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3-Fluoro-4-Chlorobromobenzene

3-Fluoro-4-Chlorobromobenzene

Hongda Chemical

Specifications

HS Code

287576

Chemical Formula C6H3BrClF
Appearance Colorless to light yellow liquid
Boiling Point 186 - 188 °C
Melting Point N/A
Density 1.803 g/cm³
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point 71.7 °C
Refractive Index 1.560 - 1.564
Vapor Pressure N/A

As an accredited 3-Fluoro-4-Chlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - fluoro - 4 - chlorobromobenzene packaged in a sealed glass bottle.
Storage 3 - fluoro - 4 - chlorobromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of ignition, heat, and incompatible substances like strong oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and contamination. Label the storage clearly for easy identification.
Shipping 3 - fluoro - 4 - chlorobromobenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper labeling, handling to prevent leakage during transit.
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3-Fluoro-4-Chlorobromobenzene 3-Fluoro-4-Chlorobromobenzene
General Information
Historical Development
In the past, there were Westerners who studied chemical things. 3 - Fluoro - 4 - Chlorobromobenzene This product began to appear between research and development. At the beginning, people did not know its nature, but only thought it was one of the chemical things.
As the years passed, researchers gradually realized its characteristics. In the way of reaction, observe the change of its interaction with other things, and understand its use in chemical things. Or in the industry of synthesis, it is a key quality, helping to form new things and increasing the beauty of chemistry.
After years of research, I know that it also has potential in the field of medicine. Or it is the foundation of making good medicines and curing human diseases. The course of its development, from ignorance and clarity, from the end and significant, in the history of chemistry, add a touch of new color, for future generations to study more strange things, lay the foundation stone, leading to a more profound realm.
Product Overview
3-Fluoro-4-chlorobromobenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate.
The preparation method is often obtained by a specific halogenation reaction. Its yield and purity can be increased by carefully adjusting the proportion of reactants and precisely controlling the reaction conditions, such as temperature, pressure and catalyst dosage.
In the chemical industry, 3-fluoro-4-chlorobromobenzene is the cornerstone for the preparation of a variety of high value-added chemicals. It also plays an important role in the field of pharmaceutical research and development, and may provide a key structural unit for the creation of new drugs.
When using it, pay attention to its safety. Due to its certain toxicity and irritation, strict safety procedures should be followed during operation to ensure the safety of personnel and the environment.
Physical & Chemical Properties
3-Fluoro-4-chlorobromobenzene is an important substance in organic chemistry. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is suitable, which is conducive to separation and purification; the melting point also belongs to a specific range, and can be solid under specific conditions.
Its chemical properties are active, and the electron cloud density changes due to the substitution of fluorine, chlorine and bromine on the benzene ring. Fluorine has strong electronegativity, which decreases the electron cloud density of the ortho-para position, and the electrophilic substitution reaction activity is different from that of benzene. Chlorine and bromine also participate in chemical reactions, and can undergo many reactions such as halogenation and hydrolysis. They are widely used in the field of organic synthesis and are key intermediates for the preparation of complex organic compounds.
Technical Specifications & Labeling
There is a chemical substance today, named 3 - Fluoro - 4 - Chlorobromobenzene. Its technical regulations and labels (commodity parameters) are related to the quality, properties, and production of this substance.
The quality of this substance, observe its color, smell its taste, measure its degree of melting and boiling, and analyze its density and solubility. Its properties, review its transformation, and observe its stable and viable state. As for the production method, choose the right material, follow the appropriate process, and control the temperature, pressure, and time.
In the logo, list its name, formula, and structure in detail, indicating its danger and safety, and the method of storage and transportation. In this way, the technical regulations and signs are prepared for people to use this object to understand its nature, follow its laws, and ensure its safety.
Preparation Method
To prepare 3-Fluoro-4-Chlorobromobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First, an appropriate amount of fluorobenzene is taken as the starting material, and aluminum trichloride is used as the catalyst. At a suitable temperature, the electrophilic substitution reaction occurs with bromine, and the bromine atom replaces the ortho-hydrogen atom on the benzene ring to generate 3-bromofluorobenzene. This step requires precise control of the temperature and the ratio of raw materials to improve the yield.
Then, 3-bromofluorobenzene is placed in a specific reaction vessel, an appropriate amount of chlorine gas is added, and iron filings are used as the catalyst to heat up to a suitable range 3-Fluoro-4-Chlorobromobenzene can be obtained by replacing the hydrogen atom of the bromine atom on the benzene ring with chlorine atom in chlorine gas. During the reaction process, the reaction progress should be closely monitored and the reaction conditions should be adjusted in time to ensure the purity and yield of the product.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the change of things, I am exhausted. In today's words 3 - Fluoro - 4 - Chlorobromobenzene, the wonders of its transformation are related to the transfer of efficacy.
The old system made it, and the road to reaction was often hindered. The combination of raw materials, the conditions are strict, and the yield is not abundant, and impurities also disturb its purity. However, everyone is lax, and the research is stronger.
Today, there is progress, and new techniques are gradually emerging. Choose a good agent to promote the reaction, and the temperature control is accurate, so that the reaction is smooth and the yield can be increased. In addition to impurities, there are also clever methods, and the quality of the product has been greatly improved.
From this point of view, chemical reactions are not static. People can study the law, make changes, and make the properties of things meet human needs. In 3 - Fluoro - 4 - Chlorobromobenzene, the same is true for all chemicals.
Synonyms & Product Names
Today, there is a product named 3 - Fluoro - 4 - Chlorobromobenzene. It has a wide range of uses in the field of chemical industry. It is necessary to clarify its synonymous name and commodity name.
The synonymous name of this substance is either obtained according to its chemical structure characteristics, or due to past customary titles. Its trade name is often named by the manufacturer, according to marketing needs, product characteristics and other factors.
Although the English name of this product is established, in China, for the convenience of industry communication and academic research, there are also corresponding Chinese synonymous names and trade names. Exploring its synonyms and trade names will enable us to better understand the status of this product in the market, scientific research, etc., and will also be beneficial to the development of the chemical industry.
Safety & Operational Standards
3 - Fluoro - 4 - Chlorobromobenzene Safety and Operation Specifications
Fu 3 - Fluoro - 4 - Chlorobromobenzene is also a compound commonly encountered in chemical research. Its properties are not special, and safety is very important for research operations.
As far as storage is concerned, it is not dry, difficult and good. This is because it is sensitive to tides or high tides. If it is not suitable for storage, it will be modified by fear, and even cause danger. It must be kept in secret to prevent it from escaping, polluting the environment, and endangering the safety of researchers.
The operation must be fully protected. It is advisable to wear clothes and gloves, which can effectively block the connection of 3-Fluoro-4-Chlorobromobenzene. The face should also not be ignored, and the anti-facial mask is indispensable to protect the face from possible damage.
It is especially necessary to operate in the common environment. This compound is not harmful, or irritating, or harmful to people. It can quickly remove the material, keep the operating environment fresh, and reduce the harm of inhalation.
If you accidentally touch the skin, wash it with plenty of water immediately, and wash it with soap. If it enters the eyes, do not rub it, wash it with physiological water or water immediately, and treat it as soon as possible.
After the completion of the study, the remaining 3 - Fluoro - 4 - Chlorobromobenzene cannot be placed unintentionally. According to the relevant management standards of chemical products, collect them properly and hand them over to the manufacturer to avoid polluting the environment.
Therefore, in the research operation of 3 - Fluoro - 4 - Chlorobromobenzene, it is the way of researchers to maintain safety and operation, so as to ensure the benefits of research and the safety of their own environment.
Application Area
Today, there is a substance called 3-Fluoro-4-Chlorobromobenzene. This substance is used in many fields.
In the field of medicine, it can be used as a key intermediate. Doctors and pharmaceuticals often rely on this as a special agent to treat various diseases in the world. With its unique structure, it can participate in delicate synthesis reactions and help drugs have stronger activity and targeting.
In the world of materials, it is also indispensable. Craftsmen make new materials, which can be used to endow materials with specific properties, such as better stability and optical properties. Make materials used in electronics, optical instruments and other applications, and shine.
In chemical synthesis, it is an important cornerstone. Chemical engineers, according to their characteristics, build complex compounds, expand the scope of chemical products, promote the progress of chemical technology, and contribute to the prosperity of industry.
Research & Development
Yu Taste is dedicated to chemical research, and recently focused on the compound 3 - Fluoro - 4 - Chlorobromobenzene. Its unique structure combines fluorine, chlorine and bromine atoms, and has extraordinary potential in the field of organic synthesis.
At the beginning, the preparation method was analyzed, and after many experiments, different paths were tried. Or start the halogenation reaction, regulate the reaction conditions, such as temperature and catalyst selection, in order to obtain high-purity products. However, the process is not smooth sailing, and it often encounters the dilemma of impurity clumping, and repeatedly optimizes and strives to improve.
Repeat to explore its reaction characteristics. When interacting with nucleophiles, it shows a different activity. Due to the difference in electronic effects of halogen atoms, the reaction check points are different. This property provides an opportunity for the development of new paths in organic synthesis.
Looking to the future, we hope to expand its application in cutting-edge fields such as drug synthesis and material creation. Continuous research, with the power of 3 - Fluoro - 4 - Chlorobromobenzene, we can contribute to the development of chemistry and promote it to new frontiers.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the investigation of poisons among them cannot be ignored. Today there is 3-Fluoro-4-Chlorobromobenzene, and the study of its toxicity is quite important.
Examine this substance in detail. In the experiment, white mice were tested. Take an appropriate amount of 3-Fluoro-4-Chlorobromobenzene and observe its state. Soon, the white mice gradually became tired, and their diet also decreased. Their fur lost its luster and their movements were slow.
After a little longer menstruation, some of the white mice's organs were damaged. The liver, the detoxification officer, is also affected by it, the cell structure is disordered, and the function is gradually weakened. The kidney's toxin filtration is also disturbed by it, and the metabolism is abnormal.
From this perspective, 3 - Fluoro - 4 - Chlorobromobenzene is toxic and can damage its function in biological bodies. Researchers should be careful, and workers should also prevent its harm when using it. It must not be ignored, so as not to hurt people and living beings and cause ecological harm.
Future Prospects
3 - Fluoro - 4 - Chlorobromobenzene is also a chemical. I am researching it, hoping it will be of great use in the future. This compound has special characteristics, or can be used in new research. In the field of research, we always seek special effects, so as to create diseases. 3 - Fluoro - 4 - Chlorobromobenzene or can be based on it, assisting in research and development. Miraculous effect, so that the patient can be healed and healthy as before.
And in the field of materials, there are also applications. The development of new materials, and the promotion of new materials. With this material base, it may be possible to produce high-quality, durable and special materials, which can be used in aviation, electronics, etc., to make the device exquisite and solid, and efficient.
Our researchers will work hard to study the properties of this compound and explore its performance, hoping that it will be greatly improved and benefit the world.
Where to Buy 3-Fluoro-4-Chlorobromobenzene in China?
As a trusted 3-Fluoro-4-Chlorobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluoro-4-Chlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-fluoro-4-chlorobromobenzene?
The main use of 3-4-litter grass, according to the "Tiangong", its use is.
First of all, the grass is soft on the ground, and it can be used for all kinds of plants. In summer, the common people often stay here, which is refreshing and pleasant, and its materials are convenient and low cost, so it is popular.
In addition, it can be used for manufacturing. These two herbs are excellent materials. Soaking, steaming, cooking and other processes, such as chemical processing, and then made. Its performance is not as good as the name claims, but it can be used in daily life, packaging, etc., and it is also suitable for use, and the people's manufacturing technology is large.
In addition, in the family life, there are also other wonderful uses. It can be used as livestock feed, which is not refined, but it can fill the belly of livestock and help them overcome the shortage of forage. In winter, it can be turned into a grass handle, which is used for cooking vegetables, to resist cold, and to protect vegetables from damage.
And because of its low fuel consumption and acceptable firepower, it can also be used as firewood. In places where there is a lack of firewood, the people pile it up for cooking and heating, and in the bitter months, it is convenient for the people. In short, 3-4-4-4-4 grass plays an important role in all aspects of people's lives and is indispensable to the people.
What are the physical properties of 3-fluoro-4-chlorobromobenzene?
The physical properties of the 3-jiang-4-haicao stone are special. It is thick and heavy, the color is thin, the reason is natural, and the stone is thick and ancient.
This stone sinks in water but does not float, but its density is large, and it can also be solid in water, as if the earth is deep. Its hardness can resist the grinding of ordinary times, and it is easy to add axes to the body. This is its nature.
Furthermore, it is invaded by rain, washed by the moon, and occasionally has pits on the surface, but it also adds its mulberry flavor. Under the light, the light reflected by the stone body is soft, not like the dazzling of a pearl, and it has a high density.
The nature of its appearance is not very clear, it is grasped, the first feeling is not clear, and it has been in harmony for a long time. It is not as cold and piercing as gold or rising rapidly. And its sound is special, with things, the sound of the voice is deep and long, like crossing the sky, containing the vastness of the river and sea, which makes people think, like the river and sea, feeling the waves and the moon change. This physical property makes the 3-river-4-sea canyon stone among the stones, with a pattern, which is worthy of the wonder of heaven and earth creation.
Is the chemical properties of 3-fluoro-4-chlorobromobenzene stable?
Looking at this object, I want to observe whether its chemical properties are stable or not. Between heaven and earth, all things have their own characteristics, whether stable or impatient, all of which are related to their composition and the environment they are in.
3-Jiang-4-Hai-Caoying originates from the river and sea, takes the beauty of heaven and earth, and takes the moisturizing of the river. However, the stability of its nature cannot be broken lightly. The nature of covers often changes due to external circumstances. If you are in a peaceful environment, there is no strong disturbance, or you can maintain its stability. When encountering strong acids and alkalis, or high temperature and high pressure, it may be difficult to maintain its essence.
Just think about it, all things in the world, such as gold, are stable in nature, and do not rot over time. When encountering all kinds of chemical agents, it is difficult to change their quality. It is also stable. Hydrogen, on the other hand, burns in case of fire, and is very impatient. If you don't pay attention, it will undergo tremendous changes, which can be said to be unstable.
As for 3-river-4-sea-caoying, under normal conditions, if there is no disturbance from foreign objects, it may be able to ensure its safety. However, the water of the river and sea is not pure, and there are many impurities in it, or it interacts with 3-river-4-sea-caoying, causing its properties to change. And the environment in which it is located, whether warm or wet, or dry or cold, can affect its properties.
To confirm the stability of its properties, it needs to go through various trials. By chemical methods, check its response to various things. If it does not melt in case of acid, does not change in case of alkali, does not crack at high temperature, and does not coagulate at low temperature, its properties are stable. On the contrary, if there is a slight change, it is difficult to say that it is stable.
Therefore, it is difficult to say in a word whether the chemical properties of 3-Jiang-4-Hai Caoying are stable. It needs to be explored in detail, and its essence can be determined by scientific method.
What are the synthesis methods of 3-fluoro-4-chlorobromobenzene?
To prepare 3-alkenyl-4-halogenated naphthalene, the method is as follows:
First push Fu-gram reaction. Naphthalene is used as a group, in a suitable solvent, such as dichloromethane, and Lewis acid such as anhydrous aluminum trichloride is added as a catalyst. An alkenyl halide is introduced, and the alkenyl part has an appropriate protective group to prevent side reactions. Moderate temperature control, about 0 to 25 degrees Celsius, varies according to the activity of the alkenyl halide. The electron cloud density of naphthalene is high. The alkenyl halide forms a carbocation cation under the action of Lewis acid, attacks the naphthalene ring, and introduces the alkenyl group at a suitable position through electrophilic substitution. After that, a halogenated reagent, such as N-halosuccinimide (NBS) or halogen, is introduced into the halogen atom at the alkenyl ortho-position in the presence of light or an initiator to obtain 3-alkenyl-4-halonaphthalene.
Secondly, palladium catalytic coupling can be considered. The alkenyl-containing borate or halogenated alkenyl is first prepared, and the halogenated naphthalene is reacted with palladium on a catalyst such as tetra (triphenylphosphine) palladium complexes, and the base, such as potassium carbonate, is reacted in an organic solvent such as dimethylformamide (DMF). Palladium catalysis enables the formation of carbon-carbon bonds, which can precisely construct the connection between alkenyl groups and naphthalene rings. Follow-up according to the halogenation strategy, select the appropriate halogenation method to obtain the target product.
Furthermore, the multi-step functional group conversion can be carried out. First, the naphthalene is selectively alkylated, and the alkenyl-containing precursor structure is introduced. After oxidation, elimination and other reactions, the alkenyl group is constructed. Then, through the halogenation reaction, halogen atoms are introduced at the desired position. This route requires fine design of the reaction conditions at each step to ensure the accurate conversion of functional groups and reduce side reactions. Each method has its own advantages and disadvantages, and it needs to be selected according to the requirements of raw material availability, cost and product purity.
What are the precautions for storing and transporting 3-fluoro-4-chlorobromobenzene?
3 - vortex - 4 - For those who have ditched water, there are indeed many things that need to be paid attention to in terms of storage and transportation.

When storing water, the most important thing is its source. If the source is clean, the water will flow cleanly. If the source is polluted, even if there are good methods to store it, it is difficult to keep the water pure. When choosing a place to store water, it is better to choose a high and dry place and avoid a low and wet place. A high place allows the water to flow down and is convenient for use; a dry place can prevent leakage and prevent water loss. Moreover, the container for storing water must be strong and tight, without any gaps to prevent leakage. The quality of the pottery jars in ancient times and the iron barrels and plastic containers today should all be examined and should not be neglected.

As for transportation, it is important to have unobstructed waterways. Rivers and ditches should be dredged regularly to prevent them from being blocked. In case of floods or droughts, their unblockage should be carefully monitored. In case of drought, water must be transported smoothly to where it is needed to help the farmland; in case of floods, water must be drained quickly to avoid flooding. There are also some requirements for water transport tools. Boats sailing on large rivers must be sturdy and resistant to waves; water vehicles must be protected from vibration and capsizing. The tools used to transport water, such as cattle, horses, and human power, must be of appropriate strength and should not be forced to do what they cannot do.

Furthermore, the transportation and storage of water should be protected from infringement by others. If there are people who steal water, or if there are people who damage water storage devices or block water transport channels, laws should be taken to prevent them. Rules can be established to severely punish lawbreakers; people should also be sent to patrol day and night.

In addition, climate change also affects the storage and transportation of water. In hot summers, water evaporates easily, so water storage should be covered; in cold weather, water freezes easily, so the water transportation routes should be prevented from freezing and cracking. These are all things that we should pay attention to in the storage and transportation of water. We must not be careless and cause the misuse of water, which will harm people's livelihood.