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3-Fluoro-2-Methoxybenzeneboronic Acid

3-Fluoro-2-Methoxybenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

738853

Name 3-Fluoro-2-Methoxybenzeneboronic Acid
Chemical Formula C7H8BFO3
Molecular Weight 171.946 g/mol
Appearance Solid
Melting Point 143 - 148 °C
Solubility Soluble in common organic solvents
Purity Typically high purity available in commercial products
Density Data may vary, typical range for boronic acids
Stability Should be stored properly to avoid decomposition
Reactivity Reacts with various reagents in organic synthesis
Cas Number 1150114-72-4

As an accredited 3-Fluoro-2-Methoxybenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - fluoro - 2 - methoxybenzeneboronic Acid in a sealed, labeled container.
Storage 3 - Fluoro - 2 - methoxybenzeneboronic acid should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could lead to degradation. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid chemical reactions.
Shipping 3 - fluoro - 2 - methoxybenzeneboronic acid is shipped in well - sealed containers. Packaging ensures protection from moisture and physical damage. It's transported following strict chemical shipping regulations for safe delivery.
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3-Fluoro-2-Methoxybenzeneboronic Acid 3-Fluoro-2-Methoxybenzeneboronic Acid
General Information
Historical Development
Wenfu 3 - Fluoro - 2 - Methoxybenzeneboronic Acid This thing, its prosperity, originated in the study of the sages. At the beginning, everyone explored in the realm of transformation, wanting to understand its nature and study its use. Over the years, all the gongs tried their best, or tried various methods, or adjusted materials, hoping to get good results.
At the beginning, I explored the path of its synthesis, but there were many mistakes, but I was determined to remain unchanged. Later, I gradually got the essentials, optimized its method, so that the yield rose and the purity was better. As a result, it has emerged in the fields of medicine and materials, and is important in the industry. Looking at the path of its development, it is like sailing against the current. The sages worked hard to break through the obstacles and achieve today's entry. It is the luck of the chemical industry and lays the foundation for the future expansion of the new chapter.
Product Overview
Today there is a product called 3 - Fluoro - 2 - Methoxybenzeneboronic Acid. This is a chemical product with unique properties. Looking at its appearance, or in the shape of white crystals, fine particles, crystal clear and pure.
This product has a wide range of uses in the field of chemistry, and is often a key agent in organic synthesis. It can participate in many reactions and help create new compounds. Because of its fluorine, methoxy and boric acid groups, the structure is unique, giving it special chemical activity.
Synthesis of this product requires delicate methods, temperature control, time adjustment, and specific processes to obtain its pure product. In scientific research, it is the cornerstone of exploring new substances and new reactions, and chemists rely on it to explore the unknown and promote the progress of chemistry. It is an indispensable element in the chemical world.
Physical & Chemical Properties
3-Fluoro-2-methoxyphenylboronic acid is also a chemical product. Its material has the same physical and chemical properties. Its color or color is as light as the crystal, which can be observed by the eye. Its fusion is also an important physical property, which is determined by the specific properties, which is determined by the molecular force.
In terms of chemical properties, the boric acid group makes it have a certain activity. It can be used for the biochemical reactions of many chemical compounds, such as the reaction of catalysis. This is the most important method in the synthesis. This reaction shows the activity of its boric acid group, which can replace the reaction of other reactions to form new carbon-carbon compounds, so as to create the best.
Its solubility is also known to be soluble in some solvents. This property is advantageous for its dispersion, reaction, and other steps in the synthesis operation. All this physical and chemical properties are of great significance in chemical research and synthesis.
Technical Specifications & Labeling
There is a product today, named 3 - Fluoro - 2 - Methoxybenzeneboronic Acid. In terms of technical specifications and identification (commodity parameters) of the product, we should study it in detail.
The preparation of this product requires a certain method. The selection of raw materials must be excellent and the ratio is appropriate. When reacting, temperature, humidity, duration, etc. must be precisely controlled. If the temperature control is not correct, the product will be impure or of poor quality.
Its identification is also important. The parameters of the product should be detailed, including ingredients, purity, and characteristics. The label of purity should be accurate to the value, so that the user can understand its quality. The description of the properties also needs to be accurate, such as color, state, etc. In this way, the object can be displayed in full detail in front of the user, in order to meet the requirements of technical specifications and labels, and meet the needs of the user.
Preparation Method
The preparation method of 3-fluoro-2-methoxyphenylboronic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, and halogenated aromatics and borate esters are commonly used as starting materials. The production process of preparation uses halogenated aromatics and borate esters under palladium catalysis through Suzuki as a common route. The reaction steps are rigorous. First, halogenated aromatics, borate esters, palladium catalysts, bases and solvents are put into the reactor in a specific ratio, and heated and stirred in a nitrogen-protected atmosphere. Control the reaction temperature in a moderate range, such as 80-100 degrees Celsius, and react for several hours to make the reaction sufficient. In the catalytic mechanism, the palladium catalyst promotes the formation of carbon-boron bonds between halogenated aromatics and borate esters, and the base helps to activate the borate esters to accelerate the reaction process. In this way, 3-fluoro-2-methoxyphenylboronic acid can be efficiently prepared to ensure product quality and yield.
Chemical Reactions & Modifications
I tried to study 3 - Fluoro - 2 - Methoxybenzeneboronic Acid. Its reaction rate is related to various reaction paths and conditions. In the initial study, the reaction rate was not ideal, the product was impure, and there were many side reactions.
Then think about changes to seek the good reaction. Looking at the structure of its molecules, think about the appropriate reagent and catalytic agent. The temperature and pressure of easy reaction, adjust the ratio of reagents. After repeated tests, under a specific temperature and pressure, with a certain catalytic agent, adjust the ratio of reagents, the reaction rate increased significantly, and the reaction rate decreased. The purity of the product also increased, and better results were obtained.
This research is also based on chemical response and chemical properties, and it is necessary to try and change, so as to get into the situation. In 3-Fluoro-2-Methoxybenzeneboronic Acid, the solution of chemical response and sexual properties is also further advanced.
Synonyms & Product Names
3-Fluoro-2-methoxyphenylboronic acid, also known as other. There are many different names, all of which are used to identify its nature and quality. In the field of our chemical research, various different names have their own uses, or they are inherited from the past names, or they are given new names according to their characteristics.
At the beginning of ancient chemical research, this substance was first obtained. Due to the limitations of cognition at that time, it was given a name according to some of its appearances and preliminary properties. Later, as the research deepened, more characteristics were discovered, and for the purpose of accurate expression, new synonyms were obtained. Although the names are different, they all refer to this 3-fluoro-2-methoxyphenylboronic acid. Many different names, such as stars in the vault of chemical research, help us to recognize this object from different perspectives, and in the process of research, each has its own contribution to jointly promote the deepening and expansion of this material understanding.
Safety & Operational Standards
3 - Fluoro - 2 - Methoxybenzeneboronic Acid Safety and Operation Specifications
3 - Fluoro - 2 - Methoxybenzeneboronic Acid is an important compound in chemical research. During its experimental operation, safety comes first, and many specifications need to be strictly followed.
#1. Storage Safety
This compound should be stored in a dry, cool and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Due to its chemical properties, if it is not stored properly, or interacts with moisture or high temperature, it will cause deterioration or cause dangerous reactions. Therefore, the storage place must be kept in a suitable environment, and the storage status should be checked regularly to ensure safety.
#2. Operation Specifications
1. ** Personnel Protection **: All those involved in the operation of this compound need to wear appropriate protective equipment. Protective clothing can prevent it from contacting the skin, and protective gloves must be chemically resistant to avoid direct touch. Goggles are also indispensable to prevent it from splashing into the eyes and causing damage.
2. ** Operation Process **: The operation should be carried out in the fume hood, which can effectively discharge volatile gas and reduce indoor pollution. When taking the compound, the action should be stable and accurate, and the exact amount should be taken according to the experimental requirements to avoid waste and pollution. During the mixing or reaction process, strictly follow the established steps to control temperature, time and other conditions. If there is any abnormal phenomenon, such as heat, discoloration, gas generation, etc., the operation should be stopped immediately and properly disposed of.
3. ** Waste Treatment **: After the experiment is completed, the remaining 3 - Fluoro - 2 - Methoxybenzeneboronic Acid and related waste should not be discarded at will. It needs to be collected by chemical waste treatment specifications and handed over to professional institutions for disposal. It must not be dumped into sewers or ordinary trash cans to avoid polluting the environment.
In short, in the research and use of 3 - Fluoro - 2 - Methoxybenzeneboronic Acid, safety and operation standards must be kept in mind to ensure the smooth experiment, personnel safety and environmental protection.
Application Area
3-Fluoro-2-methoxyphenylboronic acid, a chemical substance, has a wide range of applications. In the process of pharmaceutical creation, it can be used as a key intermediate to assist in the study of pharmaceutical power. In the field of organic synthesis, it also has extraordinary functions, which can promote the construction of various organic molecules.
Looking at the past classics, the wonders of chemical industry often rely on the combination of various raw materials. 3-Fluoro-2-methoxyphenylboronic acid, with its unique structure, has emerged in many reactions. In the process of drug research and development, with its characteristics, it may be able to develop new agents and cure various diseases. In the field of materials science, it may also contribute to the birth of new materials.
This chemical product, like the stars in the chemical industry, is tiny but bright, contributing to the development of various fields and attracting many researchers to explore its endless possibilities.
Research & Development
In recent years, I have dedicated myself to the research of 3 - Fluoro - 2 - Methoxybenzeneboronic Acid. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its preparation method. After several attempts, the ratio of raw materials and reaction conditions were carefully studied. Occasionally, the reaction yield was not good, or the product purity was not as expected, but I was not discouraged.
After repeated debugging, the process was improved, and the suitable catalyst and precise temperature were used to control it, and finally the product with high yield and high purity was obtained.
At the same time, its activity in various reactions was also observed. It interacts with many organic reagents, presenting a different reaction path and opening up a new path for organic synthesis.
Looking to the future, we hope to use this as a foundation to further expand its application scope, shine in the fields of medicine, materials, etc., promote the development of this field, and contribute to the academic community and industry.
Toxicity Research
Today's study of 3 - Fluoro - 2 - Methoxybenzeneboronic Acid, its toxicity study is the key. Looking at the ancient methods of studying poison, we must carefully examine it. In this thing, we should first explore its dissolution in various media with the care of ancient methods, and observe the changes caused by its contact with other things. Repeat it with all kinds of living beings to try it, and observe the differences in its eating, movement, and physical signs. The detailed records have observed, do not leak anything. Gu Yun: "The slightest difference is a thousand miles away." Toxicity research is related to the lives of all people, and we must devote our efforts to make sure that the conclusion is conclusive, to understand the intensity of its toxicity, and the wide range of harm. We think that those who use this thing in future generations will learn from it, to protect the safety of the people, and to avoid disasters.
Future Prospects
Fu 3 - Fluoro - 2 - Methoxybenzeneboronic Acid is a chemical product that we have dedicated ourselves to researching. Looking at the present, although there have been some achievements, there are still many things that can be expanded in the future development.
Its unique nature may emerge in the field of medicine, assist in the development of new drugs, cure various diseases, and seek well-being for the common people. It is also expected to be used in material science to improve materials, increase their properties, and make materials more tough, durable, and have special functions.
We should be enterprising, unremitting research, and tap its potential. With time, we will be able to make it shine in various fields and achieve extraordinary achievements. This is our vision for the future, and it is also the key to scientific research.
Where to Buy 3-Fluoro-2-Methoxybenzeneboronic Acid in China?
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Frequently Asked Questions

As a leading 3-Fluoro-2-Methoxybenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main application fields of 3-fluoro-2-methoxyphenylboronic acid?
3-Hydroxy-2-aminobenzoylbenzoic acid, this substance has a wide range of uses. In the field of medicine, it is a key intermediate. In the synthesis of many drugs, it is necessary to use this as a starting material for subsequent reactions. For example, in the preparation of some drugs for the treatment of cardiovascular diseases, with the help of its unique chemical structure, through a series of chemical reactions, a molecular structure with specific pharmacological activities can be constructed to help the drug play the role of regulating cardiovascular function.
In the dye industry, it also plays an important role. It can be used as a key component in the synthesis of dyes of a specific color. Due to its own chemical properties, it can endow dyes with excellent stability and color brightness. Like some high-grade dyes used in textile printing and dyeing, through the rational use of 3-hydroxy- 2-aminobenzoyl benzoic acid, fabrics can show a long-lasting bright color after printing and dyeing, and it is not easy to fade after multiple washes.
Furthermore, in the field of organic synthetic chemistry research, it is often used as a model compound. Researchers have in-depth understanding of various organic reaction mechanisms through the exploration of their chemical reaction characteristics. For example, nucleophilic substitution reactions, oxidation-reduction reactions, etc. in their molecular structures, thus providing theoretical basis and practical experience for the development of organic synthesis methodologies, and promoting the continuous development of organic synthetic chemistry.
What is the synthesis method of 3-fluoro-2-methoxyphenylboronic acid?
To make 3-alkyne-2-methoxyphenylboronic acid, you can follow the following ancient method.
First take an appropriate amount of 3-bromo-2-methoxyphenylacetylene and place it in a clean reactor. This compound is the starting material for the reaction, and its chemical properties are active, laying the foundation for subsequent reactions.
Add an appropriate amount of n-butyllithium to the kettle. This is a strong base. Under a low temperature environment, such as about -78 ° C, slowly add it dropwise. When n-butyllithium meets 3-bromo-2-methoxyphenylacetylene, it initiates a lithium halogen exchange reaction. Due to the low temperature, the reaction is controlled, and the butyl of n-butyl lithium captures the bromine atom to form a lithium intermediate, which is extremely active and needs to be handled with care.
Then, the reaction system is heated to about -10 ° C, and then trimethyl borate is slowly added. Trimethyl borate reacts rapidly with the lithium intermediate, and the lithium atom binds to the methoxy oxygen in trimethyl borate to form the target product precursor.
After the reaction is completed, carefully quench the reaction with an appropriate amount of dilute acid, such as dilute hydrochloric acid. This step is designed to neutralize the alkaline substances in the system and free the product from the complex reaction mixture.
Finally, the pure 3-alkyne-2-methoxyphenylboronic acid can be obtained by extraction, column chromatography and other separation and purification methods. During the extraction process, a suitable organic solvent, such as dichloromethane, is used to transfer the product from the aqueous phase to the organic phase. Column chromatography achieves fine separation according to the difference in the distribution coefficient of the product and the impurity in the stationary phase and the mobile phase, and obtains a high-purity target product for subsequent research or application.
What are the physical and chemical properties of 3-fluoro-2-methoxyphenylboronic acid?
3-Hydroxy-2-methylaminophenylpyruvic acid, this is an organic compound. Its physical and chemical properties are as follows:
Looking at its properties, it is mostly white to light yellow crystalline powder under normal conditions, and may change color slightly under the action of specific ambient light and air. This substance has a certain melting point, about [X] ° C. Its purity can be tested by means of melting point determination.
In terms of solubility, it has limited solubility in water, but it has good solubility in some organic solvents such as ethanol and dichloromethane. In ethanol, at a specific temperature, [X] grams of this substance are soluble per [X] grams of ethanol, which facilitates its utilization in organic synthesis and separation and purification operations.
When it comes to chemical properties, the hydroxyl group, methylamino group and the structural part of phenylpyruvate in its molecular structure all give it unique reactivity. Hydroxyl groups can participate in esterification reactions, and under the action of catalysts with acids, corresponding ester compounds are formed. Methylamino groups are alkaline and can neutralize with acids to form salts. The structural part of phenylpyruvate acid can participate in various reactions such as nucleophilic substitution and oxidation. For example, under the action of strong oxidants, the benzene ring may be oxidized, and the side chain may also undergo corresponding oxidative transformation.
In addition, this substance is more sensitive to acid-base environments. In acidic environments, its amino groups may protonate, causing molecular charge distribution to change, affecting its solubility and reactivity; in alkaline environments, hydroxyl groups may deprotonate, which will also cause property changes. During storage and use, pay attention to the impact of environmental pH on its stability.
What are the precautions for 3-fluoro-2-methoxyphenylboronic acid during storage and transportation?
3-Divergent-2-aminoxy benzoic acid, if you hide it, you will have to pay attention to it.
It is appropriate to hide it in the first place. It is appropriate to be in a place where things are busy and dry, to avoid the exposure of sunlight and the invasion of sunlight. When exposed to sunlight, I am afraid that its chemical properties will be easy, it will invade it, or cause it to rot. And it is necessary to isolate other things, especially avoid the same acid, in order to prevent biochemical combination and loss of its essence.
It is necessary to wrap it and seek it. Wrap it with materials to prevent it from being damaged by earthquakes on the way. If the packaging is not good, its contents will not only be lost, but may endanger the surrounding. Furthermore, the speed of the delivery also needs to be controlled. It is appropriate to be high, not to be high, high or cause it to decompose; nor to be low, for fear of causing it to change its shape and affect its use.
The person who sent it also knows the nature of this thing. Keep it safe and avoid it from being shaken and collided. On the way, always check the appearance of its bag. If there is any problem, it should be placed quickly. And the ship sent also needs to be cleaned and dyed, so that foreign objects are not damaged.
Where this is the case, it is necessary to store 3-2-aminobenzoic acid. Only then can it be kept safe and safe for use.
What is the approximate market price of 3-fluoro-2-methoxyphenylboronic acid?
Wen Jun inquired about the market price of 3-hydroxy- 2-aminobenzoylbenzoic acid, which is an important compound in the field of fine chemicals. However, its price fluctuates frequently and is influenced by many factors, so it is difficult to determine the specific price.
The first to bear the brunt is the price of raw materials. The synthesis of this compound requires specific raw materials. If the origin and output of the raw materials change, or the market supply and demand imbalance, the price of raw materials will rise, and the cost of 3-hydroxy- 2-aminobenzoylbenzoic acid will also rise, and its market price will rise. On the contrary, the raw materials are abundant and cheap, and the product price may drop.
Furthermore, the market supply and demand trend has a great impact. If this compound is in strong demand in the pharmaceutical, dye and other industries, but the supply is limited, the price will rise; if the market is saturated and the supply exceeds the demand, the merchant will sell its goods, and the price may be lowered.
Process technology is also related. Advanced synthetic processes can reduce production costs and enhance product competitiveness. If there is technological innovation in the industry, the cost will decrease and the price may also decrease; however, the research and development cost of new technologies is high. If it is not widely used, the product price may remain high.
Regional factors cannot be ignored either. In different places, the price may be different due to differences in logistics costs, tax policies, etc. In prosperous cities, logistics is convenient, or due to fierce market competition, the price may be slightly lower; in remote places, logistics is inconvenient, and the cost will increase, and the price may be slightly higher.
In summary, the market price of 3-hydroxy- 2-aminobenzoylbenzoic acid is uncertain, ranging from hundreds of yuan per kilogram to thousands of yuan. It needs to be determined comprehensively according to the current market conditions and the number of transactions. For the exact price, please consult the relevant chemical product suppliers, trading platforms or industry insiders to get the latest market conditions.