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3-Fluorobenzeneboronic Acid

3-Fluorobenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

705065

Name 3-Fluorobenzeneboronic Acid
Molecular Formula C6H6BFO2
Molecular Weight 139.92 g/mol
Appearance White to off - white solid
Melting Point 158 - 162 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Pka Around 8.8
Density 1.24 g/cm³
Flash Point 119.8 °C
Cas Number 88283-99-0

As an accredited 3-Fluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluorobenzeneboronic Acid packaged in a sealed, chemical - resistant container.
Storage 3 - Fluorobenzeneboronic acid should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could lead to degradation. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid potential chemical reactions.
Shipping 3 - Fluorobenzeneboronic acid is shipped in well - sealed, corrosion - resistant containers. These are carefully packaged to prevent breakage and leakage during transit, following strict chemical shipping regulations.
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3-Fluorobenzeneboronic Acid 3-Fluorobenzeneboronic Acid
General Information
Historical Development
3-Fluorophenylboronic acid, the rise of its materials, has been around for a long time. In the past, all the masters were in the field of organic synthesis, diligently researching and unremitting, wanting to obtain new agents, in order to expand the road of chemical industry.
At the beginning, the preparation method was still simple, but the yield was quite low, and there were many impurities, which was difficult to use. Later, through the ingenuity of all workers and the improvement of skills, the yield and purity gradually increased.
In recent times, science and technology have advanced day by day, and new techniques have emerged one after another. The developers have used advanced instruments to fine-analyze the reaction mechanism and optimize the process. In catalysis and solvents, they have made pioneering achievements. The production of 3-fluorophenylboronic acid is not only abundant, but also of high quality. It is widely used in medicine, materials and other industries, contributing to the rise of industry. Its past evolution is also a model for future generations to develop new things.
Product Overview
Today there is a product called 3 - Fluorobenzeneboronic Acid. Its color is pure and pure, and it is a white powder. This is a key raw material for organic synthesis and is of great use in the fields of medicinal chemistry and materials science.
Looking at its molecular structure, fluorine atoms are cleverly connected to benzene rings, and boric acid groups formed by boron atoms give this product unique chemical activity. With this activity, it can participate in a variety of coupling reactions, such as Suzuki - Miyaura coupling, to build complex organic molecular structures.
In the process of pharmaceutical research and development, it can help create new drugs or optimize the performance of existing drugs. In the field of materials science, it can also contribute to the synthesis of materials with specific optical and electrical properties. Therefore, 3-Fluorobenzeneboronic Acid is an indispensable material in the field of chemical research.
Physical & Chemical Properties
3-Fluorophenylboronic acid, its physical and chemical properties can be studied. Looking at its shape, it is often white to light yellow powder, which can be seen from the eye, which is a sign of its appearance. Its melting point is fixed, about 145-149 ℃. When heated to this point, the state of matter gradually changes, which is thermal.
In terms of solubility, it is slightly soluble in water, and in organic solvents, such as ethanol and ether, it is slightly soluble, which is related to the intermolecular force and solvent characteristics. Its chemical activity is also worth noting. The existence of boron atoms makes this substance a key reagent in the field of organic synthesis, capable of reacting with many compounds to form new structures, and contributing greatly to the development of organic synthetic chemistry. Studying the properties of this substance can provide assistance for the progress of chemical, pharmaceutical and other industries, and exploring its mysteries is also a priority for our chemical researchers.
Technical Specifications & Labeling
There are 3 - Fluorobenzeneboronic Acid today, which is very important in my chemical research. Its technical specifications and identification (product parameters) need to be studied in detail.
Looking at its technical specifications, the purity must be excellent, and the impurities need to be few and few, in order to be suitable for all kinds of uses. Its physical properties, such as color state, melting point, boiling point, etc., are all suitable for specific standards. And the synthesis method also needs to be accurate. From the selection of raw materials to the control of reactions, it is all related to the quality of the product.
As for the identification (product parameters), the ingredient identification must be clear, and the proportion of each substance contained must be clearly identifiable. Safety signs should not be ignored, indicating possible dangers, so as to warn everyone to deal with them properly. In this way, 3 - Fluorobenzeneboronic Acid can be used in various applications to show its ability without worry.
Preparation Method
The raw materials and production process are the key to the method of making 3-Fluorobenzeneboronic Acid. First, fluorobenzene is taken as the starting material, supplemented by borate ester, and palladium as the catalyst. Under suitable temperature and pressure, the Suzuki reaction is carried out. The steps are as follows: First, fluorobenzene, borate ester, palladium catalyst and alkali are co-placed in the reactor according to a specific ratio. Then nitrogen is used to remove the oxygen in the kettle to avoid side reactions. Warm up to about 100-120 degrees Celsius and continue to stir to make the reaction sufficient. After the reaction is completed, the product is purified by extraction, distillation and other methods. The catalytic mechanism of this process is that palladium complexes with the reactants first, promotes the breaking and recombination of its bonds, reduces the energy barrier of the reaction, and increases the reaction rate. In this way, 3-Fluorobenzeneboronic Acid can be prepared efficiently, and the yield is quite good, and the purity is also required.
Chemical Reactions & Modifications
Taste the wonders of chemistry, related to the change of substances, reaction and modification are particularly important. In this sentence, 3-Fluorobenzeneboronic Acid is worth exploring its chemical reaction.
In the process of reaction, it is often complemented by various reagents to rearrange the molecular structure, and the properties are easier. If it encounters nucleophiles, it can lead to changes in the specificity of check point and form new compounds, and its activity may be increased or damaged.
Modification, or adjust its acid-base properties, or change its spatial structure. After modification, 3-Fluorobenzeneboronic Acid may have better performance in the field of catalysis, which can promote the speed of reaction and improve the purity of the product.
Looking at its reaction and modification, it is like a skilled craftsman carving beautiful jade, which makes the material glow with a different brilliance. It has extraordinary potential in the chemical industry, medicine and other industries. It will be further studied by our generation to uncover more mysteries.
Synonyms & Product Names
3-Fluorophenylboronic acid, this substance is quite useful in chemical research. Its synonyms and trade names also need to be explored in detail. "3-Fluorobenzeneboronic Acid", this is its English name, and in China, there are also many other names. Or fluoroborophenylboronic acid, or the name of boroborophenylboronic acid, all of which refer to this substance.
The name of its product is also different from that of various trade names. Or it gets different names because of its purity and production method. Some are called high-purity fluoroborophenylboronic acid, emphasizing its high purity; others are called special boroborophenylborophenylboronic acid, highlighting the uniqueness of the production method.
Chemical researchers, when exploring this material, should carefully examine its heteronym and trade name. Because of different names, or related to different qualities and uses. Only by knowing its name can we make good use of this material and go far in the road of chemical research.
Safety & Operational Standards
3-Fluorophenylboronic acid safety and operation specifications
3-Fluorophenylboronic acid is also a commonly used item in chemical research. If you want to make good use of it, you must understand its safety and operation specifications, so as to ensure that everything goes smoothly and there is no danger of danger.
#1. Storage
Store in a cool, dry and well-ventilated place, away from fire and heat sources. It must be stored separately from oxidizing agents, strong alkalis and other foreign substances, and must not be mixed to prevent disasters. The container must be sealed to avoid contact with moisture and change.
#2. Operating rules
When operating, when operating in a well-ventilated environment, and with suitable protective equipment. Never let the skin and eyes come into contact with it. If you accidentally touch it, the skin should be rinsed with a lot of water quickly, and then seek medical attention according to the situation; if you have eyes, immediately open the eyelids and rinse with flowing water or normal saline, and you must also seek medical help urgently. It is strictly forbidden to eat, drink and smoke in the operation room to prevent accidental entry into the mouth and endangering life.
#3. Emergency response
If there is a leak, the first thing to do is to evacuate everyone, isolate the scene, and strictly prohibit unrelated people from approaching. Emergency responders must wear protective equipment, carefully collect leaks in clean, covered containers, and then properly dispose of them. Small leaks can be adsorbed by inert substances such as sand and vermiculite; if there are large leaks, you need to build embankments to contain them, and then ask professional personnel to deal with them.
#Fourth, the method of discarding
Discarded 3-fluorophenylboronic acid must be handed over to a qualified institution in accordance with relevant laws and regulations. Do not discard at will to avoid polluting the environment and harming life.
In short, in the research and application of 3-fluorophenylboronic acid, safety is the priority, and the operation is in accordance with regulations, so as to ensure people's safety and Wutai, and the road to scientific research is smooth.
Application Area
Today there is a thing called 3 - Fluorobenzeneboronic Acid, which has wonderful uses in many fields. In the way of medicine, it can help the synthesis of pharmaceuticals to treat various diseases. Or as a key raw material, participate in the creation of wonderful medicines, make the efficacy of medicines better, and heal patients. In the field of materials, it also has its function. It can be the cornerstone of building special materials, making the materials have extraordinary properties, such as better conductivity, heat resistance, etc., suitable for high-tech products. And in the field of organic synthesis, it can be a bridge of reactions, leading to the formation of new compounds, and expanding the boundaries of the chemical world. From this perspective, this substance plays a pivotal role in the application fields of medicine, materials, and organic synthesis, and it is indeed something that cannot be underestimated.
Research & Development
In recent years, I have studied many chemical substances, especially 3-Fluorobenzeneboronic Acid. Its effectiveness in the field of organic synthesis is quite obvious. At the beginning, I wanted to get this product, but the preparation method was not good, the yield was not high, and there were many impurities. We have tried our best to search the classics and try all kinds of methods. Or change the reaction conditions, adjust the temperature and pressure; or easy to use reagents, seek its purity. After months of work, I have gradually achieved success. The yield is gradually increasing, and the quality is also excellent. Looking at it today, this product is not only beneficial for the synthesis of new compounds, but also has broad prospects in the fields of pharmaceutical research and development, materials science, etc. We should continue to study and explore its potential, hoping to contribute to the development of chemistry and the progress of science and technology, so that it can be more widely used and benefit the world.
Toxicity Research
Yu Taste is committed to toxicological research, recently focusing on 3 - Fluorobenzeneboronic Acid. The study of toxicants is related to the safety of living beings and must be observed.
3 - Fluorobenzeneboronic Acid, the investigation of its toxicity needs to be fine and cautious. Initial observation of its properties, under specific conditions, or the risk of harm to the organism. From an experimental point of view, when applied to various test organisms, some showed abnormal physiological characteristics.
However, the depth of toxicity cannot be determined overnight. Different environments and doses can make their toxicity different. Or at high concentrations, the toxic effect is significant and biological functions are damaged; at low doses, only minor effects are seen, or hidden and difficult to detect.
We should use scientific methods to study its toxicity mechanism in detail, clarify its action pathway, and explore its harm boundary. For people's livelihood and ecological concerns, we will make unremitting research to ensure that the world knows its toxicity, prevent problems before they occur, and ensure the safety of all things.
Future Prospects
3 - Fluorobenzeneboronic Acid, it is also a matter of transformation. There are still many things to look forward to in the future.
This object is in the field of synthesis, or it can develop its extraordinary capabilities. Its unique properties, or it can be used as a new medium for reflection, so that the general synthesis path is convenient and efficient. In the way of research, it is also expected to become a raw material for the development of new technologies, so as to save the world's diseases.
And its application in the material science, or it can be used to improve the performance of high-performance materials, such as better performance and quality. In the future, researchers will explore in depth, or they will be able to explore a new world of applications, which will be as convenient as our lives. We can wait and see how it will be developed in the future.
Where to Buy 3-Fluorobenzeneboronic Acid in China?
As a trusted 3-Fluorobenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 3-fluorophenylboronic acid?
3-Bromobenzoic acid is an organic compound with unique chemical properties and a wide range of uses in many fields.
In terms of acidity, the carboxyl group confers the acidity of 3-bromobenzoic acid. The hydrogen atoms in the carboxyl group can be partially ionized, releasing hydrogen ions, thus exhibiting acidity. In water, it can neutralize with bases, such as with sodium hydroxide. The hydrogen ion in the carboxyl group combines with the hydroxide ion to form water, and itself forms a sodium salt of 3-bromobenzoate. This reaction reflects its acidic properties. In organic synthesis, this property is often used to prepare 3-bromobenzoate compounds, which are used for specific reactions or as intermediates.
From the perspective of substitution reaction, hydrogen atoms on the benzene ring have specific reactivity due to the influence of carboxyl groups and bromine atoms. Under appropriate conditions, electrophilic substitution reactions can occur on the benzene ring. For example, in the presence of suitable catalysts, halogenation reactions can occur with halogenating agents to introduce new halogen atoms at other positions in the benzene ring; nitrification reactions can also occur with nitrifying reagents to introduce nitro groups. This is because the carboxyl group is an electron-withdrawing group and the bromine atom is an ortho-para-site locator. The combined action of the two determines the density distribution of electron clouds at different positions on the benzene ring, which in turn affects the location and difficulty of electrophilic substitution reactions.
In addition, bromine atoms of 3-bromobenzoic acid can participate in a variety of It has certain reactivity, and under suitable reagents and conditions, nucleophilic substitution reactions can occur. For example, it can react with nucleophilic reagents containing hydroxyl groups and amino groups, and bromine atoms are replaced by nucleophilic reagents to generate corresponding compounds containing new functional groups. This reaction is crucial in building complex organic molecular structures. Through the transformation of bromine atoms, various functional groups can be introduced to expand the structure and function of compounds.
In some organic synthesis routes, 3-bromobenzoic acid can be used as a starting material. By virtue of its acidity, benzene ring substitution reaction and bromine atom reactivity, more complex and functional organic compounds can be gradually constructed, which play an important role in drug synthesis, materials science and other fields.
What are the main uses of 3-fluorophenylboronic acid?
3-Tyrosine acid, also known as L-dopa (L-DOPA), is an important biological compound. It is widely used in various domains such as food and food. It is as follows:
***:
Its main use is in the treatment of Parkinson's disease. Parkinson's disease is caused by the degeneration of dopaminergic energy in the black domain of the body, resulting in insufficient dopamine secretion. And 3-tyrosine tyrosine, as a direct precursor to dopamine, can improve the blood barrier. Once it is introduced into the body, it will reduce dopamine under the action of aromatic acid carboxylase, and reduce the deficiency of dopamine in patients. It can effectively improve the health of patients with Parkinson's disease, and greatly improve their quality of life.
** Food field **:
Some foods also add 3-tyramine acid, because it has certain health benefits. For example, it can improve mental function, or help people's health and improve their mood. For those who are depressed and sleep poorly due to high mental energy, foods containing 3-tyramine acid may have certain health effects. In addition, in some foods, 3-tyrosine acid is also useful. It can improve muscle strength and endurance, and help improve performance in terms of performance and performance.
** Research field **:
3-tyrosine acid is also an important tool in neuroscience research. By using 3-tyrosine acid, researchers can delve deeper into the physiological and pathological mechanisms of dopaminergic diseases. For example, in the study of the treatment of certain neurodegenerative diseases, 3-tyrosine acid is used to investigate its biological activity and treatment, and to provide a rationale for disease prevention and control strategies.
What are the synthesis methods of 3-fluorophenylboronic acid?
The synthesis method of 3-bromobenzoic acid is not directly described in the ancient book "Tiangong Kaiwu", but according to the ancient chemical process principle and related books, the method may be obtained.
First, using benzoic acid as the starting material, the method of bromination can be obtained. Under the conditions of ancient chemical experiments, benzoic acid can be prepared first and placed in ceramic vessels. Sulfur and saltpeter are mixed in appropriate proportions to make a combustion aid and heat the pottery. When the benzoic acid is slightly melted, bromine is slowly added. Bromine can be extracted from seawater and purified by distillation. In this process, the reaction phenomenon is closely observed, and the control of the temperature is the most important. In ancient chemical processes, the control of the temperature is about success or failure. Under appropriate conditions, benzoic acid and bromine can be substituted to form 3-bromobenzoic acid. This reaction may require multiple attempts to find the best ratio and reaction time.
Second, starting from toluene, nitrate is first prepared from m-nitrotoluene. The ancient production of nitrate is mostly derived from saltpeter. Mix saltpeter, charcoal, and sulfur in a certain proportion and heat the reaction to obtain nitric acid. React with nitric acid and toluene to obtain m-nitrotoluene. Then, the m-nitrotoluene is reduced to m-amino toluene. The ancient reduction method may use iron powder and hydrochloric acid to react at a suitable temperature. After diazotization and bromination, 3-bromobenzoic acid can be finally prepared. There are many steps in this process, but each step has its own method. In the process of diazotization, it is necessary to precisely control the temperature and the ratio of reagents to prevent the reaction from getting out of control. When bromiding, it is also necessary to pay attention to the amount of bromine and the reaction environment.
Third, 3-bromobenzoic acid is obtained by oxidation of m-bromotoluene as raw material. In the ancient oxidation method, a strong oxidant such as potassium permanganate can be selected. Put m-bromotoluene and potassium permanganate in water, heat and stir. For potassium permanganate, it can be obtained in the mine veins in the mountains, and it can be used after refining and purification. During the reaction process, pay attention to adjusting the pH of the solution to promote the oxidation reaction. After the reaction, after separation and purification, pure 3-bromobenzoic acid can be obtained. Purification method, or recrystallization, water or appropriate organic solvent, multiple crystallization, can improve the purity of the product.
What are the precautions for 3-fluorophenylboronic acid during storage and transportation?
During the storage and transportation of 3-hydroxybutyric acid, many key matters need to be paid attention to.
When it is stored, the first priority is the environment. When it is suitable to be in a cool, dry and well-ventilated place, it must not be placed in direct sunlight or in a place with severe temperature fluctuations. Because the temperature is too high, or 3-hydroxybutyric acid is chemically reacted, causing its properties to change. As "Tiangong Kaiwu" said, "everything has its own nature, and it will exist if it goes along with it, and it will die if it goes against it." 3-hydroxybutyric acid also has its own "nature", and this environment will go along with it.
Furthermore, storage containers are essential. It is necessary to use a corrosion-resistant and well-sealed container to prevent 3-hydroxybutyric acid from leaking or reacting with external substances. I still remember that the ancients stored medicine and chose excellent tools to ensure the efficacy of the medicine. The same is true.
As for the transportation, be sure to ensure that the packaging is firm. "A journey of a thousand miles begins with a single step". Stable packaging is the foundation of transportation safety. The means of transportation must be clean and free of other substances that may react with it. During driving, the speed is smooth, avoid bumps and vibrations, and avoid damage to the packaging.
In addition, relevant personnel must have a detailed understanding of the characteristics of 3-hydroxybutyric acid. Know its chemical properties, and in case of emergencies, you can know how to deal with it properly. For example, when the ancients boated, they were familiar with water-based transportation to ensure stable navigation, and when transporting 3-hydroxybutyric acid, they also needed to be familiar with its properties, so that the storage and transportation process could be safe and secure, and the quality of 3-hydroxybutyric acid would not be affected.
What is the market price range of 3-fluorophenylboronic acid?
3-Pentenobutyric acid is an organic compound that is used in many fields such as chemicals, pharmaceuticals, and fragrances. Its market price is determined by many factors such as raw material cost, production process, market supply and demand, and fluctuates frequently, and varies depending on quality, purity, trading area, and trading time.
There is no exact public data to clarify its specific price range. If you want to know its market price roughly, you can use the following channels: First, chemical product trading platforms. Many online chemical product trading platforms will list the quotations of various chemicals. You can log in to such platforms to find the price information of 3-Pentenobutyric acid according to product specifications, purity and other parameters. However, you need to pay attention to the differences in quotations from different merchants, and the price may fluctuate with the market. Second, chemical raw material suppliers. Directly contact chemical raw material suppliers to inquire about the price of 3-pentylbutyric acid, and the supplier will provide corresponding quotations according to factors such as demand quantity, delivery location, payment method, etc. Third, industry exhibitions and seminars. Exhibitions and seminars in the chemical industry bring together many enterprises and professionals, where you can communicate with relevant practitioners to obtain information such as the market price of 3-pentylbutyric acid.
In short, due to the dynamic changes in the market, the market price of 3-pentylbutyric acid is difficult to generalize. It is necessary to go through the above multiple channels and combine the specific transaction situation to obtain a relatively accurate price range.