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3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride

3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    349994

    Chemical Formula C7H4ClF3O4S
    Molecular Weight 276.62
    Appearance Typically a colorless to light - yellow liquid
    Physical State At Room Temperature Liquid
    Boiling Point Information may vary, around a certain temperature range related to its volatility
    Melting Point Specific melting point value depending on its purity
    Density A characteristic density value
    Solubility In Organic Solvents Soluble in many common organic solvents
    Solubility In Water Poorly soluble in water
    Reactivity Reactive towards nucleophiles due to the presence of sulfonyl chloride group
    Hazard Class Corrosive, potentially harmful if in contact with skin, eyes or ingested

    As an accredited 3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3-(trifluoromethoxy)benzene - 1 - sulfonyl chloride in sealed glass bottle.
    Storage 3-(Trifluoromethoxy)benzene - 1 - sulfonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as bases, moisture, and reducing agents. Store in a tightly - sealed container to prevent exposure to air and moisture, which could lead to decomposition. It is advisable to store it in a dedicated chemical storage cabinet, following local safety regulations for handling and storing reactive and hazardous chemicals.
    Shipping 3-(Trifluoromethoxy)benzene - 1 - sulfonyl chloride is a chemical. Shipping should be in accordance with hazardous chemical regulations, using proper packaging to prevent leakage, and transported by carriers licensed for such chemicals.
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    3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride 3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride
    General Information
    Historical Development
    3- (trifluoromethoxy) benzene-1 -sulfonyl chloride is an important product of chemical research. Tracing its historical evolution, at the beginning, researchers painstakingly explored in the laboratory, and after countless attempts, they obtained a preliminary understanding. At that time, the conditions were simple, the equipment was crude, and the progress was slow.
    However, the road of scientific research, although full of thorns, was determined by everyone. With the passage of time, science and technology have gradually advanced, experimental techniques have been improved, and the analysis of its structure and properties has become more and more accurate. Different teams have used ingenious tricks to explore new synthesis methods, and the yield has increased gradually, and the quality has also been excellent.
    With the passage of time, this product has emerged in various fields of chemical industry and is widely used. The difficulties of the past have created the brilliance of today, contributing to the progress of chemistry, and the future will also be brighter.
    Product Overview
    There is now a substance called 3- (trifluoromethoxy) benzene-1-sulfonyl chloride. This substance is quite useful in the field of chemistry. Its shape or color-specific body is also unique in nature.
    The method of its preparation can only be achieved by controlling various conditions according to exquisite chemical techniques and making various raw materials suitable for reaction. This process requires careful study of physical properties, understanding of its reaction mechanism, and careful operation to obtain pure products.
    Its wide range of uses can be used to synthesize various organic compounds, and it can be used in the fields of medicine, materials, etc. To assist in the research and development of medicine, the production of special drugs; in the creation of materials, the specificity of materials can be added.
    We chemical researchers should deeply study its nature and application, and make good use of it to promote the progress of chemistry and benefit the world.
    Physical & Chemical Properties
    There is a substance today called 3- (trifluoromethoxy) benzene-1-sulfonyl chloride. Its physical properties are often [specific color state unknown], and the smell is specific, which is difficult to describe. The melting and boiling point is also characteristic, the melting point is about [X] ° C, and the boiling point is around [X] ° C. This is the characteristic when the temperature changes.
    In terms of chemical properties, this substance is quite active. The sulfonyl chloride group is active and easily reacts with many nucleophiles, such as alcohols and amines. It is also unstable in contact with water, and can be hydrolyzed to produce corresponding sulfonic acids and hydrogen chloride gases. Due to the strong electronegativity of fluorine atoms, it has a unique electronic effect, which affects its reactivity and selectivity. In summary, the physicochemical properties of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride make it unique in organic synthesis and other fields.
    Technical Specifications & Labeling
    3- (trifluoromethoxy) benzene-1 -sulfonyl chloride is an important substance for chemical research. Its process specifications and standards (product parameters) are extremely critical. Looking at this substance, it is necessary to clarify its preparation method. From the selection of raw materials, it must be pure and refined, and the ratio is accurate. The temperature, pressure, time and other conditions of the reaction need to be precisely controlled. If there is a slight difference, the quality will be affected.
    Its quality standard, the appearance should be pure and free of impurities, and the color and luster should be normal. The content determination needs to reach the specified high purity, and the amount of impurities must be strictly limited. All physical and chemical indicators, such as melting point, boiling point, etc., must conform to the established range. In this way, high-quality 3- (trifluoromethoxy) benzene-1-sulfonyl chloride can be obtained to meet the needs of scientific research and industry.
    Preparation Method
    To prepare 3- (trifluoromethoxy) benzene-1-sulfonyl chloride, the raw materials and production process, reaction steps and catalytic mechanism are crucial. First take an appropriate amount of benzene-containing raw materials and mix them with fluorinated reagents in a specific ratio. This is the first step. The reaction is carried out in a special container and started within a suitable temperature range according to a precise temperature control program to initiate the methoxylation reaction.
    After the methoxylation is completed, transfer to the sulfonation stage. Add a sulfonating agent to adjust the reaction rate and conditions, so that the sulfonyl group is precisely connected to the specific position of the benzene ring. During the reaction process, closely monitor various indicators and fine-tune the conditions according to changes.
    In the catalytic mechanism, a dedicated catalyst is selected to accelerate the reaction and improve the selectivity of the product. It can reduce the activation energy of the reaction and make the molecules more likely to collide. The whole process requires strict control of the purity, dosage of raw materials, reaction temperature, time and catalyst dosage to produce high-purity 3- (trifluoromethoxy) benzene-1-sulfonyl chloride to meet the needs of subsequent applications.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance named 3- (trifluoromethoxy) benzene-1-sulfonyl chloride. In chemical research, its reaction and modification are very important. The reaction of this compound is related to many chemical processes, either involving nucleophilic substitution or electrophilic addition. And its modification is aimed at optimizing the characteristics, increasing stability, or strong reactivity.
    At the time of reaction, it is necessary to check its structure, clarify the properties of functional groups, and control the reaction conditions according to the reaction mechanism, such as temperature, solvent, catalyst, etc., to ensure a smooth reaction. When modifying, it is also necessary to study the molecular structure, and use subtle methods to add groups and change bonds to achieve better performance. Chemists who study the reaction and modification of this compound are expected to gain innovative results in materials, medicine, and other fields, contributing to the advancement of science.
    Synonyms & Product Names
    "On Compounds"
    Today there is a thing called 3- (trifluoromethoxy) benzene-1-sulfonyl chloride. This thing is quite important in the research of my chemistry.
    Its same name and product name also need to be investigated in detail. Those who cover the same name, either according to their nature or according to their structure, although the name is different, in fact refer to this thing. The name of the product, the established name, is recognized by the industry.
    3- (trifluoromethoxy) benzene-1-sulfonyl chloride, or other names, are all due to the difference in the viewing angle of everyone's research. However, it is fundamentally inseparable from this compound. Our researchers should be clear about the same name and product name, so that the research can be carried out without hindrance, so as not to be confused and miss the future.
    In the study of chemistry, this thing is widely used. Clarity of the same name and product name is the foundation for entering the research. Don't ignore it, it will cause things to go wrong in the future.
    Safety & Operational Standards
    3- (trifluoromethoxy) benzene-1-sulfonyl chloride safety and operating specifications
    3- (trifluoromethoxy) benzene-1-sulfonyl chloride is also a commonly used reagent in chemical synthesis. It is active in nature. When using it, when observing safety and operating standards, it is necessary to ensure that everything goes smoothly and there is no danger.
    #1. Storage requirements
    This compound should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight, cover light or cause its properties to mutate, causing accidents. And it needs to be kept away from fire and heat sources to prevent the risk of explosion. It should be stored separately from alkalis and alcohols, and must not be mixed, because it is easy to chemically react with them and cause accidents.
    #Second, the rules of operation
    When operating, it must be carried out in a fume hood to ensure air circulation and prevent the accumulation of toxic gases. The operator must wear appropriate protective equipment, such as protective glasses, to protect the eyes from splashing liquid; acid and alkali-resistant gloves to prevent skin contact; gas masks to avoid inhalation of harmful gases. When taking it, the action should be slow and handle it with care to prevent the leakage of chemicals caused by damage to the container. If there is a leak, immediately isolate the scene and evacuate unrelated personnel. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there is a large leak, it needs to be built a dike or dug for containment, and transferred to a special collector by pump for recycling or transportation to a waste treatment site for disposal.
    #3. Emergency measures
    If you accidentally touch the skin, you should quickly rinse with a large amount of flowing water for at least 15 minutes, and then seek medical treatment. If splashed into the eye, also rinse with a large amount of water, blink while flushing, and then rush to the hospital. If inhaling, quickly leave the scene to a fresh air place to keep the respiratory tract unobstructed; if breathing difficulties, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention.
    In short, the use of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride must be based on safety and strictly abide by the operating specifications to ensure experimental safety and orderly production.
    Application Area
    3- (trifluoromethoxy) benzene-1 -sulfonyl chloride is useful in various fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize pharmaceutical ingredients with unique pharmacological activities, which is expected to overcome difficult diseases and bring new opportunities for medical treatment. In the field of materials science, it can optimize the surface properties of materials through special reactions, or make materials have better corrosion resistance and wear resistance properties, and is widely used in the preparation of high-end equipment and aerospace materials. In the field of fine chemicals, this can be used as a raw material to produce a variety of high-value-added fine chemicals, such as special dyes, additives, etc., to improve the quality and functionality of chemical products. It has a wide range of application fields and is an indispensable and important substance in chemical research, which is of great significance to promote the development of various related fields.
    Research & Development
    At the beginning, the method of its synthesis was explored. After many trials and errors, the appropriate path was found. However, the selection of raw materials and the control of conditions need to be fine. If there is a slight difference, the yield will be poor.
    Then, the properties of the product were studied. Its high chemical activity is often the key in the reaction. Its stability was also observed, and it can be maintained for a long time in a specific environment. After repeated tests, the scope of its application was clear.
    As for the development, the prospects are broad. In the field of medicine, it can be used as a key intermediate to help create new drugs; in terms of materials, it is expected to give materials new energy. However, there are also challenges. The cost reduction and the excellence of the process all need to be broken. We should make unremitting efforts to develop our strengths and add brilliance to various industries.
    Toxicity Research
    Recently, in the research of compounds, its toxicity is particularly important. The toxicity of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride involved today is of paramount importance.
    Detailed investigation of this 3- (trifluoromethoxy) benzene-1-sulfonyl chloride, whose molecular structure contains trifluoromethoxy and sulfonyl chloride groups. These two may cause significant chemical activity. In the past, sulfonyl chloride is prone to react with other substances, or generate irritating and corrosive substances. The existence of trifluoromethoxy may change the polarity and fat solubility of the molecule, increasing the possibility of it entering the organism and interacting with biomolecules.
    In the process of toxicity testing, it is advisable to observe the in vitro cell model first. Observe its effects on the proliferation and apoptosis of different cell lines, such as liver and lung cells. After animal experiments were supplemented, the effects of oral and inhalation on the function and behavior of the body organs were investigated. To obtain accurate data to demonstrate the toxicity characteristics of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride, providing solid evidence for its safety use, treatment and environmental impact.
    Future Prospects
    Looking at this world, science and technology are advancing day by day, and in the field of chemical industry, new products are emerging one after another. Today there is 3- (trifluoromethoxy) benzene-1-sulfonyl chloride, and its future development is quite impressive.
    This chemical property is unique, and it may be useful in many industrial processes. With its characteristics, it may be used to create efficient medicines, add new weapons for curing diseases and treating diseases; in the field of materials science, it may help to develop materials with strange properties to meet the diverse needs of the future.
    And the tide of science and technology is surging. Scientists are working hard to explore its new uses, and may be able to emerge in the fields of electronics and energy in the future. When all is possible, this 3- (trifluoromethoxy) benzene-1-sulfonyl chloride will be an important angle for promoting future progress, and its development is limitless, which is the grand vision that our generation of researchers have hoped for.
    Where to Buy 3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride in China?
    As a trusted 3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride?
    The main use of tris (triethoxy) silicon-1-oxy-propyl trimethoxysilane is that it has key functions in many fields.
    In the construction field, it can be used as an additive for building sealants and adhesives. Because it can strengthen the bonding force of sealants and adhesives to various substrates, such as glass, ceramics, metals, etc., it can greatly improve the sealing and bonding effect, make the structure of the building more stable, and can enhance the resistance to environmental erosion and prolong the service life of building materials. For example, in curtain wall installation, the use of adhesives containing this ingredient can ensure that the bonding between the curtain wall glass and the frame is firm, and it is not easy to fall off after wind and rain.
    In the paint industry, it is an excellent adhesion promoter. Adding coatings can improve the affinity between the coating and the substrate surface, promote more uniform adhesion of the coating, and improve the adhesion and durability of the coating. Like automotive coatings, after adding this substance, the paint surface can be more firmly attached to the body, not easy to peel off, and can enhance the weather resistance of the paint surface, so that the car can remain beautiful after long-term exposure to the outdoors.
    Furthermore, in the preparation of composites, it plays an important role as a coupling agent. It can bridge the gap between inorganic fillers and organic polymer matrices, enhance the interface bonding force between the two, and improve the comprehensive properties of composites, such as strength, toughness, and heat resistance. Taking glass fiber reinforced plastics as an example, the glass fiber treated by it is more tightly combined with the plastic matrix, resulting in a significantly improved strength of the composite material, which is widely used in aerospace, automotive manufacturing and other industries that require strict material properties.
    In short, tris (triethoxy) silicon-1-oxypropyltrimethoxysilane is indispensable in many fields such as construction, coatings, and composites, and plays a crucial role in improving material properties and expanding the scope of material applications.
    What are the physical properties of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride?
    The physical properties of tris (triethoxy) silicon-1-oxypropyltrimethoxysilane are as follows:
    This substance has a certain solubility. In common organic solvents, such as ethanol, acetone, etc., it has good dissolution performance and can be evenly dispersed. This property makes it an effective dispersion medium or reaction medium in many chemical processes to help different components blend and react with each other.
    Its boiling point is also an important physical property. The specific boiling point temperature is of great significance in separation, purification and control of reaction conditions. By precisely controlling the temperature, it can achieve effective separation from other substances, or promote the smooth occurrence of related reactions within a suitable temperature range.
    The density of the substance is also a key characteristic. The appropriate density allows it to be evenly distributed in proportion when mixed with other materials, ensuring the stability and uniformity of the mixing system. In the field of composite material preparation, it has a profound impact on the uniformity and stability of the overall properties of the material.
    The characteristics of surface tension cannot be ignored. The unique surface tension allows it to exhibit specific adsorption and spreading behaviors on the surface of the material. In application scenarios such as coatings and adhesives, it helps to improve the adhesion performance of the product to the substrate and enhance the use effect of the product.
    In addition, its chemical stability is also an important physical property. Under normal environmental conditions, it can maintain relatively stable chemical properties, making it difficult to react quickly with common components in the air such as oxygen and water vapor. This property allows it to maintain its own structure and performance during storage and use, prolong the service life of the product, and ensure the reliability of the application effect.
    Is the chemical property of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride stable?
    Are the chemical properties of tris (triethoxy) silicon-1-oxypropyltrimethoxysilane stable? Both are organosilicon compounds, and their chemical properties are relatively stable, but they also depend on specific conditions.
    Let's talk about tris (triethoxy) silicon first, which contains silicon-oxygen-carbon bonds in its molecules. Silicon-oxygen bonds have high bond energy, which gives the substance a certain stability. It can exist more stably at room temperature and pressure without the action of special chemical reagents. However, in the case of strong acids and strong bases, the situation is different. Acids or bases can promote the hydrolysis of silicon-oxygen bonds, causing their structures to be damaged. For example, in a strong acid solution, the silicon-oxygen bond will gradually break, forming products such as silanol.
    As for 1-oxypropyltrimethoxysilane, it also contains silicon-oxygen-carbon bonds, and its stability is also based on this. At room temperature, it can remain stable in a dry and non-active environment. However, due to its high methoxy activity, the methoxy group can undergo hydrolysis in the presence of water. If there are nucleophiles in the environment, it may also undergo nucleophilic substitution reactions with silicon atoms, affecting its stability. Overall, these two compounds have certain chemical stability under conventional conditions, but when exposed to specific chemical environments, such as strong acids, strong bases, water, and some active reagents, their stability will be challenged, and their structures may change.
    What are the preparation methods of 3- (trifluoromethoxy) benzene-1-sulfonyl chloride?
    The preparation method of tris (triethoxy) silicon-1-chloropropylane is as follows:
    First, it can be prepared by hydrosilylation reaction between chloropropylene and hydrogen-containing silicone oil under the action of platinum catalyst. This reaction requires careful control of the reaction temperature, catalyst dosage and reactant ratio. If the temperature is too high, side reactions are prone to occur, resulting in a decrease in product purity; the amount of catalyst used is small, and the reaction rate is slow; improper ratio also affects the yield of the product. Usually in an inert gas protective atmosphere, hydrogen-containing silicone oil and chloropropylene are mixed in a certain molar ratio, an appropriate amount of platinum catalyst is added, and the reaction is stirred at a moderate temperature. After the reaction is completed, the product is purified by distillation and extraction.
    Second, trichlorosilane and ethanol are used as raw materials, and triethoxysilane is first prepared by alcoholysis reaction. This process should pay attention to the dripping speed of ethanol, reaction temperature and reaction time. The dripping speed is fast, and it is easy to cause the reaction to run out of control violently; the temperature is not suitable, the reaction is incomplete or impurities are formed; the time is too short, and the product conversion is insufficient. Subsequently, triethoxysilane reacts with chloropropene under specific conditions to synthesize the target product. During this period, various reaction conditions also need to be controlled to achieve the ideal yield and purity.
    Third, it is prepared by the Grignard reagent method. First, magnesium chips and chloropropene are made into Grignard reagent, and then it is reacted with triethoxysilane. This method has strict requirements on the reaction environment and must be an When preparing Grignard's reagent, the quality of magnesium chips and the initiation conditions of the reaction are all key. When reacting with triethoxysilane, factors such as feeding sequence and reaction temperature also have a great influence on the product. After the reaction is completed, a series of post-processing operations are used to obtain pure products.
    What are the precautions for 3- (trifluoromethoxy) benzene-1-sulfonyl chloride in storage and transportation?
    Tris (triethoxy) silicon-1-hydroxypropyl chloride requires attention to many matters during storage and transportation.
    When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. This is because the substance may be sensitive to humidity and temperature. If the environment is humid, water vapor may react with the substance and cause it to deteriorate; if the temperature is too high, it may also cause chemical reactions and damage its quality. And it needs to be kept away from fire and heat sources to prevent the risk of fire or explosion, because it may be flammable or chemically unstable.
    Furthermore, the choice of storage containers is also critical. A well-sealed container must be selected to avoid excessive contact with the air, prevent oxidation or absorb impurities in the air. There are also requirements for materials. Materials that do not chemically react with the substance should be selected, such as specific corrosion-resistant metal or plastic containers, to ensure the purity and stability of the substance.
    In terms of transportation, the packaging must be stable. Make sure that the packaging is not damaged or leaked during transportation due to bumps and collisions. Transportation vehicles must meet relevant safety standards and be equipped with fire and explosion-proof safety equipment. Transport personnel should also be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies, they can respond quickly and correctly.
    In addition, transportation documents are also indispensable. It is necessary to specify the name, nature, hazard and emergency measures of the substance in detail, so that personnel in all aspects of transportation can understand and prepare for corresponding protection and response. In this way, tri (triethoxy) silicon-1-hydroxypropyl chloride can be kept safe during storage and transportation.