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3-Fluoro-5-Formylbenzeneboronic Acid

3-Fluoro-5-Formylbenzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    453548

    Name 3-Fluoro-5-Formylbenzeneboronic Acid
    Chemical Formula C7H6BFO3
    Molecular Weight 167.93
    Appearance White to off-white solid
    Melting Point 138 - 142 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Pka Value Around 8 - 9 (approximate value for boronic acid group)
    Stability Air - and moisture - sensitive
    Reactivity Reacts with nucleophiles, can participate in Suzuki - Miyaura coupling reactions

    As an accredited 3-Fluoro-5-Formylbenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3 - fluoro - 5 - formylbenzeneboronic acid packaged in a sealed, chemical - resistant vial.
    Storage 3 - fluoro - 5 - formylbenzeneboronic acid should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, as boronic acids can react with moisture and oxygen over time. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid chemical reactions.
    Shipping 3 - fluoro - 5 - formylbenzeneboronic acid is shipped with strict adherence to chemical safety regulations. It's carefully packaged in suitable containers to prevent breakage and leakage, ensuring safe transport to its destination.
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    3-Fluoro-5-Formylbenzeneboronic Acid 3-Fluoro-5-Formylbenzeneboronic Acid
    General Information
    Historical Development
    3-Fluoro-5-formylphenylboronic acid, the research and development process of this substance is really meaningful. At the beginning, chemists worked hard in the field of organic synthesis to obtain new aryl boronic acid compounds and expand the boundaries of organic synthesis.
    In the past, the method of organic synthesis was still simple, and it was difficult to produce such fluorine-containing and formyl-containing phenylboronic acids. However, the public was unyielding. After repeated experiments and adjustment of the reaction conditions, a breakthrough was finally achieved. From the initial exploration to the gradual improvement of the reaction mechanism and the optimization of the process, today's results have been achieved. Its development process is like the ancient sages who overcame obstacles and finally reached the realm of light, adding a powerful tool to the field of organic synthesis. It has extraordinary potential in medicine, materials and other fields. It is indeed a brilliant fruit of the journey of chemical exploration.
    Product Overview
    Today there is a substance called 3 - Fluoro - 5 - Formylbenzeneboronic Acid. Its shape is unknown, but in the field of chemistry, it has its own use. This substance has a unique structure. The fluorine atom is placed on the benzene ring with the aldehyde group and the boric acid group.
    Because of its specific structure, it may become a key building block in organic synthesis. The aldehyde group can participate in the condensation reaction, and the boric acid group can also be used in the coupling method to develop its function. And the introduction of fluorine atoms may make the compound different from the normal in terms of electronic effects and spatial effects, which is the direction of the reaction and the nature of the product, adding variables and increasing possibilities. In the field of pharmaceutical research and development and material creation, it may be possible to create new paths and achieve useful results based on its characteristics.
    Physical & Chemical Properties
    3-Fluoro-5-formylphenylboronic acid, this substance is also very different in nature. Looking at its shape, it is often white to off-white powder, fine and uniform. Its melting and boiling point is also characteristic. The melting point is about a certain range, which depends on the strength of the intermolecular force. The boiling point varies according to external pressure, and under standard pressure, it also has a certain value.
    In terms of its solubility, it is slightly soluble in common organic solvents such as ethanol, ether, etc. This is because the molecular structure contains polar and non-polar parts, which interact differently with solvent molecules. And its chemical activity is quite considerable. Formyl groups and boric acid groups are active groups that can react with many reagents and can be used in key steps of organic synthesis to construct complex compound structures. The physicochemical properties of this substance are an important foundation for organic chemistry research and have potential application value in materials science, drug development and other fields.
    Technical Specifications & Labeling
    There are chemical substances today, named 3 - Fluoro - 5 - Formylbenzeneboronic Acid. In the process specification and identification (product parameters), it is quite important.
    Its process specification must be precise and strict. From the selection of raw materials, the quality must be high and pure, and the impurities must be few. When preparing, temperature control, time control, and pressure control should not be ignored. The reaction device is clean and suitable, and foreign objects should be prevented from disturbing it. Each step, according to established regulations, cannot be changed without authorization.
    As for the identification (product parameters), state its nature. If the color state, it should be detailed; the purity geometry must be accurate; the molecular weight, melting point, boiling point, etc., all need to be clear. The method of use, storage and transportation should also be indicated. In this way, the product can be used by the user without error and safely, and it can be orderly and smooth in the process of craftsmanship.
    Preparation Method
    The raw materials and production process, reaction steps and catalytic mechanism of this 3-Fluoro-5-Formylbenzeneboronic Acid are the key.
    The raw materials are selected, and fluorobenzaldehyde and borate esters are taken as the base. The active check point of fluorobenzaldehyde and the active site of borate esters can initiate the reaction.
    The production process, in an inert atmosphere, dissolves in organic solvents, such as toluene, dichloromethane, etc., which can promote the collision and reaction of the two molecules. Warm up to a suitable temperature, about 60-80 degrees Celsius, and the temperature control is accurate to facilitate a smooth reaction.
    The reaction step is to mix fluorobenzaldehyde and borate evenly, and add an appropriate amount of alkali as a catalyst, such as potassium carbonate. The function of alkali is to activate the two, so that the reaction is easy to start. After several times of reaction, when the color and composition of the system are stable, it is measured by thin-layer chromatography, and the reaction is complete.
    Catalytic mechanism, the alkali helps the fluorobenzaldehyde carbonyl α-hydrogen to leave, generating carbon negative ions. This nucleophilic body attacks the boron atom of borate ester and forms an intermediate state. After hydrolysis and other steps, 3-Fluoro-5-Formylbenzeneboronic Acid can be obtained. After these steps, high-purity products can be obtained.
    Chemical Reactions & Modifications
    To taste the wonders of chemical industry, it is related to the change of substances. The way of reaction and modification of this compound in 3-Fluoro-5-Formylbenzeneboronic Acid can be studied.
    To observe its reaction, the chemical method is to be precise. Or temperature regulation, or agent selection, to achieve the best situation. However, the difficulty of reaction often lies in the by-product impurities, which disturb the pure product. To solve this problem, it is necessary to study the mechanism in depth and observe the physical properties in detail.
    As for modification, it is to increase its properties and widen its use. Or introduce new radicals and change its structure to suit different needs. However, modification is not easy, and the advantages and disadvantages must be weighed to prevent one from losing the other.
    Our generation should inherit the wisdom of the ancient sages, study its chemical changes with diligence, and make the reaction and modification of this compound increasingly perfect, contributing to the prosperity of chemical industry.
    Synonyms & Product Names
    Today there is a thing called 3 - Fluoro - 5 - Formylbenzeneboronic Acid. Although its names are different, there are also many synonymous names. The names of chemical things are complicated, and the names of synonyms vary depending on different academic schools, regional habits, or research focuses.
    This substance is in the field of chemical industry, or has the name of a different product. In order to recognize its characteristics, or to facilitate market circulation, merchants often take a unique trade name. The synonymous name also helps scholars to communicate accurately, so that everyone knows what it refers to.
    For us chemical researchers, we can study the synonymous names and trade names of this thing carefully, so that we can be correct and smooth when researching and applying it. Accurately grasping its title is the cornerstone of exploring chemical mysteries and promoting chemical development.
    Safety & Operational Standards
    3-Fluoro-5-formylphenylboronic acid is an important chemical substance that is widely used in many fields of chemical research and industrial production. To ensure its safe production, use and storage, detailed safety and operating practices are indispensable.
    The first part of the safety section, this substance has certain chemical activity, or may be potentially harmful to the human body and the environment. When coming into contact, be fully armed, wear protective clothing, protective gloves and goggles to avoid skin-to-eye contact. If you accidentally touch the skin, you should immediately rinse with plenty of water and seek medical attention as appropriate; if you splash into the eyes, you need to rinse with plenty of water quickly and seek medical attention as soon as possible. In the process of use, also beware of inhaling its dust or volatile aerosol, so the operation is suitable in a well-ventilated place, or with the help of ventilation equipment and gas masks.
    As for the operation specifications, when storing, it should be placed in a cool, dry and well-ventilated warehouse, away from fire, heat sources, and protected from direct sunlight. At the same time, it should be stored separately from oxidants, acids, and alkalis, and should not be mixed to prevent dangerous chemical reactions. When using this substance, be sure to use clean and dry appliances, and strictly control the dosage according to experimental procedures or production requirements to avoid waste or safety accidents. After the operation is completed, clean and properly store the appliances used in time, and clean the operating table to ensure a clean working environment.
    When transporting this product, it is also necessary to follow relevant regulations, take protective and fixed measures to prevent collisions and leaks, and ensure the safety during transportation. Only by strictly adhering to safety and operating standards can 3-fluoro-5-formylphenylboronic acid be used in scientific research and production to play its due role, while minimizing latent risks.
    Application Area
    Today there is a thing called "3 - Fluoro - 5 - Formylbenzeneboronic Acid", which is very useful in various fields. In the field of medicine, it can be used as a key intermediate to help synthesize special drugs and heal diseases. Chemists carefully prepare it to combine with other things to obtain ingredients with unique curative effects. In the material industry, this compound can improve the properties of materials. Or enhance its stability, make the utensils durable; or give it special optical properties, applied to optoelectronic devices. And in the path of scientific research and exploration, it provides scholars with new research paths to help them gain insight into microscopic mysteries and open up unknown territories. All of these highlight the broad application world of "3 - Fluoro - 5 - Formylbenzeneboronic Acid", which has contributed to the development of many industries and has great prospects.
    Research & Development
    I have been dedicated to the research of 3 - Fluoro - 5 - Formylbenzeneboronic Acid for a long time. This compound has unique chemical properties and has great potential in the field of organic synthesis.
    At the beginning, we explored its synthesis path, and after various attempts, we found an effective method. After many optimizations, the yield gradually increased and the quality stabilized.
    Then, study its reactivity. Examine its interaction with various reagents, explore the reaction mechanism, and demonstrate its key role in the construction of complex organic structures.
    Our generation knows that only by unremitting research can we make progress in chemistry. It is hoped that in the future, this compound can open up a new world for many fields such as organic synthesis and drug research and development, promote the development of science, and benefit the world.
    Toxicity Research
    Today there is a product, named 3 - Fluoro - 5 - Formylbenzeneboronic Acid. I am a chemical researcher, focusing on its toxicity research. The nature of this product is related to the safety of everyone and cannot be ignored.
    Examine this 3 - Fluoro - 5 - Formylbenzeneboronic Acid in detail, explore its reaction in different environments, and observe the changes caused by its integration with other things. Observe its impact on organisms, test it with various organisms, and observe its physiological and behavioral changes.
    After many experiments, we know where its toxicity lies. It may damage the structure of biological cells and disrupt the order of their metabolism; or disturb nerve conduction and cause behavioral disorders. Although it is widely used, its toxicity cannot be underestimated. We must be careful again and again, study proper methods, avoid harm and take advantage of it, so as to ensure the well-being of everyone and the safety of the environment.
    Future Prospects
    Wuguanfu 3 - Fluoro - 5 - Formylbenzeneboronic Acid is unique and has a wide range of uses. In today's world, although it has been studied, the future prospects are still grand.
    In the future, it may be able to shine in the field of medicine. With its unique structure, it may help to develop new medicines, cure various difficult diseases, and save patients from pain.
    In materials science, it is also expected to open up new frontiers. It may give birth to novel functional materials for high-end technology products and improve the performance of equipment.
    In addition, it is used in chemical synthesis, or as a key agent to optimize the synthesis path, improve yield, reduce cost and increase efficiency.
    Our scientific researchers should study diligently, with a view to developing the potential of this thing in the future, and open up endless possibilities for human well-being.
    Where to Buy 3-Fluoro-5-Formylbenzeneboronic Acid in China?
    As a trusted 3-Fluoro-5-Formylbenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Fluoro-5-Formylbenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 3-fluoro-5-formylphenylboronic acid
    3-5-methylbenzylfuranoic acid, which is mostly used in chemical industry.
    In this field, it is important for the synthesis of polymers. For example, some antibacterial compounds, such as 3-5-methylbenzylfuranoic acid, can be introduced into specific molecules to increase the antibacterial activity of polymers. Some of the parts such as polybutylfuranoic acid can interact with specific targets of bacteria, or inhibit the enzyme activity of bacteria, or dry the cell wall synthesis of bacteria, so as to achieve antibacterial effect.
    In the chemical industry, 3-5-methylbenzylfuranic acid can be used as a functional component. Because of its certain antioxidant properties, it can capture free radicals on the surface of the skin, reduce the oxidation process of the skin, and prevent skin aging. For example, when added to face creams, fertilizers, etc., it can make the skin healthy and keep the skin smooth. In addition, it may have a certain anti-inflammatory effect. It can be used in some micro-skin inflammation. It can be used in sensitive muscle products to reduce skin sensitivity and improve skin comfort.
    What are the synthesis methods of 3-fluoro-5-formylphenylboronic acid?
    The synthesis of 3-hydroxyl-5-methylbenzoic acid involves many ingenious pathways.
    One of them can be acylated by Friedel-Crafts. Using anisole as the starting material, the acylation reaction is carried out with isophthalic anhydride under the catalysis of Lewis acids such as anhydrous aluminum trichloride. During this process, Lewis acid activates the anhydride, causing it to undergo electrophilic substitution with anisole to generate corresponding acylation products. Subsequent to the appropriate demethylation step, such as the conversion of methoxy group to hydroxyl group under the action of reagents such as hydrobromic acid, the target product 3-hydroxy- 5-methylbenzoic acid is obtained.
    Second, it can also start from m-methylbenzoic acid. First, through halogenation reaction, under the action of suitable halogenating reagents such as bromine, halogen atoms are introduced at specific positions in the benzene ring, and then reacted with Grignard reagents. The halogen-containing intermediate is reacted with magnesium to form Grignard reagents, and then reacted with corresponding carbonyl compounds to construct a benzoyl structure. Finally, the relevant groups are converted into carboxyl groups through oxidation and other steps to achieve the synthesis of 3-hydroxyl-5-methylbenzoylbenzoic acid.
    Furthermore, the route using m-toluene as the starting material can also be used. The phenolic hydroxyl group is properly protected to prevent it from interfering in subsequent reactions. Then the benzoyl fragment is introduced through an acylation reaction, and suitable acylation reagents and catalysts can be used. After the acylation is completed, the protective group is removed, and then the carboxylation reaction is carried out. Under suitable conditions, such as in a carbon dioxide atmosphere and under the action of a specific catalyst, the carboxyl group is introduced to successfully synthesize 3-hydroxy- 5-methylbenzoylbenzoic acid. All methods have their own advantages and disadvantages, and they need to be selected according to the actual situation.
    What are the physical and chemical properties of 3-fluoro-5-formylphenylboronic acid?
    3-Hydroxy-5-methylglutarate monoyl-coenzyme A is a key intermediate product of lipid metabolism in the human body. Its physical and chemical properties are unique and significant in biochemical processes.
    This substance is mostly white to off-white crystalline powder at room temperature, with fine texture. Looking at its solubility, it is slightly soluble in water. This property allows it to exist stably at a specific concentration in the aqueous environment of organisms and participate in various biochemical reactions. And because its structure contains both hydrophilic and hydrophobic groups, it can accurately locate to specific organelles or biofilm regions in the complex microenvironment of cells, playing a key role.
    When it comes to chemical stability, under conventional physiological conditions, its structure is relatively stable, and it can resist a certain degree of acid-base changes and mild redox environment, ensuring that it can participate in various enzymatic reactions in an orderly manner during metabolism in the body. In case of extreme acid-base or strong redox conditions, its structure may be damaged, affecting the normal metabolic pathway.
    From chemical structure analysis, 3-hydroxy- 5-methylglutarate monoyl coenzyme A contains special functional groups such as carboxyl groups, hydroxyl groups and thioester bonds. The carboxyl group makes it acidic and can participate in the regulation of acid-base balance and related ion exchange processes; the hydroxyl group can interact with other biomolecules through hydrogen bonds to enhance the recognition and binding ability between molecules; and the thioester bond contains high energy, which acts as an energy carrier in the metabolic process, breaks and releases energy under the action of specific enzymes, driving important biochemical reactions such as cholesterol synthesis.
    Such unique physical and chemical properties make 3-hydroxy- 5-methylglutarate monoyl-coenzyme A occupy a core position in the lipid metabolism network in life, and are of great significance for maintaining the normal physiological function of the body.
    What are the precautions for 3-fluoro-5-formylphenylboronic acid during storage and transportation?
    There are many things to pay attention to during the storage and transportation of 3-metaphase-5-methylbenzylnaphthalenesulfonic acid. This substance has certain chemical activity, so when storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent chemical changes due to temperature, humidity and other factors, or even cause danger. Because it may be corrosive to some materials, the material of the storage container used must be appropriate. Generally, corrosion-resistant materials should be selected, such as specific plastic or glass containers, and the containers must be tightly sealed to avoid reactions such as oxidation caused by excessive contact with air.
    When transporting, a high degree of caution should also be taken. Transport vehicles need to have stable driving conditions to prevent package damage due to bumps and vibrations. Packaging must be firm and reliable, in addition to leak-proof, it should also be able to withstand certain external shocks. And, transport personnel should be familiar with the characteristics of this chemical and emergency treatment methods, in case of leakage and other situations, can quickly and correctly respond. At the same time, the transportation process must strictly follow relevant regulations and standards, and handle necessary transportation licenses and procedures to ensure legal compliance of transportation. In addition, key information such as the name, characteristics, hazards, and emergency treatment measures of the substance should be clearly marked on the transportation documents and packaging labels, so that all parties can know it, so as to ensure its stability and safety in all aspects when storing and transporting 3-Bifurcation-5-methylbenzylnaphthalenesulfonic acid and prevent accidents.
    What is the market price trend of 3-fluoro-5-formylphenylboronic acid?
    In today's world, in the market, the price of 3-5-methylbenzylfuranic acid is not enough, and the price is not enough. The city is not enough, and the flow of water is affected by the same reasons.
    The supply and demand of this product is not enough. If the demand for this product is arduous, and the supply is limited, it will not be enough. For example, if a certain industry is now in use, the demand for 3-5-methylbenzylfuranic acid will increase, and the demand will not be increased as fast as the speed, such as the price, straight up to the sky. On the contrary, if the supply is in demand, such as those who are used and those who are thin, the price will fall, just like the land.
    Furthermore, the cost is also low. The cost of materials, the cost of labor, and the cost of labor all depend on the cost. If materials are scarce, the cost is high, or the cost of labor is increased due to factors, and the road of transportation is blocked, resulting in high costs. The cost of construction is high, and the cost of construction has to rise in the city. On the contrary, if materials are low, the cost of labor is saved, and the cost is reduced.
    In addition, the cost of government orders and the cost of the bureau can also be reduced. If the government encourages the cost of this thing and provides support, the amount may be increased, or it may be flat. In the event of a world where trade routes are blocked, or where supplies are made, the city will not live.
    Therefore, the market of 3-5-methylbenzylfuranoic acid is not acceptable. It is necessary to consider supply and demand, costs, government decrees and other factors in order to obtain its general outline.