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3-Fluorobenzenesulfonyl Chloride

3-Fluorobenzenesulfonyl Chloride

Hongda Chemical

Specifications

HS Code

210399

Chemical Formula C6H4ClFO2S
Molar Mass 196.61 g/mol
Appearance Colorless to pale yellow liquid
Density 1.48 g/cm³
Boiling Point 118 - 120 °C at 20 mmHg
Solubility In Water Reacts with water
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Flash Point 110 °C
Pungency Strongly pungent odor
Hazard Class Corrosive, harmful if swallowed, in contact with skin or if inhaled

As an accredited 3-Fluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluorobenzenesulfonyl chloride packaged in a sealed glass bottle.
Storage 3 - Fluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. It must be kept away from heat, flames, and moisture as it is reactive. Store it in a tightly - sealed container, preferably made of corrosion - resistant materials. Avoid storing it near incompatible substances like strong bases. Proper labeling of the storage container is crucial for easy identification and safety.
Shipping 3 - Fluorobenzenesulfonyl chloride, a hazardous chemical, is shipped in well - sealed, corrosion - resistant containers. It follows strict regulations, ensuring proper labeling and handling during transit to prevent leaks and ensure safety.
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3-Fluorobenzenesulfonyl Chloride 3-Fluorobenzenesulfonyl Chloride
General Information
Historical Development
3-Fluorobenzenesulfonyl chloride is also a chemical material. Its origin is also, at the beginning of the people in the chemical exploration of the deepening, the study of all kinds of compounds more and more intensive. At that time, the desire for knowledge was like a blazing fire, hoping to obtain new things to expand the frontier of chemical industry.
In the past, all the wise men were in the laboratory, thinking hard and trying in different ways. Or adjust the ratio of various things, or change the temperature and pressure of the reaction, and test back and forth, after a bad road. What you get at the beginning is not satisfactory, but those who are determined are discouraged.
When you catch a certain time, a method gradually becomes effective. With a specific raw material, according to the delicate order, after multiple steps, the 3-fluorobenzenesulfonyl chloride was finally obtained. Since then, it has emerged in the field of chemical industry, and its use has become wider. It has its own merits in synthesis. Later generations have also inherited the work of predecessors and continuously refined its production to make it more perfect, adding a brilliant chapter to the history of chemical industry.
Product Overview
3-Fluorobenzenesulfonyl chloride is also an organic compound. It may be a colorless to light yellow liquid with a pungent odor. This substance has a wide range of uses in the field of organic synthesis and is often the key raw material for the preparation of various fluorine-containing organic sulfonates.
Its chemical properties are active, and the sulfonyl chloride group easily reacts with many nucleophilic reagents, such as alcohols and amines, to form corresponding sulfonates and sulfonamides. By introducing fluorine atoms, the prepared products are endowed with unique physical and chemical properties, such as enhanced lipid solubility and improved chemical stability.
When preparing, it is often necessary to carefully control the reaction conditions, such as temperature, reactant ratio and catalyst use, to ensure yield and purity. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent accidents.
Physical & Chemical Properties
3 - Fluorobenzenesulfonyl Chloride, it is also a chemical substance. Its properties are both physical and chemical. Its color or color, it is liquid, and it is irritating. Melting and boiling have their own characteristics, low melting, and melting in case of boiling. In boiling, add boiling.
Its chemical properties, the activity is often. Sulfonyl chloride activity, easy to react to other substances. In case of alcohol, sulfonate is formed; in case of amine, sulfonamide is generated. This is all due to the characteristics of sulfonyl chloride, its reaction is fast, and it can be made into a variety of useful substances. In the field of synthesis, the use is very good. Physical chemical properties, the characteristics of this substance, in chemical research and industrial life, are all important.
Technical Specifications & Labeling
There is 3-fluorobenzenesulfonyl chloride today, and its technical specifications and identification (product parameters) are the key. In terms of technical specifications, the synthesis method needs to be accurate and correct. The selection of raw materials should be pure and excellent, and the reaction conditions such as temperature, pressure, and duration should be strictly controlled. If the temperature is too high or side reactions will breed, and if it is too low, the reaction will be slow or difficult to achieve expectations. The same is true for pressure, which is related to the reaction rate and product purity.
On the label (product parameters), the appearance should be clear, and the color, shape, etc. should be accurately described. Purity must be accurately determined, which is related to the quality of the product. The content of impurities needs to be strictly limited, and trace impurities may affect their application in various fields. In this way, it is possible to ensure that the 3-fluorobenzenesulfonyl chloride product meets the requirements and lays a solid foundation for various uses.
Preparation Method
The preparation method of 3-fluorobenzenesulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are mainly fluorobenzene and chlorosulfonic acid. First take an appropriate amount of fluorobenzene and place it in a special reactor. The kettle needs to have good sealing and temperature control performance. Slowly add chlorosulfonic acid, and strictly control the reaction temperature during the process, about 50 to 60 degrees Celsius. This is the key temperature range, which is related to the reaction rate and product purity.
During the reaction, pay close attention to the changes in the kettle and stir in a timely manner to promote full contact between the two. The reaction takes several hours, and the product gradually forms when the reaction is smooth. Subsequent separation and purification, the unreacted raw materials and products are initially separated by distillation, and then refined steps such as extraction and crystallization are taken to obtain pure 3-fluorobenzenesulfonyl chloride. In terms of catalytic mechanism, specific catalysts, such as some metal salts, can be added moderately to speed up the reaction process and improve the yield. The whole process requires strict compliance with operating procedures to ensure safe production and product quality.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is related to the change of substances, especially 3-Fluorobenzenesulfonyl Chloride. It has its own uses in chemical reactions, if the stars are in the sky.
To observe its reaction, or when it encounters nucleophilic reagents, the nucleophilic substitution changes. Sulfonyl chloride has strong activity and is easy to be replaced by other groups to form new compounds. However, the reaction environment, temperature, pressure, and the proportion of agents are all important factors. A slight difference of a millimeter, or the effect of the reaction is different.
As for the change of its nature, the method of modifying the structure can be used. Adding other groups to the benzene ring, or the position of regulating fluorine, can change its electron cloud cloth and change its physicochemical properties. In this way, it can adapt to different needs, develop its talents in the fields of medicine and materials, and open a new path in the way of chemical engineering. Those who learn should study it in detail to understand its mysteries and apply it to the world.
Synonyms & Product Names
3-Fluorobenzenesulfonyl chloride, which is also known as another name. Although the ancient chemistry is not as clear as it is today, there are many substances that exist under different names. 3-Fluorobenzenesulfonyl chloride, or another name for its properties and uses. Looking at its name, "fluorobenzenesulfonyl chloride", it is named after its composition and structure. Or there are regional differences, in a certain place, it is called by another name, but it all refers to this thing.
The road of chemistry, exploring the properties of substances, 3-fluorobenzenesulfonyl chloride has its unique use in various reactions. Although this precise name was not available in ancient times, the reactions and phenomena related to it may have been recorded for a long time. Today's researchers, when tracing their roots and finding the origin of their nicknames, can also find clues in ancient books, contribute to chemical research, explore the whole picture, and understand their past titles in order to clarify the development of this thing.
Safety & Operational Standards
3-Fluorobenzenesulfonyl chloride safety and operating specifications
Fu 3-fluorobenzenesulfonyl chloride is also a common raw material in chemical preparation. It is active, highly corrosive and irritating, so when it is taken, stored and operated, it should be strictly observed to ensure safety.
First words storage. This chemical should be placed in a cool, dry and well-ventilated place, away from fires and heat sources. Due to heat or open flames, there may be a violent reaction, resulting in a dangerous situation. And should be stored separately from oxidants, bases, etc., and must not be mixed to prevent interaction and cause accidents.
As for the operation, the operator must wear professional protective equipment, such as protective clothing, protective gloves and protective masks, to avoid contact with the skin and eyes. If you accidentally touch it, you should immediately rinse with a lot of water, and then seek medical treatment. It is best to operate in a fume hood to disperse volatile gases and avoid inhalation into the body.
Furthermore, when taking it, the action should be slow, and the appliance must be clean and dry. Due to the trace amount of moisture or impurities, it may affect its quality and even trigger dangerous reactions. After use, properly seal the container to prevent leakage.
In case of leakage, the surrounding personnel should be evacuated immediately, and fire should be strictly prohibited from approaching. Emergency responders need to wear professional protective equipment to block the leakage source first, and then absorb the residue with inert materials such as sand and vermiculite, and dispose of it according to regulations after collection.
In short, although 3-fluorobenzenesulfonyl chloride is quite effective in the chemical industry, its potential danger cannot be underestimated. Only by abiding by safety and operating standards can personnel be safe, production can be smooth, and disasters can be avoided before they happen, resulting in the prosperity of the chemical industry.
Application Area
3-Fluorobenzenesulfonyl chloride is a chemical substance. Its application field is quite wide. It is often a key raw material in the synthesis of medicine. The introduction of fluorine atoms can change the physical and chemical properties and biological activities of compounds. Based on this substance, chemists can make many special drugs to treat various diseases.
In the field of material science, it also has its uses. After a specific reaction, its structure can be integrated into polymer materials, giving the material unique properties, such as enhancing the stability and corrosion resistance of the material.
Furthermore, in the field of organic synthetic chemistry, it can be used as a sulfonylation agent. React with various organic substrates, introduce sulfonyl groups, expand the types and functions of organic compounds, and contribute to the development of organic synthetic chemistry. In short, 3-fluorobenzenesulfonyl chloride has important value in many application fields and promotes the progress of related disciplines and industries.
Research & Development
Recently, in the field of chemistry, I have focused on the research of 3-Fluorobenzenesulfonyl Chloride. This substance has unique properties and shows unique performance in many reactions.
I have carefully investigated its preparation method, and strive to improve the process, improve the yield and purity. After repeated experiments, the ratio of raw materials and reaction conditions have been improved, and the results have gradually become apparent.
And explore its application in the field of organic synthesis. It can be used as a key intermediate to derive a variety of high-value compounds. This research result is expected to open up a new path for industrial production.
With time, we will continue to study and explore its potential in depth, promoting the wide application of this chemical in more fields, contributing to the development of chemistry, and promoting its expansion from research to practical application.
Toxicity Research
The industry of chemical industry is related to all things, but the study of poisons in it is very important. Today, 3-Fluorobenzenesulfonyl Chloride is used to discuss it.
The toxicity of this substance cannot be ignored. It is irritating to the skin and eyes. If you touch it carelessly, you will cause pain. If it enters the mouth and nose, it will also damage the respiratory system, causing coughing and asthma.
We study the toxicity of this substance, and observe its chemical and physical properties in detail. We test it with white pigs and guinea pigs to observe its reaction. It is also tested in the environment to observe its impact on water, soil and vegetation.
Knowing the harm of toxicity, we study protection strategies. When working, wear protective clothing, goggles, and masks in front of you to prevent contact. If you accidentally touch it, rinse it with water quickly, and seek medical treatment for those who are serious.
Hope that those in the same industry will focus on toxicity research, abide by safety regulations, protect their own and everyone's well-being, and travel steadily and far in the chemical industry.
Future Prospects
I have studied 3 - Fluorobenzenesulfonyl Chloride. Looking at its properties, it has unique chemical properties and seems promising in the field of organic synthesis.
In the future, it may be able to emerge in the creation of medicine. With its structural characteristics, it may be able to participate in subtle reactions and help the molecular structure of new drugs. And in chemical production, it is also expected to optimize the process, reduce costs and increase efficiency.
Or open up new paths in materials science. After ingenious modification, or giving new energy to materials, such as improving their stability and conductivity, it is applied to high-tech materials, with broad prospects. Although there may be thorns in the road ahead, with time and careful study, we will be able to tap its potential, add new colors to various fields, and explore the infinite possibilities of the future.
Where to Buy 3-Fluorobenzenesulfonyl Chloride in China?
As a trusted 3-Fluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 3-fluorobenzenesulfonyl chloride?
3-Bromothiophene is blue and oily, and its physical properties are as follows:
This substance is blue and oily at room temperature, and it has a unique color appearance. Its boiling point is about 150-151 ° C. At this temperature, the substance gradually transforms from liquid to gaseous state, showing its gas-liquid phase transition characteristics. The melting point is about -37 ° C. When the temperature drops to this value, the substance will solidify from liquid to solid state, which is the key node of its solid-liquid phase transition.
The density of 3-bromothiophene is about 1.579g/cm ³, which is higher than that of common water. Therefore, if placed in water, it should be submerged underwater. It has a certain solubility and is soluble in organic solvents such as ethanol and ether. Due to the principle of "similar miscibility", its molecular structure has a certain interaction force with the molecules of organic solvents, resulting in uniform dispersion. However, the solubility in water is not good, because the polarity of water is quite different from the structure of 3-bromothiophene, and the interaction force is weak.
In addition, 3-bromothiophene is volatile, which can be slowly volatilized in air and dissipated from the surrounding environment. Its smell is unique, although it is difficult to express it accurately, it can be distinguished from the smell of common substances. Its vapor relative density is greater than that of air. If it evaporates in a limited space, the vapor tends to accumulate in the lower part of the space. All these physical properties are essential for understanding and studying 3-bromothiophene.
What are the chemical properties of 3-fluorobenzenesulfonyl chloride?
3 - Glycyrrhizite is one of the most important, and its chemical properties are very special. The main component of glycyrhizite is carbonate (ZnCO), and it also contains a small amount of oxidation (MgO), oxidation (Fe 2O O), oxidation (MnO) and other substances.
In terms of its chemical properties, the carbonation properties are not determined. However, when encountering acid, carbonation can be produced inversely. Taking acid as an example, its inverse formula is: ZnCO 🥰 + 2HCl = ZnCl 🥰 + H 🥰 O + CO 🥰 ↑. In this inverse, carbonation acts as an acid to generate chlorination, water and carbon dioxide.
Furthermore, due to the small amount of gold oxides, such as oxidation, it also exhibits some phase transformation properties. Oxidation can react to acids, such as sulfuric acid, to generate magnesium sulfate and water. The reverse formula is: MgO + H2O SO = MgSO + H2O.
The use of
in China is based on the chemical properties of glycerite, such as calcination and quenching. Its components may be formed to a certain extent, so that it has the functions of retardation, recovery and quenching. It is widely used in the treatment of ophthalmology, dermatology and other diseases. In addition, the rich chemical properties of glycerite lay the foundation for its use in China.
What are the main applications of 3-fluorobenzenesulfonyl chloride?
3-%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF is a wonderful thing of spiritual deficiency, its use is wide, and it is involved in all kinds of fields.
One is in the field of medicine. Ancient doctors know the spirituality of this medicine. With it as medicine, it can adjust qi and blood, and heal various diseases. In case of poor qi and blood, and incompatibility of the viscera, 3-%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF can smooth the qi and veins, make the qi and blood flow back to normal, and help patients get rid of diseases and health. Because it contains the essence of heaven and earth, it can be in harmony with the veins of the human body, so it is indispensable in medicine.
The second is in the way of alchemy. Alchemists regard 3-%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF as a rare thing. Using it to enter the pill can increase the spirituality of the pill and mention the efficacy of the pill. When refining magic treasures, integrating this liquid can greatly increase the spirituality of magic treasures, be sturdy and abnormal, and have unique power. This is all because of its magical quality, which can nourish each other with pills and utensils, and rejuvenate the spiritual light together.
Third, in the realm of spiritual plant cultivation. The growth of spiritual plants requires the nourishment of spiritual objects. 3-%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF sprinkled on the side of spiritual plants can help spiritual plants absorb the spiritual energy of heaven and earth and thrive. It can make spiritual plants more green leaves, more colorful flowers, and more spiritual effects. Therefore, in the cultivation of spiritual plants, this liquid is an indispensable help.
Fourth, in the setting of feng shui magic arrays. Feng shui masters often use 3-%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF as a guide. Dripping this liquid into the eye of the formation can enhance the spiritual power of the formation, make the operation of the formation smoother, and the effect is more significant. Because it can communicate the spiritual power of heaven and earth, and make the formation blend with the spiritual energy of heaven and earth, it is also important in the field of feng shui formation.
What are the preparation methods of 3-fluorobenzenesulfonyl chloride?
To make the medicine of the finless porpoise, there are various ancient techniques, which are described here for you.
First, it is based on spiritual grass. Find the rare spiritual grass in the dense forest of the mountains. Its leaves need to have strange lines, and the stems are purple and red. On the night of the new moon, pick it with a clean utensil. When picking, you need to have no distractions in your heart, and say prayers to the gods of grass and trees. Place the collected spiritual grass in a stone mortar, add it to the morning dew, and pat it carefully into a paste for later use. This spiritual grass is regarded as a condensation of the essence of nature, or contains the spiritual effect of sympathizing with the finless porpoise.
Second, supplemented by the scales of auspicious beasts. When I smell the ancient auspicious beasts, their scales have mysterious power. Although the auspicious beast is hard to find, it can be found in the places where rumors haunt. If you get a piece of auspicious beast scales, use the heat to slow down until it is slightly burnt and studied into fine powder. The auspicious beast is a symbol of auspiciousness, and its scales may be able to activate the spirit of the finless porpoise and make it manifest.
Third, use the holy water of rivers and rivers. At the source of the great river, take clear water and fill it with jade bottles. This water has been nourished by the mountains and rivers, and has the spirit of heaven and earth. Pour the pre-made spiritual grass paste and auspicious beast scale powder into the holy water, stir well, seal it in a porcelain jar, and bury it in the pure soil by the river for seventy-seven or forty-nine days. Break the soil and take it out, and make it a medicine.
Fourth During the whole process of pharmacy, someone who is well versed in spells is required to recite a specific spell next to the medicine every day. The spell originates from the ancient inheritance and is injected into the medicine with spiritual power to strengthen the effect of the medicinal power and the consonance of the finless porpoise.
However, this is all an ancient fantasy method. The finless porpoise is a living being, and it is not forced to appear by magic. At this time, it is time to protect the ecology and protect the habitat of the finless porpoise.
What are the precautions for 3-fluorobenzenesulfonyl chloride during storage and transportation?
3-% acrylic fiber shows blue light during storage and transportation, the following matters should be paid attention to:
First, moisture resistance is essential. Acrylic fiber is hygroscopic, and moisture can easily cause its properties to change. When storing, choose a dry place and avoid a humid place. If the warehouse has heavy moisture, a desiccant can be placed to absorb moisture. During transportation, also ensure that the packaging is tight and protected from rain to prevent the fiber strength from being reduced and the color from changing due to moisture.
Second, temperature control cannot be ignored. High temperature can easily damage the properties of acrylic fiber, making the fiber soft, deformed or even melted. The temperature at the storage place should be kept moderate and should not exceed 35 ° C. When transporting in summer, special attention should be paid to the temperature in the compartment. Ventilation, shading and other cooling methods can be taken to avoid high temperature affecting the quality of acrylic fibers.
Third, anti-heavy pressure is also the key. Acrylic fibers are easily deformed under heavy pressure, which affects the appearance and quality. When stacking, the number of layers should not be too much, and it is necessary to ensure that the bottom goods can bear the weight of the upper layer. During the handling process, it should also be handled with care. It should not be loaded and unloaded brutally to avoid local deformation or damage.
Fourth, it is necessary to keep away from fire sources. Acrylic fibers are mostly flammable materials. When storing and transporting, be sure to keep away from open flames, high temperature equipment and flammable and explosive items. Warehouses and transportation vehicles should be equipped with At the same time, the operator must also strictly abide by the fire protection regulations, and do not smoke or carry out open flame operations in the work area.
Fifth, the packaging must be in good condition. Good packaging can protect the acrylic fiber from external factors during storage and transportation. Packaging materials should have moisture-proof, dust-proof and damage-proof properties, and product information and precautions should be clearly marked on the packaging for identification and management.