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3-Fluoro-Benzeneaceticaci

3-Fluoro-Benzeneaceticaci

Hongda Chemical

Specifications

HS Code

985261

Chemical Formula C8H7FO2
Molar Mass 154.14 g/mol
Appearance Solid
Melting Point 75 - 77 °C
Boiling Point 261.6 °C at 760 mmHg
Density 1.314 g/cm³
Solubility In Water Slightly soluble
Pka 3.98
Flash Point 112.1 °C
Refractive Index 1.509

As an accredited 3-Fluoro-Benzeneaceticaci factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of 3 - fluoro - benzeneacetic acid packaged in a sealed, corrosion - resistant container.
Storage 3 - Fluoro - benzeneacetic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent moisture absorption and evaporation. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. This storage method helps maintain its stability and safety.
Shipping 3 - fluoro - benzeneacetic acid is shipped in accordance with strict chemical regulations. It is carefully packaged in corrosion - resistant containers. Shipment is via approved carriers, ensuring proper handling to prevent spills and maintain safety during transit.
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3-Fluoro-Benzeneaceticaci 3-Fluoro-Benzeneaceticaci
General Information
Historical Development
3-Fluorophenylacetic acid is also an organic compound. At the beginning, chemists studied the properties of substances and hoped to expand the field of chemistry. In the past, when organic synthesis was just beginning, scholars worked hard to explore the production of new substances.
At that time, all kinds of synthetic methods were not perfect, but fearless people tried new ways with perseverance. After years of research, the method of making 3-fluorophenylacetic acid was obtained. At the beginning, the yield was not high, and the quality was not up to par.
However, chemists worked tirelessly and moved forward. With the advance of science and technology, the instruments became more refined, and the theory became clearer. The method of synthesis is increasingly exquisite, the yield is gradually increasing, and the quality is also excellent. Therefore, 3-fluorophenylacetic acid is gradually used in the fields of medicine and materials, contributing to the progress of chemistry, becoming the fruits of past exploration, and also initiating a new course of future research.
Product Overview
3 - Fluoro - Benzeneacetic acid (3 - fluorophenylacetic acid) is also an organic compound. Its shape may be white to off-white crystalline powder with a specific chemical structure. On the benzene ring, fluorine atoms are cleverly connected to acetic acid groups, giving it unique chemical properties.
In the field of organic synthesis, this compound has a wide range of uses. It can be used as a key intermediate and participate in the construction of many complex organic molecules. Due to the introduction of fluorine atoms, it can significantly change the physical and chemical properties of compounds, such as enhancing their lipophilicity and affecting reactivity.
And it has also attracted much attention in the field of medicinal chemistry, and may provide important raw materials for the development of new drugs, helping to create drugs with unique therapeutic effects. 3-Fluoro-Benzeneacetic acid can be converted into a variety of bioactive derivatives through exquisite reaction design and synthesis process, opening up new avenues for medical exploration.
Physical & Chemical Properties
3 - Fluoro - Benzeneacetic acid is an organic compound. Its physical properties are mostly white crystalline solids at room temperature, with a more delicate texture and a slightly special odor. The melting point is within a certain range, according to accurate determination, it is about XX ° C. This characteristic makes it undergo phase transition under a specific temperature environment.
Chemical properties, the carboxyl group in this substance is acidic and can neutralize with bases to form corresponding carboxylates and water. And due to the presence of benzene ring and fluorine atoms, the electron cloud density on the benzene ring changes, which affects the activity and location of electrophilic substitution reactions. Fluorine atoms have large electronegativity, the electron cloud density of the ortho-para-site of the benzene ring is relatively reduced, and the meta-site is relatively high. The electrophilic substitution reaction is more likely to occur in the meta-site, and is widely used in the field of organic synthesis.
Technical Specifications & Labeling
Nowadays, there is a technique for making 3 - Fluoro - Benzeneacetic acid, and the method should follow the technical specifications and labels (commodity parameters). Prepare all materials first, and prepare them according to the party, so that the quality and quantity of the goods match the number. When operating, you must follow the rules, abide by the rules of caution, and do not make mistakes. After the finished product, check its logo in detail, check its parameters, color, taste and shape, all of which are in line with the specified standards. Observe its purity, measure its composition, and ensure that it is accurate. Those who meet this technical specification and label (commodity parameters) can be used for good products. This is the preparation of 3 - Fluoro - Benzeneacetic acid, in the technical specifications and labeling (commodity parameters) should also be noted.
Preparation Method
To make 3-Fluoro-Benzeneacetic acid, first take fluorobenzene and acetonitrile as raw materials. Make fluorobenzene and acetonitrile in a specific container and initiate a reaction at a suitable temperature.
At the beginning, fluorobenzene and acetonitrile are replaced by a method to produce an intermediate product. In this step, precise temperature control is required to observe the reaction process. When the reaction is complete, the intermediate product is obtained.
times, the obtained intermediate product is hydrolyzed. During hydrolysis, adjust its pH, temperature and reaction time. Under suitable conditions, the intermediate product is converted into 3-Fluoro-Benzeneacetic acid.
During this process, there is a monitoring mechanism. At each step of the reaction, the purity and composition are measured by instruments. If there is any deviation, the reaction parameters are adjusted. In this way, 3-Fluoro-Benzeneacetic acid is prepared through raw material selection, reaction steps and monitoring.
Chemical Reactions & Modifications
In recent years, 3 - Fluoro - Benzeneacetic acid has been modified by anti-modification, which has many benefits. The reverse is also the same, and the method is used to improve it. At the beginning, the usual method is used to improve it, but the effect is not yet effective, the rate is mediocre, and it is not good.
Thinking about it, or the method is not good. So it is new, and the reverse part of it is improved, and the force is easy to catalyze. Repeated, get a method that can increase the rate and the amount of the catalyst. This new way is also to study it in the context of the reverse and the catalytic material, so that the reverse is good.
And think about the way of modification, so that the method can improve the quality of its molecules. Introduce new radicals into it, and hope for its properties. At the beginning, the properties are not as expected. After studying the theory, the method of introducing it has been introduced, and the results are satisfactory. Today, the anti-modification of 3-Fluoro-Benzeneacetic acid has obtained a little, and I hope it will be better in the future.
Synonyms & Product Names
3 - Fluoro - Benzeneacetic acid, which is also in the field of chemical research, its synonymous name and the name of the commodity, are the ones that our generation should investigate. It covers more than one thing, and there is a risk of confusion between communication and records.
Fu 3 - Fluoro - Benzeneacetic acid, or it is called "3 - fluorophenylacetic acid", which is the common name obtained according to its chemical structure. As for the trade name, the industry may have another title due to marketing and characteristics. However, no matter what the name is, it refers to this specific compound.
We chemical researchers must clarify their synonyms and trade names, so that the research process can be smooth and smooth, and the records are detailed and correct. In this way, we can move forward steadily on the path of chemistry, explore the secrets, and gain a glimpse of the mystery of the chemical world.
Safety & Operational Standards
3-Fluoro-Benzeneacetic acid (3-fluorophenylacetic acid) is an important chemical in chemical research. Safety and operating practices are essential during its experimental preparation and use.
The first word is safe, this chemical may have certain chemical activity and potential danger. Experimenters must wear appropriate protective equipment, such as lab clothes, gloves and goggles. If the skin is inadvertently exposed, it may cause irritation, or even absorb adverse effects in the body; eye contact, especially harmful, or cause eye damage. Operate in a well-ventilated environment, if inhaled its volatile aerosol or dust, it may damage the respiratory system.
At the level of operation specifications, when using 3 - Fluoro - Benzeneacetic acid, use clean and accurate utensils. Weighing should be rigorous to ensure accurate dosage, errors or deviations in experimental results. During the dissolution or reaction process, reagents should be added in a specific order, and attention should be paid to reaction conditions, such as temperature, pH, etc. When heating, the temperature should be controlled smoothly, and the reaction should be out of control. After the experiment is completed, properly dispose of the remaining chemicals, do not dump them at will, collect them according to regulations, and dispose of them by professional channels to avoid polluting the environment.
Storage should also be cautious, in a cool, dry and ventilated place, away from fire sources and oxidants, etc. Labels are clearly marked with information such as names, characteristics and hazard warnings for easy access and management. Only by strictly following safety and operation regulations can we ensure the smooth development of 3-Fluoro-Benzeneacetic acid related experiments, and ensure the safety of experimenters and environmental safety.
Application Area
Today, there is a chemical substance 3 - Fluoro - Benzeneacetic acid, which has a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs to cure various diseases. In the field of materials science, it can be integrated into polymer materials through specific reactions to improve material properties, such as enhancing their stability and functionality. In fine chemistry, it can be used to prepare special fragrances and additives to increase the uniqueness of its products. Its application potential is huge. If it can be well studied and used rationally, it will shine brightly in many fields and bring many conveniences and innovations to our lives.
Research & Development
We have been dedicated to the research of 3-Fluoro-Benzeneacetic acid for a long time. This compound has unique properties and contains endless mysteries. We studied its chemical structure, analyzed its reaction mechanism, and repeatedly explored it in various experiments.
At the beginning, the synthesis process was full of thorns, and many attempts were frustrated. However, we were not discouraged. After repeatedly debugging the reaction conditions and improving the synthesis steps, we finally achieved something. The purity and yield of the prepared product gradually became ideal.
At the same time, its application potential in the field of organic synthesis was explored. After a series of experiments, it was found that it can be used as a key intermediate in specific reactions, opening up a new path for the creation of new compounds.
In the future, we will continue to conduct in-depth research, expand its application scope, and strive to make even more outstanding progress in this field, contributing to the development of chemistry.
Toxicity Research
The detailed review of the material properties is related to the safety of people's livelihood. Today there is 3 - Fluoro - Benzeneacetic acid, and the investigation of its toxicity cannot be ignored.
When studying toxicity, first look at its shape. The shape of this substance, under various conditions, may change in color. And when it touches other things, it also produces different responses. This is the basis for toxicity investigation.
Then observe the effect of its entry into the body. Either through the mouth and nose, or seeping into the skin, after entering the body, there are traces of the internal organs and meridians involved. Observe whether it disturbs the smooth flow of qi and blood, and disrupts the functions of the internal organs.
It also examines its impact on the environment. Scattered between water and soil, whether it is harmful to all living things. Flowers, plants, insects and fish are all under consideration.
The investigation of toxicity is really an important task. It is related to the health of everyone and the harmony of heaven and earth. Only by exploring in detail can we obtain its true meaning, so as to maintain the safety of the people and the peace of the environment.
Future Prospects
In today's world, science and technology are advancing day by day, and the field of chemistry is no exception. I am focusing on the research of 3-Fluoro-Benzeneacetic acid, and I often think about its future development.
Looking at the present, this compound has emerged in the field of pharmaceutical research and development. Many experiments have shown that its unique structure may bring new opportunities for the creation of new drugs, the treatment of difficult diseases, and new opportunities. In time, it can help doctors and solve the suffering of patients.
In the field of material science, it also has hidden capabilities. Or it can optimize material properties, making materials more tough and durable, and contribute to the construction, manufacturing and other industries.
I am convinced that if everyone works together and makes unremitting exploration, 3-Fluoro-Benzeneacetic acid will be able to shine in the future, for the well-being of mankind, open up a broad environment, and realize the ambition of our researchers, living up to the trust of the times.
Where to Buy 3-Fluoro-Benzeneaceticaci in China?
As a trusted 3-Fluoro-Benzeneaceticaci manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluoro-Benzeneaceticaci supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-fluorophenylacetic acid?
3-Tyrosine acid, also known as L-DOPA, is the key to the treatment of Parkinson's disease. In Parkinson's disease, dopamine can cause death, resulting in less dopamine production, resulting in diseases such as shock, tremor, and myorectosis. 3-Tyrosine acid acts as a dopamine precursor, which can penetrate the blood barrier, reduce dopamine and dopamine deficiency by dopamine carboxylase, and improve the symptoms of Parkinson's disease.
It can effectively improve the ability of patients to perform well, and can greatly improve the life expectancy of patients. However, it is also not effective, and it is easy to have many side effects when used in large quantities during the period. Often, it is caused by the reaction of the digestive tract, such as heart attack and vomiting, due to the stimulation of peripheral dopamine. There are also side effects, such as depression, which is caused by involuntary stimulation of dopamine during the period, resulting in mental change. There are also many psychiatric disorders, such as hallucinations, delusions, depression, etc., or due to the wide effect of dopamine on the body, which affects many spiritual pathways.
Therefore, the use of 3-tyrosine in the bed requires a balance of advantages and disadvantages. According to the patient's condition, age, and tolerance, a plan of use is carefully formulated to maximize the effectiveness and minimize side effects, so as to maximize the benefit of the patient.
What are the physical properties of 3-fluorophenylacetic acid?
3-Hydroxybutyric acid is an endogenous substance in the human body that exists in normal physiological processes and has specific physical properties. It is described as follows:
Its appearance is usually colorless to light yellow liquid, which is viscous. Looking at its color, pure is clear and transparent, and there are no impurities or precipitation. This property is similar to many other liquid organic compounds, and can be clearly distinguished by the naked eye under normal light conditions.
When it comes to smell, 3-hydroxybutyric acid has a slightly weak and special smell, but it is not pungent or unpleasant. This smell is similar to that of general fatty acids and their derivatives, but its smell is very light, and it is difficult for ordinary people to detect if they do not deliberately get close and smell it.
3-hydroxybutyric acid is soluble in water due to the presence of a hydroxyl group (-OH) in the molecular structure, which can form hydrogen bonds with water molecules, thus enhancing its solubility in water. Not only that, it also has a certain solubility in some organic solvents such as ethanol and acetone. This property is derived from the principle of similarity compatibility. Because the molecule has both polar and non-polar parts, it can interact with a variety of organic solvents.
As for the boiling point, due to the presence of hydrogen bonds and other forces between molecules, its boiling point is relatively high. Specifically, at standard atmospheric pressure, it is about a certain temperature range. A higher boiling point means that more energy needs to be supplied to make it change from liquid to gaseous state. This property is of great significance when separating and purifying it. It can be separated from other substances with a large difference in boiling point by controlling the temperature.
In terms of melting point, 3-hydroxybutyric acid also has a specific value. When it is below the melting point temperature, it will condense from liquid to solid. The transition of this physical state is also influenced by intermolecular forces. The existence of the melting point makes it necessary to pay attention to the effects of its solid state properties such as loss of fluidity during storage and transportation if the ambient temperature is below the melting point.
Is 3-Fluorophenylacetic Acid Chemically Stable?
3-Hydroxybutyric acid, its chemical properties are relatively stable.
This substance can generally maintain a stable state under normal temperature and pressure, as long as it does not come into contact with highly active chemical substances such as strong oxidants, strong acids, and strong bases. In its molecular structure, although the presence of hydroxyl and carboxyl groups gives it a certain reactivity, it is not easy to spontaneously produce significant chemical changes in the conventional environment.
However, if it is placed in a high temperature environment, the chemical bond vibration in the 3-hydroxybutyric acid molecule intensifies and the energy increases, which may trigger a dehydration reaction. The hydroxyl group in the molecule interacts with the carboxyl group, loses a molecule of water, and forms a lactone structure. If there is a suitable catalyst in the environment, it will also accelerate the process of such reactions.
If it encounters a specific alcohol, under the action of an acidic catalyst, the carboxyl group of 3-hydroxybutyric acid will be esterified with the hydroxyl group of the alcohol to form a corresponding ester compound. However, without a catalyst and suitable reaction conditions, this esterification reaction is difficult to occur naturally.
Looking at its situation in aqueous solution, 3-hydroxybutyric acid will ionize a small amount due to the weak acidity of the carboxyl group, generating hydrogen ions and corresponding acid ions, but the degree of ionization is extremely limited, and the solution as a whole can still maintain a relatively stable state.
In conclusion, under common and mild environmental conditions, the chemical properties of 3-hydroxybutyric acid are quite stable, but once the conditions change, contact with specific reactants, at special temperatures, or with catalyst intervention, the corresponding chemical reaction may occur.
What are the preparation methods of 3-fluorophenylacetic acid?
To prepare ethyl tri-hydroxybutyrate, the methods are as follows:
First, the esterification reaction is carried out under heating conditions with hydroxybutyric acid and ethanol as materials, and concentrated sulfuric acid as catalyst. The text says: "Ethyl tri-hydroxybutyrate can be obtained by using hydroxybutyric acid and ethanol as raw materials, concentrated sulfuric acid as catalyst, and heating to esterify it." In this reaction, concentrated sulfuric acid has catalytic power and can promote the reaction to generate esters. However, it should be noted that after the reaction is completed, due to the corrosive nature of sulfuric acid, it needs to be properly handled, and this reaction is reversible. To increase the yield, the amount of a reactant can be increased, or the product can be removed in time.
Second, hydroxybutyric acid can be formed into acyl chloride first, and then reacted with ethanol. That is, hydroxybutyric acid interacts with thionyl chloride and other reagents to obtain hydroxybutyryl chloride, which then meets ethanol. The acid chloride has high activity and is easy to react with ethanol to form esters. As the ancient saying: "Shilling hydroxybutyric acid and thionyl chloride to obtain hydroxybutyryl chloride, and then interacting with ethanol, ethyl tri-hydroxybutyrate can be obtained." This approach can avoid the reversible drawbacks of esterification reaction and improve the yield. However, thionyl chloride is toxic and corrosive, and it must be operated in a well-ventilated place, and the equipment requirements are also high.
Third, the transesterification reaction can be used. Methyl hydroxybutyrate and ethanol are used as the starting materials, and ethyl tri-hydroxybutyrate is obtained by transesterification under the action of Take methyl hydroxybutyrate and ethanol, add a catalyst, and perform a transesterification reaction to obtain the target ester. "The conditions of this method may be milder, but the choice of catalyst and the regulation of reaction conditions are crucial to achieve optimal yield and purity.
What is the price range of 3-fluorophenylacetic acid in the market?
Looking at the current market, the price of 3-hydroxybutyric acid fluctuates quite a lot due to many reasons. It may be used in various fields such as medicine and chemical industry, with different needs and different prices.
In the process of refining medicine, the purity of 3-hydroxybutyric acid required is extremely high, and the preparation is difficult, so its price is high. In the market, the price per gram of such high purity may reach tens of gold or even hundreds of gold. The reason is that medicine is related to human life, and the purity and impurities are strictly controlled. The preparation process is complicated, and it consumes huge manpower, material resources, and financial resources.
If used in chemical synthesis, the requirements are slightly lower, and the price is also reduced. Usually purchased in bulk, per kilogram or between hundreds of gold and thousands of gold. Chemical applications are wide and the dosage is large, but the purity requirements are not as severe as those of medicine, and the preparation cost is slightly lower, which is a reduction in price.
There are different sources, natural extractors, complicated processes, difficult to find raw materials, and high prices. For chemical synthesizers, although they can be mass-produced, the cost of upfront R & D investment and equipment purchase should not be underestimated, so their price is not low. And changes in market supply and demand also affect their price. If demand is strong and supply is small, the price will rise; if supply is sufficient and demand is weak, the price will fall.
In summary, the price of 3-hydroxybutyric acid in the market, high-purity pharmaceutical use, tens of gold to more than 100 gold per gram; chemical use, hundreds of gold to thousands of gold per kilogram spectrum, due to the use, purity, source, supply and demand and other factors intertwined, causing its price fluctuations.