3-Iodine-1- (trifluoromethoxy) benzene is also an organic compound. It has a wide range of uses and is an important raw material in the field of organic synthesis.
One of them is often the key building block for the construction of complex organic molecules. Due to the high activity of iodine atoms, it can be combined with various nucleophilic reagents through many nucleophilic substitution reactions. For example, in palladium-catalyzed cross-coupling reactions, it can react with carbon-containing nucleophilic reagents such as organoboronic acid and organotin reagents, so as to achieve the construction of carbon-carbon bonds. This reaction is of great significance for the synthesis of organic compounds with specific structures and functions, especially drug molecules and natural products.
Second, it has also emerged in the field of materials science. Due to the special electronic and spatial effects of the trifluoromethoxy group contained in the molecule, it can endow the material with unique physical and chemical properties. For example, introducing it into polymer materials may improve the solubility, thermal stability and electrical properties of the material, and then apply it to electronic devices and optical materials.
Third, in pharmaceutical chemistry research, the structural unit of this compound may promote drug activity. By modifying and modifying its structure, drug molecules with novel mechanisms of action and good biological activity can be developed, providing a broad space and possibility for the creation of new drugs.
In conclusion, 3-iodine-1 - (trifluoromethoxy) benzene plays an indispensable role in many fields such as organic synthesis, materials science, and medicinal chemistry.

3-Iodine-1- (trifluoromethoxy) benzene is a kind of organic compound. Its physical properties are quite critical, and it is related to many characteristics and uses of this compound.
First appearance, under room temperature and pressure, it is often colorless to light yellow liquid, with pure color and uniform texture. It can be seen in sunlight with its clear luster, like a clear liquid, emitting a unique smell, but the smell is not pungent, and it has a slightly aromatic aroma unique to organic compounds.
When it comes to the melting point, it is about -20 ° C. Under this temperature condition, the substance quietly melts from solid to liquid, the intermolecular forces change, the lattice structure gradually disintegrates, and the particle movement is more free.
In terms of boiling point, it is about 180-185 ° C. When it rises to this temperature range, the molecule obtains enough energy to break free from the shackles of the liquid phase and escape into a gaseous state. At this temperature range, a large number of bubbles are generated inside the liquid, tumbling and boiling, like a smart dance, and the material state realizes the transition from the liquid phase to the gas phase.
The density is about 1.8-1.9 g/cm ³. Compared with water, its density is relatively large. If mixed with water, it will sink to the bottom, just like heavy objects entering water, and it will be clearly stratified.
In terms of solubility, this compound is difficult to dissolve in water because its molecular structure is rich in non-polar groups, and the polarity difference between it and water molecules is large. According to the similar principle of miscibility, the two are difficult to blend. However, it has good solubility in organic solvents such as dichloromethane, chloroform, and ether, just like fish entering water, it can closely embrace and disperse organic solvent molecules evenly.
Vapor pressure is also an important property. At room temperature, the vapor pressure is lower, indicating that its volatility is relatively weak, and the tendency of molecules to escape from the liquid phase to form the gas phase is small. In a closed container, the number of gas phase molecules is limited, and when the gas phase and the liquid phase reach dynamic equilibrium, the gas phase pressure is lower.
In summary, the physical properties of 3-iodo-1- (trifluoromethoxy) benzene, such as appearance, melting point, density, solubility, and vapor pressure, are unique and interrelated, and are of great significance for its storage, transportation, and use. It helps people better understand and use this compound.

The synthesis of 3-iodo-1- (trifluoromethoxy) benzene can be achieved by the following methods.
First, 3-hydroxy-1- (trifluoromethoxy) benzene is used as the starting material. This hydroxy benzene is first replaced by an iodine atom with an iodine substitution reagent, such as potassium iodide and hydrogen peroxide, under appropriate solvent and reaction conditions, and the hydroxy group can be replaced by an iodine atom to obtain the target product 3-iodo-1- (trifluoromethoxy) benzene. In this process, the choice of solvent is very critical. Common ones such as dichloromethane, N, N-dimethylformamide, etc., can be used according to the actual reaction conditions. The reaction temperature and time also need to be precisely controlled. Usually, the temperature is in the range of room temperature to moderate heating, and the reaction ranges from several hours to ten hours before the reaction can reach a more ideal level.
Second, start from 3-nitro-1- (trifluoromethoxy) benzene. First, the nitro group is reduced to an amino group under the action of a suitable reducing agent, such as iron and hydrochloric acid system, or hydrogen under the action of a catalyst (such as palladium carbon), to obtain 3-amino-1- (trifluoromethoxy) benzene. Then, the amino compound is diazotized with sodium nitrite and potassium iodide in an acidic medium, and then the diazonium salt is replaced by iodine ion, and finally 3-iodine-1- (trifluoromethoxy) benzene is formed. This path step is slightly complicated, but the reaction conditions of each step are relatively mild and the yield is guaranteed. During the diazotization reaction, the temperature should be strictly controlled at a low temperature to prevent the decomposition of the diazonium salt, generally at 0-5 ℃.
Third, the iodization reaction is carried out directly with 1- (trifluoromethoxy) benzene as the substrate. However, due to the trifluoromethoxy group on the benzene ring as an electron-absorbing group, the electron cloud density of the benzene ring is reduced, and direct iodization is more difficult. High-activity iodizing reagents, such as N-iodosuccinimide (NIS), and an appropriate amount of Lewis acid catalyst, such as aluminum trichloride, are required to promote the reaction. Although this reaction route is short, the reaction selectivity needs to be carefully controlled to prevent the formation of multi-iodide by-products. The reaction solvent can be chloroform, dichloroethane, etc. The reaction is carried out at low temperature or room temperature to improve the reaction selectivity and yield.

3-Iodine-1- (trifluoromethoxy) benzene is an important raw material for organic synthesis. When storing and transporting, several things should be taken with care.
First words storage. This substance should be stored in a cool, dry and well-ventilated place. It is more sensitive to heat, and high temperature is easy to decompose and damage its quality. Therefore, it should be kept away from heat sources and fire sources, and the temperature should be controlled within a specific range to prevent accidents. In addition, it needs to be stored separately from oxidants, acids and other substances. Because of its active chemical properties, it is easy to react with various substances. If stored in combination, it may cause violent reactions and cause safety risks. Storage containers should also be carefully selected. Corrosion-resistant materials, such as glass or specific plastic materials, should be used, and they should be tightly sealed to avoid contact with air and moisture and prevent their deterioration.
As for transportation, there are also many requirements. Before transportation, make sure that the packaging is complete and firm. Packaging materials should be able to resist vibration, collision and friction to prevent material leakage caused by container damage. During transportation, vehicles should choose a smooth route to avoid high temperature and dense fire sources. At the same time, transportation personnel must be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods. If a leak occurs during transportation, it should be dealt with immediately according to the predetermined emergency plan, evacuate the crowd, isolate the scene, and properly collect and clean up the leakage to prevent pollution of the environment and personal safety. In conclusion, the storage and transportation of 3-iodine-1-trifluoromethoxy benzene requires careful care to ensure its quality and safety.

I think this 3 - Iodo - 1 - (Trifluoromethoxy) Benzene is also an organic compound. Its market price often varies due to various factors.
The first to bear the brunt is the difficulty of production. If the preparation of this compound requires complicated steps, high raw materials, and low yield, its price will be high. If it is difficult to prepare, the cost will increase greatly. In order to make a profit, merchants must raise its price.
Furthermore, the supply and demand of the market is also the key. If the demand for this product in the pharmaceutical, material and other industries is strong, but the supply is limited, the so-called "rare is expensive", its price will rise. On the contrary, if there is little demand and sufficient supply, the price will decline.
Repeat, purity also affects the price. High purity 3 - Iodo - 1 - (Trifluoromethoxy) Benzene is more difficult to prepare, and it is very much needed in high-end scientific research and special industrial applications, so its price is higher than that of low purity.
Looking at the market conditions in the past, the price of such compounds fluctuated from a few dollars to tens of dollars per gram. However, this is only a rough figure. Due to the vagaries of the market, the market conditions vary from place to place. In busy commercial cities, due to factors such as logistics and market competition, the price may vary from that in remote places.
To obtain an accurate market price, please consult the chemical products trading platform, consult relevant suppliers, or refer to recent industry reports to obtain a more accurate price.