3-Fluoro-5-hydroxyphenylboronic acid, this substance has outstanding functions in the field of medicinal chemistry. First, it is often used as a key intermediate in the process of drug synthesis. The structure of phenylboronic acid can be cleverly connected with many compounds through specific reactions, helping to build complex and delicate drug molecular structures. For example, when developing anti-tumor drugs, through its reaction with compounds containing specific functional groups, new anti-cancer drugs with unique mechanisms of action and precise targeting can be created.
Furthermore, in the field of materials science, it also has extraordinary performance. In the preparation of optical materials, it can participate in the reaction and endow the material with unique optical properties, such as improving the fluorescence properties of the material, so that the material exhibits better luminous efficiency and color purity in optoelectronic devices, such as organic Light Emitting Diode (OLED).
is also indispensable in the field of chemical analysis. It can specifically bind to compounds containing cis-diol structures, and with this property, it can be used for the separation and detection of carbohydrates, nucleotides and other substances. For example, in the analysis of carbohydrates in biological samples, 3-fluoro-5-hydroxyphenylboronic acid can be used as an identification element to achieve efficient enrichment and accurate determination of carbohydrates, providing a powerful tool for biochemical research and disease diagnosis.
In addition, in organic synthetic chemistry, as an organoboron reagent, it participates in many important reactions, such as the Suzuki-Miyaura coupling reaction. Through such reactions, carbon-carbon bonds can be formed, which greatly enriches the variety of organic compounds and lays a solid foundation for the development of new organic materials and drugs.

The synthesis methods of 3-fluoro-5-hydroxyphenylboronic acid have been discussed throughout the ages. One of the common synthesis methods is to use fluorophenols as starting materials. First, fluorophenols and halogenated boranes interact under appropriate reaction conditions. This reaction requires a suitable solvent, such as anhydrous ether or tetrahydrofuran, to facilitate the reaction. At the same time, the reaction system needs to be protected by low temperature and inert gas to ensure a smooth and effective reaction. Halogenated boranes can be selected according to the actual situation, such as boron tribromide or boron trichloride, etc. Both have their own advantages and disadvantages, and need to be determined according to the specific reaction requirements.
The second method uses phenylboronic acid derivatives as starting materials. The specific position of the phenylboronic acid derivative is modified first, and a fluorine atom is introduced, which can be achieved by nucleophilic substitution reaction. Then, a hydroxylation reaction is carried out at another position. This two-step reaction requires quite strict reaction conditions. When introducing fluorine atoms, a fluorine substitution reagent with suitable activity needs to be selected, and the reaction temperature and time should be precisely controlled; when hydroxylating, a suitable oxidant and catalyst need to be selected to obtain the ideal yield and selectivity.
Furthermore, there are also methods for synthesis by metal-catalyzed coupling reaction. Such as Suzuki coupling reaction, fluorohalogenated aromatics can be coupled with borate esters under the action of metal catalysts (such as palladium catalysts), and then hydrolyzed to obtain the target product 3-fluoro-5-hydroxyphenylboronic acid. In this process, the type and dosage of palladium catalysts, the type of base and the reaction solvent all have great influence on the reaction, and fine regulation is required to obtain satisfactory results.

3-Fluoro-5-hydroxyphenylboronic acid has unique physical properties. Looking at its physical properties, it is mostly white to quasi-white solid at room temperature, which is due to the intermolecular force. Its melting point is within a specific range, due to the interaction of various atoms in the molecular structure, resulting in a certain range of lattice energy, so it has this melting point performance.
As for the chemical properties, because it contains boron atoms and is connected to hydroxyl and fluorine atoms, it shows unique chemical activity. Boron atoms have electron-deficient properties, so this compound can participate in many chemical reactions as Lewis acids. The presence of hydroxyl groups allows it to participate in esterification, etherification and other reactions. Hydroxyl groups can provide lone pairs of electrons to interact with electrophilic reagents. Fluorine atoms have an impact on the electron cloud density distribution of the benzene ring due to their high electronegativity, which in turn affects the activity and selectivity of electrophilic substitution reactions on the benzene ring.
Furthermore, this compound has a wide range of uses in the field of organic synthesis and is often used as a key intermediate. With its unique physical and chemical properties, it can construct complex organic molecular structures, and is of great value in many disciplines such as medicinal chemistry and materials science.

Looking at this question, I am inquiring about the market price of 3-fluoro-5-hydroxyphenylboronic acid. However, the market price often changes due to many factors, and it is difficult to draw a conclusion.
In the past, in the chemical market, the price of materials often changed according to the state of supply and demand, the distance of origin, and the quality. If the demand for this product is strong and the supply is scarce, its price will increase; if the origin is close and the transportation cost is saved, the price may drop; and if the quality is high and it can meet the needs of many users, the price is also different.
3-fluoro-5-hydroxyphenylboronic acid is often used in organic synthesis, pharmaceutical research and development, etc. In organic synthesis, it can be a key reagent, participating in many reactions, and constructing special molecular structures. In pharmaceutical research and development, or as a raw material for lead compounds, it is related to the creation of new drugs.
To know the exact market price, visit the chemical raw material supplier. In today's world, information is convenient, you can search on the Internet or inquire by phone. Suppliers are different, and the quotations are also different. Or participate in industry exhibitions and communicate with merchants to know the market. Generally speaking, the price of this product may vary depending on the quantity, and those with large batches often enjoy discounts. And the market is changeable, and prices rise and fall from time to time. You need to pay attention in real time to know the situation.

When storing and transporting 3-fluoro-5-hydroxyphenylboronic acid, pay attention to many things. This is a chemical substance with special properties. If you are not careful, it will cause disaster.
When storing, the first environment is dry. Because of its certain water absorption, if it is in a humid place, it is easy to come into contact with water vapor, causing it to deteriorate and affect quality. It should be placed in a dry, well-ventilated place, away from water sources and moisture, to keep it stable.
Temperature is also critical. This substance is quite sensitive to temperature, and it is not suitable for too high or too low. Usually it should be stored in a cool place and avoid direct sunlight. High temperature can cause it to decompose or accelerate chemical reactions, while low temperature may slow down the reaction rate, but under some extreme low temperature conditions, it may also change its physical state and damage its performance.
Furthermore, storage should pay attention to isolating the air. Some phenylboronic acid compounds will react with oxygen in the air, so they should be sealed and stored to reduce the chance of contact with air and maintain their chemical stability.
When transporting, the packaging must be solid and stable. Because it is a fine chemical, bumps and collisions on the way can cause damage to the packaging, which can lead to leakage. Packaging materials must have good compression and shock resistance to ensure that they are intact during transportation.
In addition, the transportation process should follow relevant regulations and standards. Because it may belong to the category of hazardous chemicals, transportation qualifications, labels, etc. must be strictly implemented in accordance with regulations to prevent safety accidents and ensure the safety of transportation personnel and the public. All of these should be paid attention to when storing and transporting 3-fluoro-5-hydroxyphenylboronic acid, and must not be ignored.