4-(1-Piperazino)Fluorobenzene

Hongda Chemical

Specifications

HS Code	601707
Chemical Formula	C10H13FN2
Molecular Weight	180.22
Appearance	Solid (Typical description, actual may vary)
Melting Point	Data may vary by source
Boiling Point	Data may vary by source
Solubility In Water	Low solubility (General expectation)
Solubility In Organic Solvents	Soluble in some organic solvents (e.g. ethanol, acetone)
Density	Data may vary by source
Flash Point	Data may vary by source
Purity Typically Available	Varies, e.g. 95%+, depends on supplier

As an accredited 4-(1-Piperazino)Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4-(1 - piperazino)fluorobenzene packaged in a sealed, labeled container.
Storage	Store 4-(1 - piperazino)fluorobenzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container to prevent moisture and air exposure. Since it's a chemical, store it separately from incompatible substances, such as oxidizing agents and strong acids, to avoid potential chemical reactions.
Shipping	4-(1 - piperazino)fluorobenzene is shipped in well - sealed containers, following strict chemical transportation regulations. Packaging ensures protection from external factors. Shipment is handled by carriers experienced in chemical logistics.

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General Information

Historical Development

Guanfu 4- (1-Piperazino) Fluorobenzene is derived from the study of chemistry in the past. At the beginning, Zhu Xian worked hard in the laboratory and explored with various techniques. At that time, the conditions were simple, but his ambition remained unchanged. After months of trial and error, the method of preparation was obtained. At the beginning, the yield was meager, and the quality was not perfect. However, the scholars worked tirelessly, and the technology advanced with the passage of time. New reagents and new equipment were gradually introduced, and the preparation technology became more and more mature. The yield was improved, and the quality was also significantly improved. Since the difficult beginning of the past, the progress of the present day depends on the perseverance and wisdom of the chemical researchers of the past generations, which has led to the wide use of this product in the fields of chemical industry and medicine.

Product Overview

4- (1 - Piperazino) Fluorobenzene is a chemical substance that I have been focusing on recently. Its properties are unique, its color is pure and uniform, and it is in a state of fine crystallization. Under the light, it looks like stars twinkling and shines brightly.
The structure of this compound is exquisite, the piperazine group is cleverly connected to the fluorobenzene ring, and the combination of chemical bonds is rigorous and delicate, giving it unique chemical activity. After repeated experiments and investigations, it has been observed that its performance in various reactions is stable and controllable, just like a calm dancer, performing a unique melody on the stage of chemistry.
It has extraordinary potential in the field of organic synthesis. It can be used as a key intermediate, such as the cornerstone of a magnificent building, paving the way for the synthesis of many complex compounds. I am convinced that with time and in-depth research, more hidden values will be discovered, adding brilliant pearls to the palace of chemistry.

Physical & Chemical Properties

The physicochemical properties of 4- (1-piperazinyl) fluorobenzene are quite important. Looking at its morphology, it may be a colorless to light yellow liquid at room temperature, with a certain fluidity. Its boiling point is related to the intermolecular force. Experiments have calculated that it is about a specific temperature range. Due to the interaction between piperazinyl and fluorobenzene groups in the molecular structure, its boiling point shows a corresponding value.
In terms of solubility, it has good solubility in polar organic solvents such as ethanol and acetone. Due to the partial structure of the molecule and these solvents, hydrogen bonds or other intermolecular forces can be formed. However, the solubility in water is poor, which is affected by its non-polar part.
In terms of chemical properties, the nitrogen atom of piperazinyl has a certain alkalinity and can react with acids to form corresponding salts. The fluorobenzene part changes the electron cloud density of the benzene ring due to the electronegativity of the fluorine atom, which affects its electrophilic substitution activity. The physicochemical properties of this compound play a key role in its application in chemical, pharmaceutical and other fields.

Technical Specifications & Labeling

4- (1 - Piperazino) Fluorobenzene is also a chemical product. Its process specification and identification (product parameters) are the key. In the process specification, it is necessary to specify the preparation method, from the selection of raw materials, such as fine selection of reactants, control of their quality and quantity, to the setting of reaction conditions, such as temperature, pressure, and duration, all should be accurate. The reaction equipment also needs to be fit and clean in good condition to ensure a smooth process.
As for the identification (product parameters), the properties, color, taste, and state of the product must be specified in detail. There are standards of purity and limitations of impurities, which are related to its quality. Physical and chemical properties, such as melting point, boiling point, solubility, etc., are also indispensable, providing a user's guide, making it clear and convenient to use, and meeting the essence of process specifications and labels, so that this product can achieve a state of excellence.

Preparation Method

The method of making 4 - (1 - piperazinyl) fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected, such as high-purity fluorobenzene and piperazine, to ensure product quality.
In the production process, the first thing to do is to control the reaction temperature and pressure. In a special reactor, the fluorobenzene and piperazine are mixed in a specific ratio, the temperature is adjusted to a moderate level, about one hundred and twenty degrees Celsius, and the pressure is stabilized at three to five atmospheres. Under this condition, the two can react effectively.
The reaction step is also crucial, first stir the raw material slowly to help it fully contact and initiate the reaction. When there are preliminary signs of reaction, gradually increase the stirring rate to promote the reaction.
The catalytic mechanism depends on high-efficiency catalysts, such as a special metal complex. It can reduce the activation energy of the reaction, accelerate the reaction process, and increase the yield. After these controls, high-quality 4- (1-piperazinyl) fluorobenzene products can be obtained.

Chemical Reactions & Modifications

Nowadays, there is a chemical substance called 4- (1-piperazinyl) fluorobenzene. As a chemical researcher, I often study the reaction and modification of this substance.
Looking at its chemical properties, this substance has a unique structure. Among them, piperazinyl is connected to fluorobenzene, and its reactivity is unique. Among many reactions, if you want to modify it, you must carefully observe its structural characteristics.
In order to find its modification method, you can try to use a specific reagent to initiate its substitution reaction, so that its side chain can be changed, so as to achieve the purpose of performance improvement. Or by changing the reaction conditions, such as temperature, pressure and catalyst type, you can initiate a different reaction path and give it novelty.
In this way, after repeated investigation, we hope to gain insight into the chemical changes of 4- (1-piperazinyl) fluorobenzene, and expand the way for its application in various fields to optimize its performance to meet diverse needs.

Synonyms & Product Names

4 - (1 -piperazinyl) fluorobenzene is also a chemical substance. In the field of chemical industry, it has the same name and trade name. The same name of this substance has gradually accumulated due to the research of scholars and the envoy of industry. The business name is related to the promotion of the city's business and production.
In the process of research, various scientific names gradually emerged, all referring to this thing. Or according to its structure, or according to its nature, to determine the same name. And the establishment of the business name is often in the city, trying to show its differences and attract customers.
The same name and the business name, although different, refer to the same thing. The researcher wants to clarify its quality and explore its nature, and the industry wants to sell its products and expand its market, both of which depend on the authenticity of this name. Therefore, the same name and commercial name of 4 - (1 -piperazinyl) fluorobenzene are of great importance in the progress of the chemical industry.

Safety & Operational Standards

4- (1-piperazinyl) fluorobenzene
Fu4- (1-piperazinyl) fluorobenzene is an important compound in chemical research. In its experiment and production process, safety and operation standards are the key.
The first word is safe. This compound may have certain chemical activity and latent risk. Therefore, in the process of storage, it is necessary to choose a cool, dry and well-ventilated place. It is necessary to keep away from fire and heat sources to prevent chemical reactions caused by heat and cause danger. And it should be stored separately from oxidants, acids, bases and other substances to avoid improper mixing and triggering accidents.
Furthermore, on the operating specifications. The experimenter should wear appropriate protective equipment, such as laboratory clothes, gloves and protective glasses, to prevent the substance from coming into contact with the skin and eyes. If it comes into contact accidentally, rinse with plenty of water immediately and seek medical attention as appropriate. In the operating room, ventilation equipment must be well-ventilated to disperse harmful gases that may be generated. When performing chemical reaction operations, strictly follow the established procedures and parameters. The order of adding reactants, the control of reaction temperature and time should not be slightly different. For example, if it is necessary to heat the reaction, when it is slowly warmed up, closely observe the process and phenomenon of the reaction, and do not act rashly.
In waste disposal, specific norms must also be followed. Waste containing 4- (1-piperazinyl) fluorobenzene should not be dumped at will, but should be collected in accordance with relevant environmental regulations and properly disposed of to avoid pollution to the environment.
In short, in the research and application of 4- (1-piperazinyl) fluorobenzene, strict adherence to safety and operating standards can ensure the safety of personnel, the smooth operation of experiments and the protection of the environment.

Application Area

The application field of 4- (1-piperazinyl) fluorobenzene is quite promising. In the field of medicine, or as a key raw material for the creation of new drugs. The combination of cappiperazinyl and fluorobenzene can have unique pharmacological activities, can act on specific receptors, or regulate biochemical reactions in the body, and is expected to treat various diseases, such as diseases of the nervous system, cardiovascular diseases, etc. In materials science, or can make special functional materials. The special structure of the material may give excellent electrical and optical properties for electronic components, display materials, etc. In organic synthesis, it is often an important intermediate. Through various reactions, a variety of organic compounds are derived, expanding the scope of organic synthesis, and creating new paths for chemical, materials and other industries. It has extraordinary application value.

Research & Development

Since modern times, the art of chemistry has changed with each passing day, and the exploration of substances has changed with each passing day. I have focused on 4- (1-piperazinyl) fluorobenzene, and I have studied it with all my heart.
At the beginning, the knowledge of its properties was still shallow, and only a little bit of its structure was known. However, it was not easy to understand its characteristics and uses. Then I searched the classics, visited various houses, and went into the laboratory in person, and tried repeatedly. Observe the image of its reaction, observe the things it generates, and record the data in detail. I dare not slack off in the slightest.
After months of work, its physical and chemical properties have gradually gained. Knowing that it can react delicately with various things under specific conditions, this discovery paves the way for subsequent research.
Then think about its application, considering industrial production, pharmaceutical research and development and other fields. After many explorations, it has been found that it may be of great use in pharmaceutical synthesis. If it can be used well, it may help the development of medicine.
Although there are some gains now, we know that there is a long way ahead. In the future, we still need to study diligently, hoping to make more breakthroughs in the research and development of 4- (1-piperazinyl) fluorobenzene, and make a little progress for the progress of chemistry.

Toxicity Research

Those who have studied chemical substances in modern times specialize in the study of toxicology. Today there is a thing called 4- (1 - Piperazino) Fluorobenzene, and the study of its toxicity is of great importance.
Examine this substance in detail to explore its implications for people and the environment. Or in the organs and meridians of the human body, there is a risk of damage; in the surrounding water, soil, grass and trees, there is also potential harm.
We must study it with caution and rigorous methods. Examine its materialization in detail, and observe its changes in different situations. Explore the path of its entry into the body, eat it, suck it, or touch it, and what should be done. It is also observed that its decomposition and dissemination in the environment show the wide and narrow harm.
Hope that the study of this toxicity can provide evidence for the safety of everyone and the peace of heaven and earth, so that the use of this substance can seek advantages and avoid disadvantages, and it can be handled well.

Future Prospects

Although this object has not yet appeared in the world, its future prospects are really exciting. It is unique in nature, or it has extraordinary effects in the field of medicine, which can solve the suffering of many diseases. Or it can shine in the world of materials and create unprecedented quality materials. Although the road ahead is uncertain, I firmly believe that with time, everyone will be able to study together and reveal its mysterious veil. At that time, this substance will be able to benefit the people of the world, shine in all fields, become a bright pearl of the future, develop endless potential, and add a touch of light to the world, so as to benefit all people, prosper all industries, and create a new era.

Where to Buy 4-(1-Piperazino)Fluorobenzene in China?

As a trusted 4-(1-Piperazino)Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-(1-Piperazino)Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main application fields of 4- (1-Piperazino) Fluorobenzene?

4 - (1 - piperazinyl) fluorobenzene is one of the organic compounds. Its main application fields are quite wide.
In the field of medicinal chemistry, this compound is often a key intermediate. In terms of creating new drugs, its special chemical structure can be used to construct molecular structures with specific biological activities. For example, when developing therapeutic drugs for specific diseases, 4 - (1 - piperazinyl) fluorobenzene can be used to introduce piperazine groups because it can interact with specific targets in organisms, thereby regulating physiological processes and achieving the purpose of treating diseases.
In the field of materials science, it also has its uses. The preparation of some functional materials can be integrated into the material molecular system to improve the electrical and optical properties of the material by virtue of its structural properties. For example, in the synthesis of some organic optoelectronic materials, adding this compound may optimize the absorption and emission properties of the material to light, laying the foundation for the performance improvement of optoelectronic devices.
In pesticide chemistry, it also shows potential value. Or it can be used as a lead compound, modified and optimized by structure to create new pesticides. Because its structure can bind with specific biomolecules in pests, interfere with the normal physiological activities of pests, achieve efficient insecticidal effect, and may improve the environmental friendliness, which is in line with the current development direction of green pesticides.
In summary, 4- (1-piperazinyl) fluorobenzene has important applications in many fields such as medicine, materials, and pesticides, providing a rich chemical basis and possibility for innovation and development in various fields.

What is the market outlook for 4- (1-Piperazino) Fluorobenzene?

At present, the prospect of 4- (1 -piperazinyl) fluorobenzene in the market is worth exploring. This compound has considerable use in medicine, chemical industry and other fields.
In the pharmaceutical industry, it may be the key raw material for the creation of new drugs. Due to the structural characteristics of piperazinyl and fluorobenzene, it can interact with specific targets in organisms and has potential pharmacological activity. Therefore, with the advancement of medical research, there is a demand for new specific drugs, and 4- (1 -piperazinyl) fluorobenzene is used in drug research and development, or to welcome a broader world.
In the chemical industry, it can be used as an important intermediate for the synthesis of special materials. With its unique chemical structure, it can endow materials with special properties, such as improved material stability and solubility. With the upgrading of the chemical industry, the demand for high-performance special materials has surged, and this compound will also receive more attention and application.
However, its market prospects are not smooth sailing. On the one hand, the complexity and high cost of the synthesis process may restrict its large-scale production and promotion. If there is a breakthrough in synthesis technology, cost reduction and efficiency increase, it is expected to greatly expand market share. On the other hand, the fierce market competition cannot be underestimated. Many enterprises and scientific research institutions are paying attention to this field. If they want to come out on top, they need to continuously innovate and improve product quality and competitiveness.
Overall, although 4- (1-piperazinyl) fluorobenzene faces challenges, the future is still bright under the impetus of the vigorous development of medicine and chemical industry. With time, when the technology is mature and the cost is controllable, it will be able to bloom in the market and make outstanding contributions to the progress of related industries.

What are the production processes of 4- (1-Piperazino) Fluorobenzene?

4- (1 -piperazinyl) fluorobenzene is also an organic compound. Its preparation process is related to multi-step chemical reactions and requires specific reaction conditions and raw materials.
Initially, fluorobenzene-containing compounds are often used as starting materials. This material and appropriate piperazine derivatives are combined in a specific reaction system by nucleophilic substitution reaction. In this reaction, the choice of solvent is very critical. Commonly used solvents, such as polar organic solvents, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO), can improve the solubility of the reactants and make the reaction easier to proceed. The temperature and time of the
reaction also have a significant impact on the yield and purity of the product. Generally speaking, this nucleophilic substitution reaction needs to be carried out under appropriate heating conditions, and the temperature may be between 50 ° C and 150 ° C, depending on the specific reactants and reaction system. The reaction time may take several hours to tens of hours, and the reaction process needs to be closely monitored during this period, which can be observed by means of thin-layer chromatography (TLC).
In order to make the reaction more efficient, it is often necessary to add appropriate bases. Bases can promote the nucleophilicity of piperazine derivatives, and inorganic bases such as potassium carbonate, sodium carbonate, or organic bases such as triethylamine can be used in this reaction system.
After the nucleophilic substitution reaction is completed, the product needs to be separated and purified. Common separation methods include extraction, distillation, etc. During extraction, a suitable organic solvent and aqueous phase can be selected to enrich the product in the organic phase. Then, the organic solvent is removed by distillation and other means to obtain a crude product.
The crude product needs to be further purified to improve its purity. The commonly used purification method is column chromatography. Selecting an appropriate silica gel as the fixed phase and eluting with a suitable eluent can separate the product from the impurities, and finally obtain high-purity 4- (1-piperazinyl) fluorobenzene.
Although there are various changes in this preparation process, the above steps are common approaches, and the conditions and parameters of each step need to be carefully adjusted to achieve satisfactory results.

What are the Quality Standards for 4- (1-Piperazino) Fluorobenzene?

4 - (1 - piperazinyl) fluorobenzene is also an organic compound. Its Quality Standard is related to many factors.
The first appearance should usually be a colorless to light yellow liquid or crystalline. If the appearance is different, such as too dark color or showing an unexpected form, it may involve impurities or poor quality.
The second discussion of purity, this is the key indicator. High purity of 4 - (1 - piperazinyl) fluorobenzene, the purity should be more than 98%, or even higher. Insufficient purity, or due to side reactions in the synthesis process, poor separation and purification, will affect its application efficiency in medicine, chemical industry and other fields. The content of impurities should also be strictly controlled. The amount of specific impurities should be extremely low, covering impurities or interfering with reactions, or causing negative effects during application.
Melting point and boiling point are also important considerations. Its melting point and boiling point should conform to the established range, which can help prove the purity and structural stability of the substance. If the melting point and boiling point deviate from the normal range, it may suggest that the structure of the substance is mutated or contains impurities.
The moisture content cannot be ignored. Generally, it should be kept at a low level, such as less than 0.5%. Excessive moisture or affect the chemical stability of the substance, and may act as a interfering factor in some reactions.
In addition, indicators such as heavy metal content must also follow relevant standards to ensure that they are within the scope of environmental and application safety.
In summary, the Quality Standards of 4 - (1 - piperazinyl) fluorobenzene are based on a number of indicators such as appearance, purity, impurity content, melting point, boiling point, moisture and heavy metal content, etc., to ensure its high quality and suitable for various related uses.

What factors affect the price fluctuation of 4- (1-Piperazino) Fluorobenzene?

4 - (1 - piperazinyl) fluorobenzene is affected by general factors. First, the cost of raw materials is the main factor. The general raw materials required to make this compound, if its price is high, the price of 4 - (1 - piperazinyl) fluorobenzene is also high. Such as piperazine and fluorobenzene-containing raw materials, if their supply is low, or the production cost increases, the cost of 4 - (1 - piperazinyl) fluorobenzene will increase, which will increase its market price.
Second, the supply and demand of the market is very large. If the market demand for 4- (1-piperazinyl) fluorobenzene is strong, if it is widely used in manufacturing, manufacturing, and other industries, the demand will increase greatly, and the supply will be limited, and the price will rise; on the contrary, if the demand is low, the supply will be left behind, and the price will be downward.
Third, the production technology will also have an impact. If there are new technologies and new industries, it can improve the production efficiency, reduce energy consumption, and improve the quality, which can reduce the cost, or cause the price to drop. On the contrary, if the technology is not good, the production efficiency is low, the cost remains high, and the cost will also be affected.
Fourth, policy and legal factors cannot be ignored. The addition of insurance policies may enable production enterprises to increase investment in insurance and increase production costs; the integration of income policies, such as the increase and decrease in the rate of production, will also have a negative impact on the grid. And easy-to-implement policies, such as insurance, easy-to-use barriers, etc., if there is reform, it will affect the export of raw materials and products, which will also affect the grid.
Fifth, the industry is also left and right. There are many enterprises in the same industry, and the industry is fierce. Enterprises can share the market, or they can choose and reduce the strategy. On the contrary, if the market is high, few enterprises can control the supply, and can control the price.