Hongda Chemical
Products
Home  /  Products  / 

3-Fluoro-4-Methoxybenzeneboronic Acid

3-Fluoro-4-Methoxybenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

188712

Name 3-Fluoro-4-Methoxybenzeneboronic Acid
Molecular Formula C7H8BO4F
Molecular Weight 185.95
Appearance Solid (Typical)
Melting Point 155 - 159 °C
Boiling Point N/A
Density N/A
Solubility In Water Slightly soluble
Purity Typically high purity, e.g., 97%+
Cas Number 1256354-86-3

As an accredited 3-Fluoro-4-Methoxybenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluoro - 4 - methoxybenzeneboronic acid packaged in a sealed plastic bottle.
Storage 3 - fluoro - 4 - methoxybenzeneboronic acid should be stored in a cool, dry place. Keep it in a well - sealed container to prevent moisture absorption and contact with air, as boronic acids can be sensitive to oxidation. Store away from heat sources and incompatible substances like strong acids and bases. Ideal storage temperature is around 2 - 8 °C in a refrigerator if long - term storage is required.
Shipping 3 - Fluoro - 4 - methoxybenzeneboronic acid is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations. Shipment often involves temperature - controlled options to ensure stability during transit.
Free Quote

Competitive 3-Fluoro-4-Methoxybenzeneboronic Acid prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

3-Fluoro-4-Methoxybenzeneboronic Acid 3-Fluoro-4-Methoxybenzeneboronic Acid
General Information
Historical Development
3-Fluoro-4-methoxyphenylboronic acid is also a product of chemistry. It originated from the research of the past sages. At the beginning, many scholars explored the properties of substances and the laws of reaction in the field of chemistry. At that time, the understanding of this compound was still shallow.
After the years passed, everyone refined their skills and improved their procedures. After countless trials and errors, they gradually understood the way of its synthesis. From the crude attempt at the beginning to the exquisite maturity of the technique, the hardships during this period can not be expressed in a word.
Every step of evolution depends on the painstaking efforts of the ancestors, and with wisdom and sweat, to expand the boundaries of material cognition. 3-Fluoro-4-methoxyphenylboronic acid has been a commonly used product in chemical research since it was unknown. It has been used in chemical, pharmaceutical and other fields to develop its effectiveness and become an important stroke in the long volume of chemical development.
Product Overview
Description of 3-fluoro-4-methoxyphenylboronic acid
3-fluoro-4-methoxyphenylboronic acid, its color is pure and uniform, in the state of fine powder, white like snow, without variegated mottles. Looking at its crystal shape, it is regular and orderly, showing the delicate structure.
This product has unique chemical properties. Boron atoms are cleverly connected to phenyl rings, and fluorine and methoxy groups each occupy a specific position, giving it a different activity. In the field of organic synthesis, it is a key reagent. It can participate in many coupling reactions, such as the Suzuki-Miyaura reaction, forming carbon-carbon bonds, which is like building a delicate chemical building, paving the way for the creation of complex organic molecules.
Its stability is also good, and it can be stored for a long time in a moderate environment at room temperature without loss of performance. When encountering strong acids and alkalis, when careful, the structure may be damaged and the activity will be lost. When preparing, it is necessary to precisely control the conditions, the ratio of raw materials, temperature and heat are all key. After many trials, this high-quality 3-fluoro-4-methoxyphenylboronic acid has been obtained, which is a weapon for chemical research and industrial production.
Physical & Chemical Properties
3-Fluoro-4-methoxyphenylboronic acid, the physical and chemical properties of this substance are relevant to our research. Its color is pure and pure, often in a white crystalline state, like the condensation of frost and snow. Its melting point is quite high, about a certain degree, as if it adheres to its own characteristics. In organic solvents, it has a certain solubility, such as in alcohols and ether solvents, it can gradually melt and disperse, showing its compatibility with solvents. Its chemical activity is also considerable, and it is often a key player in many organic synthesis reactions. It can be cleverly combined with other substances to build new chemical structures. Such physical and chemical properties make it a shining star in the field of organic synthesis, which is cherished by many researchers and helps to explore the wonderful world of organic chemistry.
Technical Specifications & Labeling
Technical Specification and Identification of 3-Fluoro-4-methoxyphenylboronic Acid (Product Parameters)
Fu3-Fluoro-4-methoxyphenylboronic Acid, a key reagent for organic synthesis. Its technical specification, the first purity. When preparing, multiple refining processes are required to achieve high purity standards, and the impurity content must be strictly controlled in a very low range.
Furthermore, regarding its physical properties, the appearance should be white to off-white crystalline powder with uniform color and no visible foreign matter. Melting point is also an important parameter and should be in a specific range to ensure stable product quality.
In terms of identification, the name "3-Fluoro-4-methoxyphenylboronic acid" must be clearly marked on the product packaging, and the basic information such as chemical formula and molecular weight should be detailed. And key product parameters such as purity and water content should be indicated so that users can understand its quality characteristics and be accurately applied in scientific research and production.
Preparation Method
The preparation method of 3-fluoro-4-methoxyphenylboronic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is crucial, and suitable starting materials are required, such as specific halogenated aromatics and boron-containing reagents. The production process needs to be precisely controlled, from the setting of reaction conditions, such as temperature, pressure and reaction time, to the creation of the reaction environment, all of which need to be carefully controlled.
The reaction steps are advanced in sequence. First, the starting materials interact under specific conditions, initiate a chemical reaction, and go through an intermediate state to gradually convert into the target product. In this process, the degree and rate of reaction at each step affect the purity and yield of the final product. The catalytic mechanism of
cannot be ignored either. The selection of suitable catalysts can significantly improve the reaction efficiency and reduce the severity of the reaction conditions. High-efficiency catalysts can accurately guide the reaction direction, promote the reaction in the direction of generating the target product, and inhibit the occurrence of side reactions to ensure the quality of the product. Through careful regulation of the above elements, it is expected to achieve high-quality and efficient preparation of 3-fluoro-4-methoxyphenylboronic acid.
Chemical Reactions & Modifications
Recently, I have been researching the reaction and modification of 3-fluoro-4-methoxyphenylboronic acid, and I have some experience, and I am especially interested in it.
This compound has a wonderful way of reversing it. In the usual method, the combination of the two phases, or the formation of a new one, but there are also many constraints. The reversal of the parts, the degree of dissolution, and the quality of the solution all need to be carefully controlled. There is a slight difference, and the fruit is not easy.
It is not easy to seek its modification to make the performance better. Thinking about the ancient method, or starting with the transformation of the function, I hope to make a breakthrough. With different properties, according to the specific order, the effect of the reaction, and the reaction of the reaction, observe the physical properties of its generation.
Many times, we have gained something. By changing the reverse environment and adjusting the proportion, we can actually make this compound have different properties. Its activity is reduced, or it is more conducive to the synthesis of. This is the way to research and develop chemistry, and we can get one by one. We hope to provide one or two ideas to those who are good at it, and explore the subtleties of chemistry together.
Synonyms & Product Names
Today there is a product called 3 - Fluoro - 4 - Methoxybenzeneboronic Acid. This product has a wide range of uses in the field of chemistry. Or in organic synthesis, it is a key raw material; or in the process of pharmaceutical research and development, it is an important intermediate.
There are also various synonyms, each from its source, each referring to its own. However, they are all inseparable from the essence of this chemical substance. The name is the name given by the merchant to recognize its characteristics and facilitate its sale.
In the course of my chemical research, I often encounter such a situation of more than one thing. The reason is that the research angle and application scenarios are different, so the names are different. However, although the name is different, it is actually the same substance. Knowing this, in the study of chemistry, everything can be accurate and not confused.
Safety & Operational Standards
3 - Fluoro - 4 - Methoxybenzeneboronic Acid Safety Production and Operation Specifications
#1. Introduction
On 3 - Fluoro - 4 - Methoxybenzeneboronic Acid This product is related to safety production and operation specifications, and is the gist of the chemical industry. It should not be careless.
#2. Storage Regulations
This compound should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Its storage container must be tightly sealed to avoid excessive contact with air and moisture. Because it may react with moisture and oxygen, it will damage its quality and cause safety hazards. The storage area should be prepared with suitable materials to contain leaks to prevent environmental pollution and safety risks caused by leaks.
#3. Proper operation
The operator must have professional training and be familiar with the operating procedures. When operating, use appropriate protective equipment, such as protective clothing, gloves and goggles, to avoid contact with the skin and eyes. The operation site needs to be well ventilated. If it is operated in a fume hood, ensure its normal operation and remove volatile harmful gases in time. When using this object, the action should be slow and stable, and the measurement should be accurate. Do not let it fall off. Stir and other operations, the speed is appropriate, so as not to lose control of the reaction due to violent operation.
#4. Emergency treatment
If it comes into contact with the skin accidentally, rinse it with a large amount of flowing water immediately, and then wash it with soap. If it enters the eyes, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline, and then seek medical attention. In case of leakage, quickly evacuate unrelated personnel to a safe area and prohibit fire sources. Emergency personnel wear protective equipment, according to the amount of leakage, or absorb with inert materials such as sand and vermiculite, or neutralize with suitable chemical reagents, collect waste to the designated place for proper disposal.
#5. Conclusion
3 - Fluoro - 4 - Methoxybenzeneboronic Acid's safe production and operation specifications are essential for chemical practitioners. Only by following this specification can we ensure production safety, protect the health of personnel, and avoid environmental harm.
Application Area
3-Fluoro-4-methoxyphenylboronic acid is also an organic reagent. It has a wide range of uses and is often a key raw material in the field of pharmaceutical synthesis. It can participate in many reactions to make specific drugs. For example, synthesizing a certain type of anti-cancer agent, with its characteristics, the structure of molecules can be precisely constructed, and the drug power can be exerted.
In the field of materials science, it also has its uses. It can be an element in the synthesis of materials with special properties, making the material have unique photoelectric properties, and is used in new display materials.
And in organic synthesis chemistry, it is an important intermediate. It can generate a wide range of organic compounds through various reaction pathways, expanding the scope of organic synthesis, providing powerful tools for scientific research and industrial production. It is actually widely used and of critical value in many fields.
Research & Development
There is a chemical substance today, named 3 - Fluoro - 4 - Methoxybenzeneboronic Acid. We study this substance as a scientific researcher.
In the course of research, explore its structure in detail, analyze its physicochemical properties. Observe its reaction state, study the reaction mechanism, and hope to understand its laws in various chemical changes.
In order to seek development, seek new uses. Try it in the fields of medicine and materials, and explore its potential. If it is in medicine, it can make special agents; if it is in materials, it can create novel things.
After months of research, we have achieved something at the beginning. However, the road to development is long, and we still need to keep seeking. In the future, this research achievement will benefit the world and contribute to the progress of chemistry and the rise of science and technology.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it must be observed. Today there is 3-Fluoro-4-Methoxybenzeneboronic Acid, and the study of its toxicity is quite important.
Observe its chemical properties, or involve toxicity. In the context of the experiment, observe its response to various things in detail. Take the white rat as an experiment, feed a small amount, and for a while, the white rat is impatient and uneasy, and its food and drink gradually decrease. And look at its impact on green plants, touch the yellow leaves and wither. It can be seen that this substance is a sign of toxicity.
The depth of toxicity still needs to be investigated. Under different doses, the reaction may be different. And in the environment, decomposition and transformation also need to be studied in detail. It is based on the study of toxicity, and it should not be ignored. It should be done to ensure the safety of people and the environment.
Future Prospects
Today there is a thing called 3 - Fluoro - 4 - Methoxybenzeneboronic Acid. I look at this compound, which is unique in nature and has a wide range of uses. In the field of organic synthesis, it can be used as a key reagent to facilitate the progress of many delicate reactions.
Looking to the future, I am convinced that its development will not be limited. With the advance of science and technology, the stronger the power of research and development, the more it can emerge in the creation of medicine, providing new paths for healing diseases; or it can shine in the field of materials science, giving rise to novel materials to meet diverse needs. We should devote ourselves to our research and explore its endless potential, in order to contribute to future progress, so that the future of this thing is like the rising sun, shining brightly.
Where to Buy 3-Fluoro-4-Methoxybenzeneboronic Acid in China?
As a trusted 3-Fluoro-4-Methoxybenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluoro-4-Methoxybenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main application fields of 3-Fluoro-4-Methoxybenzeneboronic Acid?
3-Fluoro-4-methoxyphenylboronic acid, which is an extremely important chemical reagent in the field of organic synthesis, plays a pivotal role in many key application fields.
First, in the field of medicinal chemistry, its application is quite extensive. Because of its unique chemical structure, it can participate in the construction of a variety of drug molecules. In the process of many new drug development, it is often used to participate in arylation reactions to accurately build the drug activity skeleton, thereby improving the activity, selectivity and pharmacokinetic properties of the drug. For example, in the development of some anti-tumor drugs, with the help of 3-fluoro-4-methoxyphenylboronic acid to participate in the reaction, specific functional groups can be ingeniously introduced to enhance the ability of the drug to bind to tumor cell targets, thereby improving the efficacy.
Second, in the field of materials science, it also has outstanding performance. It can be used to prepare materials with special photoelectric properties. By reacting with other organic or inorganic monomers, polymer materials with specific structures and functions are constructed. These materials show good application potential in organic Light Emitting Diodes (OLEDs), solar cells, etc. For example, in the preparation of OLED materials, the materials obtained by its participation in the reaction can improve the luminous efficiency and stability, providing the possibility for the realization of high-performance OLED devices.
Third, in the field of fine chemicals, as a key intermediate, it is used for the synthesis of various fine chemicals. In the synthesis of products such as fragrances and dyes, 3-fluoro-4-methoxyphenylboronic acid can be used as a starting material or an important reaction intermediate. Through a series of chemical reactions, fine chemicals with specific structures and properties can be synthesized to meet the market demand for high-quality, special-function fine chemical products.
What are the synthetic methods of 3-Fluoro-4-Methoxybenzeneboronic Acid?
The synthesis method of 3-fluoro-4-methoxyphenylboronic acid often involves several paths. One is to use 3-fluoro-4-methoxybromobenzene as the starting material and pass through the Grignard reaction. First, 3-fluoro-4-methoxybromobenzene and magnesium chips are mixed in an inert solvent such as anhydrous ether or tetrahydrofuran, and under appropriate temperature and initiation conditions, the Grignard reaction occurs to generate the corresponding Grignard reagent. This reagent is extremely sensitive to air and water, and the operation needs to be carefully protected by inert gas. Subsequently, the Grignard reagent is reacted with borate esters, such as trimethyl borate or triethyl borate, and the reaction is completed. After the hydrolysis step, it is treated with a dilute acid solution to obtain 3-fluoro-4-methoxyphenylboronic acid. After that, the product is purified by extraction, drying, column chromatography or recrystallization.
Another common method is the palladium-catalyzed Suzuki coupling reaction derivatization path. 3-Fluoro-4-methoxyhalobenzene (such as chlorobenzene or bromobenzene) and borate esters are used as raw materials, in the presence of palladium catalysts (such as tetra (triphenylphosphine) palladium, ligands (such as tri-tert-butyl phosphine, etc.) and bases (such as potassium carbonate, sodium carbonate, etc.). The reaction conditions are relatively mild and the selectivity is good. After the reaction is completed, pure 3-fluoro-4-methoxyphenylboronic acid can be obtained through similar post-treatment processes, such as filtration of catalysts, extraction and separation of products, drying and purification.
In addition, there are also synthetic routes using 3-fluoro-4-methoxyaniline as the starting material. It is first converted into a diazonium salt by diazotization reaction, and then reacted with boric acid or borate ester to form the target product. During this process, the diazotization reaction needs to strictly control the temperature and reaction conditions to prevent side reactions from occurring. Subsequent operations also need to be separated and purified to obtain high-purity 3-fluoro-4-methoxyphenylboronic acid.
What are the physical and chemical properties of 3-Fluoro-4-Methoxybenzeneboronic Acid?
3-Fluoro-4-methoxyphenylboronic acid, this is a commonly used reagent in organic synthesis. Its physical and chemical properties are unique and are related to the development of many chemical processes.
Let's talk about its physical properties first. This substance is usually a white to light yellow solid, stable at room temperature and pressure. Looking at its melting point, which is about 200-205 ° C, this melting point characteristic is crucial for identifying and purifying this substance. Due to different purity substances, the melting point may vary slightly. Its solubility in water is limited, but it is soluble in some organic solvents, such as dichloromethane, tetrahydrofuran, etc. This solubility allows chemists to choose a suitable solvent system according to specific needs in organic synthesis reactions to promote the reaction.
As for chemical properties, the boron atom of 3-fluoro-4-methoxyphenylboronic acid has electron-deficient properties, so it is easy to react with electron-rich reagents. Among them, the Suzuki coupling reaction is a classic example. In the presence of bases and palladium catalysts, it can react with halogenated aromatics or olefin halides to form carbon-carbon bonds, whereby complex organic molecular structures can be constructed, which are widely used in drug synthesis and materials science. Moreover, the fluorine atom and methoxy group on the benzene ring also affect its chemical activity. The fluorine atom has a strong electron-absorbing effect, which can enhance the electrophilicity of the benzene ring; the methoxy group is an electron-donating group, which can increase the electron cloud density of the ortho and para-site of the benzene ring. The two work together to make the electrophilic substitution reaction more prone to occur at specific positions on the benzene ring, which facilitates the synthesis of compounds with specific substitution modes. In addition, its boric acid group can undergo esterification, dehydration and other reactions under appropriate conditions, further expanding its application in organic synthesis.
3-Fluoro-4-Methoxybenzeneboronic Acid to pay attention to when storing and transporting
3-Fluoro-4-methoxyphenylboronic acid is a commonly used reagent in organic synthesis. When storing and transporting, pay attention to the following numbers.
First, the storage temperature is the key. This reagent should be stored in a low temperature environment, usually in a refrigerator, and the temperature should be -20 ° C. If the temperature is too high, it is easy to cause decomposition reactions, which in turn affects its chemical properties and purity. Due to the increase in temperature, the molecular movement intensifies, which will make its internal chemical bonds easier to break and cause decomposition.
Second, the humidity should not be underestimated. The reagent is quite sensitive to moisture and is prone to hydrolysis in contact with water. Therefore, it is necessary to ensure that the environment is dry when storing. It can be placed in a dryer, and the desiccant needs to be replaced regularly to maintain a dry environment. When transporting, the packaging also needs to have good moisture resistance to prevent the intrusion of external water vapor.
Third, the packaging material should be properly selected. It should be packaged with good sealing performance to avoid excessive contact with the air. Due to the oxygen and other ingredients in the air, it may react with reagents such as oxidation, causing it to deteriorate. Generally speaking, it is more common to seal glass bottles or plastic bottles, but it is necessary to ensure that the bottle body is not damaged and the bottle cap is tightly sealed.
Fourth, avoid severe vibration and collision during transportation. This reagent may cause packaging damage due to violent vibration. Once the packaging is damaged, it is difficult to ensure the stability of its storage environment, and it will also increase the risk of contact with external adverse factors, affecting its quality.
In short, when storing and transporting 3-fluoro-4-methoxyphenylboronic acid, factors such as temperature, humidity, packaging and vibration need to be treated carefully to ensure that its quality is not damaged.
What is the market price range for 3-Fluoro-4-Methoxybenzeneboronic Acid?
3-Fluoro-4-methoxyphenylboronic acid, the price of this product in the market is difficult to determine. The price often changes due to various factors, such as the supply and demand of the market, the cost of production, the quality of quality, and even the scale of trade.
In the past market conditions, if the supply and demand were similar, and the cost of production was not abnormal, the price might be stable in a certain range. However, the market is not constant, if the need is greatly increased, and the production is not rapid, the price will rise. If at some time, the electronic industry is prosperous, and if more of this product is required, the price will rise.
If the cost of production changes, the price will also move. If the price of raw materials is high, or the process is complicated and expensive, it will increase the cost and the price will rise accordingly. And the quality is different, and the price is also different. Those with high purity must be more expensive than ordinary products, because they can be used in high-end fields and require precise control of the manufacturing process, so the price is high.
The scale of the trade is also a factor. If you buy in bulk, you can often enjoy preferential prices; if you buy zero, the price may be higher. According to past market conditions, the price may range from a few yuan per gram to tens of yuan, but this is only an approximate number. The actual price shall be subject to the current market conditions. For the exact price, you can consult the chemical material supplier or check the quotation of the relevant trading platform to obtain real-time price information.