As a leading ((3S,5R)-5-((1H-1,2,4-Triazol-1-Yl)Methyl)-5-(2,4-Difluorophenyl)-Tetrahydrofuran-3-Yl)Methyl 4-Methylbenzenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate
The chemical structure of this compound is analyzed as follows according to the information given:
" (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrimidine-3-yl) methyl + 4-methylbenzenesulfonate".
Where " (3S, 5R) " indicates the configuration of the chiral center, which indicates the atomic spatial arrangement at a specific location of the compound. "5- ((1H-1,2,4-triazole-1-yl) methyl) " means that a substituent based on 1H-1,2,4-triazole-1-yl with a methyl group is attached to the 5th carbon atom. "5- (2,4-difluorophenyl) " indicates that a 2,4-difluorophenyl group is also attached to the 5th carbon atom. "Tetrahydropyrimidine-3-yl) methyl" indicates the presence of a tetrahydropyrimidine structure and a methyl group is attached at its 3rd position. "4-Methylbenzenesulfonate" indicates that the other part of the compound is the ester structure formed by 4-methylbenzenesulfonate. Overall, the compound structure consists of a tetrahydropyrimidine core with a specific chiral configuration, connected to substituents such as triazole, difluorophenyl, methyl, and 4-methylbenzenesulfonate. Each part is connected by specific chemical bonds to form a unique chemical structure.
What is the main use of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroisoxazole-3-yl) methyl 4-methylbenzenesulfonate, which is a key intermediate commonly used in organic synthesis. In the field of medicinal chemistry, it plays a crucial role in the creation of new drugs.
Looking at the process of drug development today, many compounds with specific biological activities are based on (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroisozole-3-yl) methyl 4-methylbenzenesulfonate as the starting material. After a series of delicate chemical reactions, it can finally be converted into drugs with excellent efficacy. For example, in the development of antifungal drugs, based on this intermediate, molecular structures with high antifungal activity can be cleverly constructed, which is of great significance for the treatment of invasive fungal infections.
In addition, in the field of materials science, this compound has also emerged. With its unique chemical structure and properties, it can participate in the preparation of functional materials with unique properties, such as materials with special optical and electrical properties, injecting new vitality into the development of materials science. In the vast world of organic synthesis, it is like a bridge connecting basic research and practical applications, helping scientists develop more novel and practical substances, and promoting many fields to new heights.
What are the synthesis methods of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate
Now there are (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroimidazole-3-yl) methyl 4-methylbenzenesulfonate synthesis method geometry? This is the key question of chemical synthesis.
To prepare this product, you can go through many ways. First, with a suitable starting material, through a substitution reaction, the (1H-1,2,4-triazole-1-yl) methyl is connected to a suitable halogenated hydrocarbon to form an intermediate containing triazole methyl. This halogenated hydrocarbon needs to be carefully selected, and its structure and reactivity are related to the success or failure of the subsequent reaction.
Then, the intermediate is reacted with a compound containing (2,4-difluorophenyl) tetrahydroimidazole-3-yl) methyl, and the two can be combined by means of nucleophilic substitution. This step requires strict control of reaction conditions, such as temperature, solvent, catalyst, etc., which have a great influence on the reaction process and product purity.
Furthermore, for the 4-methylbenzenesulfonate part, it can be introduced by sulfonation reaction. Select a suitable sulfonation reagent and react with the precursor under suitable conditions to successfully connect the sulfonate group to the target structure.
The synthesis process requires repeated experiments and fine regulation of the reaction parameters at each step to obtain pure and high-yield (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroimidazole-3-yl) methyl 4-methylbenzenesulfonate. Every step needs to be careful, and the synthesis path should be continuously optimized according to chemical principles and past experience to achieve the goal.
What is the safety of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate
(3S, 5R) - 5- ((1H - 1,2,4 - triazole - 1 - yl) methyl) - 5- (2,4 - difluorophenyl) tetrahydropyrimidine - 3 - yl) methyl + 4 - methylbenzenesulfonate This product is related to its safety and needs to be observed from multiple aspects.
To observe its chemical structure, it contains specific groups such as triazolyl and phenylfluoryl. Triazole structures are often biologically active in many chemicals, but may lead to latent risks. If there were drugs containing triazoles in the past, although they had antibacterial efficacy, they occasionally had adverse reactions to organisms, or interacted with specific enzymes or receptors in the body, disrupting physiological processes. The introduction of fluorophenyl groups may change their fat solubility and biological activity, but fluoride sometimes has environmental persistence and bioaccumulation problems, and is transmitted through the food chain in the ecosystem, endangering biological communities.
From the theory of preparation process, the raw materials and reagents used in the synthesis process may be toxic and corrosive. If the operation is not in accordance with the specifications, the raw materials will leak, which can pollute the environment and threaten the surrounding organisms. And the control of reaction conditions is also critical. Improper temperature, pressure, etc., may cause frequent side reactions, generate unknown impurities, and make it difficult to identify the safety of the product.
Its application scenarios are also the focus of consideration. If used in the field of medicine, applied to the human body, pharmacology and toxicology must be studied in detail. After animal experiments, its acute and chronic toxicity, teratogenicity, carcinogenicity and mutagenicity are observed. In the clinical trial stage, close monitoring of human reactions is carried out to ensure curative effect while ensuring patient safety. If used as a fungicide in agriculture, etc., it is necessary to consider its residue in crops and its impact on soil microorganisms, beneficial insects and other ecological factors.
In summary, to evaluate the safety of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrimidine-3-yl) methyl + 4-methylbenzenesulfonate, a comprehensive chemical structure, preparation process and application scenarios are required, and a multi-pronged approach is taken to ensure its safe use in various fields.
What is the market prospect of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrimidine-3-yl) methyl 4-methylbenzenesulfonate, which is a rather complex organic compound. The discussion of its market prospects should be viewed from various angles.
In the field of medicine, compounds containing 1,2,4-triazole structures often have significant biological activities, such as antibacterial, antiviral, and antitumor. This compound may have gained popularity in the development of new drugs due to the combination of specific groups it contains. Nowadays, the demand for high-efficiency, low-toxicity and unique mechanisms of action is increasing day by day. If this compound is confirmed to have excellent pharmacological activity by research, it will definitely gain a place in the innovative drug market.
In the field of pesticides, compounds containing fluorine and triazole structures often have high-efficiency bactericidal and insecticidal activities. With the advancement of agricultural modernization, the demand for green, environmentally friendly and efficient pesticides is also on the rise. If this compound exhibits good control effects on crop diseases and pests and is environmentally friendly, it also has broad development space in the pesticide market.
However, there are also challenges to its market prospects. The synthesis of this complex compound may require cumbersome steps and high cost. If the synthesis process cannot be optimized to reduce the cost, its large-scale production and marketing activities may be hindered. Furthermore, the research and development of new drugs or new pesticides must undergo strict safety and efficacy assessments, which takes a long time and costs a lot. Only by successfully passing many barriers can it officially enter the market.
Although this compound has addressable market value due to its unique structure, in order to fully realize its market prospect, it still needs researchers to make unremitting research and exploration in synthesis process optimization, biological activity research and safety assessment.
