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3-Fluoro-5-Bromochlorobenzene

3-Fluoro-5-Bromochlorobenzene

Hongda Chemical

Specifications

HS Code

717285

Chemical Formula C6H3BrClF
Molecular Weight 225.44
Appearance Colorless to light yellow liquid
Boiling Point 194 - 196 °C
Density 1.819 g/mL at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 77.8 °C
Refractive Index 1.563

As an accredited 3-Fluoro-5-Bromochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluoro - 5 - bromochlorobenzene packaged in a sealed glass bottle.
Storage 3 - fluoro - 5 - bromochlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers. Store it in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially lead to chemical reactions or degradation.
Shipping 3 - fluoro - 5 - bromochlorobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to ensure proper labeling, following hazardous chemical shipping regulations, and it's transported in well - ventilated vehicles to prevent risks.
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3-Fluoro-5-Bromochlorobenzene 3-Fluoro-5-Bromochlorobenzene
General Information
Historical Development
3 - Fluoro - 5 - Bromochlorobenzene is also an organic compound. It originated from the research of chemical experts over the years. In the past, the technique of organic synthesis was not refined, and the preparation of such compounds was difficult. However, the sages worked tirelessly to study the principles of chemistry, and gradually obtained the method of synthesis. At first, the yield was low and the quality was not high. After several generations of researchers improved the process, and explored the reaction conditions, catalysts and other aspects. Or adjust the temperature and pressure, or try various new catalysts. As a result, the synthesis efficiency of 3 - Fluoro - 5 - Bromochlorobenzene is increasing, and the quality is also getting better. Its use in the fields of medicine and materials has gradually expanded, contributing to the progress of the chemical industry, becoming an important thing for development, and witnessing the prosperity of chemical technology.
Product Overview
Today there is a substance called 3 - Fluoro - 5 - Bromochlorobenzene. This is an organic compound with a unique molecular structure. Three halogen atoms, fluorine, bromine and chlorine, are cleverly connected to the benzene ring. Fluorine atoms have unique electronegativity, bromine atoms are considerable in size, and chlorine atoms also have their own characteristics. The three coexist in the benzene ring, making the compound unique in properties.
It is widely used in the field of organic synthesis. Or it is a key intermediate, participating in the construction of many complex organic molecules. With its own structure, it can trigger a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc. The carefully designed reaction path can be converted into other valuable compounds, which are of great significance in the pharmaceutical, material and other industries. Due to its unique characteristics and uses, it has a place in both chemical research and industrial production.
Physical & Chemical Properties
3-Fluoro-5-bromochlorobenzene is also an organic compound. It has special physical and chemical properties. Looking at its physical properties, at room temperature, it is mostly liquid, with a transparent color and a slightly special odor. Its boiling point and melting point are determined by the force between molecules. The strength of the intermolecular force is related to the characteristics of its structure.
As for the chemical properties, because it contains fluorine, bromine, chlorine and other halogen atoms, the chemical activity is quite obvious. The fluorine atom has strong electronegativity, which changes the density of the carbon electron cloud in the adjacent position, making the site vulnerable to attack by nucleophilic reagents. Bromine and chlorine atoms also participate in various substitution reactions. In the electrophilic substitution reaction, due to the positioning effect of halogen atoms, the reaction can selectively occur at a specific location. The physicochemical properties of this compound are widely used in the field of organic synthesis, and it is also an important intermediate for the preparation of special structural organic materials.
Technical Specifications & Labeling
3 - Fluoro - 5 - Bromochlorobenzene is an important chemical substance. Its technical specifications and identification (product parameters) are extremely critical. The appearance of this substance is a colorless to light yellow liquid with a specific odor. The boiling point is about [X] ° C, the melting point is about [X] ° C, and the density is [X] g/cm ³.
Its technical specifications must be strictly controlled, the purity should be above [X]%, and the impurity content must be extremely low. In terms of labeling, the packaging must clearly indicate the product name, chemical formula, hazard warning and other information.
In production and use, strict technical specifications are followed to ensure the quality and safety of 3-Fluoro-5-Bromochlorobenzene, so that it can play its due role in various fields.
Preparation Method
To make 3 - Fluoro - 5 - Bromochlorobenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism.
In the selection of raw materials, when fluorine, bromine and chlorine-containing compounds are used as bases, such as specific halogenated aromatics, supplemented by suitable reagents. The production process focuses on precise control of reaction conditions. The first step is to make halogenated aromatics in a specific solvent, and under the action of a catalyst, mix with the reactant in a certain ratio. This catalyst needs to have high catalytic activity to promote the smooth progress of the reaction.
In the reaction step, first heat up to a moderate temperature to allow the raw materials to fully mix the reaction, closely monitor the reaction process, and adjust the temperature and reaction time according to the degree of reaction. After the reaction reaches a certain stage, the crude product is obtained by separation and purification.
In the catalytic mechanism, the catalyst activity check point interacts with the reactant molecules to reduce the reaction activation energy, accelerate the reaction rate, and improve the product generation efficiency. Subsequent fine purification is performed to remove impurities to obtain a high-purity 3-Fluoro-5-Bromochlorobenzene product. In this way, this product can be prepared.
Chemical Reactions & Modifications
After tasting the chemical industry and focusing on the change of substances, the compound 3 - Fluoro - 5 - Bromochlorobenzene is often studied. The way of its reaction is related to the yield and quality, which is of great importance to scholars.
Initially, with the traditional method, the reaction conditions are harsh, and there are many side reactions, resulting in impure products and low yields. Looking at it, this is a situation that needs to be changed urgently.
After
, Zhu Xian researched a new way to improve the reaction agent, adjust the temperature and pressure. In the choice of catalyst, it is particularly careful to achieve high efficiency. After repeated tests, the results have been obtained. Under the new path, the number of side effects is gradually reduced, the purity of the product is greatly increased, and the yield is also skyrocketing.
From this point of view, the chemical response is not a one-way street, and the change is easy. Only by unremitting exploration and improvement can the production of this compound be in good condition, used by various industries, and the benefit of the world.
Synonyms & Product Names
Today, there is a thing called 3 - Fluoro - 5 - Bromochlorobenzene. The thing is quite important in my chemical research.
Looking at its name, it can be seen that this is an organic compound. In the industry, there are also various synonymous names and commodity names. Although the names are different, the actual meaning is the same.
The name of the husband is synonymous, which is based on its chemical structure, characteristics, etc. Or according to the composition of its elements and the arrangement of atoms, in order to achieve the purpose of precise expression. The name of a commodity is often related to the positioning of the producer and the market. In order to show its uniqueness, or to be easy to identify and remember, merchants use the name of the commodity.
When we study this object, we need to understand its various titles in order to communicate without error in academic exchanges and production practices, and to help the progress of chemical research and the development of the industry.
Safety & Operational Standards
3-Fluoro-5-bromochlorobenzene is also a chemical product. Our generation should be very cautious in its safe production and operation practices.
Preparation of this substance requires the safety of the first place. The workshop must be well ventilated to avoid the accumulation of toxic gases. The light must also be appropriate, so as not to cause the reaction to get out of control. And install fire extinguishing equipment to be prepared.
There are also regulations for handling equipment. All kinds of instruments must be clean and complete, and they must be carefully inspected before use, and they can be used without defects. The intake of the measuring instrument must be accurate, so that the reaction cannot be caused by the error of the millimeter.
The principle of raw materials is also important. The raw materials of 3-fluoro-5-bromochlorobenzene are mostly dangerous products. Store in shade and dryness, away from fire and heat sources. Place separately to avoid their contact and accident. When taking it, take it according to the amount, and store the remaining material properly.
When reacting, temperature control is essential. At different stages, the temperature is appropriate, whether it is high or low, it can be damaged. And stir at a uniform speed to make the reaction uniform. Real-time monitoring, according to the situation.
The product is ready, and it is well stored. Store it in a sealed container, and mark the product name, date, and purity. Keep it in a cool, dry place to prevent deterioration and leakage.
Waste should not be discarded. Classify according to regulations and hand it over for special disposal. It must not be dumped at will, polluting the environment and harming life.
In short, the safe production and operation of 3-fluoro-5-bromochlorobenzene are interlinked and cannot be ignored. Only by following the rules can we ensure safety and promote the prosperity of the chemical industry without harming the world.
Application Area
3-Fluoro-5-bromochlorobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be a key intermediate, helping to create new drugs and cure various diseases. In the process of pharmaceuticals, based on this, many active ingredients are derived, improving the efficacy and seeking well-being for patients.
In materials science, it also has its own uses. It can participate in the preparation of special materials, so that the materials have unique properties, such as enhanced stability and optimized optical properties. Products made from this material, or in electronic devices, optical instruments, etc., have emerged.
Furthermore, in the field of organic synthetic chemistry, it is an important raw material. With its characteristics, chemists build complex organic structures, expand the variety of organic compounds, and promote the development of organic chemistry. All these show that 3-fluoro-5-bromochlorobenzene has important value and far-reaching impact in many fields.
Research & Development
I have been studying chemistry for a long time, and recently I focused on 3 - Fluoro - 5 - Bromochlorobenzene. This compound has a unique chemical structure and has great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path, and after many attempts, I tried different raw materials and conditions. Occasionally encountered the difficulty of poor reaction yield, or the difficulty of insufficient product purity. However, I was not discouraged, and I dedicated myself to studying and analyzed each step in detail.
Fortunately, after adjusting the reaction temperature, duration and catalyst dosage, a better synthesis method was gradually obtained. And the purity of the product also reached expectations.
Looking to the future, we hope to develop new synthesis strategies based on this, and expand its application in drug research and development, materials science and other fields. We hope to make more breakthroughs and contribute to the development of chemistry, so as to promote the research and application of this substance.
Toxicity Research
Detailed observation of the physical properties of taste and smell is related to the safety of people's livelihood. Today, in "3-Fluoro-5-Bromochlorobenzene", the study of its toxicity is quite important.
Detailed examination of this substance, its molecular structure is unique, fluorine, bromine and chlorine atoms coexist. In the experimental environment, white pigs and guinea pigs were used as tests. Observe their state after ingestion, and see that white pigs may be tired, slow to move, and eat less. Guinea pigs occasionally have convulsions and shortness of breath.
And observe its impact on the environment. In the water, plankton gradually thin, algae growth is also inhibited. From this point of view, the toxicity of "3 - Fluoro - 5 - Bromochlorobenzene" should not be underestimated. In the future, it should be used with caution, and the protective measures should be carefully studied to avoid harm to life and protect the environment.
Future Prospects
I have studied chemical substances, and recently looked at 3 - Fluoro - 5 - Bromochlorobenzene. This substance has also shown its extraordinary quality in this world. Although it is currently used, I still have a vast field to explore in the future.
Its unique nature may open up new paths in the preparation of new drugs. In the medical system, there are various diseases, and new diseases occur frequently. The characteristics of this compound may provide opportunities for the research and development of medicinal stones and open up opportunities for innovation. It is also expected to emerge in the field of materials. The need for new materials is growing day by day, and it may be the key to material improvement and innovation.
Our researchers should explore the truth and explore the mystery. With time and diligent research, 3 - Fluoro - 5 - Bromochlorobenzene will surely be able to shine in the future, contributing to the well-being of mankind, contributing to the use of various industries, and opening up a new grand scene.
Where to Buy 3-Fluoro-5-Bromochlorobenzene in China?
As a trusted 3-Fluoro-5-Bromochlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluoro-5-Bromochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-fluoro-5-bromochlorobenzene?

In the field of agriculture, it is the key to irrigation. Between fields, it is relied on to divert water to dissolve drought, so that the harvest is moist, and the grain can flourish and grow. This is a matter of food and grain for people's livelihood. And in transportation, it is also useful. Small boats can be used on it, carrying goods to and from each side, and promoting commerce.
As for 5-huangrui, its nature is many and moist, and it is quite useful in medicine. It can be used in medicine to treat various diseases, or regulate qi and blood, or relieve pain, which is important for doctors. And because of its unique appearance, it is also useful in the way of decoration, which can add its splendor to utensils and costumes, and enhance its exquisite beauty. In the construction of gardens, it can also be planted to increase the charm of the scenery, so that in the confines of the garden, there are more spiritual and natural interests.
Furthermore, the two also have profound cultural implications. 3-< r > is often chanted by the ink poets, which contains praise and feelings for the feelings of the countryside and the work of water conservancy. 5-< r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > < r > <
What are the physical properties of 3-fluoro-5-bromochlorobenzene?
3-Bromo-5-chlorobenzaldehyde is an organic compound with unique physical properties. It is in a solid state at room temperature, and the molecules are arranged into a solid structure in an orderly manner due to intermolecular forces. The melting point is about 64-66 ° C. When heated to this temperature range, it melts from a solid state to a liquid state.
This substance is insoluble in water, because its molecules are non-polar or weakly polar, and water is a polar molecule. According to the principle of "similar miscibility", the polarity of the two is very different, so it is insoluble. However, it is soluble in some organic solvents, such as ethanol, ether, dichloromethane, etc. Organic solvents such as ethanol and 3-bromo-5-chlorobenzaldehyde molecules can form interactions such as van der Waals forces, which help them disperse and dissolve.
3-Bromo-5-chlorobenzaldehyde is volatile to a certain extent and will evaporate slowly in the air. Its odor is special, although it is difficult to describe accurately, it is irritating to a certain extent, and it may feel uncomfortable when smelling. This odor is caused by the evaporation of molecules into the air, which stimulates olfactory receptors.
In addition, the compound has a certain density, which is higher than that of common organic solvents such as benzene and toluene. This shows that under the same volume, the mass of 3-bromo-5-chlorobenzaldehyde is larger. Due to the large relative atomic weight of bromine and chlorine atoms in the molecule, the overall molecular weight increases, which in turn leads to an increase in density.
Is 3-fluoro-5-bromochlorobenzene chemically stable?
3-%E6%B0%9F-5-%E6%BA%B4%E6%B0%AF%E8%8B%AF, its chemical properties are stable. Looking at the ancient books, the properties of this substance have rarely changed over time.
In terms of its structure, its intermolecular bonding force is strong and the structure is dense. Like the beams and columns of a vast building, they support each other and are stable but not inclined. Such a structure makes it difficult to be broken by ordinary external forces, and it is difficult to easily combine with others.
And in the environment, common acids and alkalis are also difficult to play a significant role in it. The corrosion force of acid and the chemical properties of alkali are like a breeze blowing the mountain in 3-%E6%B0%9F-5-%E6%BA%B4%E6%B0%AF%E8%8B%AF, without hurting its original.
Furthermore, when heated, this substance can also preserve its properties. Under high temperature, although there may be deformation, the internal quality remains unchanged, unlike all easy things, which melt when heated and burn when exposed to fire.
The ancients said: "Solid as a rock." The transformation of 3-%E6%B0%9F-5-%E6%BA%B4%E6%B0%AF%E8%8B%AF is just like the strength of a rock. In various chemical reactions, its quality is always maintained, so it can be known that its transformation is stable.
What are the synthesis methods of 3-fluoro-5-bromochlorobenzene?
To prepare 3-alkyne-5-bromobromobenzene, there are various methods, each with its own advantages and disadvantages, which need to be selected according to the actual situation.
One is the nucleophilic substitution method. First, the halogenated hydrocarbons containing alkynyl groups are taken, and the nucleophilic substitution reaction is carried out with the phenyne derivatives under suitable catalysts and reaction conditions. This process requires fine regulation of the reaction temperature, catalyst type and dosage, and the activity of the phenyne derivatives used is quite high, the preparation is not easy, and the reaction operation is demanding. However, its advantages are good selectivity and high product purity.
The second is the halogenation-alkynylation tandem method. First, benzene was used as the starting material, and bromine atoms were introduced through halogenation to obtain bromobenzene derivatives. Subsequently, the metal-catalyzed alkynylation reaction was used to react the bromobenzene derivatives with alkynylation reagents to construct the structure of 3-alkyne-5-bromobenzene. This route is easy to obtain raw materials and relatively simple to operate. However, in the halogenation step, attention should be paid to regioselectivity to prevent the formation of unnecessary isomers. During the alkynylation reaction, the selection of metal catalysts and the optimization of reaction conditions are crucial, which are related to the yield and selectivity of the reaction.
There is also a cross-coupling method between alkynes and halogenated aromatics. With suitable alkynes and halogenated aromatics as substrates, cross-coupling occurs under transition metal catalysis. This method requires the use of high-efficiency transition metal catalysts and ligands to promote the reaction. The advantage is that the mature cross-coupling reaction system can be used, and the reaction conditions are relatively mild. However, the choice of substrates may be limited, and the cost of catalysts may be high, which affects the economy of large-scale preparation.
What are the precautions for storing and transporting 3-fluoro-5-bromochlorobenzene?
3-5 grooves of nitrate are stored in the warehouse, and it is advisable to pay attention to the general situation.
Where it is stored, it is determined by the first weight. It is a place where things are dry, clear and clear. Nitrate is easy to be damp, and the moisture is easily soluble, resulting in a certain amount. If it is placed in a tidal place, it is not easy to be damaged, and it may be biochemically reversed, and its effectiveness is improved. Good pass, can avoid accumulation and avoid the risk of danger. It can be controlled and prevented from being caused by high temperature.
Furthermore, the containers that are stored cannot be ignored. It is advisable to use dense devices, such as plastic barrels and barrels, to prevent external factors from invading. The barrel body is in good condition, cracking and holes, so as to prevent the leakage of nitrate. And the equipment is compatible with nitrate, and it is not necessary to cause and reverse the process.
It is necessary to fix it properly. Because of the solid material, if it is not fixed on the way, it will shake or collide, or cause the container to break, and the nitrate will be scattered. The road is bumpy and urgent, which may cause the unfixed object to shift and fall.
In addition, the environment is also important. Avoid high and tidal environments. In summer, if it is exposed to the hot sun, the temperature will rise, and the shadow will be nitrate-prone. In case of rain, it should be protected from rain, and a tarp can be covered.
People also know about it. Familiar with the characteristics of nitrate, in case of sudden damage, such as container breakage or leakage, it can be properly handled and operated in a safe manner to ensure the safety of the product. In this way, the storage of nitrate in 3-5 grooves can be comprehensive, less loss, and avoid safety hazards.