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3-(Difluoromethoxy)Bromobenzene

3-(Difluoromethoxy)Bromobenzene

Hongda Chemical

Specifications

HS Code

846502

Chemical Formula C7H5BrF2O
Molecular Weight 223.014
Appearance Liquid (Typical)
Boiling Point Data may vary, around 180 - 190 °C under normal pressure
Melting Point Data may vary, typically low - melting solid or liquid
Density Data may vary, likely in the range of 1.6 - 1.8 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, dichloromethane
Flash Point Data may vary, need experimental determination
Vapor Pressure Data may vary, relatively low at room temperature
Stability Stable under normal conditions, avoid strong oxidizing agents

As an accredited 3-(Difluoromethoxy)Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle packaging for 3-(difluoromethoxy)bromobenzene chemical.
Storage 3-(Difluoromethoxy)bromobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions.
Shipping 3-(Difluoromethoxy)bromobenzene is shipped in accordance with chemical transport regulations. It's typically packed in sealed, corrosion - resistant containers to prevent leakage during transit, ensuring safety and integrity.
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3-(Difluoromethoxy)Bromobenzene 3-(Difluoromethoxy)Bromobenzene
General Information
Historical Development
The technology of chemical industry is changing with each passing day, and the research of substances is related to the world's fate. Today, there is 3 - (difluoromethoxy) bromobenzene, and its beginning is also the beginning. Researchers have devoted themselves to exploring the method of its synthesis. At the beginning, the technique was not mature, and the yield was quite low, but everyone was not discouraged and moved forward.
Over the years, the wisdom of chemistry has become clearer, and the method of technology has become more refined. Or improve the reagents, or optimize the process, and gradually increase the yield of 3 - (difluoromethoxy) bromobenzene, and the quality is also high.
Looking at the path of its development, from the difficult exploration at the beginning to the smooth progress later, it depends on the perseverance and wisdom of the researchers. Today, this thing is of great use in the fields of medicine and materials.
Product Overview
Today there is a substance called 3- (difluoromethoxy) bromobenzene. The properties of this substance are colorless and transparent, just like the clarity of autumn water. Its smell, although not pungent, still has a unique smell.
Looking at its structure, on the benzene ring, bromine atoms and difluoromethoxy groups are on one side each, and the layout is exquisite. The combination of the two gives the substance different characteristics. In terms of chemical properties, due to the activity of bromine, it can emerge in many reactions; the existence of difluoromethoxy groups adds a bit of stability.
3- (difluoromethoxy) bromobenzene is widely used in the chemical industry. It can either be a key raw material for organic synthesis, which can assist in the synthesis of many delicate compounds; or it can play an important role in the development of medicine, contributing to the birth of new pharmaceuticals. Its potential in various fields is still waiting to be developed, and it needs to be explored urgently.
Physical & Chemical Properties
Today there is a thing called 3- (Difluoromethoxy) Bromobenzene. Its physical and chemical properties are related to many things. As far as physical properties are concerned, the color state of this thing, at room temperature or in a liquid state, looks clear and has no variegated colors. Its smell, or has a special aromatic aroma, should not be smelled lightly to prevent damage to the body. Its density is different from that of water. It can be studied in detail when placed in water, floating or sinking. As for the boiling point, when heated to a certain temperature, it will boil and vaporize. This temperature is one of its characteristics.
When it comes to chemical properties, there are specific groups in its molecular structure. The fluorine atom is connected to the methoxy group, giving it unique activity. When it encounters a base, it may react and the molecular structure changes to form new compounds. When exposed to acid, it may also react differently, or break or recombine chemical bonds. Its chemical stability needs to be determined by many experiments to understand its changes in different environments, which is of great significance for chemical research and application.
Technical Specifications & Labeling
Process specification and identification (product parameters) of this 3 - (difluoromethoxy) bromobenzene. Prepare the raw materials first, the quantity needs to be accurate, and the quality must be high. In a clean kettle, put them in sequence, control the temperature appropriately, or bathe in water, or heat with fire, so that they should be slow and smooth. During the reaction, constantly measure variables, observe changes in color and taste, and be punctual. Do not overdo or underdo it. After finishing, analyze the purity, filter the impurities with a special filter, and then go through the method of distillation and extraction to improve its purity.
into the quality, the observation should be clear and transparent, and the smell should be odorless. Measure its degree, when it is in line with the preset, the impurity content must be slight. The logo is indicated on the bottle body, the name, quantity, purity, and production time and place of the book, and the danger and storage method are more noted. The user knows it clearly, and there is no risk of misuse. The craftsmanship abides by this specification, and the quality is marked with clear awareness, so as to obtain good production.
Preparation Method
The method of making 3 - (difluoromethoxy) bromobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be selected from pure bromobenzene and difluoromethanol. At the beginning of the production process, bromobenzene is placed in a special vessel and an appropriate amount of catalyst is added. This catalyst can activate the structure of bromobenzene and increase its reactivity.
Next, slowly inject difluoromethanol and control the reaction temperature in a suitable range, about 50 to 60 degrees Celsius. This temperature range can ensure the stable progress of the reaction. During the reaction step, the two molecules interact, and the bromine atom of bromobenzene and the hydroxyl group of difluoromethanol undergo a complex reaction process to generate 3- (difluoromethoxy) bromobenzene. The catalytic mechanism is that the catalyst reduces the activation energy of the reaction, making the reaction easier to occur. In this way, this product can be obtained.
Chemical Reactions & Modifications
I am dedicated to the research of chemical materials, and I have worked hard on the products of 3- (Difluoromethoxy) Bromobenzene. Its chemical reaction is related to the choice of reaction raw materials and the control of conditions. The method of the past, or the raw materials are rare, or the conditions are harsh, and the yield is not ideal.
Think about the way of change, in the raw materials, find more accessible and cheap alternatives; in the conditions, adjust the temperature, pressure, catalyst, and hope to change its activity. If the temperature changes, observe the change of molecular activity, and the temperature is high, the molecular movement will be dramatic, and the reaction will be easy; the same is true for the pressure, moderate pressurization, or promotion of the reaction.
The wonder of the catalyst is that although it does not participate in the structure of the final product, it can change the path of the reaction and reduce the energy of activation. With a good catalyst, the yield of 3- (Difluoromethoxy) Bromobenzene may be increased, and the quality may be increased. After various attempts, we have achieved good methods to make the preparation of this product more efficient and more economical.
Synonyms & Product Names
3 - (difluoromethoxy) bromobenzene, which has attracted much attention in the study of chemistry in China. Its synonymous names and commodity names are also important for investigation.
In the field of Guanfu chemistry, the same substance often has various names. 3 - (difluoromethoxy) bromobenzene, or it has another name for its characteristics, or it has another name for the product according to industry practice and regional differences.
The synonymous name, or derived from the analysis of chemical structure, interpreted its composition from different perspectives, resulting in various titles. As for the name of the product, merchants give it a unique name in order to recognize its characteristics and facilitate its circulation.
When I am researching, I carefully review all kinds of relevant literature to clarify the context of its synonyms and trade names. This is not only related to academic accuracy, but also of great benefit to the practice of the chemical industry. Only by understanding its many terms can we move smoothly between scientific research and production, avoid misunderstandings caused by different names, and make research and application smooth.
Safety & Operational Standards
About 3 - (difluoromethoxy) bromobenzene product safety and operating specifications
Fu 3 - (difluoromethoxy) bromobenzene is also one of the chemical products. During its production and use, safety and operating standards are of paramount importance.
In terms of storage, choose a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent them from being dangerous due to heat. This product should be placed separately from oxidants and edible chemicals, and must not be mixed to avoid chemical reactions and cause harm.
When operating, operators must undergo special training and strictly abide by the operating procedures. Wear appropriate protective equipment, such as protective glasses, gloves, etc., to protect your own safety. The operating environment should have good ventilation facilities. If it is operated indoors, ventilation equipment should be prepared to discharge harmful gases in time.
During the handling process, it must be handled lightly and lightly, and the container should not be damaged. If the container is damaged and the product leaks, emergency measures should be taken immediately. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, it is necessary to build a dike or dig a pit for containment, and transfer it to a special collector by pump for recycling or transportation to a waste treatment site for disposal.
Furthermore, the production and use sites should be equipped with suitable fire fighting equipment and leakage emergency treatment equipment. In the event of a fire, the appropriate fire extinguishing method can be selected according to the characteristics of the product.
In short, the safety and operating standards of 3 - (difluoromethoxy) bromobenzene are related to personal safety and environmental safety, and practitioners should follow them carefully and not slack off.
Application Area
Today, there is a product called 3 - (difluoromethoxy) bromobenzene, which has wonderful uses in many fields. In the field of pharmaceutical research and development, it can be a key raw material for the synthesis of special drugs, helping doctors overcome difficult diseases and relieve the pain of patients. In the field of materials science, based on this, new materials with outstanding performance can be made, or with extraordinary stability, or with unique optical properties, which can be used in high-end scientific and technological products to promote the progress of science and technology. In the fine chemical industry, it is also an important intermediate. After exquisite processing, it is converted into various fine chemicals to meet the diverse needs of people's livelihood. From this point of view, 3- (difluoromethoxy) bromobenzene is shining like a pearl in many application fields, playing a role that cannot be ignored, injecting vigorous impetus into the development of various industries.
Research & Development
Today there is a substance called 3- (Difluoromethoxy) Bromobenzene. I am a researcher of chemical substances, and it is very important to investigate this substance, which is related to research and progress.
At the beginning, explore its properties. After various experiments, we know its physical properties, such as color and taste, degree of melting and boiling, and energy of dissolution. We also study its chemical properties, observe its reaction with other substances under various conditions, in order to understand the rules of its reaction.
Second time, study its method. To obtain this substance, you need to find a suitable method. Examine the advantages and disadvantages of each method carefully, and choose the best one. Or modify the ancient method, or create a new way, hoping to improve the yield, reduce costs, and reduce pollution in the environment.
Furthermore, think about its use. Promote the ability of this substance in the fields of medicine and materials, expand its use, promote the progress of science and technology, and contribute to the development of the world. With the research of our generation, 3- (Difluoromethoxy) Bromobenzene will develop its strengths in various fields and assist in research and progress.
Toxicity Research
I recently focused on the toxicity study of 3- (Difluoromethoxy) Bromobenzene. This compound is used in industrial production more and more widely, but its toxic effects are not yet clear.
I investigated it with various experimental methods. Animals were used as samples to observe the physiological changes after ingesting this compound. Observe their behavior, eating, organ function, etc., and supplemented by cell experiments to explore their effects on cell structure and function.
Preliminary results show that 3- (Difluoromethoxy) Bromobenzene has certain toxicity. Animals may have abnormal behavior and signs of organ damage. Cell experiments also showed that cell viability decreased and morphology changed. However, this is only the beginning, and more experiments and detailed analysis are needed to clarify the full picture of its toxicity, provide evidence for its safe use and prevention of hazards, and protect people and the environment.
Future Prospects
Today there is a thing called 3- (Difluoromethoxy) Bromobenzene. We chemists have studied this thing for a long time. Looking at its properties, it has a unique structure and contains unlimited potential.
Looking to the future, this thing may shine in the field of medicine. With its characteristics, it may be possible to develop new drugs, cure various diseases, and save people from pain. In materials science, it is also expected to give birth to novel materials with excellent performance and wide application, making devices and instruments more sophisticated.
Furthermore, with the advance of science and technology, the synthesis method will be optimized, the yield will be improved, and the cost will be reduced. At that time, 3- (Difluoromethoxy) Bromobenzene will become more popular, and it will become indispensable in industrial production, scientific research and exploration. We should study diligently, hoping to achieve this vision as soon as possible, for the well-being of future generations, and to promote this material to bloom brightly.
Where to Buy 3-(Difluoromethoxy)Bromobenzene in China?
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Frequently Asked Questions

As a leading 3-(Difluoromethoxy)Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3- (difluoromethoxy) bromobenzene?
Bis (ethoxyacetyl) anthraquinone is widely used in industry. It is used in the field of organic synthesis.
First, it is an important intermediate for synthetic dyes. In the dye industry, through a series of chemical reactions, di (ethoxyacetyl) anthraquinone can be used to produce a variety of dyes with bright colors and good fastness. For example, some anthraquinone disperse dyes, with their specific molecular structure, by condensation and substitution with other compounds, make the dye molecules have suitable hydrophobicity and affinity for fibers. It can be widely used in dyeing processes such as polyester fibers, giving fabrics brilliant color and lasting non-fading.
Second, it is also useful in the paper industry. It can be used as a cooking aid. During the pulp cooking process, adding this substance can promote the dissolution of lignin, reduce the cooking energy consumption and time, and improve the yield and quality of pulp. Its mechanism of action is to form a certain interaction with lignin to weaken the connection between lignin and cellulose, making lignin easier to remove from fiber raw materials, and at the same time less damage to cellulose, thereby ensuring the strength and other properties of pulp.
Third, it can also be seen in the field of medicine and chemical industry. Although it is not directly used as a drug, it can be used as a starting material or intermediate for the synthesis of some biologically active compounds. With the help of chemical modification and transformation, molecular structures with specific pharmacological activities are constructed, providing an important material basis for the development of new drugs. For example, by modifying its structure and introducing specific functional groups, it is possible to explore lead compounds with potential anti-tumor, antibacterial and other activities, contributing to medical innovation.
What are the synthesis methods of 3- (difluoromethoxy) bromobenzene?
To prepare 3- (diethylamino) propionitrile, the synthesis method is as follows:
First, it can be obtained by reacting 3-chloropropionitrile with diethylamine. In this reaction, the chlorine atom of 3-chloropropionitrile is quite active and can undergo nucleophilic substitution reaction with the nitrogen atom in diethylamine. Slowly drop 3-chloropropionitrile into a reaction vessel containing diethylamine, and stir the reaction in a suitable temperature and solvent. The commonly used solvents can be ethanol, acetonitrile, etc. The reaction temperature is adjusted according to the specific situation, about 50-80 ℃. After the reaction is completed, the product can be purified by distillation and extraction to obtain 3- (diethylamino) propionitrile.
Second, acrylonitrile and diethylamine are used as raw materials and prepared by addition reaction under the action of catalyst. This reaction uses the active check point of the catalyst to add the carbon-carbon double bond of acrylonitrile to diethylamine. The catalyst used may be a transition metal complex, such as palladium chloride. The reaction is carried out under mild conditions, with a temperature of about 30-60 ° C. The solvent can be selected from toluene, dichloromethane, etc. After the reaction is completed, the target product is obtained after separation and purification.
Third, first react ethylene oxide with diethylamine to obtain diethylaminoethanol, and then react diethylaminoethanol with hydrocyanic acid under specific conditions to produce 3- (diethylamino) propionitrile. When ethylene oxide reacts with diethylamine, ethylene oxide is ring-opened and combined with diethylamine. After the reaction of diethylaminoethanol with hydrocyanic acid, the hydroxyl group is replaced by cyanide. During this process, the reaction conditions need to be carefully controlled to ensure the smooth progress of the reaction and the purity of the product.
What are the physical properties of 3- (difluoromethoxy) bromobenzene?
Di (diethylamino) acetyl chloride, which has special physical and chemical properties. It is a colorless to light yellow transparent liquid and exists at room temperature and pressure. Its boiling point is about a specific value, which is due to the specific structure and intermolecular forces. Looking at its solubility, it can be soluble in many organic solvents, such as ethers, hydrocarbons, etc. Due to the similar miscibility, its molecular structure is compatible with organic solvents.
Furthermore, di (diethylamino) acetyl chloride is chemically active. The chlorine atoms in its molecules are highly active and prone to substitution reactions. When encountering nucleophiles, such as alcohols, amines, etc., chlorine atoms are easily replaced by nucleophilic groups, and then form new compounds. This is because the chlorine atom is affected by the electronic effect of carbonyl and diethylamino, and the electron cloud density changes, making it easier to leave.
Because of its active chemistry, special attention should be paid during storage and use. It should be avoided from contact with reactive substances such as water and alcohols, and should be stored in a cool, dry and well-ventilated place to prevent deterioration and danger. In the field of chemical synthesis, it is often used as an important intermediate to prepare a variety of compounds with special properties, and is one of the key raw materials for organic synthesis.
What is the market price of 3- (difluoromethoxy) bromobenzene?
In today's market, the price of (3- (diethylamino) acetylaniline) has fluctuations due to the general reason.
The shadow of its price, the first is the supply and demand. If above the market, the demand for this product is high, but the supply is limited, it will be low; on the contrary, if the supply is abundant, and the demand is low, there will be a drop.
Furthermore, the cost of raw materials also depends on. (3- (diethylamino) acetylaniline) production, the need for general raw materials, raw materials rising, the cost of its production also increases, and the price is low; raw materials falling, the cost drops, or drops.
The technology of manufacturing, also affects its cost. If the technology is refined, the efficiency of production will increase greatly, and the cost will be reduced, or it will decrease in the market; and if the production model is large, the efficiency of the model will decrease, or it will also decrease. However, if the technology is high, the production will be low, and it will be low.
In addition, policies, decrees, and market regulations are all involved. Policies encourage their effectiveness, or there will be benefits, or there will be a reduction; if the policy is limited, there will be a reduction. The same is strong, and the market will occupy, and the business will be promoted or reduced; on the contrary, if the market is oligopolistic, the price will be fixed and high.
The market of (3- (diethylamino) acetylaniline) is determined by the interaction of supply and demand, raw materials, technology, policies, and other factors.
What are the precautions for 3- (difluoromethoxy) bromobenzene during storage and transportation?
Di (diethylamino) ethyl ether, that is, 3 - (diethylamino) ethyl ether, this material should be paid attention to when storing and transporting.
First, because of its flammability, it is very easy to burn in case of open flames and hot topics. Therefore, the storage place must be kept away from fire and heat sources, and should be placed in a cool and ventilated place. The temperature of the warehouse should be controlled within a reasonable range to prevent danger caused by excessive temperature. During transportation, the transportation vehicle must also avoid fire sources and high temperature areas, and drive carefully to avoid open flames caused by collision and friction, which will ignite the substance.
Second, this substance is harmful to human health. Its vapor or fog can irritate the eyes and upper respiratory tract, and high concentration inhalation can cause anesthesia and even endanger life. When storing, the warehouse should be equipped with corresponding leakage emergency treatment equipment and suitable containment materials to prevent injuries to personnel during leakage. When transporting, transporters must take protective measures, such as wearing gas masks, wearing protective clothing, etc., to ensure their own safety.
Third, di (diethylamino) ethyl ether is a dangerous chemical, and strict regulations and standards must be followed for storage and transportation. When storing, it is necessary to register and record according to regulations, and clarify the storage quantity, location and other information. When transporting, it is necessary to have corresponding transportation qualifications. Warning signs should be hung on transportation vehicles, and transportation routes should be planned in advance to avoid sensitive areas such as densely populated areas and water source protection areas.
Fourth, this substance also has potential harm to the environment. If a leak occurs, it will not only pollute the soil and water sources, but also may cause damage to the surrounding ecological environment. Therefore, anti-leakage measures should be taken in the storage area, such as setting up cofferdams. During transportation, if a leak unfortunately occurs, emergency measures should be taken immediately to prevent the spread of pollution, clean up the leak in time, and properly dispose of the contaminated soil and water.