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3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid

3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    121165

    Chemical Formula C10H14BO4F
    Molecular Weight 228.025
    Appearance Solid
    Color White to off - white
    Melting Point 96 - 100 °C
    Boiling Point Estimated high value due to decomposition
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Around 8 - 9 (boronic acid group)
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

    As an accredited 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3 - fluoro - 5 - (isobutoxy)benzeneboronic Acid in sealed chemical - grade packaging.
    Storage Store 3 - fluoro - 5 - (isobutoxy)benzeneboronic acid in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption, which could degrade the compound. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid chemical reactions.
    Shipping 3 - fluoro - 5 - (isobutoxy)benzeneboronic acid is shipped with strict adherence to chemical transport regulations. Packed securely in appropriate containers, it's dispatched via carriers experienced in handling such chemicals, ensuring safe transit.
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    3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid
    General Information
    Historical Development
    I have tasted the industry of chemical industry, and it is changing with each passing day. All kinds of products depend on the intensive research of craftsmen. Today there is a thing called 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid. It first appeared in the world, and it was not important for humans. At that time, the techniques were not refined, and it was as difficult to obtain this thing as going to the sky.
    However, the wise men did not give up, and they worked hard to think about it, and they went through the cold and summer for many years. Looking at the classics and trying new methods, in the midst of various difficulties, they found an opportunity to break through. At the beginning, the output was very small, and the quality was not pure. Everyone made persistent efforts to improve the process, adjust the heat, and match the dosage.
    The years pass, and the skills are becoming more and more mature. The output of this product is gradually increasing Since its advent, it has been widely used in the fields of medicine and materials. The difficulties of the past have finally transformed today's achievements, and it has also left valuable lessons for future generations to explore the way of chemical industry, making it more stable and faster in the road of science and technology.
    Product Overview
    Today there is a product called "3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid". This is a product of fine chemicals, which is quite useful in the field of organic synthesis. Its properties are stable, and its appearance is often white crystalline.
    The preparation of this product requires multiple complicated processes, temperature control, time control, and precise operation. It can be used as a key intermediate in pharmaceutical research and development to help with medicinal properties; in materials science, it can also add its characteristics and enhance the superiority of materials.
    Looking at its structure, fluorine atoms, isobutoxy groups and phenylboronic acid groups are cleverly connected, giving it unique chemical activity. Due to its unique structure, the reaction activity is controllable, and it can be compatible with many reagents to achieve diverse chemical transformations. It is a good material for chemical research and development, with broad prospects and unlimited potential.
    Physical & Chemical Properties
    3-Fluoro-5- (isobutoxy) phenylboronic acid, the physical and chemical properties of this compound are important to our research. Its appearance may be white to off-white powder, which is a physical property visible to the naked eye. In terms of solubility, it may exhibit moderate solubility in specific organic solvents, but the solubility in water may need to be investigated in detail.
    Its melting point is a key physical parameter. After accurate determination, the temperature node of its phase transition can be defined, providing a basis for practical application and storage. In terms of chemical activity, the structure of phenylboronic acid endows it with unique reactive properties, or it can participate in a variety of organic synthesis reactions, such as specific reactions with compounds containing hydroxyl groups, amino groups and other functional groups, laying the foundation for the construction of novel organic structures. Its stability cannot be ignored. Under different environmental conditions, it is necessary to consider whether it will undergo chemical changes such as decomposition and metamorphism, so that this compound can be better used in various chemical research and practice.
    Technical Specifications & Labeling
    There is a product today, named 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid. To clarify its technical specifications and identification (product parameters), it is necessary to study it carefully.
    The preparation of this product requires a rigorous method. The selection of materials must be in line with its quality. When reacting, temperature, pressure and other conditions must be precisely controlled. For example, in the reactor, the temperature should be stable in a certain area to make the reaction smooth and obtain high-quality products.
    In terms of its identification, the key parameters should be listed in detail. Such as purity geometry, impurity content, which is related to the quality of the product. On the packaging, it is also necessary to clarify the product name, specifications, etc., so that the user can see it at a glance and will not be wrong. In this way, only in the field of chemical industry can we ensure the compliance and good use of this product.
    Preparation Method
    The raw materials, production process, reaction steps and catalytic mechanism of 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid made today need to be studied in detail.
    First take an appropriate amount of 3-fluoro-5-hydroxyphenylboronic acid as the initial raw material, add isobutyl halide, use potassium carbonate as the acid binding agent, heat and stir in an organic solvent such as N, N-dimethylformamide, this is the nucleophilic substitution reaction step. The reaction temperature should be controlled between 80 and 100 degrees Celsius, and the reaction should be continued for about 6 to 8 hours. After the reaction is completed, cool to room temperature.
    The product was extracted with ethyl acetate, then dried with anhydrous sodium sulfate, and the desiccant was filtered to remove. The filtrate was spirally evaporated to remove the solvent to obtain a crude product. The crude product was separated and purified by column chromatography, and the mixture of petroleum ether and ethyl acetate was used as the eluent. The target fraction was collected, and the pure 3-Fluoro-5 - (Isobutoxy) Benzeneboronic Acid was spirally evaporated. During the whole process, the selection and dosage of catalysts, the control of reaction temperature and time all had a great impact on the purity and yield of the product, which required fine operation.
    Chemical Reactions & Modifications
    In the field of chemical industry, the research of 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid is related to chemical reaction and modification, which is the key.
    The method of reaction in the past may have complicated disadvantages, and the yield is not high. Now we want to change and improve the way of reaction. In the choice of catalyst, we should be careful to promote the reaction to speed up and improve the yield.
    Thinking about the modification of structure, we can explore the method of introducing other groups to change its properties and make it suitable for various new environments, such as pharmaceutical synthesis and material creation.
    Although there may be thorns in the road ahead, our chemical researchers, with the heart of research, should make unremitting exploration, and expect the reaction and modification of 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid to achieve a good environment and contribute to the progress of chemical industry.
    Synonyms & Product Names
    3-Fluoro-5- (isobutoxy) phenylboronic acid, this substance is very important in chemical research. Its synonyms and trade names have their own origins and have deep meanings.
    In today's chemical world, the search for the name of the substance is like tracing back to the long river of history. 3-Fluoro-5- (isobutoxy) phenylboronic acid, or another name, as the ancients called it, each has its own reference. Its trade name, taken by merchants, wants to show its characteristics, to distinguish it from other things.
    Synonyms, or according to the particularity of their structure, or according to the similarity of their properties, are determined by the research of many researchers. The trade name is related to the way of business, hoping to attract attention and emerge in the market.
    The beauty of chemistry lies in its fineness, and the difference between names is also its fineness. Synonyms and trade names, although they refer to one thing, they mean different things. We chemical researchers, we should study it in detail, in order to understand it, and move forward steadily on the road of chemistry.
    Safety & Operational Standards
    3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid Safety and Operation Specifications
    Husband 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid is an important material for chemical research. In order to operate, safety is essential, and it must be followed in order to protect it.
    The first word is safety. This compound has a certain chemical activity. If it is connected, it must be worn for protection. Those who wear clothes and wear anti-protective gloves can directly connect the skin to prevent chemical substances from invading the skin and causing skin damage. Wear eyes to prevent it from entering the eyes, eyes and eyes.
    Furthermore, the operation environment is also poor. It is recommended to use a good method of operation, so that the chemical waste can be quickly discharged, so as not to cause fatigue in the room and endanger the health of the patient. If there is a serious problem, it is necessary to use the help of communication to ensure proper handling.
    The operation should not be ignored. When using this product, it must be used with dry and dry equipment to prevent the mixture and affect its performance. Measure and select the product, and refine it according to the required dosage. If it is accidentally dropped, clean it up immediately. First cover it with suitable adsorption materials, collect it carefully, and then place it properly according to the method of chemical material management. Do not pour it out inadvertently to avoid polluting the environment.
    After use, store it properly. It should be placed in a dry, dry and transparent place, where there is no fire source and no source. The storage container is well sealed to prevent the contents of the empty container from reversing and causing alteration.
    Therefore, during the research operation of 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid, the safe operation is complete, and the two are mutually beneficial. Only by following this can the author conduct research and ensure their own safety and security.
    Application Area
    3-Fluoro-5- (isobutoxy) phenylboronic acid has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize compounds with specific pharmacological activities, paving the way for the development of new drugs. In the field of materials science, it may participate in the construction of functional materials, endowing materials with unique optical and electrical properties.
    In the art of organic synthesis, this compound can initiate a variety of chemical reactions and expand the structural diversity of organic molecules due to its structural properties. Through exquisite reaction design, complex and novel organic materials can be prepared, which have potential application value in many fields. The potential of its application is like a treasure that has not been fully explored. With the deepening of scientific research, it will surely bloom even more brilliantly.
    Research & Development
    I have been studying chemical substances for a long time. Recently, I have studied 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid. At first, I explored its properties, and found that its structure is unique and reactive. Then I studied its synthesis method. After many attempts, I improved the old method, optimized the process, and gradually increased the yield.
    The application of this substance has also been explored. It can be used as a key reagent in the field of organic synthesis to help form a variety of compounds, and has a broad prospect. I will continue to study it, tap its potential, expand the scope of application, and hope to contribute to the development of chemistry, add bricks and tiles, and promote its progress. It is used by academia and industry to reach new frontiers.
    Toxicity Research
    To study the toxicity of 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid, it is crucial to study its toxicity. Examine its properties and reaction characteristics in detail, and consider its performance in different media and conditions. After repeated experiments, use ancient methods to observe its role with various things, and identify whether it has a toxic change. Observe whether its toxicity changes under the influence of temperature, humidity and light factors. Also explore its route into the body of organisms and observe its impact on biological physiology. Although the experimental road is long, I uphold the heart of research, hoping to understand the toxicity of this chemical, in order to use it for safety and prevention, provide evidence, and prevent it from causing disasters to the world, so as to ensure the well-being of the people and the tranquility of the environment.
    Future Prospects
    Fu 3 - Fluoro - 5 - (Isobutoxy) Benzeneboronic Acid This product has great potential in today's chemical research. Looking at its molecular structure, the placement of fluorine and isobutoxy gives it unique characteristics.
    The future development can be deeply cultivated in medical research. With its structural characteristics, it may be able to create new drugs and open up new paths. The fit of drug targets may have subtle effects, adding powerful tools for treating diseases and treating diseases.
    And the field of chemical industry is also expected to shine. It can be used as a key raw material to help the research and production of high-end materials. With its characteristics, the material has excellent performance, such as better stability, reactivity, etc., which contributes to the progress of industry.
    Although it is currently in the process of research and development, I believe that with time, it will be able to bloom, and it will become an important pillar in the future of science and industry, with unlimited possibilities.
    Where to Buy 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid in China?
    As a trusted 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid?
    3-Fluoro-5- (isobutoxy) phenylboronic acid, a key raw material for organic synthesis, is widely used in many fields such as medicine, pesticides, and materials science.
    In the field of medicine, it is mainly used as a key intermediate to synthesize drug molecules with novel structures and specific biological activities. The development of many modern drugs relies heavily on such organoboron compounds. Due to its unique chemical properties, it can participate in a variety of chemical reactions and help build complex drug molecular structures. Through specific chemical reactions, 3-fluoro-5- (isobutoxy) phenylboronic acid can precisely combine with other organic molecules to generate compounds with unique pharmacological activities. For example, in the development of some anti-tumor drugs, this compound can be used as an important building block to participate in the construction of active structures that specifically bind to tumor cell targets, providing an effective way for the creation of anti-tumor drugs.
    In the field of pesticides, it also plays an important role. It can be used as a key raw material for the synthesis of high-efficiency, low-toxicity and environmentally friendly pesticides. Through rational chemical modification and reaction, incorporating it into the molecular structure of pesticides can significantly improve the activity and selectivity of pesticides to target organisms. For example, when synthesizing new insecticides, the unique reactivity of 3-fluoro-5- (isobutoxy) phenylboronic acid is used to construct a structure that binds to specific receptors in the insect nervous system, achieving efficient killing of pests while reducing the impact on non-target organisms, which is in line with the current development trend of green pesticides.
    In the field of materials science, this compound can be used to prepare functional organic materials. With its boron atom properties, it can participate in the construction of the molecular structure of the material, giving the material unique optical, electrical and other properties. For example, in the preparation of organic optoelectronic materials, the introduction of polymer structures can adjust the electronic transport and luminescence properties of materials, providing new opportunities for the development of organic Light Emitting Diodes (OLEDs), organic solar cells and other fields, and helping to develop new materials with better performance.
    What are the physical properties of 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid
    3-Fluoro-5- (isobutoxy) phenylboronic acid is an important raw material for organic synthesis and is widely used in medicinal chemistry, materials science and other fields. Its physical properties are unique and related to the reactivity and product characteristics of the synthesis process.
    The appearance of this compound is often white to light yellow solid powder, which is stable under normal conditions. This stability makes storage and transportation more convenient. However, its stability is also affected by environmental factors. High temperature, high humidity or contact with specific chemicals may cause decomposition or deterioration, so it should be properly stored in a dry and cool place.
    3-fluoro-5- (isobutoxy) phenylboronic acid has a certain solubility, and it has good solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). This property is conducive to its participation in various organic reactions. Because it can be uniformly dispersed in the reaction system, the reaction can be carried out efficiently. However, its solubility in water is limited, which limits its application in aqueous reactions.
    Its melting point is also a key physical property. After measurement, the melting point is in a specific temperature range, which can help to identify and judge the purity. Those with high purity have a narrow melting point range and are close to the theoretical value; when impurities are contained, the melting point decreases and the melting range widens.
    In addition, the moderate density of the compound is not a key factor affecting its chemical properties, but it has practical significance in large-scale production and preparation process, which is related to material measurement and reaction system ratio.
    In summary, the physical properties of 3-fluoro-5- (isobutoxy) phenylboronic acid, such as appearance, stability, solubility, melting point and density, have a profound impact on its storage, transportation and application in organic synthesis. In-depth understanding of these properties can provide a basis for its rational use and process optimization.
    What are the synthesis methods of 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid
    The synthesis method of 3-fluoro-5- (isobutoxy) phenylboronic acid has been known for a long time, and now it is the way for you.
    First, 3-fluoro-5-hydroxyphenylboronic acid and isobutyl halide are used as raw materials, and the two are combined in an alkaline environment. First take an appropriate amount of 3-fluoro-5-hydroxyphenylboronic acid, put it in the reactor, and add an appropriate amount of alkali, such as potassium carbonate, to help the reaction proceed. Then slowly add isobutyl halide, the activity of the halide is very critical, and the reaction speed is also the activity of the halogen atom. In this alkaline medium, the oxygen atom of the hydroxyl group is enhanced in nucleophilicity, and it is easy to attack the carbon atom of the isobutyl halide. The halogen atom leaves, and then forms 3-fluoro-5- (isobutoxy) phenylboronic acid. During the reaction, the temperature needs to be controlled. If the temperature is too high, the side reaction will occur, and if it is too low, the reaction will be slow. A moderate temperature is appropriate.
    Second, 3-fluoro-5- (halogenated phenoxy) phenylboronic acid is used as the starting material and is nucleophilically substituted. First, the halogenated phenoxy group reacts with the isobutyl alcohol under specific conditions. The hydroxyl group of isobutyl alcohol and the halogenated phenoxy group of During the reaction, a suitable catalyst needs to be selected to promote the efficient progress of the reaction. In this process, the choice of solvent is also important. A suitable solvent can increase the solubility of the reactants and help the smooth reaction. After this nucleophilic substitution reaction, the halogen atom is replaced by the isobutoxy group, and the final product is 3-fluoro-5- (isobutoxy) phenylboronic acid.
    Third, starting from 3-fluoro-5- (methoxy) phenylboronic acid, after substitution. First try to make the methoxy group leave, and specific reagents and conditions can be used to make the methoxy group become a group that is easy to leave. The target product is obtained by the reaction of isobutyl alcohol or its derivatives with isobutyl partially replacing the position of the original methoxy group. This process requires strict reaction conditions, and the dosage of reagents, reaction time and temperature need to be carefully controlled to obtain 3-fluoro-5- (isobutoxy) phenylboronic acid with higher yield.
    What to pay attention to when storing 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid
    3-Fluoro-5 - (isobutoxy) phenylboronic acid, this is an important organic compound. When storing, it is necessary to pay attention to many key matters.
    Bear the brunt, and temperature control is essential. It should be stored in a cool place, never in a high temperature environment. Due to high temperature, it is easy to cause chemical reactions of the compound, or accelerate its decomposition process, which will damage its chemical properties and purity. If the temperature is too high, it may damage the molecular structure, making it unable to play its due role in subsequent chemical reactions.
    Furthermore, humidity cannot be ignored. It should be stored in a dry place to avoid moisture. Moisture easily interacts with the compound, or causes adverse reactions such as hydrolysis. Once damp, it may change its chemical composition and affect its quality and stability.
    Shading is also a key measure. The energy in the light may induce photochemical reactions, which will have adverse effects on the structure and properties of the compound. Therefore, it should be stored in an opaque container to prevent light exposure.
    In addition, the storage place should be well ventilated. Good ventilation can prevent the accumulation of excess gas due to the evaporation of the compound, reduce potential safety risks, and avoid dangerous situations such as explosions.
    At the same time, it is also necessary to pay attention to its isolation from other substances. This compound may react chemically with certain substances, so it must be stored separately, away from oxidants, acids, bases, and other substances that may react with it, so as to ensure the safety and stability of its storage, so that it can retain good chemical properties and reactivity when used.
    What is the market price of 3-Fluoro-5- (Isobutoxy) Benzeneboronic Acid
    I look at this question, and I am inquiring about the market price of 3-fluoro-5- (isobutoxy) phenylboronic acid. However, the price of this chemical is difficult to determine. It is influenced by many factors, which are unpredictable and unpredictable.
    First, the price of raw materials. The synthesis of this chemical requires specific raw materials. If the price of raw materials fluctuates, the price of finished products will also fluctuate. If raw materials are scarce, or due to weather, geographical location, and man-made reasons, the price of 3-fluoro-5- (isobutoxy) phenylboronic acid will also rise; conversely, if raw materials are abundant and the price drops, the price of finished products may also decrease.
    Second, the cost of production. Including manpower, equipment, energy consumption and other items. If labor wages increase, equipment maintenance costs rise, and energy consumption costs increase, the total cost of production will increase, thereby pushing up the price of the chemical.
    Third, the supply and demand of the market. If there are many buyers, the demand exceeds the supply, and the chemical will become a popular item, and the price will rise; if the market is saturated and the supply exceeds the demand, the merchant may reduce the price in order to sell.
    Fourth, the difference between manufacturers. Different manufacturers, due to different technical levels, production scale, and management efficiency, have different production costs and product quality, which will also make prices different. Large manufacturers may have lower costs due to economies of scale, while small manufacturers may have higher prices due to their high-quality products.
    To sum up, in order to know the exact market price of 3-fluoro-5- (isobutoxy) phenylboronic acid, it is necessary to carefully investigate the trend of raw material prices, changes in the cost of each link of production, the situation of market supply and demand, and the specific quotations of each manufacturer, in order to obtain a more accurate number, which cannot be generalized.