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3-(Difluoromethoxy)Iodobenzene

3-(Difluoromethoxy)Iodobenzene

Hongda Chemical

    Specifications

    HS Code

    526011

    Chemical Formula C7H5F2IO
    Molecular Weight 270.01
    Appearance Colorless to light yellow liquid
    Boiling Point Around 104 - 106°C at 15 mmHg
    Density Typically around 1.95 g/cm³
    Solubility Soluble in common organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Purity Commercially available in high purity, often >97%

    As an accredited 3-(Difluoromethoxy)Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of 3-(difluoromethoxy)iodobenzene, securely sealed.
    Storage Store 3-(difluoromethoxy)iodobenzene in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. It should be stored in a tightly - sealed container, preferably made of a material resistant to chemical corrosion, to prevent leakage and degradation. Avoid exposure to moisture which could potentially initiate unwanted reactions.
    Shipping 3-(Difluoromethoxy)iodobenzene is shipped in well - sealed, corrosion - resistant containers. Strict safety protocols are followed, ensuring proper labeling. Shipment is coordinated to maintain stability during transit, minimizing risks.
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    3-(Difluoromethoxy)Iodobenzene 3-(Difluoromethoxy)Iodobenzene
    General Information
    Historical Development
    I am dedicated to the study of the formation of 3- (Difluoromethoxy) Iodobenzene. In the past, it was difficult and ineffective to explore this compound. At the beginning, all the wise people were trapped in the difficulty of finding raw materials and complicated reactions. However, under unremitting research, there is a turning point. Start with a specific halogenated benzene as a base, coupled with delicate ligands, temperature control and pressure regulation, so that the reaction can gradually stabilize. Although the process has been difficult, the discomfort of the catalyst and the disturbance of side reactions have been encountered, but everyone has worked together. After years of research, improved the steps and optimized the conditions, and finally the preparation of 3- (Difluoromethoxy) Iodobenzene has become more mature. At present, this method can be produced stably, paving the way for subsequent research and application. This is the work of various scholars and is also one of the proofs of chemical evolution.
    Product Overview
    Today there is a thing called 3- (Difluoromethoxy) Iodobenzene. Its shape and color, at first glance, are to clarify the flowing liquid, reflecting light and shining, without variegated colors mixed in between, pure and clear.
    Smell its gas, slightly pungent but not strong, although it has a breath, it is not pungent and intolerable. As for its properties, it is still said to be stable at room temperature, but when it encounters a hot topic of fire, or a dramatic change, it cannot be ignored.
    The system of this thing has gone through several methods, and the compatibility of raw materials and the temperature are all fixed. For the use of various chemical industries, it is quite good at it, which can be the basis for the synthesis of other things, and can help the reaction to form a variety of compounds. In the field of chemical industry, such as masonry in Guangsha, although it is minimal, it is indispensable, and it is of great value in the advancement of industry and the rise of science and technology.
    Physical & Chemical Properties
    3 - (difluoromethoxy) iodobenzene, an organic compound. Its physical and chemical properties are related to the characteristics of this compound. Looking at its shape, at room temperature, or as a colorless liquid, it has a special odor. As far as its boiling point is concerned, it has a specific value due to the force between molecules, so that it gasifies at the corresponding temperature. Its density is also an important physical property, reflecting the compactness of the substance.
    Chemically, it has unique reactivity due to the iodine atom and difluoromethoxy group. Iodine atoms can participate in nucleophilic substitution reactions, and difluoromethoxy groups affect the electron cloud distribution of molecules, making this compound a key intermediate in organic synthesis, reacting with many reagents, showing rich chemical changes, which is important in the field of organic synthetic chemistry.
    Technical Specifications & Labeling
    There is currently a substance 3 - (difluoromethoxy) iodobenzene, and I would like to state its technical specifications and identification (product parameters). The technical specifications of this substance are related to purity. When striving for purity, there should be few impurities, so as not to affect its properties. Its physical properties, color should be clear, no variegated colors should be mixed in it, and the taste should also have the inherent taste of this substance, no peculiar smell. As for the label, the name "3 - (difluoromethoxy) iodobenzene" must be clearly marked on the package to prevent confusion. It is also necessary to list the product parameters in detail, such as molecular weight, molecular formula, etc., so that the user can understand its chemical characteristics. In this way, the standard technical specifications and labels should be used to ensure that this product is accurate and safe when used and circulated.
    Preparation Method
    In order to prepare 3- (Difluoromethoxy) Iodobenzene, the method of preparation is the first raw material. When a suitable starting material is taken, such as a compound containing a benzene ring, and the substituent on it needs to be synthesized. In the
    preparation method, the reaction steps are essential. The nucleophilic substitution reaction can be used to make the reagent containing fluoromethoxy group interact with the iodobenzene derivative. The process needs to control the temperature, duration and ratio of the reactants. The catalytic mechanism of
    cannot be ignored. Find an efficient catalyst to promote the reaction speed and yield. Such as some metal catalysts or organic bases, the catalytic work can be initiated in the reaction. In this way, through exquisite raw materials and production processes, controlled reaction steps, and catalytic mechanisms, it is expected to obtain 3- (Difluoromethoxy) Iodobenzene with good purity.
    Chemical Reactions & Modifications
    The chemical reaction and modification of 3 - (difluoromethoxy) iodobenzene have been quite successful. The reaction of this compound is difficult due to its specific structure. The methods tried in the past either had low yield or complicated side reactions.
    After repeated exploration, we changed to a specific catalyst to regulate the temperature and humidity of the reaction, and actually improved the reaction path. The reaction that was originally difficult was gradually smooth and the yield was greatly improved. And there were few by-products produced, so the purity was guaranteed.
    With this modification, 3- (difluoromethoxy) iodobenzene can be used in various fields of synthesis, or it can develop its greater ability, laying a more solid foundation for subsequent organic synthesis work, and hoping to open up a new path for future generations in chemical research.
    Synonyms & Product Names
    Today there is a thing called 3 - (difluoromethoxy) iodobenzene. This thing has a wide range of uses in the field of chemistry. Its aliases are also many, although the names are different, they are actually the same.
    We have studied this thing for a long time and know its properties well. Looking at the method of its manufacture, we must follow the delicate technique to get a pure product. It is effective in all chemical things, either as a raw material or as a medium.
    The same thing has different names in the city, but it all refers to this 3 - (difluoromethoxy) iodobenzene. It is of great significance to the development of industry and the progress of science. We should study it carefully and make good use of it to promote the improvement of chemical technology and contribute to the development of the world.
    Safety & Operational Standards
    Code for safety and operation of 3- (difluoromethoxy) iodobenzene
    Fu 3- (difluoromethoxy) iodobenzene is also a chemical research material. Although its nature is not extremely strong, it is related to safety and operation regulations and must not be ignored.
    During storage, choose a cool, dry and well-ventilated place. Avoid it from being close to fire and heat sources to prevent it from being exposed to heat and causing accidents. Store it in a sealed container to prevent it from contacting air and moisture and causing component variation.
    As for the access operation, the operator must first wear appropriate protection. Wear protective goggles to protect your eyes from splashing in; wear protective gloves to avoid skin contact with it. Do it in the fume hood, so that the volatile gas can be dissipated in time, so as not to gather in the room and cause harm to the human body.
    If it is unfortunate to touch the skin, quickly rinse with a lot of water and seek medical treatment. If it enters the eye, also quickly rinse with flowing water or normal saline, still need medical attention. If you inhale it accidentally, leave the scene quickly and go to a place with fresh air. If you feel unwell, seek medical help.
    Furthermore, after use, the waste should not be disposed of at will. When in accordance with the regulations on chemical waste disposal, it should be collected by classification and properly disposed of to prevent pollution of the environment and harm to life.
    In short, in the research and use of 3- (difluoromethoxy) iodobenzene, safety is the top priority, and the operation is in accordance with regulations, so as to avoid disasters and promote the smooth progress of the research.
    Application Area
    Today there is a product called 3 - (difluoromethoxy) iodobenzene. This chemical product has a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create novel and special drugs, cure various diseases, and save people from pain. In material science, it can contribute to the construction of special performance materials, or increase the stability of materials, or give them unique optical characteristics. In the fine chemical industry, it is indispensable for the preparation of high-end fine chemicals. With its unique chemical structure, it participates in various reactions, derives many useful products, and opens up new avenues for various application fields.
    Research & Development
    I have been studying chemical substances. Recently, I have been focusing on the compound 3 - (difluoromethoxy) iodobenzene. The method of its preparation is quite critical. It is necessary to consider the reaction conditions in detail, such as temperature, catalyst dosage, etc.
    After several tests, initial results have been achieved. However, if you want to achieve perfection, you still need to improve. In the reaction mechanism, we also have in-depth research, hoping to clarify the internal chemical changes.
    Looking at the development prospects of this compound, it has great potential. It may be able to emerge in the fields of medicine and materials. I should make unremitting efforts to study its properties and applications in depth, hoping to contribute to the progress of chemistry and promote its wide application to benefit the world.
    Toxicity Research
    The toxicity of 3- (Difluoromethoxy) Iodobenzene, a halogenated aromatic ether, is of great significance. I have carefully reviewed the classics and tested the experiments. This compound has a unique structure, containing fluoromethoxy and iodine atoms. After repeated trials, observe its interaction with biological systems. Observe the changes of cells, the activity of enzymes, and measure the route of metabolism.
    At the beginning, at a low concentration, there is no significant abnormality in the cells. However, the concentration gradually increases, the cell morphology begins to change, and the proliferation is inhibited. It may be due to the easy removal of iodine atoms, and the biochemical order after entering the cell is chaotic. And the existence of fluoromethoxy, or the hydrophobicity of molecules, makes it easy to accumulate in the lipid area and disturb the function of the membrane.
    And explore its effect on enzymes, specific enzyme activity decreased, biochemical reaction stagnation. It can be seen that this compound is very toxic, subsequent application development, should be careful, study its toxicology in detail to ensure safety.
    Future Prospects
    I have tried to study chemical substances, and today I am discussing the future prospects of 3 - (difluoromethoxy) iodobenzene. This chemical substance has unique characteristics and has immense potential in various fields. Looking at the research and development of medicine, it may be able to lay the foundation for the creation of new agents. With its special structure, it may be able to respond to the treatment of difficult diseases. In materials science, it is also expected to give birth to materials with novel functions and help the progress of science and technology. Although there may be obstacles in research and production at present, with time, we will be able to overcome it with the wisdom of everyone and our efforts. I am convinced that its future will shine brightly, bring many surprises and benefits to the world, and start a new chapter in chemical applications.
    Where to Buy 3-(Difluoromethoxy)Iodobenzene in China?
    As a trusted 3-(Difluoromethoxy)Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-(Difluoromethoxy)Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3- (Difluoromethoxy) Iodobenzene?
    3 - (difluoromethoxy) iodobenzene, this substance has a wide range of uses. In the field of organic synthesis, its position is pivotal. Due to its unique structure, difluoromethoxy coexists with iodine atoms, and can be used as a key intermediate to participate in the preparation of many complex organic compounds.
    First, in pharmaceutical chemistry, with its special structure, it can be used to construct molecular frameworks with specific biological activities. By reacting with other reagents, the molecular structure can be precisely modified, which in turn affects the interaction between drugs and targets, and improves the efficacy and selectivity of drugs. For example, in the development of some new anti-cancer drugs or antiviral drugs, 3- (difluoromethoxy) iodobenzene may serve as a starting material or a key intermediate to help create more effective therapeutic drugs.
    Second, in the field of materials science, it also has outstanding performance. Because its structure endows compounds with specific electrical and optical properties, it can be used to synthesize organic optoelectronic materials. For example, when preparing organic Light Emitting Diode (OLED) materials, the introduction of 3- (difluoromethoxy) iodobenzene structural units may optimize the luminous efficiency and stability of the materials, contributing to the improvement of display technology performance.
    Furthermore, in pesticide chemistry, this compound can be used as an important raw material for the synthesis of new pesticides. After proper chemical transformation, the synthesized derivatives may have highly effective insecticidal and bactericidal activities, and are environmentally friendly, contributing to the development of green and sustainable agricultural production.
    What are the physical properties of 3- (Difluoromethoxy) Iodobenzene?
    3 - (difluoromethoxy) iodobenzene is also an organic compound. It has unique physical properties and has attracted much attention in the fields of chemical industry and scientific research.
    Under normal temperature, it is mostly colorless to light yellow transparent liquid. This state makes it easy to disperse and mix in many reaction systems, providing convenience for the smooth development of chemical reactions. Its odor may have a special aromatic smell, but the strength of this smell often varies depending on the environment and concentration.
    When it comes to boiling point, it is in a specific temperature range due to the force between molecules. This temperature can change it from liquid to gaseous. The characteristics of this boiling point are of great significance in the operation of separation and purification. It can be effectively separated from the mixture by distillation according to the difference in boiling point.
    As for the melting point, it is also an important physical property. Under a specific temperature, it will melt from solid to liquid. The accurate determination of this temperature helps to identify the purity of the substance. The higher the purity, the narrower the melting point range.
    In terms of solubility, 3- (difluoromethoxy) iodobenzene exhibits good solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc., and can be miscible with various solvents. This property makes it widely used in organic synthesis reactions, participating as a reactant or solvent. In water, its solubility is poor, due to the dominant role of hydrophobic groups in the molecular structure.
    Density is one of the important markers of substances. The density of 3- (difluoromethoxy) iodobenzene may be different from that of water. This difference can be used as an important basis for judgment in operations such as liquid-liquid separation.
    In addition, its vapor pressure has a specific value at a certain temperature, and the vapor pressure is related to the degree of volatilization of the substance. This property is of great significance for safety precautions and the formulation of operating norms during storage and use. The above physical properties are interrelated and together determine the behavior and use of 3- (difluoromethoxy) iodobenzene in different scenarios.
    What are the synthesis methods of 3- (Difluoromethoxy) Iodobenzene?
    There are various ways to prepare 3 - (difluoromethoxy) iodobenzene. One is to use methoxy-containing benzene as the starting material, first through halogenation reaction, introduce iodine atoms at specific positions in the benzene ring. In this case, the halogenation reagents and reaction conditions need to be carefully selected to ensure that the iodine atoms are accurately added to the target check point. Commonly used halogenating reagents such as iodine elementals are matched with appropriate oxidizing agents, or specific iodizing reagents can be used to achieve this step under mild conditions.
    Then, the resulting iodine-containing methoxy benzene compound is subjected to difluoromethylation. This step can be achieved by various methods, such as the use of difluoromethylation reagents, such as difluoromethyl halides or active intermediates containing difluoromethyl. In the presence of suitable bases and catalysts, methoxy groups and difluoromethyl groups are substituted to form the key structure of 3- (difluoromethoxy) iodobenzene. During the reaction, the strength of the base, the type and amount of catalyst all have a significant impact on the efficiency and selectivity of the reaction, and need to be carefully regulated.
    Another idea is to use iodine-containing benzene as the starting material, and introduce suitable functional groups first, so that difluoromethoxy groups can be introduced later. For example, iodobenzene is first functionalized to form an iodobenzene derivative with a convertible group. Subsequently, the difluoromethoxy group is connected by the reaction between the group and the difluoromethylation reagent. This approach requires detailed optimization of the conditions of each step of the reaction to ensure the smooth progress of each step and the purity of the product.
    Furthermore, the positioning effect on the benzene ring can be exploited by designing a reasonable synthetic route. First, a group with positioning guidance is introduced to guide the introduction of iodine atoms and difluoromethoxy groups at the desired position. In the whole synthesis process, the separation and purification of the product after each step of the reaction is also crucial, and means such as column chromatography and recrystallization are often used to obtain high-purity 3- (difluoromethoxy) iodobenzene.
    3- (Difluoromethoxy) Iodobenzene What are the precautions during storage and transportation?
    For 3 - (difluoromethoxy) iodobenzene, many things should be paid attention to during storage and transportation. The nature of this compound may be more active, and the first environment should be selected when storing. It should be placed in a cool, dry and well-ventilated place, away from hot topics and open flames, to prevent chemical reactions caused by temperature, fire, or even danger.
    Packaging is also crucial. It needs to be packed with suitable packaging materials to ensure good sealing and prevent leakage. Because leakage not only damages materials, but also poses a risk of harm to the environment and people. If the packaging is damaged, it should be dealt with quickly without delay.
    When transporting, also need to be cautious. The carrier should be clean, dry, and free of impurities that cause the reaction of this compound. During transportation, it is advisable to drive slowly and steadily to avoid severe vibration and collision, causing damage to the package or causing internal reactions.
    In addition, people who handle and come into contact with this substance should be equipped with protective equipment, such as gloves, goggles, protective clothing, etc. Due to inadvertent contact, it may hurt the skin or eyes, and if inhaled or ingested, it may endanger health.
    In addition, the records of its storage and transportation should not be ignored. Write down the storage time, quantity, storage conditions, etc. in detail for traceability and management. In this way, it is necessary to ensure the safety of 3 - (difluoromethoxy) iodobenzene during storage and transportation.
    What is the market price range for 3- (Difluoromethoxy) Iodobenzene?
    I don't know what the market value of "3 - (Difluoromethoxy) Iodobenzene" is. This compound is not easily available, and its market value is determined by many factors.
    First, the ease of production is one of the main factors. If its synthesis requires a lot of steps, special raw materials or harsh reverse parts, the cost will be high, and the price will also be higher. Furthermore, the supply and demand of the market are large. If the demand is low, and the supply is limited, the price will rise; if the demand is low, the price may decline.
    In addition, the cost also affects its cost. Those with high cost are usually higher than those with low cost due to high cost. In addition, different suppliers also have different prices. Different companies have different cost control and cost-effective strategies, and the results are different.
    However, we have not yet obtained the market inspection, and we have not yet announced the price of the product. If you want to know the price, you can use the chemical raw material supplier, the chemical product trading platform, or the recent chemical market announcement to get the market.