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What are the main uses of 3-fluoro- (trans-4-propylcyclohexyl) benzene?
3-Xan- (trans-4-methylcyclohexyl) benzyl is commonly found in the field of medicinal chemistry, and its main uses are quite extensive.
In drug synthesis, this compound can be used as a key intermediate. Due to its specific chemical structure, it can participate in many reactions and help build drug molecular structures with specific physiological activities. For example, in the development of some cardiovascular disease treatment drugs, it can precisely connect other functional groups with its unique spatial structure and electronic properties, thereby optimizing the binding ability of the drug to the target, and improving the efficacy and selectivity of the drug.
In the field of organic synthetic chemistry, 3-tantal- (trans-4-methylcyclohexyl) benzyl is also an important raw material. Organic chemists can modify and derive its structure through various reactions, such as substitution reactions, addition reactions, etc., to synthesize more complex and diverse organic compounds, providing a basis for the research and development of organic materials and fine chemicals.
At the same time, it also plays an important role in biological activity research. Researchers can introduce it into biological activity testing systems to explore its mechanism of action on specific enzymes, receptors and other targets in organisms, providing key clues for the discovery and development of new drugs.
What are the physical properties of 3-fluoro- (trans-4-propylcyclohexyl) benzene?
3-Alkan- (trans-4-methylcyclohexyl) benzene. The physical properties of this substance are as follows:
It is an organic compound. It is mostly liquid at room temperature and pressure, but it also changes due to specific environmental conditions. Looking at its appearance, it may be a colorless to light yellow transparent liquid with certain fluidity.
The density of this substance is slightly smaller than that of water, about 0.85-0.95 g/cm ³, so it will float on the water surface when placed in water. Its boiling point is in a certain temperature range, roughly between 250-300 ° C, due to intermolecular forces and structural characteristics. The characteristics of the boiling point make it have specific applications in chemical operations such as separation and purification.
In terms of melting point, it is about -10-10 ° C, indicating that it is easier to change from liquid to solid at lower temperatures.
In terms of solubility, 3-alkan- (trans-4-methylcyclohexyl) benzene is insoluble in water. Because water is a polar molecule, and the polarity of the organic molecule is weak, according to the principle of "similarity and compatibility", the two are incompatible. However, it is soluble in a variety of organic solvents, such as toluene, dichloromethane, ether, etc. In organic synthesis reactions, such organic solvents are often used as reaction media to facilitate the reaction.
In addition, the refractive index of the compound is also a specific value, between about 1.50 and 1.55. The determination of refractive index can be used to identify the substance or determine its purity. Its vapor pressure is relatively low at room temperature and the volatility is weak. However, at higher temperatures, the vapor pressure increases and the volatility is enhanced. Safety measures such as ventilation should be paid attention to during operation.
Is 3-fluoro- (trans-4-propylcyclohexyl) benzene chemically stable?
The stability of the chemical properties of 3-meta- (trans-4-methylcyclohexyl) benzene depends on many factors. The structure of this compound, which contains benzene ring and trans-4-methylcyclohexyl group, interacts with each other, which has a great influence on its stability.
The benzene ring has a conjugated system, which makes the electron cloud of the benzene ring uniformly distributed and endows it with high stability. In 3-meta- (trans-4-methylcyclohexyl) benzene, the conjugation of the benzene ring still exists, but it is connected to trans-4-methylcyclohexyl, and its electron cloud distribution may change.
The existence of trans-4-methylcyclohexyl is due to the spatial arrangement of methyl and cyclohexyl, or the steric hindrance effect occurs within the molecule. If this hindrance is appropriate, the molecular conformation can be relatively stable; if it is too large, the molecular stability may be damaged.
Furthermore, the environment in which 3-diver- (trans-4-methylcyclohexyl) benzene is located, such as temperature, pH, light, etc., also affects its stability. Under high temperature, the thermal motion of the molecule intensifies, or the vibration of the chemical bond intensifies, resulting in a decrease in stability. In the environment of strong acid and alkali, it may react with acid and alkali, which affects the stability. If light provides energy and reaches the threshold of molecular chemical bond breaking energy, it will also cause its structure to change and reduce its stability.
In summary, the chemical stability of 3-diver- (trans-4-methylcyclohexyl) benzene is not determined by a single factor, but is the result of the interaction of molecular structure and external environment. Its stability requires comprehensive consideration of structural characteristics and external conditions to make an accurate conclusion.
What is the production process of 3-fluoro- (trans-4-propylcyclohexyl) benzene?
The production process of 3-bromo- (trans-4-methylcyclohexyl) benzene is really delicate and elegant.
Its starting materials are often selected from suitable aromatics and halogenated cyclohexane derivatives. First, in a specific reactor, aromatics and halogenated cyclohexane derivatives are mixed in a precise ratio, which depends on the activity of the reactants and the purity of the target product.
Then, an appropriate amount of catalyst is added. This catalyst is mostly metal salts or organometallic complexes, which play a key catalytic role in the reaction and can significantly reduce the activation energy of the reaction and accelerate the reaction process. At the same time, in order to make the reaction proceed smoothly and efficiently, specific additives need to be added. The role of additives is to stabilize the reaction system and regulate the activity of the reactants.
The reaction environment is also extremely important. The temperature must be strictly controlled in a certain range, such as between [X] ° C and [X] ° C. If the temperature is too high or too low, the reaction rate may be abnormal and side reactions may increase. The pressure also needs to be maintained at an appropriate value to ensure the phase state of the reactants and the kinetic balance of the reaction.
During the reaction process, the speed and method of stirring cannot be ignored. Moderate and uniform stirring can promote the full contact of the reactants and improve the uniformity and efficiency of the reaction.
After the reaction is completed, the product needs to go through multiple fine separation and purification steps. First, the extraction method is used to initially separate the product by taking advantage of the difference in solubility between the product and the impurities in different solvents. Then the distillation method is used to further purify the product according to the different boiling points. Or it is supplemented by recrystallization to remove trace impurities to achieve extremely high purity standards.
After this series of rigorous and complicated steps, high-purity 3-bromo- (trans-4-methylcyclohexyl) benzene can be prepared, which meets the strict requirements of its quality in many fields.
What is the price range of 3-fluoro- (trans-4-propylcyclohexyl) benzene in the market?
3-Bromo- (trans-4-methylcyclohexyl) benzene is in the market, and its price range is difficult to determine. The price varies with many factors, such as the abundance of the material, the difficulty of preparation, and the amount of market demand.
If the material is easy to produce, the preparation method is simple and common, and the market demand is not Yin Sheng, then its price is low. On the contrary, the material is rare, and the preparation requires complex methods, heavy investment and fine skills. If the market seeks and cuts, the price will be high.
However, according to common sense, if such an organic compound is of ordinary quality and not extremely pure, the price per gram in the market of chemical raw materials may be between tens and hundreds of dollars. If its purity is excellent and reaches the high standard required for scientific research, the price should be doubled, or to thousands of gold per gram.
The market is volatile and the price is uncertain. This is only an approximate guess. To know the exact price, you must ask the merchants of chemical materials, or check the recent transaction price on the relevant trading platform to obtain a more accurate amount.