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3-(Trifluoromethoxy)Fluorobenzene

3-(Trifluoromethoxy)Fluorobenzene

Hongda Chemical

Specifications

HS Code

218973

Chemical Formula C7H4F4O
Molecular Weight 180.1
Appearance Colorless liquid
Boiling Point 106 - 107 °C
Density 1.378 g/cm³
Flash Point 16 °C
Solubility Insoluble in water, soluble in organic solvents
Refractive Index 1.396

As an accredited 3-(Trifluoromethoxy)Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 mL bottle of 3-(trifluoromethoxy)fluorobenzene, well - sealed for chemical storage.
Storage 3-(Trifluoromethoxy)fluorobenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly closed container made of suitable materials like stainless steel or glass to prevent leakage. Store separately from oxidizing agents and incompatible substances to avoid potential reactions.
Shipping 3-(Trifluoromethoxy)fluorobenzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. These containers prevent leakage, ensuring safe transit of this potentially hazardous chemical.
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3-(Trifluoromethoxy)Fluorobenzene 3-(Trifluoromethoxy)Fluorobenzene
General Information
Historical Development
3- (trifluoromethoxy) fluorobenzene is also a product of the chemical industry. In the past, many chemists studied and searched for new things to expand the field of chemical industry. At the beginning, the exploration was difficult, and everyone tried many times but failed to find a way. However, the public was not discouraged, and they tried their best and tried again and again.
After a long time of research, they finally found the way to synthesis. At the beginning, the yield was still low, but later everyone kept improving and improving the process, so that the yield gradually increased and the quality became better. Since then, 3- (trifluoromethoxy) fluorobenzene has emerged in the chemical industry, and its application has become wider and wider. It has added to many fields and become an important part of the development of the chemical industry. Its development is a testament to the wisdom and perseverance of the chemical sages.
Product Overview
Today, there is a substance called 3- (trifluoromethoxy) fluorobenzene. This substance is unique and related to chemical research, which is quite important.
Its shape and quality, color state or characteristics, and smell are also different from ordinary things. Its molecular structure is exquisite, and the trifluoromethoxy group and fluorine atom are combined on the benzene ring, which is like a natural structure. This structure gives it a different kind of chemical activity.
In the field of chemical industry, it has a wide range of uses. Or it is a key raw material for the synthesis of delicate compounds. With its unique structure, it can lead the reaction to a novel path and open up a path for the creation of new substances. It may also emerge in materials science, helping to develop new materials with specific properties, such as weathering and corrosion-resistant materials.
However, the preparation of this material also requires fine methods. It is necessary to follow chemical principles, control temperature, speed, and select adapters to obtain pure products. And its impact on the environment and the human body should also be investigated in detail to ensure the safety and stability of use.
Physical & Chemical Properties
3 - (trifluoromethoxy) fluorobenzene is an important substance in chemical research. Its physical and chemical properties are unique and related to research and application.
In terms of physical properties, this substance is often in the state of a colorless liquid, with a specific boiling point and melting point. The number of its boiling point is the key to accurately reflect the intermolecular forces, and it is also important for separation and purification. The melting point indicates the conditions for the transformation of its solid state and liquid state, and it should be paid attention to during storage and transportation.
As for chemical properties, the structure of 3 - (trifluoromethoxy) fluorobenzene gives it active reactivity. The presence of fluorine atoms and trifluoromethoxy groups allows it to participate in many organic reactions. Such as nucleophilic substitution reaction, due to the electron absorption of fluorine atoms, the electron cloud density of benzene ring changes, making it more vulnerable to nucleophilic attack. This property is very useful in the synthesis of complex organic compounds, and can build special chemical structures, providing a foundation for new drug development, materials science and other fields.
Technical Specifications & Labeling
The process specification and identification (product parameters) for the production of 3 - (trifluoromethoxy) fluorobenzene are described in detail as follows. The process specification needs to be accurately controlled for various reaction conditions. The ratio of raw materials must be accurate, the reaction temperature should be stable in a certain range, and the duration should also be appropriate, so as to ensure the purity and yield of the product.
As for the identification (product parameters), its chemical characteristics, such as melting point, boiling point, purity and other key parameters, should be stated. On the packaging, it should also be clearly marked so that the viewer can see it at a glance to ensure that the product is correct in circulation and use, and meets the high standards of process and quality.
Preparation Method
The raw materials and production process are the key to the preparation of 3 - (trifluoromethoxy) fluorobenzene. Take an appropriate amount of fluorobenzene and mix it with a reagent containing trifluoromethoxy group in a specific ratio. This is the starting material. The reaction steps are as follows: In a suitable reaction kettle, control the temperature in a certain range, stir to make the two fully contact and initiate the reaction. During this period, the temperature and reaction time need to be precisely controlled to prevent side reactions from occurring. When the reaction is gradually completed, the impurities are removed through the separation and purification process to obtain pure 3 - (trifluoromethoxy) fluorobenzene. In this process, the catalytic mechanism cannot be ignored. The use of high-efficiency catalysts can speed up the reaction rate and increase the yield. In this way, 3 - (trifluoromethoxy) fluorobenzene can be prepared, and its quality and output can be guaranteed.
Chemical Reactions & Modifications
In the field of chemistry, the product of 3 - (trifluoromethoxy) fluorobenzene is related to the reaction and modification of chemistry, which is really important in the academic community. Its reaction path is like an ancient artisan and man-made tool, which requires intensive study and ingenuity.
At first, the reaction was explored by conventional methods, but the effect was not obvious. Due to the special nature of trifluoromethoxy, the structure of fluorobenzene is also different, and the two are combined, and many factors hinder the reaction. Later, I thought about changes, and changed to a new agent to intervene, just like adding strong wind to the boat. The new agent is mild in nature, has a good affinity with the reactants, and can stabilize the intermediate, so that the reaction can flow smoothly like a canal.
As for modification, it aims to improve its performance and be widely used. After various attempts, the structure has been modified in a specific way, so that it is heat-resistant and corrosion-resistant. Just like the jade has been cut, the brilliance is fully displayed. From this point of view, the wonders of chemistry lie in the change of reaction, the ingenuity of modification, and unremitting research can achieve good results.
Synonyms & Product Names
Today there is a thing called 3- (trifluoromethoxy) fluorobenzene. This thing has a wide range of uses in the field of chemistry. There are also many different names. Although the names are different and the quality is the same, they all refer to this thing.
The intercity names vary depending on their nature or shape. However, the root cause is this 3- (trifluoromethoxy) fluorobenzene. The existence of its different names, in the industry, all know that it is the same substance.
The beauty of chemistry lies in its precision. Although multiple names coexist, its characteristics are unique. The characteristics of 3- (trifluoromethoxy) fluorobenzene determine its application in chemical, scientific research and other fields. Therefore, it is crucial for the industry to know its synonyms and trade names. Only by knowing its name can we make good use of it and contribute to scientific research and production.
Safety & Operational Standards
3 - (trifluoromethoxy) fluorobenzene is also a chemical substance. Its safe production and operation specifications, we should be cautious.
It is active and has special chemical activity. During production and preparation, the operator must wear complete protective equipment, such as corrosion-resistant clothes and gloves, and carry a gas mask to avoid contact with the skin and respiratory tract.
When storing, choose a cool, dry and well-ventilated place, away from fire and heat sources, and avoid direct sunlight. The reservoir must also be tightly closed to prevent its leakage.
During operation, precise temperature control and pressure control are essential. The reaction rate and conditions should be carried out in accordance with the norms and must not be changed without authorization. In the event of a sudden leak, an emergency case should be initiated immediately. Evacuate the surrounding crowd, and the operator should take professional protection to stop the source of the leak. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be blocked by embankments and collected and dealt with by professional equipment.
In addition, when discarding and disposing of, it must also comply with environmental protection regulations and cannot be discarded at will. This is the main rule for the safe production and operation of 3 - (trifluoromethoxy) fluorobenzene. If you follow it, you can ensure everything goes smoothly and avoid disasters.
Application Area
Today there is a thing called 3- (trifluoromethoxy) fluorobenzene, which is widely used in various fields. In the field of medicine, this compound is often a key raw material. With its characteristics, it can make a variety of special drugs, treat various diseases, and save the suffering of the common people.
In materials science, there are also extraordinary things. It can participate in the synthesis of new materials, so that the materials have specific properties, such as better weather resistance and stability. It is used in construction, electronics and many other aspects to improve the quality and lifespan of objects.
In fine chemicals, it is indispensable. It helps to produce a variety of fine chemicals, such as high-end coatings, dyes, etc., which make the products bright in color and excellent in performance. It is widely used in daily and industrial fields, adding luster to life and production.
Research & Development
I have been researching chemical products for many years, including 3- (trifluoromethoxy) fluorobenzene. At the beginning, it was difficult to obtain this product. The choice of raw materials and the degree of proportion need to be studied in detail. All kinds of attempts, or the reaction is incomplete, or there are many impurities.
However, I did not give up, and tried repeatedly. In terms of reaction conditions, temperature, pressure, catalyst, consider one by one. Finally, the method of optimization is gradually achieved. The purity of the product is improved, and the output is also increased.
Looking at this research process, although there are many difficulties, only perseverance and ingenuity can break the game. In the future, it is hoped that based on this, we will explore new paths to make this product more widely used in the chemical industry and contribute to the development of the industry.
Toxicity Research
Recent research on toxicity, specializing in the study of a substance named 3- (trifluoromethoxy) fluorobenzene. The study of the toxicity of this substance is crucial. Detailed investigation of its properties is of great use in pharmacology and the environment.
When studying the toxicity of this substance, the first thing to look at is its chemical properties. Its molecular structure is unique, and the trifluoromethoxy group coexists with the fluorine atom, or causes abnormal activity. Then to explore the change of its entry into the body, what path it follows, and what mechanism it disturbs, all need to be carefully investigated.
Review its shadow in the environment. Scattered outside, or contaminated with water and soil, harmful to life. Its degradation state is also the key. If it is difficult to decompose, it will accumulate in the ecology and cause endless harm.
The study of toxicity is not a matter of one person, but a joint effort by the academic community. It is necessary to gather the wisdom of everyone, follow the method of science, and investigate carefully in order to obtain the truth and avoid harm for the world.
Future Prospects
Although I have made some progress in my research on trifluoromethoxy fluorobenzene, I still have a long-term prospect in my mind. This substance is unique and has a wide range of applications. I am convinced that it will shine in the future.
In the future, when we deeply cultivate the synthesis method, we will strive to improve the process, make the process simpler, the yield can jump, and the cost can be reduced, so that it can be widely used in industrial production. At the application end, we will focus on exploring its potential in the field of medicine, hoping to help the creation of new drugs and contribute to the treatment of diseases and saving people. And in material science, we also hope to develop new functional materials and promote the progress of the industry.
I firmly believe that with time, trifluoromethoxy fluorobenzene can emerge in many fields and contribute to future scientific and technological development and social well-being. This is what I hope for, and it is also the unremitting pursuit of scientific research.
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Frequently Asked Questions

As a leading 3-(Trifluoromethoxy)Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3- (trifluoromethoxy) fluorobenzene?
The main use of tris (hydroxyethyl) phosphine is the principle of a single force. Its activity and activity are of great importance in the field of chemical and biological technology.
In the field of chemical synthesis, tris (hydroxyethyl) phosphine is often used to promote specific reactions. For example, it can be used for the addition of thiol-alkenyl, which can reduce carbon-sulfur emissions in an efficient and effective manner. Due to the original nature of tris (hydroxyethyl) phosphine, it can activate the alkenyl, and it is easier to generate and add thiols to synthesize various sulfur-containing compounds. This compound is widely used in many aspects such as technology, materials, etc.
In biological research, tri (hydroxyethyl) phosphine also plays an indispensable role. First, it can be used in the study of protein and nucleic acid. The function of protein is often determined by its disulfide. Tri (hydroxyethyl) phosphine can effectively reduce the original disulfide, so that the protein can be dissociated, so that the scientific family can deeply explore the various components of protein and their interactions. Second, in the operation of nucleic acids, tri (hydroxyethyl) phosphine can protect the nucleic acid from oxidation and maintain its integrity. Because it can eliminate the possible oxidation in the environment, prevent the nucleic acid group and phosphate backbone from being oxidized and broken, and ensure the profitability of the nucleic acid phase, such as PCR reaction, gene cloning, etc., it is necessary to determine the nucleic acid.
In addition, tris (hydroxyethyl) phosphine can also be used for the reaction of some gold catalysis. Its gold coordination can change the reaction of gold catalysis, and it can control the activity of the catalytic reaction, which prompts some reactions to the reaction of gold generation. The new catalytic reaction provides a powerful means. Therefore, the original properties of tris (hydroxyethyl) phosphine play an important role in many aspects of chemistry and biology.
What are the physical properties of 3- (trifluoromethoxy) fluorobenzene?
Tris (trihydroxyethyl) amine ether naphthalene, its physical rationality is as follows:
Under normal temperature, tris (trihydroxyethyl) amine ether naphthalene is mostly white to light yellow crystalline powder, its appearance is delicate, uniform texture, under light, occasionally flickering with a fine luster, which is easy to identify and use.
When it comes to the melting point, it is about [X] ° C. This temperature is well-defined and is its inherent property. Under specific heating conditions, that is, the solid state gradually melts into a liquid state. This melting point characteristic is an important parameter in many industrial processes and experimental operations. It is related to the temperature control during processing and application.
In addition to solubility, the substance is slightly soluble in water. When dissolved in water, only part of it can merge with water molecules, and the solution is slightly cloudy. However, in organic solvents such as ethanol and acetone, its solubility is quite good, and it can be quickly dispersed and dissolved to form a uniform and transparent solution. This difference in solubility provides many possibilities for its separation, purification and application in specific environments.
When it comes to density, its value is about [X] g/cm ³, indicating the amount of substance contained in a unit volume. This density characteristic makes it suitable for mixing or separation with other substances. According to the density difference, specific methods such as centrifugation and sedimentation can be used to achieve effective treatment.
As for the smell, tris (trihydroxyethyl) amine ether naphthalene has a weak special smell, which is not pungent and intolerable, but it is also clearly identifiable. Although this smell is not strong, it is also a characteristic that needs attention in production and use scenarios, which is related to the operating environment and personnel experience.
What is the production method of 3- (trifluoromethoxy) fluorobenzene?
The preparation method of tri (triethoxy) silane is as follows:
First take an appropriate amount of ethanol, place it in a clean reactor, and slowly add sodium metal. This process requires careful operation, because the reaction between sodium and ethanol is violent, hydrogen gas will be released. When the sodium is completely reacted with ethanol, a solution of sodium ethanol will be formed.
Then, trichlorosilane is dropped into the above-mentioned reaction kettle containing sodium ethanol at a suitable speed. This process requires strict control of the speed to prevent the reaction from being too rapid and out of control. Trichlorosilane and sodium ethanol will undergo a substitution reaction, in which the chlorine atom is replaced by an ethoxy group, resulting in tri (triethoxy) silane and sodium chloride.
When the reaction is going on, it is necessary to pay close attention to the change of reaction temperature and pressure. The reaction temperature can be adjusted by cooling or heating device, so that the reaction can proceed smoothly within a suitable temperature range. At the same time, it is necessary to ensure that the sealing of the reaction kettle is good to avoid the intrusion of external impurities and affect the purity of the product.
After the reaction is completed, the reaction mixture contains the generated three (triethoxy) silane, sodium chloride and the raw material that has not been fully reacted. First, the solid sodium chloride is separated by filtration operation. Then, by means of distillation, the three (triethoxy) silane is distilled from the mixture according to the difference in the boiling point of each component, so as to obtain a relatively pure three (triethoxy) silane product. During the distillation process, it is necessary to precisely control the temperature and pressure to collect fractions within a specific boiling point range to ensure the purity and quality of the product.
What should be paid attention to when storing and transporting 3- (trifluoromethoxy) fluorobenzene?
When storing and transporting tris (triethoxy) silane, many key matters need to be paid attention to.
Its nature is more active, and the storage environment requirements are strict. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it is easy to cause combustion and explosion in case of open flames and hot topics, so fireworks must be strictly prohibited in storage places. At the same time, avoid contact with oxidants, acids and other substances to prevent violent chemical reactions. Because of its active chemical properties, encounters with these substances may cause the reaction to go out of control, posing a safety hazard.
Storage containers are also crucial. Corrosion-resistant materials, such as stainless steel, special plastics, etc., need to be selected to prevent the container from being corroded and causing leakage. The seal must be good to avoid reaction with moisture, oxygen and other components in the air. Tri (triethoxy) silane is easy to hydrolyze, and will produce chemical reactions in contact with water, which will affect its quality and performance.
During transportation, follow relevant regulations on the transportation of hazardous chemicals. Use special transportation vehicles to ensure that the vehicles have good ventilation and fire protection facilities. Transportation personnel should be professionally trained and familiar with its characteristics and emergency treatment methods. When handling, it should be handled lightly. Do not collide or drag to prevent leakage caused by damage to packaging containers.
If a leak occurs during transportation, emergency measures should be taken immediately. Evacuate the surrounding people and strictly prohibit unrelated personnel from approaching. Quickly cut off the fire source to prevent the leakage from causing fire. At the same time, use suitable adsorption materials for collection and treatment to avoid the spread of leaks and pollution to the environment.
In this way, when storing and transporting tri (triethoxy) silane, strict control of all aspects can ensure safety and prevent accidents.
What are the environmental effects of 3- (trifluoromethoxy) fluorobenzene?
(Tri (hydroxy) ethyl) silicone oil is involved in a wide range of environments. Its temperature and quality are stable, but it is applied between heaven and earth, and it also has various effects.
Looking at its physical properties, this silicone oil has the property of smoothness. If it flows in water and soil, or causes changes in pores in the soil, it will make the seepage of water easier. In the water body, or form a film, blocking the exchange of air and water, causing the loss of dissolved oxygen in water, and aquatic people may suffer from it.
And because of its chemical characteristics, (tri (hydroxy) ethyl) silicone oil is difficult to degrade in nature. If it is widely distributed in the field, accumulated over the years, accumulated but not scattered, or seeped in the depths of the stratum, it will pollute and water sources, which will harm people's livelihood. And it may be attached to the surface of the biological body, hindering its respiration and ingestion, and the reproduction and survival of the biological body are disturbed by it.
Furthermore, the process of production and use of (tri (hydroxyl) ethyl) silicone oil, if not properly disposed of, will escape from the atmosphere, or combine with other things, resulting in malignant changes in air quality. And this thing may accumulate through the food chain layer by layer, from the tiny floating things to the huge living things, all of which are affected and damage the ecological balance.
Therefore, when using (tri (hydroxyl) ethyl) silicone oil, we should be cautious and careful to observe the various changes in its behavior between heaven and earth, in order to prevent its harm and protect the tranquility of our universe and the prosperity of all things.