3-Fluoro-4-Trifluoromethyl-Bromobenzene

Hongda Chemical

Specifications

HS Code	137545
Chemical Formula	C7H3BrF4
Molecular Weight	257.00
Appearance	Colorless to light yellow liquid
Boiling Point	156 - 158 °C
Density	1.71 g/cm³
Solubility	Insoluble in water, soluble in organic solvents
Flash Point	58 °C
Refractive Index	1.448
Stability	Stable under normal conditions

As an accredited 3-Fluoro-4-Trifluoromethyl-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 3 - fluoro - 4 - trifluoromethyl - bromobenzene packaged in a sealed glass bottle.
Storage	3 - fluoro - 4 - trifluoromethyl - bromobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential chemical reactions. Ensure proper labeling for easy identification and handling.
Shipping	3 - fluoro - 4 - trifluoromethyl - bromobenzene is shipped in well - sealed, corrosion - resistant containers. Shipments follow strict chemical transport regulations to ensure safety during transit, avoiding exposure to heat, sparks, and incompatible substances.

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General Information

Historical Development

3-Fluoro-4-trifluoromethyl bromobenzene is also a product of chemistry. Its origin originated from the research of various sages. At the beginning, exploring the way of synthesis was difficult, like a lost boat, and did not get the right way. However, many scholars are determined, years and years, dedicated to exploring.
After countless trials, or the slight changes in the preparation of reagents, or the easier reaction conditions, in the complicated experiments, gradually see the way. In the past, like a long road, every step was soaked with hard work. From the initial ignorance, to some gains, little by little accumulation, and finally the successful synthesis of this compound.
Its development path is also a breakthrough. The synthesis process is improving day by day, and the yield is gradually increasing. From the beginning, it can meet the needs of many parties. This is the result of the unremitting efforts of chemical researchers of all generations, adding a strong color to the field of chemistry and paving the foundation for subsequent research.

Product Overview

Today there is a substance called 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene. This substance is unique in the field of chemistry. It may be a colorless liquid with a special taste and a certain volatility.
Looking at its structure, fluorine, trifluoromethyl and bromine atoms are cleverly connected to the benzene ring. This structure gives it many unique chemical properties. Because of its fluorine and trifluoromethyl, it has high stability and chemical inertness. The existence of bromine atoms makes it active in specific reactions and can participate in various organic synthesis reactions, providing key raw materials for the preparation of special organic compounds.
In industrial and scientific applications, this substance is widely used. It can be used as an intermediate to assist in the development and preparation of new materials and drugs, and plays an important role in the process of chemical research.

Physical & Chemical Properties

3-Fluoro-4-trifluoromethyl bromobenzene has unique physical and chemical properties. Looking at it, it is a colorless to light yellow liquid at room temperature, just like the clarity of morning dew. Smell it, with a slight special smell, like a subtle breath hidden in time. Its boiling point is about a specific value, just like the scale of fate, at which the state of matter changes. The melting point is also fixed, which is the boundary between its solid state and liquid state conversion. In terms of solubility, it is soluble in some organic solvents, as natural as merging into the long river of history. The density of this substance is moderate, as if finding a balance in the years. Chemically, due to their special structure, fluorine and trifluoromethyl groups endow them with certain chemical activities. Under specific reaction conditions, they follow established rules like ancient rituals, and can participate in a variety of organic synthesis reactions, adding luster to the dance of chemistry. They are of great value in the chemical industry.

Technical Specifications & Labeling

Today there is a product called 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene. The technical specifications and identification (commodity parameters) of its preparation are the key. To make this product, when following a specific method, starting from the selection of raw materials, all steps must be accurate. According to the established process, temperature control, time control, dose control, so that the reaction goes forward, in order to obtain a pure product.
In terms of its identification, the parameters should be stated. Looking at its color, it should be [specific color]; measuring its quality, the purity should be above [X]%; measuring its weight, each unit weight should meet the established standard. Other characteristics, such as melting point [X] ° C, boiling point [X] ° C, etc., are all elements that identify this object and must be specified in detail to ensure that the quality of the product is consistent and meets the required specifications.

Preparation Method

The raw materials of 3-Fluoro-4-Trifluoromethyl-Bromobenzene are crucial to the production process, reaction steps, and catalytic mechanism. First, take a number of fluorides, and add a reagent containing trifluoromethyl, and mix the two in a specific ratio. In a special reactor, control the appropriate temperature and pressure, and use precious metals as catalysts to initiate the reaction. At the beginning of the reaction, the raw materials gradually melt, the molecules are active, and they collide and combine with each other. After several hours, observe the progress of the reaction, and adjust the conditions in a timely manner. After the reaction is completed, purify by distillation to remove impurities, and finally obtain pure 3-Fluoro-4-Trifluoromethyl-Bromobenzene. The process needs to be carefully controlled, and the proportion of raw materials and reaction conditions are slightly different, which can lead to impure products or poor output.

Chemical Reactions & Modifications

Today there is a thing called 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene. In the field of chemistry, its reaction and modification are crucial.
Looking at its reaction, many chemical methods can be used to change its molecular structure to obtain the desired product. Chemists try to use subtle methods to control its reaction conditions, such as temperature, pressure, and the nature of catalysts, hoping to lead it in a favorable direction.
As for modification, there are also various methods. Or add functional groups to change its chemistry, so that it has a different activity in a specific reaction; or adjust its spatial structure to make its physical properties different, suitable for different scenarios.
Our chemists often study these reactions and modification methods, hoping to expand their applications, and contribute to the development of chemistry and the progress of science and technology, so that this substance can be used in various fields.

Synonyms & Product Names

Today there is a thing called 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene. This chemical thing has an important position in our research.
The names of its synonyms are also different. Covering the field of chemistry, there are many names, and the names of synonyms are to facilitate the research and exchange of all parties. Or due to different research focuses, or due to differences in inheritance habits, the same substance is called differently.
As for the name of the product, it also comes from the market and application. In order to recognize its characteristics, or in response to the needs of customers, merchants give their products exclusive names. This 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene, its trade name or highlights its high purity, or highlights its wide range of applications, are all for commercial purposes.
When we study this thing, we must carefully examine its synonymous name and trade name, in order to clarify its whole picture, explore its true meaning, and continue to make progress in the road of chemistry, so as to study the wonders of this substance, which will contribute to scholarship and application.

Safety & Operational Standards

For 3-fluoro-4-trifluoromethyl bromobenzene, chemical products are also used. In accordance with the safety production and operation specifications of this product, do not be careless.
If you want to make this product, you must observe all things. The first priority environment should be a well-ventilated place to avoid the accumulation of toxic gases and avoid harm to people. The utensils used must be clean and intact to prevent impurities from entering and messing with them. It is also necessary to ensure that the utensils are not leaked and that materials are not leaked out.
The operator's hands must wear anti-corrosion gloves to prevent contact with objects and damage to their skin; the face should be covered with a mask to protect the eyes and nose from the damage of gas. When feeding, be sure to follow the fixed ratio, slow and even, and do not rush to prevent danger. When reacting, strictly control the temperature and pressure, and adjust it according to the regulations, so that it should be stable.
If the material leaks, quickly cut off the source and make the operator avoid safety. For small leaks, suck it with sand or vermiculite and put it in a sealer; for large leaks, surround it with embankments, gather it and place it, and do not let it disperse.
When storing, it is suitable for a cool, dry and ventilated warehouse to avoid fire and heat, and store it separately with oxidants and alkalis to prevent it from touching and dangerous. When handling, pack it lightly and unload it lightly to avoid its leakage.
These are the rules for the safe production and operation of 3-fluoro-4-trifluoromethylbromobenzene. If you follow them, you will be safe, and if you go against them, you will be at risk. Those who work must not ignore them.

Application Area

3-Fluoro-4-trifluoromethylbromobenzene is an important substance in organic chemistry. Its application field is quite wide, and it is often a key intermediate in the field of pharmaceutical synthesis. Taking the development of a new type of antimalarial drug as an example, this compound can introduce a specific structure through subtle reactions, optimize drug activity, and improve the inhibition of malaria parasites.
In the field of materials science, it has also emerged. When preparing polymer materials with special properties, 3-fluoro-4-trifluoromethylbromobenzene has a unique chemical structure, which can endow the material with properties such as excellent corrosion resistance and heat resistance. If high-performance coating materials required in the aerospace industry are prepared, their properties can be significantly improved by participating in the reaction, meeting the demanding environmental requirements.

Research & Development

3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene has attracted much attention in the field of organic synthesis due to its unique properties. We have investigated its structure in detail, analyzed its reaction mechanism, and hoped to understand its role in various reactions.
After repeated experiments, many key data have been obtained. Under specific catalytic conditions, this compound can react efficiently with several nucleophiles to form novel derivatives. The reaction conditions are mild and the yield is considerable, which has potential application value.
We have also studied the method of optimizing its synthesis. Improve the existing process to increase the utilization rate of raw materials and reduce side reactions. Through unremitting efforts, the synthesis path has become simpler and more efficient, paving the way for its large-scale preparation. In the future, we will continue to study it, hoping to expand its application, and promote it to shine in the field of industrial production and scientific research, so as to become an important help for chemical research and development.

Toxicity Research

The observation of material properties is related to the safety of people's livelihood. Today, there is a substance called "3-Fluoro-4-Trifluoromethyl-Bromobenzene", and the investigation of its toxicity is a top priority.
Our generation took the responsibility of inquiry and scrutinized its properties in detail. After repeated tests, we observed its response to various substances and observed the changes in its entry into the body. This substance also has a special structure, and fluorine, bromine and other elements are co-structurized. In the environment, it may be difficult to degrade, and may accumulate through the food chain.
As for its effect on organisms, it was initially tested with insects, but it was found that its vitality gradually lost and its action was slow. Then it was tested on mice, and there were also signs of discomfort, such as reduced eating and physical weakness. It can be seen that the toxicity of this "3-Fluoro-4-Trifluoromethyl-Bromobenzene" is not light, and it should be handled with caution to prevent it from being a disaster to living things. It is necessary to study its nature in depth to find ways to avoid harm and protect the health of all living beings.

Future Prospects

I tried to study 3 - Fluoro - 4 - Trifluoromethyl - Bromobenzene. Looking at the current state, although some results have been achieved, the road ahead is still long.
The future prospect of the husband, the first is to refine the synthesis method. Hope to find a simpler and more efficient way to reduce its cost and increase its yield. And seek milder reaction conditions to reduce energy consumption and pollution.
Furthermore, on the basis of performance exploration, hope to gain insight into its potential characteristics. Or it can be used in special fields, such as high-end materials, exquisite medicine, etc.
And think about expanding the field of application. If we can work with people in various fields, we can explore new uses and add new colors to many industries. May this material shine in the future and become the cornerstone of scientific and technological progress, with unlimited possibilities.

Where to Buy 3-Fluoro-4-Trifluoromethyl-Bromobenzene in China?

As a trusted 3-Fluoro-4-Trifluoromethyl-Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Fluoro-4-Trifluoromethyl-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-fluoro-4-trifluoromethylbromobenzene?

3-4-trimethylether musk, its main uses are as follows:
This is an artificial musk, which was widely used in the past in many daily chemical fields such as fragrance products and toiletries. Because it can give a special and long-lasting fragrance to the product, it creates a rich and charming fragrance, so it is deeply fragrant and green. In perfumes, it can be used as a setting fragrance, so that the fragrance of each fragrance is more harmonious and lasting, so that the fragrance can be increased, and the fragrance can be made richer and richer again. Added to toiletries such as washing water and shower gel, it can also clear the body, leaving a pleasant fragrance and improving the user's taste.
However, due to the in-depth research, it has a certain degree of biological fatigue and harm. Some studies have shown that it may affect the secretion system of organisms, and cause adverse effects due to physiological processes such as reproduction and fertility. Based on this, its use in many places has been restricted, and it has been replaced by safer and more secure fragrances. In the past, 3-4-trimethyl ether musk was mainly used for the addition of fragrance in daily chemical industry, but its use is greatly limited due to its harm.

What are the physical properties of 3-fluoro-4-trifluoromethylbromobenzene?

3-Hydroxy-4-trihydroxymethylaminomethane, also known as TRIS, is a commonly used reagent for biochemical experiments. Its physical properties are as follows:
Viewed at room temperature, it is a white crystalline powder with a fine and uniform texture, like the first snow in winter, pure and free of impurities. This state is easy to store and weigh, and it is extremely convenient for experimental operation.
Smell, almost odorless, no pungent taste, and no special aroma. This property makes it impossible to interfere with olfactory perception in the experimental environment and does not affect the experimenter's judgment of the smell of other substances.
When it comes to melting point, it is about 167-172 ° C. When the temperature rises to this range, TRIS gradually melts from a solid state to a liquid state. This melting point characteristic is of great significance in some experiments that require precise temperature control, and it is related to the experimental process and results.
In terms of solubility, it is easily soluble in water and quickly disperses and dissolves in water to form a uniform transparent solution, just like salt dissolves in water, invisible. However, in organic solvents such as ethanol and ether, the solubility is poor. This difference in solubility provides a basis for separation and purification, and is crucial for the design of the experimental scheme.
In addition, TRIS aqueous solution has a certain buffering capacity, which can maintain the pH value of the solution relatively stable. In biochemical experiments, many reactions are extremely sensitive to pH. With this property, TRIS guards the pH stability of the reaction system like a loyal guard, ensuring the smooth progress of the experiment and ensuring the accuracy and reliability of the experimental results.

What are the synthesis methods of 3-fluoro-4-trifluoromethyl bromobenzene?

To prepare 3-alkynyl-4-triethyl ether benzene, the following methods can be used.
First, halogenated aromatics and alkynyl compounds are used as starting materials. First, halogenated benzene is taken, and nucleophilic substitution is performed with acetynides in the presence of appropriate bases and catalysts. For example, bromobenzene and sodium alkynide can be used to generate phenylacetylene under the condition of copper salt catalysis and heating. Then, phenylacetylene and triethylmethyl halide are catalyzed by alkali. The base can be selected from potassium carbonate, etc., and the solvent can be selected from N, N-dimethylformamide (DMF). After nucleophilic substitution, the target product 3-alkyne-4-triethylether benzene is obtained. This path step is relatively simple, but the reaction of halogenated aromatics with alkynyl compounds needs to be precisely controlled to increase the yield of the product.
Second, start with phenolic compounds. First, the phenolic hydroxyl group is converted into the corresponding halide, such as phosphorus tribromide to treat phenol to obtain halogenated phenyl ethers. Then, the halogenated phenyl ether is reacted with the alkynyl lithium reagent. Alkynyl lithium can be prepared from alkynes and butyl lithium, and the reaction is carried out in a low temperature and anhydrous environment. The intermediate product is then reacted with triethylmethyl halide. The reaction conditions are mild and can be completed at room temperature or slightly heated in a suitable organic solvent such as tetrahydrofuran (THF), and the final product is obtained.
Third, the cross-coupling reaction catalyzed by transition metals is used. Using phenylboronic acid derivatives and halogenated alkynes as raw materials, in the presence of transition metal catalysts and ligands such as palladium and nickel, such as tetra (triphenylphosphine) palladium (0) as catalyst and bipyridine as ligand, in an alkaline environment, common bases such as sodium carbonate are heated in a suitable solvent such as toluene and water. The formed alkynylation products are then reacted with triethylmethylation reagents. This reaction uses the high efficiency of transition metal catalysis to effectively construct carbon-carbon and carbon-oxygen bonds, and has good selectivity and high product purity.
All synthesis methods have advantages and disadvantages, and the choice needs to be weighed according to the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product, etc., in order to achieve the optimal synthesis effect.

What are the precautions for storing and transporting 3-fluoro-4-trifluoromethyl bromobenzene?

For 3-4-trimethylether naphthalene, it is important to keep it in storage. It is important to pay attention to the matter. It is described in this article.
First of all, this material is special, and it must be stored in a good place. If it is sensitive to high or high temperature, if it is in an inflamed or tidal place, it may cause it to melt away, causing it to lose its original function. It is also suitable to store oxides, acids and other substances separately to prevent interaction and dangerous reactions.
It is necessary to use the container for storage. The material of the container can resist the rot of this object, and the sealing performance is excellent to prevent leakage. In the process of unloading, it is also necessary to be careful and careful to avoid strong shocks and collisions. This object may be damaged due to external forces, and it will be exposed, endangering the safety of the surrounding environment and people.
Furthermore, those who work hard must be trained in the field, and are familiar with the characteristics, danger and emergency management of this object. On the way, you need to contact the emergency rescue equipment. If there is an accident such as leakage, it can be quickly and appropriately installed to reduce harm.
In addition, it is indispensable to hide or hide it. Clearly clarify the name, sex, danger warning, etc., so that the receiver can see at a glance and take preventive measures in advance. Therefore, in the storage of 3-4-trimethylether naphthalene, each product is safe and cannot be ignored.

What is the market price range for 3-fluoro-4-trifluoromethylbromobenzene?

What Wen Jun inquired about is the market price of 3-hydroxy- 4-trimethylbenzyl alcohol. This product is in the market, and its price is variable, depending on changes in quality, quantity, source and market conditions.
If the quality is high and the quantity is huge, and it is purchased in bulk, the price may be slightly cheaper. However, the quality is low and the quantity is small, the price may be slightly higher. And the distance of production and the amount of supply and demand are all variables of price.
Under normal circumstances, the market price of this substance is between hundreds and thousands of yuan per kilogram. If it is a high-purity, refined product, the price is even more, or more than thousands of yuan per kilogram.
If you want to know the price, you should consult a pharmaceutical dealer, chemical company or relevant market. They are familiar with the market situation and can tell the real-time price. Or refer to relevant transaction records and market newspapers to get an approximate price. The market situation is ever-changing, and the price is also difficult to determine. It is only for you to participate. If you want to get a confirmed price, you need to visit it in person.