is widely used in many fields such as medicine, pesticides and materials science.
In the field of medicine, this compound can be used as a key intermediate for the synthesis of a variety of drugs. Due to its specific chemical structure, it can participate in many organic reactions to construct molecular structures with biological activity. For example, when developing drugs to treat specific diseases, it can be used as a starting material to precisely introduce bromine and fluorine atoms through a series of chemical reactions. This diatom has a significant impact on the activity, lipophilicity and metabolic stability of drug molecules. With the modification and optimization of the molecular structure of the drug, the efficacy of the drug can be improved and the toxic and side effects can be reduced.
In the field of pesticides, 4- (2-bromoethyl) -1-fluorobenzene also has important applications. It can be used as a key component in the synthesis of high-efficiency and low-toxicity pesticides. The presence of bromine and fluorine atoms can enhance the effect of pesticides on target organisms, and improve the stability and durability of pesticides. After rational design and synthesis, pesticides based on this compound can exhibit good control effects on specific pests, bacteria or weeds, and have relatively little impact on the environment, which is conducive to the sustainable development of agriculture.
In the field of materials science, this compound can participate in the synthesis of new organic materials. For example, when preparing polymer materials with special properties, introducing them into the polymer main chain or side chain as structural units can endow the material with unique physical and chemical properties, such as improving the solubility, thermal stability, and optical properties of the material. In turn, it can meet the special needs of different fields for material properties and promote the development and innovation of materials science.
In conclusion, although 4- (2-bromoethyl) -1-fluorobenzene is an organic compound, it plays an indispensable role in many important fields by virtue of its unique chemical structure and reactivity, providing key support for the progress of related industries.
What are the physical properties of 4- (2 - Bromoethyl) -1-Fluorobenzene?
4- (2-bromoethyl) -1-fluorobenzene is one of the organic compounds. Its physical properties are quite impressive, let me tell them one by one.
First of all, its appearance, under room temperature and pressure, is mostly colorless to light yellow liquid, clear and has a special appearance, which can be seen and distinguished. Looking at its color, light yellow rhyme, slightly translucent, like the wonderful color of the morning light.
As for the smell, it often has a special aromatic smell. Although it is not as rich as flowers, it also has a unique taste. You can feel its unique charm when you smell it.
When it comes to the boiling point, it is about a certain temperature range, which is the key to maintaining the transition from liquid to gaseous state. The value of its boiling point varies slightly due to environmental factors, but it is roughly within a certain range. If it is accurately measured, it should be based on experiments.
Melting point is also an important physical property. Under the melting point of this substance, it is in a solid state and has a stable structure. The value of the melting point is also fixed, which is the manifestation of the material's own characteristics and is an important basis for distinction and identification.
In terms of solubility, it has good solubility in organic solvents, such as ethanol, ether, etc., and can be fused with it. However, in water, the solubility is relatively limited, mostly floating on water, and it is difficult to integrate with water.
Density can also not be ignored, heavier than water, placed in water, slowly sinking to the bottom, the value of its density, characterizing its mass per unit volume, is the inherent properties of matter.
These physical properties are of vital significance in many fields of chemical research and industrial production. It can help researchers understand its characteristics and apply appropriate methods for synthesis, separation and other operations, which are indispensable for the progress of chemistry and the development of industry.
Is 4- (2 - Bromoethyl) -1-Fluorobenzene Chemically Stable?
The stability of the chemical properties of 4 - (2-bromoethyl) -1 -fluorobenzene depends on many factors. In this compound, the fluorine atom is connected to the benzene ring. Due to the high electronegativity of fluorine, the electron cloud density of the benzene ring can be affected by induction effect and conjugation effect, which reduces the electron cloud density of the benzene ring.
Bromoethyl is connected to the benzene ring, and the bromine atom has a certain electron-withdrawing property. However, under specific reaction conditions, the bromine atom can exhibit activity and is prone to nucleophilic substitution.
Looking at the whole compound, the existence of the conjugate system of the benzene ring gives it partial stability to a certain extent. However, there are both electron-absorbing fluorine atoms and reactive bromoethyl groups on the benzene ring, making it also have certain reactivity.
At room temperature and pressure without special reagents, 4- (2-bromoethyl) -1-fluorobenzene is relatively stable. However, when encountering nucleophiles, bromine atoms of bromoethyl groups are easily attacked by nucleophiles, and substitution reactions occur to form new compounds. And if it is in an environment of high temperature, light or a specific catalyst, its reactivity may be further enhanced, and reactions such as elimination and rearrangement occur. Therefore, the chemical properties of 4- (2-bromoethyl) -1-fluorobenzene are not absolutely stable. Under different conditions, they may be stable or active, depending on the external environment and the reagents encountered.
What are the synthesis methods of 4- (2 - Bromoethyl) -1-Fluorobenzene
4- (2-bromoethyl) -1 -fluorobenzene is also an organic compound. The method of its synthesis is mostly described in ancient books.
One method can be used as nucleophilic substitution. Take 1-fluorobenzene as the group first and make it interact with bromoethyl-containing reagents. For example, under appropriate conditions, 1-fluorobenzene and 2-bromoethanol are supplemented with suitable bases, such as potassium carbonate. The alkali can take the hydroxyl hydrogen of 2-bromoethanol and make it into a negative ion. This negative ion has strong nucleophilicity and can attack the benzene ring of 1-fluorobenzene. After nucleophilic substitution, 4- (2-bromoethyl) -1 -fluorobenzene is obtained. When reacting, pay attention to the choice of temperature and solvent. If the temperature is too high, it may cause a cluster of side reactions; the nature of the solvent is also related to the rate and yield of the reaction. Polar aprotic solvents such as dimethylformamide (DMF) are commonly selected because they are soluble in the reactants and are beneficial to nucleophilic substitution.
The second method can be obtained by the coupling reaction of halogenated hydrocarbons. First, fluorine-containing halobenzene, such as 1-fluoro-4-halobenzene (the halogen atom can be iodine and other highly active ones), is prepared, and then coupled with Grignard's reagent of 2-bromoethyl group. Grignard's reagent is prepared with magnesium and 2-bromoethane in anhydrous ether and other solvents. When the two meet, they are coupled and reacted to form the target product. However, this reaction requires strict reaction environment, which requires anhydrous and anoxic, and the Geyne Grignard's reagent has high activity. It decomposes when exposed to water and oxygen, making the reaction difficult.
And the aromatic electrophilic substitution is used as the beginning. Before the benzene ring, a suitable positioning group is introduced, so that the subsequent reaction For example, the active group is introduced first to increase the activity of the benzene ring and locate it to the desired position. Then attack the benzene ring with an electrophilic reagent containing bromoethyl group and replace it with an aromatic electrophilic to obtain the target compound. However, in this process, the selection of the positioning group and the control of the reaction conditions are all key. If there is a slight difference, the product is impure.
What are the precautions for 4- (2 - Bromoethyl) -1-Fluorobenzene in storage and transportation?
4- (2-bromoethyl) -1 -fluorobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
Bear the brunt, when storing, must choose a cool, dry and well-ventilated place. This compound is easy to decompose when heated, and the high temperature environment may cause its chemical properties to mutate and even cause danger, so it is important to avoid heat.
Furthermore, because of its certain toxicity and irritation, the storage place must be kept away from food, beverages and places where people and animals are active frequently to prevent inadvertent contact or inhalation, endangering life and health. And it needs to be stored in a sealed container to prevent volatilization and escape, which not only maintains its own stability, but also avoids pollution to the surrounding environment.
As for transportation, the carrier should have professional qualifications and experience. The means of transportation should also ensure that it is clean, dry and free of other substances that may react with it. During transportation, closely monitor the temperature and humidity to avoid large fluctuations in temperature and humidity.
In addition, whether it is storage or transportation, the relevant personnel should be familiar with the characteristics of this compound and emergency treatment methods. In the event of an unexpected situation such as leakage, it can be responded to quickly and properly to minimize the harm. After all, proceed with caution and take comprehensive precautions to ensure the safety of 4- (2-bromoethyl) -1-fluorobenzene during storage and transportation.