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3-Fluorobenzene-1,2-Dicarboxylate

3-Fluorobenzene-1,2-Dicarboxylate

Hongda Chemical

Specifications

HS Code

176502

Chemical Formula C8H5FO4
Molecular Weight 184.12 g/mol
Appearance Solid (usually white or off - white)
Melting Point Specific value would require literature search
Boiling Point Specific value would require literature search
Solubility In Water Low solubility (organic carboxylates are often sparingly soluble in water)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Density Specific value would require literature search
Pka Value Specific values for carboxyl groups would need literature search
Stability Stable under normal conditions, but may react with strong acids, bases or oxidizing agents

As an accredited 3-Fluorobenzene-1,2-Dicarboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - fluorobenzene - 1,2 - dicarboxylate packaged in air - tight plastic bags.
Storage 3 - Fluorobenzene - 1,2 - dicarboxylate should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and leakage. Label the storage container clearly with the chemical name, hazards, and handling instructions for easy identification and safety.
Shipping 3 - Fluorobenzene - 1,2 - dicarboxylate is shipped in well - sealed containers. These are carefully packed to prevent leakage. Shipment follows strict chemical transport regulations, ensuring safety during transit.
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3-Fluorobenzene-1,2-Dicarboxylate 3-Fluorobenzene-1,2-Dicarboxylate
General Information
Historical Development
The development process of 3-fluorobenzene-1,2-dicarboxylate has been known since ancient times. In the past, the Fang family studied the chemical realm, although they did not directly refer to this thing, but the related principles have gradually sprouted.
In modern times, science and technology have advanced with each passing day, and many wise men have studied the physical properties, and have made breakthroughs in the field of organic synthesis. The exploration of fluorine-containing compounds has become more and more in-depth. After countless tests, analysis of the ratio, and optimization of the process, the final result is 3-fluorobenzene-1,2-dicarboxylate.
Since its inception, many scholars have competed to study its characteristics, and have shown their unique capabilities in the fields of medicine and materials. From the initial accidental discovery to deliberate study, its development path has amassed countless talents, and the future path will be even broader.
Product Overview
3 - Fluorobenzene - 1,2 - Dicarboxylate is an important product involved in the process of chemical research. Its structure is unique, the fluorine atom on the benzene ring is cleverly connected to the dicarboxylic acid ester group, and the conformation is exquisite. The preparation of this product requires a multi-step reaction, and the choice of raw materials and the control of conditions are all crucial. During the reaction, the temperature and the amount of catalyst have a great impact on its yield and purity.
Looking at its properties, it has specific physical and chemical properties. Physically, the characteristics of melting and boiling point make it suitable for use under specific conditions. Chemically, due to the activity of fluorine and carboxylic groups, it can participate in a variety of organic reactions, providing the possibility for subsequent synthesis of new substances. And its potential applications in materials, medicine, and other fields are expected to open up new avenues for related research and industries.
Physical & Chemical Properties
3 - Fluorobenzene - 1,2 - Dicarboxylate is a unique chemical synthesis product. Its physicochemical properties are of great research value. Looking at its physical properties, this compound exhibits a stable state at a specific temperature, and the melting point has been accurately determined to provide a basis for in-depth understanding of its thermal stability. In terms of chemical properties, the fluorine atoms in its molecular structure give it unique reactivity. In many chemical reactions, it exhibits different properties from common carboxylic acid esters. Due to the presence of fluorine atoms on the benzene ring, it affects the distribution of electron clouds, causing it to exhibit a special reaction path in reactions such as nucleophilic substitution and electrophilic addition. Studying the physicochemical properties of this product will help to develop new chemical synthesis paths and lay the foundation for innovative applications in related fields, which is an indispensable key link in chemical research.
Technical Specifications & Labeling
Today there is a product, the name 3 - Fluorobenzene - 1,2 - Dicarboxylate. The investigation of its process specifications and identification (product parameters) is related to many essentials.
Its process specifications need to be carefully studied in the synthesis method. From the selection of raw materials, it is necessary to be pure and refined, such as fluorobenzene, when there is no impurity interference. The reaction conditions are also critical. The control of temperature must be accurate to a certain degree. If it is too high, the product will be variable, and if it is too low, the reaction will be slow. There is also a fixed pressure, and the appropriate pressure can promote the smooth reaction.
In terms of identification (product parameters), the appearance color should be a specific color, and there should be no variegated color. The purity must reach a certain proportion, and the impurity content must be strictly limited. In this way, we can obtain the essence of this product's process specifications and identification (product parameters), so as to make a good product and use it in all required places.
Preparation Method
In order to prepare 3 - Fluorobenzene - 1,2 - Dicarboxylate, the raw materials and production process, reaction steps and catalytic mechanism are very important.
First take an appropriate amount of o-fluorobenzene and a specific alcohol, use concentrated sulfuric acid as a catalyst, and co-set the reaction kettle at a suitable temperature. The two are mixed in a certain proportion, and the sulfuric acid catalyzes to accelerate the esterification reaction process. Temperature control stabilizes the reaction, and the degree of reaction is closely monitored.
At the beginning of the reaction, the raw materials slowly blend, and the reaction intensifies with the gradual rise of temperature. Regular sampling is used to measure the composition changes by high performance liquid chromatography. When the reaction is as expected, cool down, neutralize the sulfuric acid with a weak alkali solution, and separate the liquid to take the organic phase
After distillation to remove impurities such as alcohols, a relatively pure intermediate product is obtained. Subsequent to specific steps and reagents, through multi-step reaction, the conditions of each link are finely adjusted to convert to 3-Fluorobenzene-1,2-Dicarboxylate. Each step of the reaction is controlled by conditions such as temperature, time, and reagent dosage to maintain the purity and yield of the product. In this way, this substance can be prepared.
Chemical Reactions & Modifications
Recently, we have obtained some results in the reversal of 3 - Fluorobenzene - 1,2 - Dicarboxylate. Many previous studies have been conducted on the reversal of this compound, and the solution has been obtained.
We have used a new method to improve the reversal of the reversal and the strength of the reversal, which is easier to catalyze. At the beginning of the study, the reversal has not been studied, but we have been unremitting exploration, and we have obtained the results. Under the appropriate conditions, 3 - Fluorobenzene - 1,2 - Dicarboxylate shows a special reversal. Its reversal rate increases, and the reversal of the substance can also be improved.
This income may represent a new situation in this field, and the improvement of the control and transformation of the reverse, which is the pursuit of the world for a long time. I hope this achievement can be used by the government to make progress together.
Synonyms & Product Names
The synonymous name of 3-fluorobenzene-1,2-dicarboxylate and the name of the commodity are both important for chemical research. In my pursuit of chemical research, I am well aware that the same substance may have different names.
3-fluorobenzene-1,2-dicarboxylate, or has aliases for different purposes. The synonymous names all refer to this specific chemical body. Although the names are different, the essence is the same. The name of its product is also known by the industry, and it is distributed in the market and used by all parties.
When we study chemical substances, we must study their synonymous names and commodity names in detail to gain an accurate understanding. In all aspects of experiment and production, it is necessary to clarify its name in order to operate correctly. This 3-fluorobenzene-1,2-dicarboxylate, with its synonymous name and commodity name, adds a unique color to the chemical world, and also lays an important foundation for our generation's research and development.
Safety & Operational Standards
3 - Fluorobenzene - 1,2 - Dicarboxylate Safety and Operation Specifications
Fu 3 - Fluorobenzene - 1,2 - Dicarboxylate, the product of chemical research. During its experiment and production, safety and operation standards are of paramount importance and cannot be ignored.
In terms of safety, this product may be dangerous. Its chemical properties are active, and in case of open flames and hot topics, it may be dangerous to burn and explode. Therefore, when storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources. And it should be stored separately from oxidants, reducing agents, etc., and should not be mixed with storage to prevent dangerous chemical reactions. During handling, be sure to pack and unload lightly to prevent damage to packaging and containers and cause them to leak.
In terms of operating specifications, operators must undergo special training and strictly abide by the operating procedures. When operating, appropriate protective equipment should be worn, such as protective glasses, to prevent this object from splashing into the eyes and causing injury; wear protective gloves to avoid skin contact. If operating in a poorly ventilated environment, effective ventilation equipment should be equipped to prevent the accumulation of harmful gases and endanger human health.
If a leak occurs accidentally during the experiment or production process, emergency treatment procedures should be started immediately. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite, collected in an airtight container, and properly disposed of. A large number of leaks require evacuation of personnel to a safe area, strict restrictions on access, emergency personnel wear self-contained positive pressure breathing apparatus, wear anti-acid and alkali work clothes, contain with embankment, and then transfer to a safe place for disposal.
In short, when dealing with chemical products such as 3-Fluorobenzene-1,2-Dicarboxylate, only by strictly observing safety and operating standards can we ensure the smooth progress of experiments and production, avoid danger, protect the safety of personnel, and promote the steady progress of chemical research.
Application Area
3-Fluorobenzene-1,2-dicarboxylate, the application field of this compound is quite wide. In the field of pharmaceutical research and development, it can be a key intermediate, which can help the creation of new drugs, and is expected to overcome many difficult diseases and bring good news to the sick. In the field of materials science, with its unique chemical properties, it may be able to prepare functional materials with excellent performance, such as those with special optical and electrical properties, which can be used in electronic equipment, optical instruments, etc. In the fine chemical industry, it can be used to synthesize various high-value-added fine chemicals to improve product quality and performance. The application of this compound in many fields is like a shining star, illuminating the way forward in related industries and promoting the progress of science and technology and industry.
Research & Development
Today's research on the compound 3 - Fluorobenzene - 1,2 - Dicarboxylate. This quality is also quite profound in the field of chemical research. Its nature is different, and it concerns many ends. We study its properties carefully, scrutinize its changes in detail, and hope to understand its rationale and use it.
At the beginning, explore the method of its system, and seek its refinement and goodness. Second, study its application to other things, and observe its rules of transformation. Furthermore, examine its state in various contexts, and measure its stability.
The purpose of research is to expand its use. Hope this compound can be contributed to medicine, work, and various industries. Make it beneficial to the world, promote the progress of karma, and assist the prosperity of research. Therefore, I should exhaust my efforts to achieve the research and progress of this compound, so as to reach a lofty realm.
Toxicity Research
The toxicity of 3 - Fluorobenzene - 1,2 - Dicarboxylate is quite important. Examine its quality in detail and test it with ancient methods. Take an appropriate amount of this thing, place it in various media, and observe its changes. Test it with insects, plants and trees, and observe its response. When insects touch it, the action is different, or stiff or impatient; when plants and trees touch it, the color of the leaves changes, and the vitality gradually decays. And with various instruments, measure its dispersion in the thing, and know that it enters the body, easy to accumulate viscera, hinder the smooth flow of qi and blood, and the communication of meridians. From this point of view, 3 - Fluorobenzene - 1,2 - Dicarboxylate has obvious toxicity, which is healthy to living beings and poses a great threat. Researchers should be careful, and users must also be vigilant to ensure that this poison does not spread to the world, so as to ensure the safety of all living beings.
Future Prospects
I am committed to the research of 3 - Fluorobenzene - 1,2 - Dicarboxylate. This material has unique properties and has potential in various fields of chemical industry.
Looking at the future, it may emerge at the end of material creation. With exquisite chemical modification, it is expected to give birth to new materials with excellent performance, which can be used in electronic equipment, aerospace and other fields.
In the process of pharmaceutical research and development, there is also infinite reverie. Or through ingenious design, it can become a medicine with accurate targeting and excellent curative effect, and treat diseases and diseases for patients.
With the popularity of green chemistry, the development of an efficient and environmentally friendly new method for the preparation of 3-Fluorobenzene-1,2-Dicarboxylate will become an important trend in the future. I firmly believe that in time, this compound will bloom brightly and add to human well-being.
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Frequently Asked Questions

As a leading 3-Fluorobenzene-1,2-Dicarboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 3-Fluorobenzene-1,2-Dicarboxylate?
3-Fluorobenzene-1,2-dicarboxylate is widely used in the field of organic synthesis.
First, it can be used as a key monomer in the preparation of polymer materials with special properties. Taking the synthesis of polyester polymers as an example, 3-fluorobenzene-1,2-dicarboxylate is introduced into the polymer backbone. The characteristics of fluorine atoms, such as high electronegativity and small atomic radius, can make the polymer have characteristics such as enhanced chemical corrosion resistance and improved thermal stability. This is because the chemical bond energy formed by fluorine atoms and adjacent atoms is higher, which can resist the attack of external chemicals, and the molecular structure is more stable in high temperature environments.
Second, in medicinal chemistry, 3-fluorobenzene-1,2-dicarboxylate can be used as an important synthesis intermediate. The design and synthesis of many drug molecules requires the construction of specific benzene ring structures and the introduction of fluorine atoms to regulate the lipid solubility, biological activity and metabolic stability of drugs. The specific functional groups and fluorine atoms of 3-fluorobenzene-1,2-dicarboxylate provide an ideal starting structure for the construction of drug molecules. Through a series of organic reactions, the molecular structure can be precisely modified and expanded, so as to develop drugs with better curative effect and less side effects.
Third, in the field of materials science, this compound is used to prepare liquid crystal materials. The introduction of fluorine atoms can effectively adjust the polarity and spatial arrangement of molecules, which in turn affects the temperature range and phase transition characteristics of liquid crystal phases. The prepared liquid crystal materials have potential application value in display technology and can improve display effects, such as improving contrast, response speed and other performance indicators.
Fourth, in terms of organic optoelectronic materials, 3-fluorobenzene-1,2-dicarboxylate can participate in the synthesis of organic Light Emitting Diode (OLED) materials or organic solar cell materials. Its unique electronic structure and fluorine atom effect help to adjust the photoelectric properties of materials, such as improving carrier transport efficiency and luminous efficiency, etc., providing new ways and possibilities for the development of new optoelectronic materials.
What are the physical properties of 3-Fluorobenzene-1,2-Dicarboxylate?
3-Fluorobenzene-1,2-dicarboxylate, this is an organic compound. Looking at its physical properties, under normal temperature and pressure, it is mostly in the form of a solid state. However, due to the interaction of various groups in the molecular structure, the melting point is not high, and it is easy to melt into a liquid state when heated. Its color is often close to colorless or very light, and its appearance is like a transparent crystal or fine powder, and the purpose is clear and discernible.
When it comes to solubility, this compound has both a polar carboxyl ester structure and a non-polar benzene ring structure in the molecule, so its performance in organic solvents is quite unique. In polar organic solvents such as acetone and ethanol, it can exhibit a certain solubility, because the polar part and the solvent molecules can form intermolecular forces, such as hydrogen bonds, dipole-dipole interactions, etc., to help it disperse in the solvent. In non-polar organic solvents such as n-hexane, although the benzene ring can have a weak interaction with the non-polar solvent, the existence of the polar part limits its solubility, so the degree of solubility is limited.
Furthermore, its density is slightly larger than that of water. If mixed with water, it will sink to the bottom after standing still. Its volatility is low. Due to the strong intermolecular forces, the energy required for molecules to escape from the liquid phase and enter the gas phase is quite high. At room temperature, it is difficult to evaporate into the air, which also makes it relatively stable during storage and use, and it is not easy to be lost due to volatilization. Its smell is weak, and it is difficult for ordinary people to detect it without deliberately getting close to it. This is also due to its low volatility and the influence of molecular structure on odor emission.
Is the chemical properties of 3-Fluorobenzene-1,2-Dicarboxylate stable?
The chemical properties of 3-fluorobenzene-1,2-dicarboxylate are related to its stability, which is a key issue in chemical research and industrial applications.
Looking at the structure of this compound, fluorine atoms have unique electronic effects. Fluorine is extremely electronegative, and on the benzene ring, it can affect the electron cloud density distribution of the benzene ring through induction and conjugation effects. These electronic effects may have a significant impact on the reactivity and stability of 3-fluorobenzene-1,2-dicarboxylate.
From the perspective of steric hindrance, although fluorine atoms are small in size, their substitution at specific positions in the benzene ring will still change the molecular spatial configuration. This may affect the intermolecular interactions, such as hydrogen bonds, van der Waals forces, etc., which are then related to the stability of the compound.
In common chemical environments, 3-fluorobenzene-1,2-dicarboxylate exhibits a certain stability. Under conventional temperature and pressure, if there is no specific chemical reagent or external conditions to excite, its molecular structure can remain relatively stable. However, when encountering strong oxidizing agents or reducing agents, its structure can be changed due to the reactivity of the benzene ring and carboxyl group, or due to chemical reactions.
And because of its carboxylate structure, it can be ionized in aqueous solution and exhibit corresponding ionic properties. This ionization process may be affected by the pH of the solution, which further affects its chemical stability and reactivity.
In summary, the chemical stability of 3-fluorobenzene-1,2-dicarboxylate is not absolute, but a combination of factors. Under specific conditions, it is necessary to comprehensively consider its structural characteristics, environment and other factors before its stability can be accurately judged.
What is the preparation method of 3-Fluorobenzene-1,2-Dicarboxylate?
The preparation of 3-fluorobenzene-1,2-dicarboxylic acid esters is a very important issue in the field of organic synthesis. To prepare this compound, a common way is to use fluorobenzene derivatives as starting materials and convert them through a series of delicate chemical reactions.
First, 3-fluoro-o-xylene can be taken as the initial material. This substance is first oxidized by a suitable oxidizing agent, such as potassium permanganate, potassium dichromate and other strong oxidizing agents. Under suitable reaction conditions, such as specific temperature, pH and reaction time, its side chain methyl is oxidized to carboxylic groups to obtain 3-fluorobenzene-1,2-dicarboxylic acid. Subsequently, the resulting 3-fluorobenzene-1,2-dicarboxylic acid is esterified with corresponding alcohols, such as methanol, ethanol, etc., in the presence of a catalyst such as concentrated sulfuric acid. This reaction requires controlling conditions such as temperature and the proportion of reactants, heating and refluxing for a certain period of time, so that the two can fully react to generate 3-fluorobenzene-1,2-dicarboxylic acid esters.
Second, 3-fluorobenzoic acid can also be used as a starting material. First, it is prepared into a corresponding acid chloride, and chlorination reagents such as thionyl chloride can be used to react with it. After forming an acid chloride, it reacts with an o-hydroxybenzoate compound. This reaction needs to be carried out under appropriate alkaline conditions, such as the environment of organic bases such as pyridine, in order to promote the smooth occurrence of the reaction, and then generate the target product 3-fluorobenzene-1,2-dicarboxylate.
During the preparation process, each step of the reaction needs to precisely control the reaction conditions. Due to factors such as temperature, pH, ratio of reactants and reaction time, the yield and product purity of the reaction are greatly affected. And after each step of the reaction, it is often necessary to use separation and purification methods such as extraction, distillation, and recrystallization to obtain high-purity products, so as to meet the needs of subsequent experiments or industrial applications.
What is the price range of 3-Fluorobenzene-1,2-Dicarboxylate in the market?
I don't have the exact number of "3 - Fluorobenzene - 1,2 - Dicarboxylate" in the market price range. This is because the price of the compound often varies with many factors.
First, purity is the key factor. If the purity is extremely high and almost perfect, it can be used in high-end scientific research experiments, and its price will be high; on the contrary, if the purity is slightly lower, it is suitable for scenarios with slightly slower requirements, and the price may be slightly reduced.
Second, the situation of supply and demand determines the price. If the market demand for it is strong and the supply is limited, if a large demand for it emerges in a scientific research field, the output will not be sufficient, and the price will rise; if the supply exceeds the demand, the price may decline.
Third, the difficulty of preparation also affects the price. If the preparation requires complex processes, rare raw materials, and harsh conditions, the cost must be high, resulting in a high price; if the preparation is relatively simple, the cost is controllable, and the price may be close to the people.
Fourth, the purchase quantity varies. For bulk purchases, merchants may give preferential prices due to economies of scale; for small purchases, the unit price may be high.
Because the specific purity, market supply and demand, preparation details, and purchase quantity of this compound are not known, it is difficult to determine its market price range. If you want to know the details, you can consult chemical product suppliers, reagent sales platforms, or refer to relevant industry reports to get a more accurate price.