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3-Chloro-4-Iodofluorobenzene

3-Chloro-4-Iodofluorobenzene

Hongda Chemical

Specifications

HS Code

487010

Chemical Formula C6H3ClFI
Appearance Liquid (expected, based on similar haloarenes)
Boiling Point No common data, but likely high due to halogen substitution
Melting Point No common data, influenced by halogen - induced intermolecular forces
Density No common data, but heavier than water due to halogens
Solubility In Water Low (non - polar nature due to aromatic ring and halogens)
Solubility In Organic Solvents Good (in non - polar or moderately polar solvents like benzene, dichloromethane)
Vapor Pressure Low (due to relatively high molecular weight and intermolecular forces)
Stability Stable under normal conditions, but reactive towards strong nucleophiles and reducing agents

As an accredited 3-Chloro-4-Iodofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - chloro - 4 - iodofluorobenzene packaged in a sealed glass bottle.
Storage 3 - Chloro - 4 - iodofluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass. Label the container clearly to prevent misidentification and ensure compliance with safety regulations.
Shipping 3 - Chloro - 4 - iodofluorobenzene is a chemical. For shipping, it must be in a well - sealed, corrosion - resistant container. It should be transported in accordance with hazardous chemical regulations, ensuring proper labeling and safety precautions during transit.
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3-Chloro-4-Iodofluorobenzene 3-Chloro-4-Iodofluorobenzene
General Information
Historical Development
Fu 3 - Chloro - 4 - Iodofluorobenzene is also an organic compound. Its research and development process began with the study of halogenated aromatics by various scholars. In the past, organic chemistry was just emerging, and many scholars explored new substances, hoping to expand the boundaries of chemistry.
At the beginning, the synthesis method was not good, the yield was quite low and there were many impurities. However, the public continued to work hard over the years to improve the technology. Or optimize the reaction conditions, or find a suitable catalyst. Finally, a good method can be obtained to produce this compound.
Its application is also becoming more and more widespread, contributing to the fields of medicine and materials. In medicine, it may be a key intermediate for the synthesis of new drugs; in the material industry, it may assist in the development of new materials to meet various needs. The historical evolution of this compound relies on wisdom and diligence, which contribute to the prosperity of chemistry.
Product Overview
3-Chloro-4-iodofluorobenzene is also an organic compound. Its color may be colorless to light yellow liquid, with a special odor. In the molecular structure, above the benzene ring, the chlorine atom occupies the third position, and the iodine atom and the fluorine atom are separated from the fourth position. This unique arrangement gives it specific chemical properties.
The preparation method often relies on the technique of organic synthesis. It can be prepared after several steps of reaction and careful regulation of conditions. It has a wide range of uses in the field of organic synthesis and can be used as a key intermediate to participate in the construction of many complex organic compounds. Due to the presence of halogen atoms, it has considerable chemical activity and can react with a variety of reagents, such as substitution and addition. It is favored by organic synthesis chemists and has potential application value in drug development, materials science, and other fields. It is an indispensable substance in organic chemistry research.
Physical & Chemical Properties
3-Chloro-4-iodine fluorobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, or in a liquid state, it has a special odor. The genera of its boiling point and melting point are related to its use and preservation. The boiling point is related to the temperature of its gasification, and the melting point is determined when its solid-liquid transformation.
On its chemical properties, the atoms of chlorine, iodine and fluorine are on the benzene ring, which makes the substance have unique reactivity. The stability of the benzene ring interacts with the activity of the halogen atom. It can react with nucleophiles, and the halogen atom is easily replaced by other groups. This is because the halogen atom has electron absorption, which causes the electron cloud density of the benzene ring to change. And because of its fluorine atom, the compound has unique performance in specific reactions, or increases its stability, or changes its reaction path. Studying the physical and chemical properties of this compound can provide the most important basis for its synthesis and application.
Technical Specifications & Labeling
Today there is a thing called 3 - Chloro - 4 - Iodofluorobenzene. Its technical specifications and identification (product parameters), we need to study in detail.
On its technical specifications, the choice of raw materials, when the refined selection of pure, impurities must be fine. The method of synthesis must follow the precise process, temperature, pressure, time and other factors should be appropriate. Each step needs to be carefully controlled to prevent poor pools and lead to changes in quality.
As for the identification (product parameters), when it is clear that its chemical conformation, purity geometry, melting point, density, etc., all need to be detailed in the book. In this way, it can be fully exposed to the user, and people can make good use of it according to its parameters to achieve the desired effect without the risk of misuse.
Preparation Method
If you want to make 3-chloro-4-iodine fluorobenzene now, you should study the preparation method in detail. The selection of raw materials is appropriate for suitable compounds containing fluorine, chlorine and iodine. The preparation process can first make fluorine-containing and chlorine-containing aromatic hydrocarbons react under specific conditions to introduce chlorine atoms. This reaction requires precise temperature control and the selection of a suitable catalyst to promote the smooth reaction.
Then, iodine atoms are introduced. This step selects mild reaction conditions to avoid excessive reaction and lead to by-products clumping. Between reaction steps, the intermediate must be properly handled to ensure the purity of the product.
As for the activation mechanism, the reaction activation energy can be reduced by the electronic interaction between the catalyst and the reactants. At the same time, regulating the pH of the reaction system can also effectively affect the reactivity. In this way, 3-chloro-4-iodofluorobenzene can be efficiently prepared, which lays the foundation for subsequent research and application.
Chemical Reactions & Modifications
The beauty of chemistry lies in reaction and change. Now on this compound of 3 - Chloro - 4 - Iodofluorobenzene, its reaction is changeable and its properties are different.
Its chemical reaction often depends on the change of conditions. Temperature, solvent, catalyst, are all about. In case of a certain reagent, or a change in substitution, the halogen atom translocates, and a new product is born. At suitable temperature and pressure, its structure or rearrangement, and the change of conformation affect the performance.
As for changing its properties, it can be modified by chemistry. The addition of a group to the benzene ring, which regulates the distribution of electron clouds, changes its activity and polarity. Or the conjugation system, so that the spectral characteristics are different from before.
can also be mixed with other substances by physical means to form a complex, and the properties are also changed. The way of chemistry explores the reaction and change of this compound in order to achieve the wonders of use and benefit many fields.
Synonyms & Product Names
3-Chloro-4-iodine fluorobenzene is also a new product of the chemical. Although its name is the same, the name of the assimilate and the trade name are diverse.
Looking at this thing today, in the academic world, there are also different names. Or because of its different structure, or because of the focus of research, the names of all assimilates appear. And the business names, the merchants also have their own ingenuity in order to recognize their characteristics.
Gu Yun: "The name is the real guest." Although the names are different, the quality of 3-chloro-4-iodine fluorobenzene remains unchanged. The names and commercial names of all kinds of assimilated substances are all ways to express their nature and use them. Scholars want to clarify their details, and they should investigate their quality and nature, so as not to be confused by the variety of names.
Safety & Operational Standards
Safety and Handling Specifications for 3-Chloro-4-Iodofluorobenzene
For 3-chloro-4-iodofluorobenzene, chemical substances are also used. Its preparation, storage and use should strictly abide by safety and operating standards, so as to ensure that everything goes smoothly and does not harm people and the environment.
When preparing, all raw materials and reagents must be accurately weighed and properly mixed. And the temperature, pressure and time of the reaction are all key factors and must be carefully regulated. Experimenters should be in front of protective equipment, such as goggles, gloves, protective clothing, etc., to prevent material spillage and damage to the body. The reaction device should also be stable and safe, and all kinds of instruments should be checked in advance to ensure their normal operation.
As for storage, 3-chloro-4-iodofluorobenzene should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent it from being decomposed by heat or causing fire. Do not store with oxidizers, reducing agents and other reactive substances to avoid accidents. Storage containers must be tightly sealed to prevent leakage. And when posted with clear signs indicating their name, nature and hazards.
When using, the operation should be carried out in the fume hood to drain volatile gas. Use the appropriate amount, do not waste, and avoid excessive risk. If you accidentally come into contact with the skin or eyes, rinse with plenty of water immediately and seek medical treatment if necessary. After using the utensils, you need to wash them in time, properly dispose of the residual materials, and do not discard them at will to avoid polluting the environment.
All matters involving 3-chloro-4-iodofluorobenzene should be based on safety and follow the established operating norms. In this way, you can move forward steadily in the process of chemical research and production without any worries.
Application Area
Today there is a substance called 3 - Chloro - 4 - Iodofluorobenzene. The application field of this substance is quite wide. In the field of medicinal chemistry, it is the key raw material for the synthesis of special drugs. With its unique chemical structure, it can make a good medicine to resist difficult diseases and save patients from pain.
In the field of materials science, this compound also plays an important role. It can participate in the creation of new functional materials, such as materials with special optical or electrical properties, for the development of electronic devices, optical instruments and other fields.
Furthermore, in the field of organic synthetic chemistry, it is an important building block for the construction of complex organic molecules. Chemists use their delicate reactions to build diverse organic structures, expand the boundaries of organic chemistry, and make unremitting progress for scientific progress.
Research & Development
In recent years, I have dedicated myself to the study of 3 - Chloro - 4 - Iodofluorobenzene in the field of chemistry. Its properties are unique, and it has great potential in the process of organic synthesis.
At the beginning, I explored the method of its preparation, but encountered many twists and turns. The choice of raw materials and the conditions of the reaction all need to be carefully considered. After months of trying, a feasible path was found. With a specific halogenation method, temperature control and speed regulation were used to make the reaction smooth.
Then its reaction characteristics were observed. Among many reagents, choose its adaptor to explore the mechanism of its reaction. It was found that its reaction in nucleophilic substitution exhibited unique activity, paving the way for the synthesis of new compounds.
Looking to the future, we hope to expand its application field based on this. Or used to create new drugs, or to contribute to materials science. I am willing to make unremitting research to promote this compound in the realm of scientific research and industry, bloom brilliance, and contribute to the development of chemistry.
Toxicity Research
Wenfu 3 - Chloro - 4 - Iodofluorobenzene is also studied by chemists of our generation. The study of its toxicity is quite important.
The structure of its molecules was initially observed, and the atoms of chlorine, iodine and fluorine were attached to the benzene ring. The properties of these atoms may lead to changes in toxicity. The benzene ring has a certain chemical activity, and it adds halogen atoms, so its role in biological systems cannot be underestimated.
For the purpose of studying toxicity, use various methods to test it. Observe its shadow on cells, and observe how the growth and metabolism of cells are different. Also take animals as models to explore the changes in visceral functions after entering the body.
After various investigations, it can be found that 3-Chloro-4-Iodofluorobenzene may have certain toxicity. It may disturb the normal physiology of cells and cause cell damage. In animals, it may affect the health of the body, such as liver and kidney. However, in order to clarify its toxicity, it needs to be further studied to explore the details of its toxicology, so as to provide solid evidence for protection and application.
Future Prospects
Fu 3 - Chloro - 4 - Iodofluorobenzene, in today's chemical research, has made its head stand out. Looking at the structure of its molecules, the atoms of chlorine, iodine and fluorine are cleverly combined, and there are endless possibilities.
Looking to the future, it can be used in medical creation, or it can become a powerful tool for curing diseases. With its unique chemistry, it can accurately interact with pathogenic molecules, paving the way for the birth of new drugs. In the field of material research and development, it is also expected to bring out its brilliance. Or it can give material specificity, such as excellent conductivity and optics, leading the trend of material change.
Furthermore, it is in the catalytic reaction, or a key catalyst, to accelerate the reaction process and improve the yield. Although there may be thorns in the road ahead, the researchers are ambitious and unremitting. With wisdom and sweat, we hope to uncover its mystery and expand its application, so that 3 - Chloro - 4 - Iodofluorobenzene will shine in the future and contribute to human well-being.
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Frequently Asked Questions

As a leading 3-Chloro-4-Iodofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 3-Chloro-4-Iodofluorobenzene?
3-Chloro-4-iodine fluorobenzene is also an organic compound. It is active and has special performance in chemical reactions.
In this substance, the atoms of chlorine, iodine and fluorine have their own characteristics, which makes their chemical properties interesting. Fluorine atoms have strong electronegativity, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. However, its adjacent and para-sites are affected by fluorine atoms, and the electron cloud density is relatively high. Under specific conditions, electrophilic reagents may attack.
Chlorine atoms also affect the distribution of molecular electron clouds, and cooperate with fluorine atoms to influence the reaction path. Although the iodine atom is relatively large, its polarizability is strong, and it may play a unique role in some reactions, such as participating in nucleophilic substitution, iodine ions are easier to leave, so that the reaction can proceed.
3-chloro-4-iodofluorobenzene has attracted much attention in the field of organic synthesis, and can be used as a key intermediate. It can be converted into other organic compounds through many reactions, such as palladium-catalyzed coupling reaction, which interacts with alkenyl groups, aryl groups and other reagents to form carbon-carbon bonds. Organic molecules with complex structures and diverse functions can be derived, which have potential applications in drug research and development, materials science and many other fields.
What are the main uses of 3-Chloro-4-Iodofluorobenzene?
3-Chloro-4-iodofluorobenzene is an important compound in the field of organic synthesis. It has a wide range of uses and is now detailed by you.
First, in the field of medicinal chemistry, this compound is often a key intermediate. In the synthesis path of many drugs, 3-chloro-4-iodofluorobenzene can introduce specific functional groups through various chemical reactions, and then construct molecular structures with specific biological activities. For example, when developing targeted drugs for certain diseases, by skillfully using its structural properties, it can precisely regulate the interaction between the drug and the target, enhance the efficacy of the drug, and reduce side effects. It is an indispensable raw material in the process of creating new drugs.
Second, in the field of materials science, 3-chloro-4-iodofluorobenzene also has important uses. When synthesizing new organic optoelectronic materials, it can be integrated into polymer systems as a structural unit. Due to its unique electronic effect and spatial structure, it can effectively adjust the photoelectric properties of materials, such as improving the conductivity and fluorescence efficiency of materials, and then be applied to the manufacture of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices, promoting the progress and development of materials science.
Third, in pesticide chemistry, 3-chloro-4-iodofluorobenzene can be used to synthesize high-efficiency and low-toxicity pesticides. By chemically modifying it, pesticide products with high selective inhibition or killing effect on specific pests or pathogens can be prepared, providing powerful chemical tools for agricultural pest control and ensuring crop yield and quality.
In summary, 3-chloro-4-iodofluorobenzene plays a key role in many fields such as medicine, materials, pesticides, etc., and has a non-negligible role in promoting the development of related industries.
What is 3-Chloro-4-Iodofluorobenzene synthesis method?
The synthesis of 3-chloro-4-iodofluorobenzene is an important topic in the field of organic synthesis. To make this compound, several common chemical pathways can be followed.
One is to start with fluorobenzene derivatives. First, chlorination occurs at specific positions on the benzene ring under specific reaction conditions with an appropriate halogenating agent, such as chlorine gas. This step requires careful regulation of the reaction temperature, reaction time, and the proportion of the reactants before the chlorine atom can precisely replace the corresponding hydrogen atom on the benzene ring to obtain a chlorine-containing fluorobenzene derivative.
Then, the obtained chlorofluorobenzene derivative is iodized with an iodine source, such as potassium iodide, in the presence of a catalyst. Commonly used catalysts, such as copper salt catalysts, can effectively promote this reaction. During the reaction, the choice of solvent is also crucial. It is necessary to select a solvent that can dissolve the reactants and has no adverse effect on the reaction, such as some polar organic solvents. By this step of the reaction, the iodine atom can replace the hydrogen atom at another specific position on the benzene ring, thereby generating the target product 3-chloro-4-iodofluorobenzene.
Another feasible method is to start from other more complex aromatic compounds and achieve it through a series of functional group conversion reactions. For example, aromatic compounds with suitable substituents are prepared first, and then these substituents are gradually modified and converted, followed by the introduction of chlorine atoms, iodine atoms and fluorine atoms. Although this path is more complex, it is also an effective strategy under the limitations of certain raw material availability and reaction conditions. During the whole synthesis process, each step of the reaction requires precise separation and purification of the product. Common methods include distillation, recrystallization, column chromatography, etc., to ensure the purity and quality of the final 3-chloro-4-iodofluorobenzene.
3-Chloro-4-Iodofluorobenzene What are the precautions during storage and transportation?
3-Chloro-4-iodofluorobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to.
First words storage. This compound should be stored in a cool, dry and well-ventilated place. Cover a high temperature and humid place due to its nature or affected by temperature and humidity, which may cause chemical reactions and damage its quality. Furthermore, keep away from fire and heat sources, which are all flammable dangerous factors. If exposed, or cause a fire, it will endanger safety. It should be stored separately from oxidizing agents, acids, alkalis, etc. Because of its active chemical properties, mixed with various substances, it is prone to chemical reactions and accidental changes.
Times and transportation. During transportation, the packaging must be sturdy to prevent damage and leakage. The packaging materials selected should have good corrosion resistance and sealing properties to ensure that the material is not disturbed by the external environment. Transportation vehicles need to be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment, just in case. During transportation, follow the specified route and do not stop in densely populated areas and residential areas, in order to avoid its leakage from causing harm to the public. During transportation, escorts must pay close attention to the condition of the goods. If there is any abnormality, they should be disposed of in time. When loading and unloading, they should also be handled lightly to avoid violent impact and vibration, resulting in package damage and material leakage.
In short, the storage and transportation of 3-chloro-4-iodofluorobenzene are all about safety and quality, and must be treated with caution and follow relevant procedures to ensure safety.
3-Chloro-4-Iodofluorobenzene impact on the environment and human health
3-Chloro-4-iodofluorobenzene is an organic compound. It has implications for both the environment and human health, as detailed below.
First talk about its impact on the environment. This compound has certain chemical stability and is difficult to degrade rapidly through natural processes. If released into the environment, or persists in soil or water bodies. In soil, it may cause soil pollution, preventing plant roots from absorbing nutrients and water, affecting plant growth and development, and damaging vegetation coverage and biodiversity. In water bodies, it can cause water quality to deteriorate and poison aquatic organisms. If aquatic organisms are exposed to this substance for a long time, there may be abnormal growth, reproduction suppression, or even death. In the long run, it may cause imbalance in the aquatic ecosystem, damage the food chain, and affect the stability and function of the entire ecosystem.
Describe its harm to human health. Inhalation through the respiratory tract, skin contact or accidental ingestion can enter the human body. Inhalation of this substance vapor may irritate the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Long-term inhalation may damage lung function and increase the risk of respiratory diseases. If skin contact, it may cause skin allergies, redness, and itching. If it penetrates the skin into the blood circulation, it may damage important organs such as the liver and kidneys. Accidentally ingesting this compound can cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, diarrhea, etc. It may interfere with normal physiological metabolism in the body, damage the nervous system, cause headache, dizziness, fatigue, insomnia and other symptoms. Long-term exposure or ingestion is more likely to be teratogenic and carcinogenic, and seriously threaten human health.
In summary, 3-chloro-4-iodofluorobenzene has potential hazards to the environment and personal health. When producing, using and handling, it should be done with caution to prevent its escape from causing environmental pollution and personal damage.