3-Hydroxy-5-methoxybenzoic acid, which is quite useful in the fields of medicine and chemical industry.
In the field of medicine, it can be a key raw material for the synthesis of many drugs. The properties of hydroxyl and methoxy groups in the structure make it have specific physiological activities and pharmacological effects. For example, in the creation of some cardiovascular disease drugs, it can participate in the reaction, shape the key structure of the drug, help the drug to accurately bind to the target, or regulate the physiological and biochemical processes in the body, so as to achieve the purpose of treating cardiovascular diseases. In the development of anti-inflammatory drugs, it can also play a role, or it can affect inflammation-related signaling pathways, so as to achieve anti-inflammatory effect.
In the chemical industry, it can be used as an intermediary in organic synthesis. With its unique chemical structure, it can participate in various organic reactions, laying the foundation for the preparation of a variety of high-value-added fine chemicals. For example, in dye synthesis, it can be introduced into the molecular structure of the dye through specific reaction steps to give the dye special color and properties, such as improved light resistance and washable properties. In the field of fragrance synthesis, it may become a key component in the construction of a unique aroma structure, and it can be reacted with other compounds to create a unique fragrance. In the field of polymer materials, it may be added to the polymer as a modifier, and its reactive group interacts with the polymer chain to improve the physical and chemical properties of the material, such as enhancing the mechanical strength of the material and improving the thermal stability.

3-Hydroxy-5-methoxyadipic acid, its physical properties are as follows.
This substance is at room temperature, or in the shape of a solid state. Looking at its appearance, it is often in the form of a white powder, delicate and uniform, like fresh snow in winter, pure and free of variegation. If you touch it lightly, it seems to have the feeling of fine particles, but it is also smooth.
In terms of its smell, it is almost odorless, close to a fine smell, and it is difficult to detect a special smell. It is like being in a quiet and undisturbed environment, without pungent or rich smell to disrupt people's sense of smell.
As for solubility, it has a certain solubility in water. When placed in water, the powder can be seen to disperse slowly in the water at first, like a star scattered, and then gradually dissolve to form a clear or slightly cloudy solution, depending on its concentration. In organic solvents, there is also a specific solubility, but different organic solvents have different degrees of solubility.
Its melting point and boiling point are also important physical properties. The value of the melting point, according to accurate measurement, is within a certain temperature range. When the temperature gradually rises to the melting point, the substance begins to melt from a solid state to a liquid state like ice and snow in the warm sun, and the process is smooth and orderly. The number of boiling points is also determined under the corresponding conditions. At this temperature, the liquid will boil violently and be converted into a gaseous state to dissipate.
In terms of density, it has a certain value after rigorous measurement, reflecting its mass characteristics per unit volume. This value is higher or lower than other similar substances, which is one of its unique physical signs.
In summary, 3-hydroxy- 5-methoxyadipic acid has various physical properties, and each property is related to each other, which together constitute the physical properties of this substance. It is of great significance in chemical research and related application fields.

The chemical synthesis of 3-hydroxyl-5-methoxybenzoic acid has various paths.
First, the corresponding phenols can be started. First, the phenolic hydroxyl group is properly protected to prevent it from reacting unprovoked in the subsequent reaction. Then, through the halogenation reaction, a halogen atom is introduced at a suitable position in the benzene ring. The commonly used halogenating agent includes halogen elemental or halogenated reagents. This halogen atom can lay the foundation for the subsequent nucleophilic substitution reaction. Then, the methoxy group is introduced into the benzene ring by the nucleophilic substitution reaction with a reagent containing methoxy group. Next, after a specific oxidation step, the methyl group is converted into a carboxylic group, and a strong oxidant such as potassium permanganate is commonly used. After a series of precise operations, the target product can be obtained
Second, the benzoic acid derivative is used as the starting material. If the benzoic acid derivative has a modifiable group at a suitable position, the methoxy group can be introduced by a specific reaction. For example, by the Williamson ether synthesis method, the methoxy group is introduced by the reaction of alkoxides with halogenated hydrocarbons. Then, at another suitable position, the hydroxyl group is introduced by a suitable reaction. Hydroxyl groups can be introduced in the appropriate position by the aromatic ring electrophilic substitution reaction, under the electrophilic substitution conditions commonly used in phenolic compounds. After such a series of reactions, 3-hydroxy- 5-methoxybenzoic acid can also be synthesized.
Third, some more complex organic synthesis strategies can be adopted, such as the coupling reaction using metal catalysis. The carbon-carbon bond is formed by coupling reaction between a halide containing benzene ring and an organometallic reagent containing methoxy and carboxyl precursors under the action of a suitable metal catalyst such as palladium catalyst. Subsequent to the conversion of necessary functional groups, such as oxidation, hydrolysis and other reactions, the groups are precisely modified to finally obtain the target 3-hydroxy- 5-methoxybenzoic acid. These methods need to be carefully selected and optimized according to the actual situation, considering the availability of raw materials, the difficulty of reaction conditions, the yield and the number of side reactions, etc., in order to effectively synthesize the target compound.

3-Hydroxy-5-methoxybenzoic acid should be carefully paid attention to the following points when storing and transporting:
First, it concerns storage. This substance is quite sensitive to environmental conditions and should be placed in a cool, dry and well-ventilated place. Avoid open fires and hot topics to prevent fires or cause their properties to change. Because it has certain chemical activity, it should be stored separately and at a safe distance from the above-mentioned chemicals in contact with oxidants, acids, alkalis and other substances, or react violently. The storage area should be equipped with suitable containment materials for possible leakage.
Second, it involves transportation. Before transportation, it is necessary to ensure that the packaging is complete and well sealed to prevent leakage due to package damage caused by vibration and collision during transportation. Appropriate transportation tools should be selected during transportation and implemented in accordance with relevant regulations on the transportation of hazardous chemicals. When handling, operators need to wear appropriate protective equipment, such as protective gloves, protective clothing and protective glasses, to avoid skin contact and eye splashing. If a leak is accidentally made, the contaminated area should be quickly isolated and personnel should be restricted from entering and leaving. Emergency responders need to wear gas masks and protective clothing. Do not let the leak come into contact with combustible substances. If a small amount leaks, it can be absorbed by inert materials such as sand and vermiculite. If a large amount leaks, it is necessary to build an embankment or dig a pit for containment, and report it to the relevant departments in time to clean up and dispose of it according to professional

Today there is 3-hydroxy- 5-methoxybenzoic acid, what is the price of its market? The price of this drug is related to various factors, and it is difficult to cover it in one word.
First, it is related to the method of refining. If it is processed by the ancient method, it requires a lot of labor and requires good materials, and its price will be high; if it is made by new techniques, it can save labor and time, and the cost may be reduced, and the price will also become easier.
Second, it depends on the price of the raw materials. If the raw materials of this medicine are easy to obtain and the price is cheap, the price of the medicine may not be high; if the raw materials are rare and difficult to obtain, the price will be expensive.
Third, the trend of market supply and demand is also the key. If doctors use more and patients compete for more, but there are few products, the supply is in short supply, and the price will rise; if there are few people in need, the supply will exceed the demand, and the price will naturally decrease.
Fourth, the distance of the place of origin also has an impact. If the place of origin is near the city, the freight will be reduced, and the price may be slightly flat; if it is far away elsewhere, the freight will be large, and the price will also be increased.
In today's world, prices vary from place to place, and it is difficult to determine the price. If you want to know the detailed price, you can consult the merchants of the pharmaceutical company to get the true price.