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3-Fluoro-4-Chloro Iodo Benzene

3-Fluoro-4-Chloro Iodo Benzene

Hongda Chemical

Specifications

HS Code

261586

Chemical Formula C6H3ClF I
Molecular Weight 260.447 g/mol
Appearance colorless to light yellow liquid
Boiling Point 204 - 206 °C
Melting Point N/A
Density 2.074 g/cm³
Solubility insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point 87.8 °C
Refractive Index 1.605
Purity usually high - purity products are 98% or higher

As an accredited 3-Fluoro-4-Chloro Iodo Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluoro - 4 - chloro iodo benzene packaged in a sealed glass bottle.
Storage 3 - Fluoro - 4 - chloro iodo benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent evaporation and exposure to air and moisture, which could potentially lead to decomposition or unwanted reactions. Use storage facilities compliant with chemical safety regulations.
Shipping 3 - fluoro - 4 - chloro Iodo Benzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper handling to prevent spills and maintain safety during transit.
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3-Fluoro-4-Chloro Iodo Benzene 3-Fluoro-4-Chloro Iodo Benzene
General Information
Historical Development
I will study the formation of 3 - Fluoro - 4 - Chloro Iodo Benzene. Ancient scholars, in the field of chemistry, although the knowledge is not as detailed as it is today, the heart of exploration has not been slightly reduced.
At the beginning, everyone's understanding of this kind of compound was still shallow, and only some of its characteristics were known. Later, after unremitting research by various sages, the method of its synthesis was discovered. First, various raw materials are combined with each other according to a specific order and appropriate temperature.
During this period, various attempts are made, but there are gains and losses. Or because the raw materials are not pure, or due to improper heat, the results are not as expected. However, everyone was not discouraged, repeatedly inferred and improved the technique.
With the passage of time, the synthesis method is becoming more and more perfect, the yield is gradually higher, and the quality is better. This compound is gradually used in the fields of medicine and materials, laying the foundation for the rise of chemistry in later generations.
Product Overview
There is a substance named 3 - Fluoro - 4 - Chloro Iodo Benzene. It is an organohalogenated aromatic hydrocarbon containing fluorine, chlorine and iodine halogen atoms in the benzene ring. The fluorine atom has strong electronegativity, which reduces the electron cloud density of the benzene ring and makes the reaction activity different from usual. Chlorine atoms affect the spatial structure and chemical properties of molecules. Although the iodine atom is large, in certain reactions, due to the low C-I bond energy, the easily broken bond participates in the reaction, or it is a key check point for nucleophilic substitution and coupling reactions.
This substance has attracted much attention in the field of organic synthesis and can be used as a key intermediate to build complex organic structures through various reaction paths. Its unique structure endows potential value in pharmaceutical research and development, and may lay the foundation for the creation of new drug molecules. However, its synthesis requires precise conditions and technologies to obtain high-purity products for subsequent research and application.
Physical & Chemical Properties
3-Fluoro-4-chloroiodobenzene, its physical state is mostly solid at room temperature. Looking at its color, it often appears like white, with a slightly pure color. This substance has a specific melting point, with a melting point of about [X] ° C and a boiling point near [X] ° C. Due to the influence of halogen atoms in the structure, the intermolecular forces change, resulting in the melting point having its own characteristics.
Its solubility is quite critical. It has a certain solubility in common organic solvents such as ethanol and ether, and can be dissolved and dispersed, because the molecules and solvents can form appropriate forces. In water, the solubility is very small, because it is an organic halogen, which is very different from polar water, and follows the principle of similar compatibility. In terms of chemical activity, the presence of fluorine, chlorine and iodine atoms on the benzene ring makes it have unique reactivity. The electron cloud density of the benzene ring is changed by halogens, which is conducive to the occurrence of electrophilic substitution reactions, and halogens can participate in many reactions such as nucleophilic substitution, making them an important raw material for organic synthesis.
Technical Specifications & Labeling
3-Fluoro-4-chloroiodobenzene is also a chemical product. Its process specifications and identification (commodity parameters) are related to the quality and use of this product.
To make this 3-fluoro-4-chloroiodobenzene, a specific method is required. The raw material is selected, the ratio is compatible, and the temperature and time of the reaction are all fixed. If the raw material is pure, it is related to the purity of the product. If the reaction temperature is high, it will be fast, or it will be heterogeneous; if the temperature is low, it will be slow, and the yield will drop.
In terms of identification, remember its name "3-Fluoro-4-Chloro Iodo Benzene" in detail, mark its formula, remember its weight, describe its properties, such as color and taste, melting point, and clear its danger, to be used by the police. According to this process specification and identification (product parameters), the quality and safety of 3-fluoro-4-chloroiodobenzene can be guaranteed.
Preparation Method
This product of 3 - Fluoro - 4 - Chloro Iodo Benzene is first and foremost known for its raw materials. It is based on fluoride, chloride and iodine-containing agents, which is the foundation of the preparation.
Its production process involves first combining fluorochlorinated benzene. According to a specific method, temperature and pressure are controlled to phase the two to obtain an intermediate of fluorochlorobenzene. Then, iodine-containing substances are introduced, and iodine is incorporated into its structure through ingenious reaction steps. This step requires precise control of the reaction conditions, such as the choice of catalyst and the amount of dosage, which are all about success or failure.
The reaction step is initially fluorochlorine copolymerization, which is done gently. When the intermediate is formed, it is transferred to the access of iodine. After each step, it must be refined to remove impurities and keep pure.
As for the catalytic mechanism, using a specific catalyst can promote the speed of the reaction and reduce the energy of activation. It touches the reactants to form a viable complex, leading the reaction along the easy path, so as to achieve the purpose of efficient production of 3-Fluoro-4-Chloro Iodo Benzene. In this way, the product can be obtained.
Chemical Reactions & Modifications
The chemical modification of 3-fluoro-4-chloroiodobenzene is the most important research. Now.
In this compound, the three atoms of fluorine, chlorine and iodine are each specialized. Fluorine atoms, because of their low performance, often cause the density of benzene to change, and affect the reaction activity. Chlorine atoms, because of their low performance, are not suitable for fluorine, but also have high performance. Iodine atoms, because their atoms are half large, can be used for good de-radicalization, and can be substituted like a chemical.
To change their properties, the method of nuclear substitution can be used. To attack the atoms on benzene with active nuclei, new derivatives may be obtained. Or take advantage of its poor atomic activity, step by step, and refine it. In this way, it is important to explore the field of chemical and reverse modification and the application of extensible compounds. It is of great value in materials and material research, and it is a new way of research.
Synonyms & Product Names
I heard that there is a thing called 3 - Fluoro - 4 - Chloro Iodo Benzene. This thing has a wide range of uses in the field of chemistry. Its synonyms are also what we should investigate.
Cover all things in the world, and the names are different, or due to differences in regions, or differences in customs, the same is true for chemical things. 3 - Fluoro - 4 - Chloro Iodo Benzene, or other names, are used to describe the properties, shapes, and uses of this substance. These synonyms and trade names have important meanings in academia and industry. When scholars study its nature and use, they need to clarify its various titles in order to be correct. Merchants sell it, but also rely on the accurate name to communicate information.
Our generation of chemical researchers should carefully examine their synonyms and commodity names, so as to know all the information about this thing, which is beneficial to scientific research and application. Only by knowing its name can we make good use of it and contribute to the progress of chemistry.
Safety & Operational Standards
3 - Fluoro - 4 - Chloro Iodo Benzene Safety and Operation Specifications
Husband 3 - Fluoro - 4 - Chloro Iodo Benzene is an important substance in chemical research. If you want to make good use of it, you must first clarify its safety and operation specifications to ensure that everything goes smoothly and is safe.
#1. Storage essentials
This substance should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Do not mix with oxidants, strong acids, strong alkalis and other substances. Because of its chemical properties, it is active and encounters with various substances. It is afraid of violent reactions and dangerous situations. The storage container shall be tightly sealed to prevent its volatilization and leakage, harming people and the environment.
#2. Rules of Operation
When operating, appropriate protective equipment must be worn. Wear chemical safety glasses to protect your eyes from splashing liquid; wear protective clothing to keep your body intact; wear rubber gloves to prevent skin contact with it. The operation should be carried out in the fume hood, so that the volatilized gas can be discharged in time, so as not to inhale into the body and damage health.
When taking it, the action should be slow and stable to avoid spillage. If it is accidentally spilled, clean it up immediately. First cover and absorb with inert materials such as sand and vermiculite, and then carefully collect it in a covered container. Dispose of it properly according to regulations, and do not discard it at will.
#3. Emergency measures
In case of skin contact, rinse with plenty of running water immediately, at least 15 minutes, and then seek medical attention. If entering the eyes, also rinse with plenty of water, lift the eyelids, ensure that the rinse is complete, and then rush to the doctor. If you inhale accidentally, leave the scene quickly to a fresh air place to keep breathing smoothly. If breathing is blocked, apply artificial respiration and seek medical attention quickly.
In short, in the research and application of 3 - Fluoro - 4 - Chloro Iodo Benzene, safety is the first priority, and the operation is in accordance with regulations, so that the research can be successful and the safety of the person and the environment can be ensured.
Application Area
Today there is a thing called 3 - Fluoro - 4 - Chloro Iodo Benzene. This thing has its uses in many fields.
In the field of medicine, it can be used as the basis for synthesizing wonderful medicines. With its unique structure, it can cleverly combine with other things to make a good medicine for healing diseases and relieve the pain of patients.
In the field of materials, there are also extraordinary things. It can be used to make new materials, endowing materials with specific properties, or increasing their strength, or changing their conductivity, so that the materials are suitable for more ingenious places.
Furthermore, in the realm of scientific research and exploration, it is an important reagent. Help researchers detect microscopic changes, study the nature of matter, open up unknown secrets, contribute to academic progress, promote all kinds of research, and move forward deeper and farther.
Research & Development
Today there is a product named 3 - Fluoro - 4 - Chloro Iodo Benzene. As a chemical researcher, I have been very attentive to the research and development of this product.
This compound has a unique structure and specific properties. The combination of fluorine, chlorine and iodine atoms endows it with different chemical activities. After repeated experiments, the reaction with various reagents was observed, and the characteristics of the product were analyzed in detail.
In the research, efforts were made to optimize its synthesis path. The initial method was cumbersome and the yield was not ideal. Then I dedicated myself to studying, improving the process, simplifying the process, and increasing the yield. At the same time, consider its stability and application prospects. Under different environmental conditions, monitor its changes and hope to expand its application field.
Wuxin, through unremitting research and exploration, 3 - Fluoro - 4 - Chloro Iodo Benzene will be able to show important value in chemical, pharmaceutical and other fields, and contribute to the development of the industry.
Toxicity Research
Yu Taste is dedicated to the research of poisons, and recently focused on 3 - Fluoro - 4 - Chloro Iodo Benzene. The toxicity of this substance is related to people's livelihood and the environment, and cannot be ignored.
At the beginning of the research, the chemical structure of fluorine, chlorine, and iodine atoms were investigated in detail, which affected their activity and toxicity. After many experiments, animals were used as samples to observe their reactions after ingestion. At first, the test animals were slightly tired, moved slowly, and ate less. Then, some organs were abnormally characterized, liver function indicators fluctuated, and there were signs of kidney damage.
The degradation state of it in the environment was also investigated. In different media, such as soil and water, its decomposition rate and product were different. In water, degradation is slow, and the derived by-products are also potentially harmful.
In summary, 3-Fluoro-4-Chloro Iodo Benzene is not lightly toxic and poses a threat to both organisms and the environment. In the future, it is necessary to study its detoxification methods and control its spread in the environment to ensure the safety of all things.
Future Prospects
Wuyan 3 - Fluoro - 4 - Chloro Iodo Benzene has been around for a long time. Its properties are unique, and it has a wide range of uses. It has potential in the fields of medicine and materials.
Looking at the future, its development prospects are promising. In medicine, it may be able to assist in the research of new drugs and cure diseases. With its unique chemical structure, it can become the basis for targeted drugs, precise treatment, and reduce the suffering of patients.
In the field of materials, it is also expected to give birth to new materials. It may have excellent electrical conductivity and optical properties, creating a new situation for the electronics and optical industries.
Although there may be thorns in the road ahead, we who are scientific researchers should maintain a strong heart and study physics. With time, we will be able to fully develop the potential of 3 - Fluoro - 4 - Chloro Iodo Benzene, which will be used by the world and benefit all beings.
Where to Buy 3-Fluoro-4-Chloro Iodo Benzene in China?
As a trusted 3-Fluoro-4-Chloro Iodo Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Fluoro-4-Chloro Iodo Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-fluoro-4-chloroiodobenzene?
3-Jiang-4-The main use of sea mussel fenugreek, the cover of its materials can be used in many aspects.
In the way of medicinal use, sea mussel fenugreek has certain medicinal effects. Its mild nature may regulate human qi and blood, and help relieve some diseases and pains. Ancient healers often used it as medicine and processed it to treat diseases such as epigastric pain and poor qi and blood. Because of the ingredients it contains, it can act on the qi and blood of human meridians and collaterals to achieve the purpose of promoting justice and removing evil spirits.
In the way of eating, the meat of sea mussel fenugreek is tender and delicious. It can be cooked by a variety of cooking methods, such as steaming, to retain its original flavor, so that its tender quality and delicious taste can be fully displayed; or stewed and integrated into the soup to make the soup delicious and nourishing. It is rich in a variety of nutrients, such as protein, trace elements, etc., to provide the human body with necessary nutrients and nourish the body.
In terms of craftsmanship, the shell of sea mussel and husk has a unique shape and solid texture. It can be used by craftsmen to make all kinds of exquisite handicrafts through carving, polishing and other skills. Or for ornaments, placed on the table to add elegance; or for accessories, worn on the body, unique style. Its unique texture and shape, through ingenious processing, has become a carrier of culture and art.
In addition, at the level of cultural meaning, sea mussel husk also has a deep meaning. In traditional cultural concepts, it is often given auspicious and beautiful meanings. Such as symbolizing reunion and harmony, it means smooth life and happy family. During folk activities and festivals, objects or images related to sea musk husk often appear in it, conveying people's expectations and wishes for a better life.
What are the physical properties of 3-fluoro-4-chloroiodobenzene?
3-Jiang-4-Sea clam bead sharks, its physical properties can be studied. Sea clams are born at the intersection of rivers and seas. The shell is hard and elliptical, and its color is white or brown, with a certain luster. This is a sign of its physical appearance. The texture of the shell is hard and tough, which can resist the invasion of the outside world and protect its soft body.
As for the bead sharks, their body shape is slender, and the body surface has a special texture, which is streamlined, which is conducive to their swift swimming in the water. Its body surface is covered with fine scales, which are smooth to the touch. The color of the scales changes with the environment, either silver-white or blue-gray, which has a certain hidden effect.
Within the sea clam, a pearl can be conceived. The pearl is round and shiny, and has rich colors, including milky white, pink, and lavender. Its texture is warm and moist, and its hardness is moderate. The Mohs hardness is about 3, and it has good refractive properties. It shines brightly in light.
The fins of the shark bead are tough and elastic, and can swing flexibly in water to help it control direction and speed. Its skeletal structure is light and strong, which meets the needs of aquatic life. In addition, the eyes of the bead shark have a special structure, which is adapted to seeing objects in water and is sensitive to changes in light.
The physical properties of these things are closely related to their environment and survival habits, and each has its own wonders, making it a miraculous product of creation.
Is the chemical property of 3-fluoro-4-chloroiodobenzene stable?
3-4-4-Stones have their properties of transformation, and are they constant? This is a question about physical properties. Between heaven and earth, all things have their properties, but their properties are constant or changing, and cannot be generalized.
Looking at all things in the world, there are those who are constant in nature, and those who are transsexual. For example, gold and stone, their quality is firm and stable, and they are not easy to change over time. And water is a thing, which is shaped with the vessel, condensed when cold, and melted when hot, and its properties are often easy.
As for the 3-4-stone, although it is not detailed what it is, it is common sense that if it is a stone or the like, the stone property is more firm and stable, and the transformation property may also be relatively stable. The formation of a stone can only take shape after years of sedimentation and geological changes. It is established. If there is no strong disturbance from external forces, such as high temperature, strong acid, heavy pressure, etc., its transformation property should be maintained constant.
However, it is not completely certain. Things in the world are often impermanent. Even if it is a stone, if it is in a special situation, such as a place with abnormal geothermal conditions, or encounters long-term erosion by strong corrosive substances, its transformation property may also change.
Therefore, if you want to know whether the chemical properties of 3-4-stone are stable, you need to carefully investigate the environment in which it is located. When you encounter external forces, you cannot rashly break its chemical properties and stability just because it is stone. When you are cautious and investigate in detail, you can get its true meaning.
What are the synthesis methods of 3-fluoro-4-chloroiodobenzene?
There are many methods for synthesizing 3-ene-4-halogenated steroids, each of which has its own advantages. Here they are described as follows:
First, halogenated addition method. Select the steroid substrate containing the alkene bond and make it react with the halogenating agent under suitable conditions. For example, halogen elements such as chlorine and bromine, or halogenated hydrogen gases such as hydrogen chloride and hydrogen bromide are used as halogenating agents. During the reaction, the π electron cloud of the alkene bond is attacked by the electrophilic reagent of the halogenating agent to form a carbon positive ion intermediate, and then the halogenated negative ion is combined with it to obtain the halogenated steroid product. This method is simple and direct, but the regioselectivity is poor. The reaction conditions need to be carefully adjusted to increase the yield of the target product.
Second, nucleophilic substitution method. If the steroid substrate has a leaving group, such as a hydroxyl group, the halogen atom can be introduced through a nucleophilic substitution reaction. The hydroxyl group is first converted into a leaving group, such as p-toluenesulfonate, etc., and then reacts with halogen ions in the presence of suitable solvents and bases. The base can promote the nucleophilic attack of halogen ions and generate halogenated steroids. This method has better regioselectivity, but the steps are slightly complicated, and multiple steps are required to prepare a suitable substrate.
Third, free radical halogenation method. In the presence of an initiator, the free radical mechanism is used to realize the halogenation of steroids. Commonly used initiators include peroxides, etc. When heated or illuminated, the initiator decomposes to produce free radicals, grabs hydrogen atoms on the steroid substrate, and generates carbon free radicals. The carbon free radicals then react with the halogenating agent to obtain halogenated steroids. This method has mild conditions and can achieve halogenation at some special positions. However, the selective control of the reaction is difficult, and it is often accompanied by side reactions.
Fourth, the direct action method of halogenated reagents. Using special halogenated reagents, such as N-halogenated succinimide (NBS), N-halogenated acetamide, etc., these reagents can introduce halogen atoms into specific positions of steroid molecules with high selectivity under relatively mild conditions. Taking NBS as an example, it achieves halogenation reaction with steroid substrates under the action of light or initiator through the radical process of allyl or benzyl sites, with good regioselectivity and high yield.
What is the price range of 3-fluoro-4-chloroiodobenzene in the market?
In today's world, among the shops in the market, it is quite difficult to determine the price of 3-Jiang-4-Sea Clam Beads. The width and narrowness of the price are related to various reasons.
First, it depends on the quality of the beads. If the beads are round, shiny, and flawless, the price of such excellent beads will be very high. Or it can reach hundreds of gold or even thousands of gold. And if the beads are slightly less well-shaped and the luster is slightly darker, the price will drop sharply, or only a few tens of gold ears.
Second, it is related to the supply and demand of the city. When there are many beads in the market, and the supply is thin, the price will rise. For example, during the festival, or when the rich family is building construction and making Chinese clothing jewelry, the price of mussel beads is often high. On the contrary, if the supply exceeds the demand, the price will drop.
Third, the distance of the origin is also related. Those produced nearby, because of the saving of many transshipment fees, the price may be slightly flat. If you come from a foreign land and travel through land and water, the cost is quite huge, and the price will increase.
Generally speaking, the price of the ordinary 3-river-4-sea mussel beads may be between tens of gold and hundreds of gold. If it is a rare treasure, or if you encounter rich people competing to buy it, its price is difficult to limit, or thousands of dollars are unknown.