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3-(Trifluoromethyl)-4-Iodonitrobenzene

3-(Trifluoromethyl)-4-Iodonitrobenzene

Hongda Chemical

    Specifications

    HS Code

    514575

    Chemical Formula C7H3F3INO2
    Molar Mass 329.004 g/mol
    Appearance Solid
    Color Yellowish
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Density Data needed
    Flash Point Data needed
    Purity Typically sold with high purity, e.g., 95%+

    As an accredited 3-(Trifluoromethyl)-4-Iodonitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3-(trifluoromethyl)-4-iodonitrobenzene packaged in a sealed glass bottle.
    Storage 3-(Trifluoromethyl)-4-iodonitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture and air exposure, which could potentially lead to decomposition. Store separately from incompatible substances like oxidizing agents and reducing agents to avoid chemical reactions.
    Shipping 3-(Trifluoromethyl)-4-iodonitrobenzene is shipped in well - sealed containers, following strict chemical transport regulations. Special care is taken to prevent breakage and exposure, ensuring safe transit to the destination.
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    3-(Trifluoromethyl)-4-Iodonitrobenzene 3-(Trifluoromethyl)-4-Iodonitrobenzene
    General Information
    Historical Development
    3 - (trifluoromethyl) - 4 - iodinitrobenzene is also a chemical substance. Its origin, beginners in the field of chemistry to study, to seek new quality, through years of exploration, trial and error, to obtain the synthetic clue of this substance.
    In the past, all the sages used simple methods, thinking hard, and gradually clarified its reaction mechanism. Initially, it can only be prepared in small quantities, the cost is high, and it is difficult to use. However, the ambition of the scholar is strong, and it has not been stopped due to difficulties.
    Years have passed, and the technology is progressive. The refinement of the instrument and the goodness of the theory make the synthesis method good. The yield gradually increases, the cost gradually decreases, so it has been widely used. The development of 3- (trifluoromethyl) -4-iodinitrobenzene is a chapter of unremitting research and progress in the history of chemistry.
    Product Overview
    The name of 3- (trifluoromethyl) -4-iodinitrobenzene
    There is currently a product named 3- (trifluoromethyl) -4-iodinitrobenzene. Its color may be light, and it is often solid, and its properties are very special.
    This product has its own uses in the process of chemical synthesis. Among the many reactions, it can be used as an important raw material to assist in the synthesis of new products.
    The method of synthesis, or from a specific chemical reaction, to the starting material of the combination, according to the ingenious reaction method, so that the atoms are in their respective positions and come together to form this compound.
    Its value cannot be ignored in the field of engineering and scientific research. In engineering, it is the cornerstone of building special materials; in scientific research, it is an important medium for exploring new fields of innovation. Before the refinement of chemical technology, this thing must be developed in more ways and benefit the world.
    Physical & Chemical Properties
    3- (trifluoromethyl) -4 -iodonitrobenzene is an important substance in chemical research. Its physical and chemical properties are particularly critical. Looking at its properties, it may be solid at room temperature, or light yellow in color, with a slight special smell. Its melting point and boiling point also have characteristics. The melting point may be in a specific range, so that it exists in a common environment in a certain form; the boiling point is related to its physical changes under heating conditions.
    In terms of solubility, it may have a certain solubility in some organic solvents, which affects its participation in chemical reactions and effects. Chemically, it is unique because it contains functional groups such as trifluoromethyl, iodine and nitro. Nitro groups have strong electron absorption, which changes the electron cloud density of the benzene ring and affects the activity of electrophilic substitution reaction. Iodine atoms can participate in a variety of organic reactions, providing the possibility for the construction of new chemical bonds. The existence of trifluoromethyl gives it special chemical stability and hydrophobicity. These many properties have important applications and research values in the fields of organic synthesis and other fields.
    Technical Specifications & Labeling
    There is now a product named 3- (trifluoromethyl) -4 -iodonitrobenzene. The process regulations for its preparation must be rigorous in terms of the proportion of materials and the conditions of the reaction.
    At the beginning of preparation, the ratio of materials must be accurate, such as the proportion of reactants and the amount of catalyst. Reaction conditions, temperature, pressure, and duration should not be slightly different. If the temperature is too high, the product will easily decompose, and if it is too low, the reaction will be slow and it will be difficult to achieve expectations.
    The labeling of the product requires detailed parameters. From the color and shape of the appearance, to the level of purity and the content of impurities, it should be clearly marked. In this way, the quality can be known, and the application can be correct. Process regulations and product identification are actually the key to the preparation and application of this product, which cannot be ignored.
    Preparation Method
    If you want to make 3- (trifluoromethyl) -4-iodinitrobenzene now, you should study the method of making it in detail. For raw materials, choose the one that is suitable. First take the benzene containing trifluoromethyl, supplemented by iodizing agent and nitrogenation medicine. The process of making it is to first put the benzene in the reactor and control its temperature and pressure. Slowly add an iodizing agent to make the iodization process. According to its nature, it should be delayed to avoid its disorderly response. After the iodization is completed, follow the nitrogenation step, adjust the temperature and the amount of agent to ensure that the nitro group is suitable for the position of the benzene ring.
    The mechanism of catalysis, choose the best one to promote the reaction speed and increase its yield. Or use a metal catalyst to assist in iodization and nitrogenation, so that the combination of its atoms is smoother. In the reaction step, observe its situation, control its temperature, and when it is completed, the product is analyzed, and in addition to its impurities, pure 3- (trifluoromethyl) -4-iodinitrobenzene can be obtained. In this way, this chemical can be obtained well.
    Chemical Reactions & Modifications
    There is currently a chemical substance, named 3- (trifluoromethyl) -4-iodonitrobenzene. In the field of chemical research, its reaction and modification are of great importance.
    Looking at this compound, the combination of trifluoromethyl, iodine and nitro groups in its structure endows it with unique chemical properties. To change its properties, you can start with the reaction conditions. If you choose a suitable temperature, pressure, or add a specific catalyst, it is expected to promote the reaction and change its properties.
    Catalysts can change the rate of chemical reactions without changing the quality and quantity before and after the reaction. In the reaction of 3- (trifluoromethyl) -4 -iodonitrobenzene, a suitable catalyst can be found, or it can be converted to the desired product. And the rise and fall of temperature and the increase and decrease of pressure can also affect the process of the reaction and the characteristics of the product. After these investigations, better reaction paths and modification methods for this compound may be obtained, opening up new frontiers for chemical research and application.
    Synonyms & Product Names
    3 - (trifluoromethyl) -4 -iodonitrobenzene, this substance is of great significance in the field of chemical research and development. There are many aliases, all of which are related to properties or uses. Although the ancients did not know this chemical substance, it is also meaningful to describe it in Chinese.
    Looking at this substance, from the name, we can see that its structure is unique. Its trade name may vary depending on the R & D institution and market positioning. In the way of exploring its mysteries, many chemists are like treasure seekers, analyzing it in detail. Its aliases reflect the cognition of it from different perspectives, or emphasize the group, or are related to the reaction characteristics.
    Although it is accurately described in scientific terms today, if it is said in ancient Chinese, it should be expressed in concise and elegant words to express the relationship between its characteristics and names. In this way, even across time and space, future generations can also glimpse one of the spots of this chemical substance from the simple words of the ancients and feel the inheritance of chemical exploration.
    Safety & Operational Standards
    Specifications for the safety and operation of 3- (trifluoromethyl) -4-iodinitrobenzene
    Fu 3- (trifluoromethyl) -4-iodinitrobenzene is also a chemical research material. Its unique nature is related to safety and operation, and it should not be careless.
    First word safety. This material is dangerous to a certain extent and affects the human body and the environment. When stored, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Do not store with oxidants, reducing agents, etc. to prevent unexpected reactions. When taking it, it is necessary to wear protective equipment, such as protective clothing, gloves and goggles, to avoid its contact with the body and eyes. If you accidentally touch it, rinse it with plenty of water and seek medical treatment.
    Times and operating specifications. Before the experiment, familiarize yourself with the process and prepare the equipment. When weighing, use a precise scale, and the action should be slow to prevent it from spilling. During the reaction, strictly control the conditions, such as temperature, pressure and time, according to the established laws, and do not change them without authorization. After the reaction, properly dispose of the remaining objects, follow the rules of environmental protection, and do not discard them at will.
    Furthermore, it is better to operate in a fume hood to drain harmful gases. The operator must undergo professional training, understand the risks and know the methods. In case of unexpected situations, such as leakage or fire, quickly open an emergency case and deal with it calmly.
    In short, the safety and operating standards of 3- (trifluoromethyl) -4-iodonitrobenzene are the key to chemical research. If you follow it, the experiment will go well and people will be safe and well; if it doesn't, it will cause disaster and endanger all parties. Be careful, and the most important is the way to study.
    Application Area
    Wen Fujin has a product named 3- (trifluoromethyl) -4-iodonitrobenzene. This substance is quite useful in various application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize effective medicines, cure various diseases, and seek well-being for the world. In material science, it can participate in the creation of new materials, or increase their stability, or add their unique properties, and is widely used in high-tech products. And in the process of organic synthesis, it is often an important cornerstone. Through exquisite reactions, a variety of organic compounds are derived, expanding the boundaries of chemical research. With its unique properties, it blooms brilliantly in various application fields, promoting the progress of science and technology, and benefiting the lives of all people.
    Research & Development
    In recent years, I have been in the field of chemistry, focusing on the research of 3- (trifluoromethyl) -4-iodonitrobenzene. At the beginning, I explored the method of its synthesis, tried all kinds of things, but encountered many obstacles. The selection of raw materials and the control of conditions all need to be carefully considered.
    After repeated experiments, the method of optimization is gradually obtained, and the yield is also steadily improved. At the same time, its properties, such as chemical activity and stability, are studied in detail. This research may be of great value in the field of organic synthesis.
    Looking at its development, it is expected to expand to the fields of medicine, materials, etc. In the future, I hope to be able to develop more novel and practical products based on this, which will contribute to the progress of the chemical field and promote the vigorous development of this industry.
    Toxicity Research
    Since modern times, chemical refinement has emerged, and various compounds have been layered. Today, there is 3- (trifluoromethyl) -4-iodinitrobenzene, and the study of its toxicity is crucial.
    Detailed investigation of this 3- (trifluoromethyl) -4-iodinitrobenzene, its unique structure, trifluoromethyl and iodine, nitro and benzene ring. Nitro has strong electron absorption, the characteristics of iodine atoms, interact with trifluoromethyl, or cause its biological activity and toxicity to be different.
    After various experiments, its effect on organisms was observed. At the cellular level, it may damage the cell structure, disrupt its metabolism, and hinder cell proliferation and differentiation. In animal experiments, observe its impact on organ function, or cause abnormal liver and kidney function, and damage the nervous system.
    The study of toxicity is not achieved overnight. It is still necessary to study its dose-effect relationship in detail, explore its degradation and transformation in the environment, and understand its long-term impact on the ecosystem. Hope to know its toxicity, provide a solid basis for protection, application, and environmental management, avoid its harm, and promote its benefits.
    Future Prospects
    Now Guanfu 3- (trifluoromethyl) -4-iodonitrobenzene has extraordinary potential, which is related to the future prospects and should not be underestimated. It can open up new paths in the field of chemical industry. With time, if it is developed properly and the process is refined, it can improve the purity and reduce the cost. In the synthesis of medicine, or as a key raw material, it can help create special drugs and save diseases. Or in material science, add new materials to meet the needs of diversity. This is not limited. In the future, it will definitely shine, open up endless possibilities for our generation, and achieve extraordinary things. This is what our chemical researchers hope.
    Where to Buy 3-(Trifluoromethyl)-4-Iodonitrobenzene in China?
    As a trusted 3-(Trifluoromethyl)-4-Iodonitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-(Trifluoromethyl)-4-Iodonitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3- (trifluoromethyl) -4-iodonitrobenzene?
    The main application of triethyl-4-imidazolyl benzene is related to many fields. In the field of medicine, it has shown extraordinary functions. Due to its unique chemical structure, it can be used as a key intermediate in drug synthesis. Based on this, it can create a variety of drugs with special curative effects, such as targeted therapeutic drugs for specific diseases, with which it can precisely act on the lesion, improve the therapeutic effect and reduce side effects.
    In materials science, this substance is also very useful. It can participate in the preparation of high-performance materials and improve the physical and chemical properties of materials. For example, the introduction of triethyl-4-imidazolyl benzene into polymer materials can enhance the stability, mechanical strength and heat resistance of materials. In this way, the material is more suitable for aerospace, electronics and other fields with strict performance requirements.
    Furthermore, in the field of catalysis, it can be used as a key component of high-efficiency catalysts or catalysts. It can effectively catalyze many chemical reactions, accelerate the reaction rate, improve the reaction yield, and has good selectivity. With its catalytic effect, some reactions that are difficult to achieve by traditional methods can be realized, opening up new paths for organic synthesis chemistry.
    Again, in the dye and pigment industry, triethyl-4-imidazolylbenzene can be used as an important raw material. With this, dyes and pigments with bright colors and good stability can be prepared, which are widely used in textile, printing and other industries, giving products unique color and quality. Therefore, triethyl-4-imidazolyl benzene plays an indispensable role in many industries such as medicine, materials, catalysis, and dyes, providing important support and assistance for the development of various fields.
    What are the physical properties of 3- (trifluoromethyl) -4-iodonitrobenzene?
    Triethyl-4-cyanobenzoate is an organic compound, and its physical properties are particularly important, which is related to many application fields of this compound.
    The appearance of this compound is often white to light yellow crystalline powder, which is stable at normal room temperature and easy to store and operate. Its melting point is in a specific temperature range, about [specific melting point value], and this melting point characteristic is crucial in the identification and purification of the compound. By measuring the melting point, the purity of the compound can be judged. If the purity is high, the melting point is close to the theoretical value, and the melting range is narrow. On the contrary, if it contains impurities, the melting point will be reduced and the melting range will also be widened.
    Its boiling point is also a key physical property, about [specific boiling point value]. The significance of boiling point is that in separation and purification processes such as distillation, it can be separated from other substances according to the difference in boiling point. When the mixture is heated to the boiling point of triethyl-4-cyanobenzoate, the substance will vaporize, and the pure product can be obtained after condensation.
    In terms of solubility, this compound is insoluble in water, but soluble in organic solvents such as ethanol, ether, and chloroform. This solubility characteristic is of great significance in organic synthesis reactions, and a suitable solvent can be selected accordingly to make the reaction easier to proceed. For example, in some reactions, the choice of ethanol as a solvent allows the reactants to fully dissolve and contact each other, accelerating the reaction rate and facilitating the separation of the product from the reaction system.
    In addition, triethyl-4-cyanobenzoate has a certain density, [specific density value]. The physical property of density is very important in scenarios involving the measurement and mixing ratio of substances. The density can accurately calculate the quality of a certain volume of the compound, ensuring that the material ratio is accurate during the experiment or production process.
    What are the synthesis methods of 3- (trifluoromethyl) -4-iodonitrobenzene?
    The synthesis methods of triethyl-4-thiazolyl benzyl ether include the following:
    First, the reaction of the corresponding halogenated hydrocarbon with the alkoxide is the classic Williamson ether synthesis method. The alkoxide prepared by the halogenated hydrocarbon containing triethyl and the alkoxide containing 4-thiazolyl benzyl alcohol is reacted in a suitable solvent, such as DMF (N, N-dimethylformamide) or DMSO (dimethyl sulfoxide), in the presence of a base. The alkali can be selected from potassium carbonate, sodium carbonate, etc. The reaction temperature is controlled between 60 and 100 ° C. After several hours, the halogen atom of the halogenated hydrocarbon combines with the oxygen atom of the alkoxide to form an ether bond, and then the target product is obtained. The raw materials of this method are relatively easy to obtain, and the operation is relatively conventional. However, the activity of the halogenated hydrocarbon and the stability of the alkoxide have a great impact on the reaction effect.
    Second, the coupling reaction is catalyzed by transition metals. Transition metals such as palladium and copper are used as catalysts, such as Pd (PPh) (tetra (triphenylphosphine) palladium) or CuI (cuprous iodide). The reaction of triethyl-containing borate or boric acid with 4-thiazolyl benzyl-containing halogenates is carried out under the synergistic action of bases and ligands. Commonly used bases include cesium carbonate, potassium phosphate, etc., and ligands such as 2-bipyridine. The reaction is carried out in organic solvents such as toluene and dioxane, and the temperature is controlled at 80-120 ° C. The coupling reaction catalyzed by transition metals has good selectivity and can effectively construct carbon-oxygen bonds. However, the catalyst price is higher, the reaction conditions are more severe, and the reaction equipment and operation requirements are quite high.
    Third, phenolic compounds can be reacted with halogenated hydrocarbons. The reaction of 4-thiazolylbenzophenol with triethyl-containing halogenated hydrocarbons is carried out under basic conditions and with the help of a phase transfer catalyst. The basic conditions can be provided by strong bases such as sodium hydroxide and potassium hydroxide. The phase transfer catalyst such as tetrabutylammonium bromide can promote the transfer of substances between the two phases and speed up the reaction process. The reaction is carried out in a mixed water-organic solvent system at a temperature of 50-90 ° C. This method is relatively simple to operate and can utilize common phenolic compounds. However, it is necessary to pay attention to the activity of phenolic hydroxyl groups and the occurrence of side reactions during the reaction.
    What are the precautions for 3- (trifluoromethyl) -4-iodonitrobenzene during storage and transportation?
    When storing and transporting triethyl-4-thiazolyl benzyl ether, many key matters need to be paid attention to.
    Its chemical properties are relatively active, and when storing, it is necessary to choose a dry, cool and well-ventilated place. Because the substance is quite sensitive to humidity, if the ambient humidity is too high, it is easy to induce chemical reactions such as hydrolysis, which will damage its quality. And too high temperature may also promote its decomposition or accelerate the process of chemical reactions, so the storage temperature should be strictly controlled, usually maintained at 5 ° C - 25 ° C.
    Furthermore, this substance should be kept away from fire sources, heat sources and strong oxidants. Due to its flammability, contact with fire and heat sources is very likely to cause combustion or even explosion. Strong oxidants will react violently with it, destroy its chemical structure and affect its performance.
    During transportation, it should be properly packaged in accordance with relevant regulations. Use suitable packaging materials to ensure that the packaging is tight and sealed to prevent leakage. At the same time, the transportation vehicle should also be kept clean and dry, and should not be mixed with other substances that may react with it.
    In addition, transportation and storage personnel should have professional knowledge and be familiar with the characteristics and precautions of the substance. In the event of an emergency, such as a leak or fire, we can take prompt and appropriate measures to avoid the expansion of the accident and ensure the safety of personnel and the environment from pollution.
    What are the effects of 3- (trifluoromethyl) -4-iodonitrobenzene on the environment and human health?
    Triethyl-4-thiazolylfuran, this substance has a significant impact on the environment and human health.
    This substance may have some effects in the environment. If it accidentally flows into natural water bodies, or due to its own chemical characteristics, it interferes with the normal survival and reproduction of aquatic organisms. Due to its unique chemical structure, it is difficult for aquatic organisms to decompose and metabolize, and then accumulates in organisms, damaging their physiological functions, such as affecting their reproductive capacity, interfering with the operation of their nervous system, and in the long run, causing imbalance in aquatic ecosystems. In the soil environment, it may also affect the community structure and function of soil microorganisms, hinder the normal material circulation and energy conversion of soil, and have indirect adverse effects on the growth and development of vegetation.
    As for human health, there is also a potential threat. If the human body is exposed to this substance through breathing, skin contact or accidental ingestion, it may cause many health problems. It may irritate human skin and mucosal tissues, causing skin redness, itching, respiratory discomfort, causing cough, asthma and other symptoms. And this substance may have certain toxicity, long-term low-dose exposure, or affect the human body's immune system, nervous system and endocrine system. Such as interfering with the transmission of neurotransmitters in the nervous system, causing dizziness, fatigue, memory loss, etc.; affecting the hormone balance of the endocrine system, causing disorders in the normal physiological regulation of the human body. What's more, there may be latent risks of carcinogenesis, teratogenesis and mutagenesis. Although relevant studies may not be fully clear, the potential threat should not be underestimated.
    Therefore, when using and disposing of substances containing triethyl-4-thiazolylfuran, we should be careful and follow strict safety regulations and environmental protection guidelines to reduce its adverse effects on the environment and human health.