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3-Trifluoromethoxybenzenesulfonyl Chloride

3-Trifluoromethoxybenzenesulfonyl Chloride

Hongda Chemical

Specifications

HS Code

515319

Chemical Formula C7H4ClF3O4S
Molecular Weight 276.62
Appearance Colorless to light yellow liquid
Boiling Point 105 - 107°C (12 mmHg)
Melting Point N/A
Density 1.61 g/cm³
Solubility Reacts with water, soluble in organic solvents like dichloromethane
Flash Point 113.7°C
Purity Typically high - purity (e.g., 97%+)
Stability Stable under normal storage conditions, but reacts with moisture, strong bases

As an accredited 3-Trifluoromethoxybenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - trifluoromethoxybenzenesulfonyl chloride in a sealed, corrosion - resistant bottle.
Storage 3 - Trifluoromethoxybenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It must be kept in a tightly - sealed container to prevent contact with moisture, as it can react with water. Store it separately from incompatible substances like bases and reducing agents to avoid potential hazardous reactions.
Shipping 3 - Trifluoromethoxybenzenesulfonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using appropriate containers to prevent leakage, and labeled clearly to indicate its dangerous nature.
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3-Trifluoromethoxybenzenesulfonyl Chloride 3-Trifluoromethoxybenzenesulfonyl Chloride
General Information
Historical Development
3-Trifluoromethoxybenzenesulfonyl chloride is also a chemical product. At the outset, chemists studied in the laboratory and first obtained this compound. At that time, it was only an academic inquiry, aiming to clarify its chemical characteristics.
With the passage of time and the advance of science and technology, everyone gradually realized the wonderful use of this product in organic synthesis. It can be used as a key reagent to participate in various organic reactions and help create new compounds.
With the prosperity of industry, the demand for it is increasing. The chemical industry seeks ways to scale up production, optimize processes, and improve yield and purity. So far, 3-trifluoromethoxybenzenesulfonyl chloride has come out of the laboratory and emerged in the chemical industry. It has made contributions to the pharmaceutical, materials and other industries, contributing to the development of modern chemistry.
Product Overview
Today there is a substance called 3 - Trifluoromethoxybenzenesulfonyl Chloride. This is a chemical substance with unique properties. Looking at its structure, it contains a group of trifluoromethoxy and benzenesulfonyl chloride. It is pure and uniform in color, either liquid or crystalline, depending on the temperature and pressure around it.
This substance is widely used in the field of organic synthesis. It can be used as a reagent to participate in many reactions, such as meeting with alcohols, which can produce sulfonate compounds; when it comes into contact with amines, it forms a sulfonamide product. Its reactivity is quite high, and it is often a key element in the synthesis of specific structural organic compounds. And in the pharmaceutical, pesticide and other industries, it is also of great value, helping to create novel drugs and efficient pesticides, which contribute to improving human well-being and protecting crop growth.
Physical & Chemical Properties
3-Trifluoromethoxybenzenesulfonyl chloride has unique properties and different qualities. In the field of chemistry, its physical and chemical properties are crucial. Looking at its shape, at room temperature, or as a clear liquid, it has a specific color state. Its boiling point and melting point are all physical parameters to characterize its characteristics. The boiling point is related to the temperature of its gasification, and the melting point shows the degree of solid-liquid transformation.
When it comes to chemical properties, its sulfonyl chloride group is quite active. It is easy to hydrolyze in contact with water, resulting in corresponding acids and hydrogen chloride. This hydrolysis makes storage and use need to be careful. And its fluorinated structure endows it with unique chemical stability and reactivity. It can be a powerful reagent in the process of organic synthesis, and can introduce specific functional groups to form a variety of organic compounds. It has potential uses in the fields of medicine and materials.
Technical Specifications & Labeling
Today there is a product called 3 - Trifluoromethoxybenzenesulfonyl Chloride. It is quite useful in the field of industry and scientific research. When it comes to the technical specifications and labels (product parameters) of this substance, it should be carefully examined.
Technical specifications are related to the purity and composition of this substance. The purity must reach the highest standard, and the impurity content must be minimal to be practical. The proportion of ingredients should also be accurate to ensure the stability of its chemical properties.
For the identification (product parameters), its physical properties, such as color, shape, smell, etc. It is also necessary to mark its chemical properties, such as melting point, boiling point, flash point and other key parameters. This is an important basis for users to judge and apply this object, and they should not make any mistakes in order to make the best use of it and play a good role in various fields.
Preparation Method
For 3-trifluoromethoxy benzene sulfonyl chloride, the preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism, which is quite important. The selection of raw materials, when carefully selected, based on high-quality benzene compounds, is the starting point. In the production process, temperature control and pressure control are the keys. In the first step, a specific group is introduced into the benzene ring, and through fine reaction steps, precise operation is achieved to achieve the desired structure. In the reaction step, each link is connected in an orderly manner and carried out according to a specific timing, so as not to cause disorder. In terms of catalytic mechanism, choose the appropriate catalyst to accelerate the reaction, increase efficiency and yield. In this way, high-quality 3-trifluoromethoxybenzene sulfonyl chloride products can be obtained, which can be used in the chemical industry.
Chemical Reactions & Modifications
I tried to study 3 - Trifluoromethoxybenzenesulfonyl Chloride. Its transformation is related to the change of effectiveness and quality. In the past, it was studied, and there were some defects in its transformation, the yield was not extremely good, and the quality also needed to be adjusted.
Then think about changes and improve, and explore in detail the conditions of the transformation. Try to change the amount of catalyst at different temperatures and pressures, and change the amount of catalyst to observe its corresponding state. After repeated tests, it is obtained that the temperature and pressure are appropriate, and the amount of catalyst is appropriate, and the yield of the transformation is significantly increased.
As for the quality, after changing the method, the purity of the product is also increased, and the impurities are less. In this way, the transformation of 3-Trifluoromethoxybenzenesulfonyl Chloride should be good, and the quality should also be advanced, which can be used for a wide range of good materials.
Synonyms & Product Names
3-Trifluoromethoxybenzenesulfonyl Chloride, the chemical product also has the same trade name in the industry.
The same name of this product, or the name of its chemical manufacture. Because it contains trifluoromethoxy (trifluoromethoxy) and benzenesulfonyl chloride (benzenesulfonyl chloride), it may have the name of a combination of the two.
As for the trade name, the name of each company, or its characteristics, or it is convenient for the market. However, the same or trade name refers to the specific chemical product, its properties, uses, etc., which are based on the origin of 3-Trifluoromethoxybenzenesulfonyl Chloride. In chemical research and industrial use, it is essential to identify the same trade name, which is essential to ensure communication and operation.
Safety & Operational Standards
"Specifications for the Safety and Operation of 3-Trifluoromethoxybenzene Sulfonyl Chloride"
For 3-trifluoromethoxybenzene sulfonyl chloride, it is also a chemical substance. Its nature is special, and strict regulations must be followed during operation to ensure safety.
First words storage. This item should be placed in a cool, dry and well-ventilated place. Avoid water and fire, and keep away from heat sources to prevent accidents. The device must be tightly sealed and do not allow air leakage. If stored improperly, it may cause qualitative change or risk.
As for the operation, be careful. Operators should be in front of protective equipment, such as protective clothing, gloves, goggles, etc. Do it in the fume hood so that the exhaust gas can be discharged quickly without touching the human body. When operating, do not contact the skin, eyes and eyes. If you accidentally touch it, rinse it with a lot of water quickly and seek medical attention immediately.
When mixing and blending, add it in sequence, slowly, observe its changes, and do not cause sudden violence. When heating, control its temperature, step by step, to prevent explosion and boil. After use, clean the appliance and do not leave residue.
Furthermore, emergency measures should not be ignored. Prepare fire extinguishers to know the reason for leakage. If there is a leak, quickly stop the source, surround the scene, and ventilate. Small leaks should be sucked up with vermiculite, etc., and large leaks should be disposed of according to regulations. Report to the relevant and discuss countermeasures.
In short, although 3-trifluoromethoxybenzenesulfonyl chloride is needed for scientific research and production, safety is more important than Mount Tai. By following this specification, the operation can be guaranteed and the scientific research and production are smooth.
Application Area
3-Trifluoromethoxybenzenesulfonyl chloride is one of the chemical products. Its application field is quite wide. In the field of medicinal chemistry, it is often the key raw material for the synthesis of special drugs, which can help create compounds with unique pharmacological activities to treat various diseases. In material science, it can improve the properties of materials, such as enhancing their corrosion resistance and enhancing surface activity. It is also used in fine chemical synthesis, through exquisite reaction paths, to prepare a variety of high-value-added fine chemicals. With its special chemical structure, it shows extraordinary potential in many fields, providing new opportunities for the development of related industries and promoting the progress of science and technology and industry.
Research & Development
I am committed to the research of 3-Trifluoromethoxybenzenesulfonyl Chloride. This compound has unique properties and has great potential in the field of organic synthesis. At the beginning, I explored the method of its preparation. After repeated experiments, I prepared various raw material proportions, controlled temperature and duration, and tried to obtain a pure product. Although the process was difficult, it failed from time to time, but I was never discouraged.
Then, study its reaction characteristics, interact with various reagents, and investigate the reaction mechanism in detail. It was found that under specific conditions, it can efficiently combine with a variety of functional groups, providing an opportunity to create novel organic molecular structures.
Looking at it now, the results of this research are gradually emerging, and it is expected to show great potential in the fields of medicine and materials. In the future, we will deepen our exploration and expand its application boundaries, with the hope of contributing to the academic community and industry and promoting the development of this field.
Toxicity Research
Taste the chemical industry, there is a name 3 - Trifluoromethoxybenzenesulfonyl Chloride, its strong nature, in the study of toxicology, is very important.
This thing is highly corrosive and toxic. When entering the body, it will damage the organs, hinder the luck of qi and blood, and disrupt the balance of yin and yang. When the skin touches it, it will burn, red and swollen, and even rot. If inhaled through the mouth and nose, the lungs and organs will be invaded, coughing and wheezing, chest tightness, shortness of breath will not rest.
Therefore, when studying its toxicity, it is necessary to be cautious and careful. In the secret room, preventive equipment is set up, and the operators are strictly equipped with protective gear to avoid its harm. Detailed observation of its in different doses, ways, the impact on the living, recording its symptoms changes, analysis of its toxicology.
stage can be clear of its toxicity regulations, in order to use this material, establish safety rules, to protect people's health, protect the safety of the material, so that the chemical industry, prosperous but harmless, Lize for a long time.
Future Prospects
Today there is a product called "3 - Trifluoromethoxybenzenesulfonyl Chloride", which has great potential in the field of chemical industry. Future development can be extended to various uses. Or for the research and development of new drugs, which can accurately target lesions and help heal diseases. It can also be used for the creation of high-end materials, giving materials specific properties, such as corrosion resistance, wear resistance, etc.
And its synthesis method is expected to improve, increase yield, and reduce costs. On the one hand of environmental protection, it is expected to achieve a better green process and reduce pollution. Scientists should strive to study and explore its endless possibilities, with the hope of using this product to benefit future generations, and open up new chemical fields, so that this substance will shine in the future, be used by the world, and become an unfinished business.
Where to Buy 3-Trifluoromethoxybenzenesulfonyl Chloride in China?
As a trusted 3-Trifluoromethoxybenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Trifluoromethoxybenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-trifluoromethoxybenzenesulfonyl chloride?
Trichloroacetoxyphenylboronic anhydride, which is a crucial reagent in organic synthesis, has a wide range of uses.
First, in the field of medicinal chemistry, it is a key synthesis intermediate. The construction of many drug molecules often relies on its participation in reactions. For example, the synthesis of certain compounds with specific biological activities, through its unique chemical structure and reactivity, can achieve precise molecular construction, helping to create drugs with excellent efficacy and small side effects. When developing drugs for the treatment of cardiovascular diseases, nervous system diseases, etc., trichloroacetoxyphenylboronic anhydride can ingeniously introduce specific functional groups, optimize the properties of drug molecules, enhance the ability of drugs to bind to targets, and enhance drug efficacy.
Second, in the field of materials science, it also has significant uses. In the preparation of high-performance organic optoelectronic materials, it can participate in polymerization reactions, giving the material special electrical and optical properties. For example, the preparation of organic Light Emitting Diode (OLED) materials can regulate the conjugate structure of the material, improve the luminous efficiency and stability of the material, so that the OLED display shows more brilliant colors and higher resolution.
Third, it is a commonly used reagent in the methodological research of organic synthetic chemistry. Chemists use it to develop novel reaction pathways and methods to expand the means of organic synthesis. It can participate in the formation of carbon-carbon bonds and carbon-heteroatomic bonds, providing a novel strategy for the synthesis of complex organic molecules and promoting the development of organic synthetic chemistry. In the total synthesis of many complex natural products, trichloroacetoxyphenylboronic anhydride plays an indispensable role, enabling chemists to successfully construct complex molecular structures.
What are the physical properties of 3-trifluoromethoxybenzenesulfonyl chloride?
Triethoxysilane is a colorless and transparent liquid with an ether odor. Its density is about 0.93g/cm ³, which is lighter than water and can float on water. The boiling point is 134 ° C, at which temperature it will change from liquid to gaseous state. The melting point is -70 ° C. Below this temperature, it condenses into a solid state.
It is soluble in a variety of organic solvents. Common organic solvents such as ethanol and ether can be miscible with it. This property is due to the interaction between its molecular structure and organic solvent molecules. However, triethoxysilane reacts with water to form ethyl silicate and ethanol, and this hydrolysis reaction makes it difficult to exist stably in water.
In terms of chemical activity, the ethoxy group in triethoxysilane is more active and easy to condensate with hydroxyl-containing substances. For example, when it encounters a polymer with hydroxyl groups, the ethoxy group will combine with the hydroxyl group, remove ethanol, and then realize the connection with the polymer, so that it can be used to modify the surface of the polymer material. In the field of organic synthesis, it is often used as a silicon source to introduce silicon atoms into the reaction system and participate in the construction of silicon-containing compounds.
Because of its strong volatility, it will evaporate quickly in the air. When using it, it is necessary to pay attention to the ventilation of the operating environment to avoid the accumulation of steam. And the substance is flammable. In case of open flames and hot topics, there is a risk of fire. When storing and using, it must be kept away from fire and heat sources for safety.
What are the chemical properties of 3-trifluoromethoxybenzenesulfonyl chloride?
Triethoxy silane nitrile chloride is a family of organosilicon compounds. It is active and has a wide range of uses in organic synthesis, materials science and other fields.
This substance has hydrolysis properties. When exposed to water, the ethoxy group can be gradually replaced by the hydroxyl group to produce silanol, which is released with ethanol. The hydrolysis process is easily catalyzed by acid and base, which accelerates the reaction. This hydrolysis property is often used in the preparation of silica sol or siloxane polymer. By controlling the hydrolysis conditions, the structure and properties of the product can be regulated.
Triethoxy silane nitrile chloride can participate in the polycondensation reaction. The hydrolyzed silanol can be condensed with other siloxides or compounds with active groups to form silicon-oxygen bonds (Si-O-Si), and then a polymer network can be constructed. By selecting different reactants and reaction conditions, silicone polymers with specific structures and functions can be prepared for use in coatings, adhesives, sealants and other materials.
Because of its nitrile group, triethoxysilanitrile chloride can participate in nitrile-related reactions. Nitrile groups can be hydrolyzed to carboxyl groups or reduced to amine groups, thereby introducing new functional groups and expanding the application scope of compounds. For example, after hydrolysis to form carboxyl groups, they can react with compounds containing hydroxyl groups and amine groups to build more complex molecular structures.
In the nucleophilic substitution reaction, the chlorine atom of triethoxysilane nitrile chloride has high activity and is easily replaced by nucleophilic reagents. Nucleophilic reagents such as alcohols and amines can replace chlorine atoms to form new organosilicon compounds. This reaction is of great significance in the construction of organosilicon derivatives and the surface modification of materials.
In short, the unique chemical properties of triethoxysilane nitrile chloride are of great value in the field of organic synthesis and material preparation. By skillfully using its reaction characteristics, many compounds and materials with special properties can be prepared.
What is the preparation method of 3-trifluoromethoxybenzenesulfonyl chloride?
To make triethoxysilane chlorine, you can follow the ancient method. First take silicon powder and hydrogen chloride gas, use copper as a catalyst, and heat together at high temperature. Its shape is as follows: the silicon powder is placed in a special device, tightly sealed, through hydrogen chloride gas, dispersed with copper powder, and heated to hundreds of degrees Celsius. At this time, the silicon and hydrogen chloride gas phase reaction, silicon atoms combine with chlorine atoms, hydrogen atoms escape to form trichlorosilane, the formula is $Si + 3HCl\ stackrel {high temperature, Cu }{=\!=\!=} SiHCl_3 + H_2 $.
The resulting trichlorosilane reacts with absolute ethanol. The trichlorosilane is slowly poured into a container containing anhydrous ethanol and carried out under low temperature and stirring. The hydroxyl group of ethanol is replaced by the chlorine atom of trichlorosilane, and the hydrogen of ethanol and chlorine form hydrogen chloride to escape, so triethoxysilane chloride is obtained. The formula is $SiHCl_3 + 3C_2H_5OH\ longrightarrow Si (OC_2H_5) _3Cl + 3HCl $.
After the reaction is completed, the product may contain impurities and must be purified by distillation and distillation. The mixture is placed in a still, and the temperature is controlled within a specific range. According to the difference in boiling point, the triethoxysilane chloride is vaporized first, and then condensed to obtain a pure product. In this way, high-purity triethoxysilane chloride can be obtained. Throughout the process, attention should be paid to the control of temperature, material ratio and reaction environment in order to achieve optimum yield and purity.
What are the precautions for the storage and transportation of 3-trifluoromethoxybenzenesulfonyl chloride?
Trichloroacetoxybenzarsonic acid is a highly toxic drug, and its storage and transportation need to be extremely cautious.
When storing, one must choose a cool, dry and well-ventilated place. Because if the drug is placed in a humid and warm place, it may cause chemical properties to change and cause danger. Second, it needs to be stored in isolation from acids, alkalis, oxidants, etc. This is because its chemical properties are active, and contact with them can easily cause violent chemical reactions, or cause explosions, leaks and other disasters. Third, the storage container must be strong and well sealed. Corrosion-resistant materials such as glass and ceramics are appropriate, and the warning words "highly toxic" must be clearly marked on the outside of the container to prevent accidental touch and misuse.
As for transportation, first of all, transportation personnel must have professional training and be familiar with the characteristics of trichloroacetoxybenzarsonic acid and emergency treatment methods. Transportation vehicles also need to ensure that they are in good condition and have corresponding protective and emergency equipment. Secondly, during transportation, avoid high temperatures, sun exposure and bumps. High temperatures may accelerate the decomposition of drugs, and bumps may cause damage to the container. Furthermore, strictly abide by relevant transportation regulations, drive according to the designated route, and the transportation process needs to be closely supervised by special personnel. Once any abnormalities are detected, they should be properly disposed of immediately. The opportunity must not be delayed, so as not to endanger people's lives and environmental safety.