3-Fluoro-4-Nitrobenzenecarboxylic Acid

Hongda Chemical

Specifications

HS Code	705738
Name	3-Fluoro-4-Nitrobenzenecarboxylic Acid
Chemical Formula	C7H4FNO4
Molar Mass	185.11 g/mol
Appearance	Solid (usually white to off - white)
Melting Point	178 - 182 °C
Solubility In Water	Poorly soluble
Solubility In Organic Solvents	Soluble in some polar organic solvents like DMSO, DMF
Pka	Around 2.4 (approximate value for the carboxylic acid group)
Odor	Odorless or very faint odor

As an accredited 3-Fluoro-4-Nitrobenzenecarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 3 - fluoro - 4 - nitrobenzenecarboxylic acid packaged in a sealed plastic bag.
Storage	3 - Fluoro - 4 - nitrobenzenecarboxylic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. Due to its chemical nature, it should be separated from incompatible substances to avoid any hazardous interactions.
Shipping	3 - Fluoro - 4 - nitrobenzenecarboxylic acid is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper handling, storage, and transportation to prevent leakage and environmental risks.

Free Quote

Competitive 3-Fluoro-4-Nitrobenzenecarboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

General Information

Historical Development

3-Fluoro-4-nitrobenzoic acid is also a product of chemistry. Although its origin is difficult to study in detail, the evolution of chemical techniques has led to the gradual study of this substance by various families. In the past, chemical sages studied the physical properties and explored the methods of synthesis, with the aim of making progress.
At the beginning, the road to synthesis was full of thorns, and all kinds of attempts failed to achieve good results. However, chemists were determined to experiment repeatedly, or change the raw materials, or easy conditions. After a long period of research, a method was obtained, which gradually enabled the preparation of 3-fluoro-4-nitrobenzoic acid.
Later, its application field also gradually widened. The development of this chemical product depends on the wisdom and perseverance of chemists of all dynasties. It starts from the end and eventually becomes a useful material, adding a bright pearl to the road of science.

Product Overview

3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid, it is also a chemical material. Its properties are special and special. This compound is exquisite, and the fluorine atom and the nitro-phenylcarboxylic acid group are cleverly phase.
Its fluorine, with its special chemical properties, can be reversed and changed. The existence of nitro groups also adds its activity, or involves nuclear substitution, or the original phase. The base of phenylcarboxylic acid, in the synthesis of phenylcarboxylic acid, is one of the key angles, and can lead to functional compounds, forming multiple compounds.
This object may be used to study materials, to study their characteristics, and to cure diseases; or it may involve materials science, to help create new materials, with special properties, such as energy and light energy. It is one of the first in the field of transformation, which can be used to synthesize new paths, explore unknown realms, promote transformation, and conduct more research.

Physical & Chemical Properties

3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid, it is also a matter of transformation. Its physical reason is often high, and it is solid and crystalline, and the earth is dense. Melting is special, and at a certain fixed degree, it melts when encountered. This degree is the property of its matter.
Its chemical properties, carboxyl group activity, can be used to neutralize and reverse, generating phase. Nitro properties are also low, and it is oxidizing. The existence of fluorine atoms, and its specific activity, can be used under specific conditions, and the generation and substitution of other substances, etc., show the enrichment of the line, and the synthesis field of chemical research has a value.

Technical Specifications & Labeling

3-Fluoro-4-nitrobenzoic acid is an important product in chemical preparation. Its process specifications and identification (product parameters) are related to the quality and application.
To make this product, the raw materials must be pure, and the ratio should be fine. Such as fluoride, nitro compounds and carboxylic acid raw materials, when mixing, the temperature and humidity are fixed. The reaction time also needs to be precisely controlled. If it is too long, the by-product will increase, and if it is short, the reaction will not be complete.
In terms of identification, the appearance should be white or off-white powder with uniform particle size. The purity must be extremely high, and the impurity content is minimal. Parameters such as melting point and boiling point should conform to the established specifications. In this way, we can ensure that this product can be used in various fields such as medicine and chemical industry to achieve its due effect, and lay a solid foundation for various applications.

Preparation Method

3-Fluoro - 4 - Nitrobenzenecarboxylic Acid is an important chemical synthesis product. The preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism.
To make this product, the first raw material is selected. When the fluorine-containing, nitro-and benzene-ring compounds are used as the starting materials, this is the basis for laying the structure of the product. In the production process, multiple fine reactions are required. First, fluorine atoms are introduced into the benzene ring at the appropriate position in a specific reaction. This step requires precise control of the reaction conditions, such as temperature, catalyst type and dosage.
In the reaction step, the introduction of nitro groups is also crucial. It is often achieved by nitrification to control the reaction process and product selectivity and prevent excessive side reactions. In terms of catalytic mechanism, the use of high-efficiency catalysts can accelerate the reaction rate and increase the yield. Or use metal catalysts to promote the reaction with its unique electronic structure, and optimize the reaction system to ensure a good connection between the steps, so as to efficiently prepare 3-Fluoro-4-Nitrobenzenecarboxylic Acid.

Chemical Reactions & Modifications

Recently researched 3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid, the study of the modification of this product, its transformation and reverse engineering, and the heart force. The transformation and reverse engineering are like sailing against the current, and they will not retreat. If you want to get its delicacy, you must observe all kinds of products.

>

>
< r > >

>

Refinement, the control of the degree of improvement, the good quality of fine-selected catalysis, and the good condition of the reverse. The rate of the quality of the material can be improved. This process has made me well aware of the reversal of the process, and the way of modification, the process of the cloth, and the research with heart, will be able to be used for a long time, and there will be a lot of improvement.

Synonyms & Product Names

3-Fluoro-4-nitrobenzoic acid, this substance is quite useful in the field of chemistry. Its synonymous name is also known. Or "3-fluoro-4-nitrobenzene carboxylic acid", both refer to the same thing.
From the perspective of this chemical, it is an important material in the process of scientific research. It can be used in various organic synthesis experiments and is a key raw material for the preparation of other types of compounds. Its characteristics determine its use, and it is indispensable in the field of organic chemistry.
Although its names are different, it refers to the only one. When researchers study and operate, they need to clarify the names of all synonyms in order to avoid confusion and ensure that the experiments are correct and the research is smooth. No matter what it is called, its essential characteristics are constant and contribute significantly to the research and development of chemistry.

Safety & Operational Standards

3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid is an important chemical product. It is crucial to its safety and operating standards and should not be ignored.
This product is dangerous and is related to safety. Store first. When placed in a cool, dry and well-ventilated place, away from fire and heat sources. If it is heated or triggers a chemical reaction, accidents may occur. And it needs to be stored in isolation from oxidizing agents, reducing agents, etc., to prevent interaction and unexpected changes.
In terms of operating standards, operators must wear appropriate protective equipment. For example, wear protective glasses to protect your eyes from possible splashes; wear protective gloves to prevent skin contact. When operating, it is advisable to carry out it in a fume hood to ensure air circulation and avoid the accumulation of harmful gases, which endangers people.
During use, the amount of use needs to be precisely controlled and cannot be increased or decreased at will. The operation steps should be strictly in accordance with the established procedures and must not be changed without authorization. If the operation is wrong, or the product is impure, or it may cause a safety accident.
Once a leak occurs, do not panic. In the event of a small leak, it should be quickly covered and absorbed with inert materials such as sand and dry lime, and then properly disposed of. A large leak requires immediate evacuation of personnel, emergency response, and disposal by professionals.
Only by strictly adhering to safety and operating standards can we ensure the safety of 3-Fluoro-4-Nitrobenzenecarboxylic Acid related operations, avoid accidents, and ensure the safety of people and the environment.

Application Area

3-Fluoro-4-nitrobenzoic acid is also a genus of chemical substances. Its application field is quite involved. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. The characteristics of fluorine, nitro and carboxyl groups in the structure can endow the prepared drugs with unique activities, or enhance their affinity to specific targets, or optimize pharmacokinetic properties.
In the field of materials science, it also has potential uses. It can be chemically modified to introduce polymer systems to improve the properties of materials, such as enhancing their stability and adjusting their optical properties.
In organic synthetic chemistry, it is often used as a building block for building complex organic molecules. Due to its unique functional groups, it can skillfully combine with other compounds through a variety of reaction paths, expanding the possibility of organic synthesis and providing a key foundation for the creation of novel organic compounds.

Research & Development

In modern times, chemistry has flourished, and the research of various compounds has become more and more refined. Today, there is 3-Fluoro-4-Nitrobenzenecarboxylic Acid, and our generation deeply believes that the research is important.
At first, explore its properties, observe its physical characteristics in detail, such as color, state, and taste, measure its degree of melting and boiling, and know its solubility, so as to clarify its basic properties. Repeat its chemical properties, observe its response to various substances, or encounter acid-base, or redox agents, and record its changes in detail to explain the rules of the reaction.
Then, think about its preparation method. Search for ancient and modern techniques, or improve the old method, or create new rules, and strive to obtain pure products in a simple and efficient way.
As for the field of application, it is also widely explored. Or used in medicine, hoping to help cure diseases; or applied to materials, hoping to add new quality ability.
We should study diligently, and expect that the research and development of 3-Fluoro-4-Nitrobenzenecarboxylic Acid will have outstanding achievements to benefit the world.

Toxicity Research

The study of poisons in the world is related to the health of people's livelihood and must not be ignored. Today there is a thing called "3-Fluoro-4-Nitrobenzenecarboxylic Acid", which is quite important in the study of toxicity.
The toxicity of this thing needs to be investigated in detail. Or observe its response to biological organisms, observe the changes of cells and the differences in physiology. After various experiments, we can know its impact on living beings. Or touch the skin and feel its irritation; or enter the body and observe the state of the viscera.
Study its toxicity, and also understand the path of its transmission and the method of digestion. Explore how it circulates in the natural environment, and what harm it has on water, soil and living beings. It is even more necessary to investigate how to reduce its poison and ensure the peace of all things. In this way, we can gain insight into the nature of this thing, so as to protect all living beings from danger and maintain the tranquility of the world.

Future Prospects

Fu 3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid, it is also a thing of transformation. I have been researching this for years, and my heart is full of excitement every time I think about the prospect of the future.
The properties of this compound are special, and it is a field of application. It may not be possible to develop its research skills in the future, and help those who make special effects. It is a common disease and solves the suffering of patients. Or in the context of material science, its characteristics, and new materials, used in aerospace, aerospace, and other fields, to promote its progress.
Our researchers are diligent and unremitting in research. We hope to explore the secrets of this compound in depth and explore its energy, so that it can be used by the world and benefit people. I believe that with the joint efforts of my colleagues, 3 - Fluoro - 4 - Nitrobenzenecarboxylic Acid will be able to make great progress in the future.

Where to Buy 3-Fluoro-4-Nitrobenzenecarboxylic Acid in China?

As a trusted 3-Fluoro-4-Nitrobenzenecarboxylic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Fluoro-4-Nitrobenzenecarboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Fluoro-4-Nitrobenzenecarboxylic Acid?

3-Fluoro-4-nitrobenzoic acid has a wide range of uses. In the field of medicinal chemistry, it is often a key synthetic raw material. Many drug molecules with specific physiological activities need to be used as starting materials in the construction process. With its unique chemical structure, specific functional groups can be precisely introduced through a series of reactions, so as to obtain compounds with specific pharmacological effects for the treatment and research of diseases.
In the field of materials science, it also has important functions. It can participate in the preparation of special polymer materials and give the material unique properties by polymerizing with other monomers. For example, to improve the heat resistance, mechanical properties or optical properties of the material, it is widely used in electronics, aerospace and other fields that require strict material properties.
Furthermore, in organic synthesis chemistry, it is a very commonly used intermediate. Because of its fluorine atoms, nitro groups and carboxyl groups, they are all active reaction check points, and can be derived through various organic reactions, such as nucleophilic substitution, reduction, esterification, etc., many organic compounds with different structures, which greatly enrich the types and quantities of organic compounds and provide a rich material basis for the development of organic synthesis chemistry.

What are the physical properties of 3-Fluoro-4-Nitrobenzenecarboxylic Acid?

3-Fluoro-4-nitrobenzoic acid is a kind of organic compound. It has unique physical properties, which are described in detail by you.
Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This color state is easy to identify with the naked eye. In many chemical experiments and industrial production scenarios, it is one of the important characteristics to identify this substance.
When it comes to the melting point, it is between 182-186 ° C. The melting point is an important physical constant of a substance and is of great significance in the identification and purification of this compound. With this characteristic, the purity can be determined by melting point measurement experiments. If the measured melting point is consistent with the standard value and the melting range is narrow, it indicates that the purity of the compound is quite high; conversely, if the melting range is too wide or the melting point deviates from the standard value, it may contain impurities.
Its solubility is also a key physical property. This compound is slightly soluble in water, because its molecular structure contains functional groups such as fluorine atoms, nitro groups and carboxyl groups, resulting in weak interaction with water molecules, making it difficult to dissolve in polar aqueous phases. However, it has good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc. This property lays the foundation for its application in the field of organic synthesis, and many reactions can be carried out with suitable organic solvents as the reaction medium.
In addition, the physical properties of 3-fluoro-4-nitrobenzoic acid, such as density and vapor pressure, also vary with temperature, pressure and other conditions. However, due to limited data, exact values cannot be described in detail. However, in practical operation and application, such properties have a significant impact on the control of reaction conditions, material separation and storage.
In summary, the physical properties of 3-fluoro-4-nitrobenzoic acid are indispensable basic information for chemical research, chemical production and related fields, and are of great significance for in-depth understanding of the characteristics and rational application of this compound.

What are the synthetic methods of 3-Fluoro-4-Nitrobenzenecarboxylic Acid?

The synthesis method of 3-fluoro-4-nitrobenzoic acid has been explored by many researchers throughout the ages. One of the common methods is to use 3-fluorobenzoic acid as the starting material. Shilling 3-fluorobenzoic acid is co-heated with mixed acids (sulfuric acid and nitric acid) to carry out nitrification reaction. Among them, sulfuric acid has a catalytic effect, which prompts the decomposition of nitric acid to produce nitroyl positive ions, which attack the benzene ring of 3-fluorobenzoic acid. Due to the fact that the fluorine atom is an ortho-para-localized group and the space steric resistance and other factors, the nitro group is mostly introduced into the para-site of the fluorine atom, and then 3-fluoro-4-nitrobenzoic acid is obtained. After the reaction, the product is purified through various operations such as neutralization
Furthermore, 4-nitroaniline can also be used as a starting material. First, 4-nitroaniline is diazotized, treated with sodium nitrite and hydrochloric acid to obtain diazonium salts. Then, fluoroborate acid is added to form fluoroborate, which is decomposed by heating, and fluorine atoms replace diazo groups to obtain 4-fluoronitrobenzene. Then, 4-fluoronitrobenzene is used as a substrate and carboxylated with carbon dioxide under a suitable catalyst and pressure to obtain 3-fluoro-4-nitrobenzoic acid. This route step is slightly complicated, but the selectivity is quite high.
In addition, halogenated aromatics are used as raw materials, and suitable halogenated aromatics are selected. Through a metal-catalyzed coupling reaction, fluorine atoms are first introduced, and then nitrification, carboxylation and other series of reactions are used to gradually construct the target molecule. This synthesis path requires precise control of the reaction conditions, and the choice of catalyst is also crucial, which is related to the success or failure of the reaction and the yield.
The above methods have their own advantages and disadvantages. The choice needs to be weighed according to actual needs, raw material availability, cost and many other factors in order to find the best synthesis method.

3-Fluoro-4-Nitrobenzenecarboxylic precautions when storing Acid

3-Fluoro-4-nitrobenzoic acid, this is a chemical substance. When storing it, pay attention to many matters.
The first thing to bear the brunt is the temperature and humidity of the environment. This substance should be stored in a cool and dry place. If it is exposed to high temperature, it may cause its chemical properties to change, accelerate decomposition or cause other chemical reactions. If the humidity is too high, water vapor may interact with the substance, causing its purity to be damaged, or even appear deliquescent.
Furthermore, it must be concerned about its isolation from other substances. 3-Fluoro-4-nitrobenzoic acid has a certain chemical activity and should be kept away from strong oxidants, strong bases and other substances. Strong oxidants meet with it, or cause severe oxidation reactions, causing danger; strong alkalis and the like can also trigger chemical reactions, affecting its quality and stability.
Repeat, storage containers are also crucial. When choosing a suitable material container, such as a corrosion-resistant glass bottle or a specific plastic container. The glass material is stable and difficult to react with the substance; some special plastic containers can also effectively resist its corrosion and ensure the safe storage of the substance.
And the storage place should be well ventilated. If the ventilation is not smooth, once the substance evaporates a little gas, it may also affect the air quality of the surrounding environment after accumulation or cause safety hazards.
In addition, the storage area should be clearly marked, indicating the name, characteristics and precautions of the substance. This allows the staff to identify and operate, avoid accidental touch and misuse, and prevent accidents.
In short, proper storage of 3-fluoro-4-nitrobenzoic acid is related to its quality and safety, and is of great significance for use and subsequent treatment. It must not be taken lightly.

3-Fluoro-4-Nitrobenzenecarboxylic the market price of Acid

The market price of 3-fluoro-4-nitrobenzoic acid often fluctuates due to many factors. Looking at the price of chemical raw materials in the past, the supply and demand situation is one of the keys. If the demand for this acid is strong, such as the use of medicine, pesticides or special material synthesis is greatly increased, but the supply is limited. For example, if the manufacturer reduces production for some reason, or the raw material is difficult to obtain, the price will increase.
Furthermore, the production cost also affects its price. If the price of raw materials fluctuates, such as fluoride and nitro compounds required for the preparation of this acid, the cost will rise, and the manufacturer will raise the price in order to ensure profits. And the complexity of the production process, the amount of energy consumption, etc., are all related to the cost, which in turn affects the market price.
Regional differences cannot be ignored. In different places, transportation costs and tax policies vary. In places with convenient transportation and concentrated industries, transportation costs are low, market competition is fierce, and prices may be relatively stable; in remote areas, transportation is inconvenient, taxes and fees are different, and prices may be high.
From the perspective of historical conditions, the chemical market is changing, and the price of this acid may fluctuate sharply. The economic situation is improving, and various industries are booming, driving prices up; in the economic downturn, demand is shrinking, and prices may be under pressure.
Overall, in order to know the exact market price of 3-fluoro-4-nitrobenzoic acid, it is necessary to gain real-time insight into market supply and demand, cost changes, regional factors, etc., and pay close attention to industry trends in order to accurately grasp its price trend.