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3-Fluorobenzenesulfonamide

3-Fluorobenzenesulfonamide

Hongda Chemical

Specifications

HS Code

461321

Chemical Formula C6H6FNO2S
Molar Mass 175.18 g/mol
Appearance Solid
Color White to off - white
Melting Point 124 - 128 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Vapor Pressure Low

As an accredited 3-Fluorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluorobenzenesulfonamide packaged in a sealed, labeled container.
Storage 3 - fluorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. It is advisable to store it separately from incompatible substances to avoid chemical interactions that could pose risks.
Shipping 3 - Fluorobenzenesulfonamide is shipped in well - sealed containers, compliant with chemical transportation regulations. Packaging ensures protection from moisture and physical damage during transit to safeguard product integrity.
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3-Fluorobenzenesulfonamide 3-Fluorobenzenesulfonamide
General Information
Historical Development
3 - Fluorobenzenesulfonamide, the historical development of its matter, although not famous in ancient times, but the progress of chemical industry, gradually obvious. In the past, the research of chemistry has not yet reached this state, and the knowledge of various compounds is still shallow.
Catch the gradual development of science and technology, researchers explore the secrets and hide, and have made many achievements in the field of organic synthesis. 3 - Fluorobenzenesulfonamide has begun to emerge, and researchers have exhausted its properties and investigated its uses. At first, it was only an experimental object, and it was observed in a small room to observe its changes and analyze its reactions.
After the years passed, it was known that it may be useful in medicine and materials industries. As a result, various parties competed for research, and the craftsmanship became more and more refined, and the amount of production also gradually increased. Since the end of the year, it has become the most important in the industry. Its historical development depends on the diligence of researchers and the progress of science and technology.
Product Overview
3 - Fluorobenzenesulfonamide is a unique compound. Its properties, the appearance is often white to white crystalline powder, pure and fine. Its smell is weak and almost invisible. In terms of solubility, it is slightly soluble in water, but easily soluble in some organic solvents, such as ethanol, acetone, etc. This characteristic makes it exhibit unique behavior in various chemical operations and reaction systems.
In terms of its chemical properties, sulfonamide groups give it a certain reactivity and can participate in many organic synthesis reactions, such as substitution reactions with nucleophiles, to build novel chemical structures. The introduction of fluorine atoms significantly changes the electron cloud distribution of molecules, enhances its stability and biological activity, and has broad application prospects in the fields of medicine and pesticide creation. With such unique physical and chemical characteristics, 3-Fluorobenzenesulfonamide has emerged in cutting-edge fields such as fine chemicals and drug research and development, and has become a key material for scientific research exploration and industrial innovation.
Physical & Chemical Properties
3 - Fluorobenzenesulfonamide, it is also possible to study the physicalization of things. Its shape, often solid, color or white or near color, and uniform. Its melting quality, which is obtained by measuring its properties, reflects the effect of its molecular force.

And solubility, in some soluble materials, the degree of solubility varies. The solubility of this solution, the molecular phase. The dissolution of similar properties, or can make it soluble, and those with special properties, dissolve.
Its chemical activity, can also be. The functionalities it contains, its specific inverse properties. In some reactions, other things can be interacted with atoms or groups in a specific way, showing the wonders of transformation. All this physical and chemical properties is the cornerstone of a deep understanding of this thing and its application in multiple domains.
Technical Specifications & Labeling
3 - Fluorobenzenesulfonamide, the chemical substance is also. Its technical specifications and identification (product parameters) are the key. In terms of its properties, when it is a white crystalline powder, the smell is weak. The melting point should be within a specific range, which is related to its stability. The purity must reach a high standard to ensure excellent quality.
On the label, there should be a clear chemical name and structural formula, so as to correct the audio and visual. Safety labels are also indispensable, marking its toxicity and hazards, so that the user can understand its risk. Storage regulations should be protected from moisture, heat insulation, and placed in a cool and ventilated place to prevent deterioration. During transportation, according to its characteristics, choose the appropriate method and comply with relevant regulations to ensure safe transportation. In this way, the technical specifications and labels of the 3-Fluorobenzenesulfonamide are comprehensive, and the research is orderly.
Preparation Method
The formulation method of 3-fluorobenzene sulfonamide is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials should be based on fluorobenzene and sulfonylation reagents. First take an appropriate amount of fluorobenzene, according to a certain ratio, and mix it with the sulfonylation reagent. This step requires precise dose control to achieve the best reaction effect.
At the beginning of the reaction, under a specific temperature and pressure environment, the two slowly react. The temperature should be controlled in a moderate range, and the pressure should also be stable to make the reaction progress smoothly. During the reaction process, a suitable catalyst is added to use its catalytic mechanism to accelerate the reaction rate and improve the purity of the product.
After several reaction steps, the reactants are gradually converted. At first, the two interact and the molecular structure gradually changes; then, through a series of complex reactions, the target product 3-fluorobenzenesulfonamide is gradually formed. Finally, through separation, purification and other processes, the pure 3-fluorobenzenesulfonamide product is obtained. The whole preparation process requires fine operation, and each link is closely linked to ensure the quality and yield of the product.
Chemical Reactions & Modifications
Today there is a thing, called 3-Fluorobenzenesulfonamide, in the field of chemical research, its chemical reaction and modification are quite critical.
Look at its reaction, or with various reagents, through combination and decomposition, such as the ancient Dan sand burned into mercury, and the product changes and has a new quality. When this substance reacts, it needs to be controlled by temperature and pressure, and its rate is observed. If the heat is subtle, it is about success or failure.
When it comes to modification, you want to increase its characteristics, or change its structure, or add its groups. If you carve beautiful jade with good craftsmanship, do it carefully, and hope to get better performance. After modification, it may be used in new fields, such as medicine and materials, and the effect will be very different from the past. When studying this matter, we should study it diligently, understand its principles, and make every effort for the advancement of chemistry, so that it can be widely used and effective.
Synonyms & Product Names
Today there is a thing called 3-Fluorobenzenesulfonamide. The synonyms and trade names of this thing are the gist of our research. In my pursuit of chemistry, I know that there are many things in one thing. This 3-Fluorobenzenesulfonamide, or has another name, or has different trade names.
Study its synonyms, or derive according to its chemical structure, nature, or vary by region and industry habits. The determination of a trade name is often related to market and publicity factors.
We should study it carefully, identify its synonyms, and explore the origin and changes of trade names. It is hoped that the synonyms and trade names of this object can be used to obtain a clear and complete understanding, so that the chemical research and application can be accurate and correct, without confusion or error, so as to facilitate the progress of chemical industries.
Safety & Operational Standards
3 - Fluorobenzenesulfonamide is an important chemical substance. Safety and standardization are of paramount importance for its experimental operation.
Before operation, read the relevant materials carefully to be familiar with its physicochemical properties and latent risks. When using it, it is best to do it in a fume hood in a well-ventilated environment to prevent the accumulation of harmful gases.
When touching this substance, protective measures are indispensable. Wear suitable protective clothing, gloves and goggles to avoid contact with skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention if necessary.
During operation, strictly follow established norms. The equipment used must be clean, dry and suitable. Weighing should be accurate so as not to affect the experimental results and subsequent use. Heating, stirring and other operations should be carried out according to the standard process and cannot be changed.
Storage is also exquisite. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Properly marked for identification and use, and regularly check the storage conditions and material status.
Waste treatment should also not be underestimated. According to relevant regulations, collect waste containing 3-Fluorobenzenesulfonamide and hand it over to professional institutions for treatment. It is strictly forbidden to discard it at will to avoid polluting the environment.
In short, the safety and standard operation of 3-Fluorobenzenesulfonamide needs to be kept in mind by the experimenter at all times, and meticulous to ensure the safety of personnel and the smooth experiment.
Application Area
3 - Fluorobenzenesulfonamide, it is also a chemical product. Its use, in the field of production, can be made of raw materials. Because of its unique chemical properties, it can be used to multiply and reverse, helping to create special effects. And in the process, it can be used to increase efficiency, improve its characteristics, and increase the effect of anti-damage and anti-damage. It can also be used in materials science to assist in the research of new materials to meet the needs of each. Its use in different fields, all of which can be used to create new materials, promote multi-line progress, and develop extraordinary value, which is indispensable for today's technology exhibition.
Research & Development
In recent years, I have made many achievements in my research on 3-Fluorobenzenesulfonamide. At the beginning, I explored the method of its synthesis, tried all kinds of things, and went through twists and turns. However, after unremitting research, I finally got to optimize the path and improve the yield and purity.
Then, its physicochemical properties were observed, its stability and reactivity were revealed, and under specific conditions, it showed unique properties, laying the foundation for application.
As for application expansion, in the field of medicine, it is expected to become a new type of drug intermediate. After testing, it has the effect of inhibiting specific bacteria. In material science, it can participate in the preparation of special materials to increase its performance.
I firmly believe that with time, 3 - Fluorobenzenesulfonamide will be able to shine in many fields and promote the progress of the industry. This is the expectation of my research and the direction of unremitting progress.
Toxicity Research
Today there is a thing called 3-Fluorobenzenesulfonamide, and we want to study toxicology. Examine this substance in detail, how its properties are, and the toxicities involved.
Observe its chemical structure, molecular properties, or hidden toxicogenic causes. In the body, it may disturb the biochemical process and disrupt the order of cells. In order to understand its toxicity, try it on all living beings. Observe the changes in physiological characteristics after its intake, such as the reduction of vitality and the damage to organs.
After many tests, it gradually becomes clear that its toxicity. Or the decline of the body's function, which affects the nervous system, digestion and other systems. This toxicological study is crucial in order to prevent its harm and make use of it. It is necessary to deal with it cautiously and explore the root cause of its poison before formulating policies to preserve the safety of life and avoid disasters.
Future Prospects
In the future, it can be used to improve the field of medicine. With its characteristics, it may be able to develop new agents to cure difficult diseases and solve people's diseases. In the exploration of materials, there are also opportunities. Through ingenious research, it may be able to create new materials, which can meet the needs of diversity and help the rise of industry.
The road of scientific research is long, but our generation should have a strong heart and explore its endless mysteries. With time and good carving, we will be able to make it shine, seek well-being for future generations, and become a bright star for future development. This is our vision for its future.
Where to Buy 3-Fluorobenzenesulfonamide in China?
As a trusted 3-Fluorobenzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Fluorobenzenesulfonamide?
3-Fluorobenzenesulfonamide has a wide range of uses. In the field of medicine, it is often a key raw material for the creation of new drugs. Due to its unique chemical structure, it can interact with specific biological targets, so it is widely used in the development of antibacterial, anti-inflammatory and anti-tumor drugs. Medicinal chemists use it to modify drug molecules to improve drug activity, selectivity and bioavailability.
In the field of materials science, 3-fluorobenzenesulfonamide also has important uses. It can be used as a functional additive to improve the properties of polymer materials. For example, adding specific polymers can enhance the stability, wear resistance and corrosion resistance of materials. This property makes it very popular in the production of materials such as coatings, plastics and fibers. The improved materials have better performance and a wider range of application scenarios.
Furthermore, in the field of organic synthesis, 3-fluorobenzenesulfonamide is an extremely important intermediate. With its active chemical properties, it can participate in many organic reactions to construct complex organic molecular structures. Organic synthesis chemists use it to synthesize various organic compounds with special structures and functions, providing important support for the creation of new materials, pesticides and fine chemicals.
In the research and development of pesticides, 3-fluorobenzenesulfonamide also plays a role. By modifying its structure, pesticide varieties with high-efficiency insecticidal, bactericidal or herbicidal activities can be created. Such pesticides can not only effectively prevent and control crop diseases and pests, but also reduce the adverse impact on the environment and help the sustainable development of agriculture.
In summary, 3-fluorobenzenesulfonamide has important uses in many fields such as medicine, materials, organic synthesis and pesticides, and is of great significance to promote technological progress and industrial development in various fields.
What are the physical properties of 3-Fluorobenzenesulfonamide?
3-Fluorobenzenesulfonamide is a kind of organic compound. Its physical properties are as follows:
Looking at its appearance, under room temperature and pressure, it is mostly white to off-white crystalline powder, which makes it easier to handle and weigh in many operations. As for the color, it is white and pure, and the off-white is also close to pure white. This pure color may suggest its higher purity.
When it comes to the melting point, it is usually between 104 and 108 degrees Celsius. The melting point is one of the important physical constants of a substance. This specific melting point range can be used to identify the compound and is also a key indicator of its change during heating. When the temperature rises to this range, 3-fluorobenzenesulfonamide gradually converts from a solid state to a liquid state. This phase transition process is of great significance for its applications in chemical production, material preparation and other fields.
Its solubility is also an important physical property. 3-fluorobenzenesulfonamide is slightly soluble in water, but it exhibits good solubility in organic solvents such as ethanol and acetone. This property makes it widely used in the field of organic synthesis. Researchers can choose suitable solvents to achieve specific reactions or perform separation and purification operations based on its solubility. The good solubility in organic solvents such as ethanol and acetone provides convenient conditions for its participation in various organic reactions, which greatly expands its application scope in organic synthesis chemistry.
Furthermore, 3-fluorobenzenesulfonamide has certain stability, and its chemical structure and properties can be maintained relatively stable under conventional storage conditions. However, it should be noted that although its stability is acceptable, it should still avoid contact with strong oxidants, strong bases and other substances to prevent chemical reactions from occurring and causing their properties to change. This stability feature provides certain convenience for its storage and transportation process. As long as it follows the basic storage requirements, it can ensure that its quality is not too affected.
In summary, the physical properties of 3-fluorobenzenesulfonamide, such as appearance, melting point, solubility and stability, play a crucial role in its applications in many fields such as chemical engineering, medicine, and materials.
What are 3-Fluorobenzenesulfonamide synthesis methods?
The synthesis of 3-fluorobenzenesulfonamide has been known for a long time, and is described in detail below.
First, 3-fluorobenzenesulfonamide is used as the starting material. First, 3-fluorobenzenesulfonamide is mixed with concentrated sulfuric acid and slowly heated to cause a sulfonation reaction between the two. This process requires careful control of temperature and reaction time to prevent overreaction. After the reaction is completed, the reaction mixture is cooled to obtain 3-fluorobenzenesulfonate. Subsequently, this sulfate is reacted with sodium nitrite at low temperature to form a diazonium salt. This diazonium salt is extremely unstable and needs to be reacted with sodium sulfite immediately to convert it into sodium 3-fluorobenzenesulfonate. Finally, 3-fluorobenzenesulfonate can be obtained by treating sodium 3-fluorobenzenesulfonate with acid.
Second, 3-fluorobenzene is used as the starting material. The 3-fluorobenzene is reacted with magnesium chips in anhydrous ether to form a Grignard reagent. The Grignard reagent reacts with sulfur dioxide gas to generate 3-fluorobenzenesulfonate magnesium salt. After that, it is oxidized to 3-fluorobenzenesulfonate with an appropriate oxidizing agent, and then acidified to obtain 3-fluorobenzenesulfonamide.
Third, 3-fluorobenzoic acid is used as the starting material. First, 3-fluorobenzoic acid is converted into 3-fluorobenzoyl chloride, which can be achieved by reacting with thionyl chloride. Then 3-fluorobenzoyl chloride is reacted with thiourea to form an intermediate. After a series of reactions such as hydrolysis, 3-fluorobenzenesulfonamide can finally be obtained.
The synthesis method has its own advantages and disadvantages. It is necessary to choose carefully according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity of the product.
What is the price range of 3-Fluorobenzenesulfonamide in the market?
The price range of 3-fluorobenzenesulfonamide in the market is difficult to determine quickly. This is because the price of chemical products is often influenced by many factors.
The first to bear the brunt is the cost of raw materials. The preparation of 3-fluorobenzenesulfonamide requires specific starting materials. The fluctuation of raw material prices is directly related to product costs. If raw materials are scarce or supply channels change, the price will change. For example, if the price of fluoride raw materials required for preparation rises due to production reduction in the place of origin, the cost of 3-fluorobenzenesulfonamide will also increase, which in turn will cause its market price to fluctuate.
Furthermore, the trend of market supply and demand is also key. If the demand for 3-fluorobenzenesulfonamide increases sharply at some point, such as the development of new formulas in the pharmaceutical, pesticide and other industries, the dosage of it will rise sharply, and the supply will be difficult for a while, and the price will rise. On the contrary, if the demand is low, the manufacturer may reduce the price in order to reduce the inventory.
The production process and technical level also affect the price. Advanced technology can improve production efficiency, reduce energy consumption, and improve product purity, but the research and development and application of advanced technology require a huge investment. If the manufacturer adopts high-end technology, the product cost may be high, and the price will also increase accordingly; while the technology is backward, although the cost may be low, the product quality may not be sufficient, and the price is also limited.
In addition, regional factors should not be underestimated The price of 3-fluorobenzenesulfonamide varies in different places due to transportation costs, tax policies, and degree of market competition. Such as remote places, where transportation costs are high, the price may be higher than that in areas with convenient transportation.
Overall, the price range of 3-fluorobenzenesulfonamide in the market may vary from time to time and from place to place, ranging from tens of yuan per kilogram to hundreds of yuan. It is difficult to determine a fixed price range.
What are 3-Fluorobenzenesulfonamide storage conditions?
3-Fluorobenzenesulfonamide is one of the organic compounds. The key to its storage is related to the stability and effectiveness of this substance.
Store this 3-fluorobenzenesulfonamide, the first choice of its device. It is appropriate to use a sealed capacity, such as a glass bottle or a plastic bottle with a tight lid. Because the sealed device can prevent external moisture, air, etc. from disturbing. If exposed to humid air, or cause hydrolysis, damage its quality.
For the second time, the storage place is also important. When placed in a cool and dry place, avoid direct sunlight. Heat and light can both promote its transformation. Under high temperature, the reaction speed, or cause decomposition; light can also be the temptation of the reaction, damage its structure. Therefore, it is suitable for dark and warm storage to ensure its stability.
In addition, it is also necessary to be separated from other objects. Do not coexist with strong oxidizing substances or strong acid and alkali agents. Cover the properties of 3-fluorobenzenesulfonamide, or react with stains, and it is dangerous. If it encounters strong oxidation, or the risk of explosion; if it encounters with acid and alkali, or the reaction is initiated, change its quality.
Also, it should always be checked whether its contents are complete during storage. If there is a leak, move the other device and place the leak to prevent it from being scattered in the four, causing contamination and risk.
In general, when storing 3-fluorobenzenesulfonamide, it is necessary to use a sealed device to dry it and avoid light, avoid other dangerous objects, and check its device frequently, so as to ensure the quality of this object for later use.