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3-Chloro-4-Fluoronitrobenzene

3-Chloro-4-Fluoronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    108601

    Chemical Formula C6H3ClFNO2
    Molar Mass 177.545 g/mol
    Appearance Yellow to light - brown solid
    Melting Point 28 - 32 °C
    Boiling Point 242 - 243 °C
    Density 1.486 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 106 °C
    Vapor Pressure Low at room temperature
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 3-Chloro-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3 - chloro - 4 - fluoronitrobenzene packaged in a sealed, chemical - resistant bottle.
    Storage 3 - Chloro - 4 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent leakage and vapor release. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential chemical reactions.
    Shipping 3 - Chloro - 4 - fluoronitrobenzene is a chemical. Ship it in tightly sealed, corrosion - resistant containers. Follow all hazardous materials shipping regulations, ensuring proper labeling for safe and compliant transportation.
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    3-Chloro-4-Fluoronitrobenzene 3-Chloro-4-Fluoronitrobenzene
    General Information
    Historical Development
    3-Chloro-4-fluoronitrobenzene is also an organic compound. At the beginning, chemists explored and tried various substances to obtain this product. At the beginning, the preparation method was simple and crude, the yield was meager, and the quality was difficult to achieve.
    However, with the passage of time and the advancement of science and technology, the preparation techniques have become increasingly refined. All reaction conditions can be fine-tuned, and the choice of catalysts is more accurate. The yield increases, and the purity is higher. The use of this compound in the fields of medicine and pesticides has gradually increased, adding to the progress of the industry. The difficulties of preparation in the past have now turned into a smooth road. Looking forward to the future, it may bloom in more new fields and promote the chemical industry to a higher level.
    Product Overview
    3-Chloro-4-fluoronitrobenzene
    Fu 3-chloro-4-fluoronitrobenzene is an important raw material for organic synthesis. Its shape is light yellow to yellow crystalline powder, with unique physical and chemical properties.
    Looking at its physical properties, the melting point is suitable, and it is a stable solid state in a specific temperature range. This property makes it easier to maintain its shape during storage and transportation.
    Discussing chemical properties, because it contains chlorine, fluorine, nitro and other functional groups, the activity is significant. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes nucleophilic substitution more likely. The presence of chlorine and fluorine atoms also affects the reactivity and selectivity of molecules.
    is often used as a key intermediate in the field of organic synthesis. It can be derived from many high-value organic compounds through nucleophilic substitution, reduction and other reactions. It is widely used in medicine, pesticides, dyes and other industries. It is an indispensable substance for chemical research.
    Physical & Chemical Properties
    3-Chloro-4-fluoronitrobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is in a solid state, colored or light yellow, with a special odor. The melting point is quite fixed, about [X] ° C. This characteristic can be used as an important basis for separation and identification. The boiling point is also fixed, about [X] ° C, indicating the energy required for its gasification.
    In terms of its chemical properties, because it contains chlorine, fluorine, nitro and other functional groups, the chemical activity is quite strong. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, so the electrophilic substitution reaction is difficult to occur, but the nucleophilic substitution reaction is easy to proceed. Chlorine and fluorine atoms, due to their electronegativity differences, also affect molecular reactivity and selectivity. And under specific conditions, they can participate in many chemical reactions, such as reduction reactions, substitution reactions, etc., and are widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    There is now a product named 3-chloro-4-fluoronitrobenzene. Its process specifications and identification (product parameters) are crucial to the quality and use of this product.
    Process specifications, selected from the raw materials, must be pure and free of impurities, suitable for specific standards. The preparation method requires controlling temperature and pressure variables. If the reaction time, the temperature should be stable in a certain range. If it is too high, the product will be variable, and if it is too low, the reaction will be slow. The pressure must also be consistent, so that the reaction can be smooth and high-purity products can be obtained.
    In terms of identification (product parameters), the geometric content is indicated, the number of impurities is indicated, and the appearance color and shape are fixed. This is the basis for judging the pros and cons of the product. With precise process specifications and clear identification (product parameters), high-quality 3-chloro-4-fluoronitrobenzene can be obtained to meet the needs of all parties.
    Preparation Method
    3-Chloro-4-fluoronitrobenzene is also an organic compound. The method of its preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
    To make this product, the commonly used raw materials are specific halogenated aromatics, etc. The first reaction conditions of the production process are controlled, and the raw materials are reduced according to specific reaction steps under suitable temperature and pressure.
    The reaction step is to first combine halogenated aromatics with reagents containing fluorine, chlorine and nitro groups under the action of a catalyst. The choice of catalyst is very important, which can promote the rapid progress of the reaction and increase the rate of yield. If a certain metal salt is selected as the catalyst, the reactant molecules can be activated and the energy barrier of the reaction can be reduced.
    When reacting, it is necessary to pay attention to the temperature. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow. After the reaction is completed, pure 3-chloro-4-fluoronitrobenzene will be obtained through separation and purification. This preparation method depends on precise operation and suitable conditions to achieve its work.
    Chemical Reactions & Modifications
    3-Chloro-4-fluoronitrobenzene is an organic compound. Its chemical reaction is related to the improvement of chemical properties, which is a key issue for our chemical researchers.
    In the past, we have often encountered obstacles in exploring the reaction of this compound. The reaction conditions are harsh and the yield is not ideal. However, we have worked tirelessly to improve.
    After repeated experiments, it has been found that adjusting the temperature and solvent of the reaction, together with a suitable catalyst, can promote the rate of reaction and increase its yield. And the selectivity of the reaction can also be optimized to make the product purer.
    As for the performance improvement, after modification, its stability is improved, and it is more convenient to apply in many fields. This is the result of our research, and we hope to contribute to the development of chemistry and industrial production.
    Synonyms & Product Names
    3-Chloro-4-fluoronitrobenzene is also a chemical product. Its synonymous name and the name of the product are quite important.
    Cover the name of the synonym, which can help people in the academic community to accurately reach the idea during the discussion and exchange, without ambiguity. The name of the product is related to the circulation of the market, and the merchant uses it to identify the product, so that consumers can understand its characteristics.
    3-chloro-4-fluoronitrobenzene, or other names, all refer to this thing. Such synonymous names, or according to the characteristics of their chemical structure, or follow the convention of naming in the past. As for the name of the product, merchants go out of their way to recognize its characteristics, advantages, or to meet the needs of the market.
    From this perspective, the synonymous name of 3-chloro-4-fluoronitrobenzene and the name of the product are of great significance in the research and trade of chemical products.
    Safety & Operational Standards
    3-Chloro-4-fluoronitrobenzene is also a chemical substance. In the process of its experiment and production, safety and operating standards are of paramount importance, which is related to personal safety and the quality of results.
    To make this 3-chloro-4-fluoronitrobenzene, it must be done in a well-ventilated place. Because of its certain toxicity and irritation, if it is blocked in an occluded place, harmful gases will accumulate, which will endanger the health of the operator. And the laboratory should be equipped with perfect ventilation equipment, so that the air is always fresh and harmful gases can disperse quickly.
    When operating, protective equipment is indispensable. When the operator wears protective clothing, its quality is tough and can resist the erosion of chemical substances; when wearing protective gloves, it must be made of chemical corrosion-resistant materials to prevent the hands from touching poisons; protective glasses are also required to prevent liquid from splashing into the eyes and causing damage to the eyes.
    There are also regulations for the handling of materials. When using 3-chloro-4-fluoronitrobenzene raw materials, the action should be slow and stable, and do not spill. If there is any accidental spill, clean it up immediately and dispose of it in accordance with relevant regulations. Do not dispose of it at will to avoid polluting the environment.
    When heating the reaction, temperature control is crucial. It is necessary to use a precise temperature control device according to the established process to slowly heat up and pay close attention to the reaction process. If it is overheated, the reaction will be out of control or dangerous; if it is too cold, the reaction will be slow, which will affect the yield.
    After the reaction is completed, the handling of the product should also be cautious. Either purification or separation should be carried out according to the specifications. The remaining waste should not be dumped indiscriminately. When it is collected by classification, it should be handed over to professional institutions for proper disposal.
    Only by strictly observing safety and operating standards can the research and development of 3-chloro-4-fluoronitrobenzene be smooth, ensuring the safety of personnel, protecting the cleanliness of the environment, and promoting the excellence of the fruit.
    Application Area
    3-Chloro-4-fluoronitrobenzene is also a chemical product. It is widely used and involves various fields. In the field of medicine, it can be used as a raw material to make various medicines and treat human diseases. In the field of agriculture and planting, it can be used as a pesticide material, to control insects and protect seedlings, and to ensure the abundance of crops. In the industry of pigments, it helps to form colorful colors, ornaments, and a beautiful view of the world. These applications are all due to the specific properties of 3-chloro-4-fluoronitrobenzene, which can be combined with other things and become useful things. Therefore, in this world's industry, agriculture, medicine, etc., are all indispensable, and have great contributions to helping the world advance and people's livelihood.
    Research & Development
    Today there is a product called 3-chloro-4-fluoronitrobenzene. As a chemical researcher, I am very concerned about the research and development of this product.
    This 3-chloro-4-fluoronitrobenzene has unique properties and has great potential in many fields of chemical industry. We have devoted ourselves to studying its structural characteristics and exploring the best method of synthesis, hoping to improve the yield and optimize the quality.
    During the research process, the influence of reaction conditions, temperature, pressure, catalyst and other factors were carefully studied. After repeated experiments, some gains were made, and the synthesis method gradually matured.
    Looking forward to its development, it may shine in the pharmaceutical, materials and other industries. We should make unremitting efforts to tap its potential, promote the wide application of this compound, and contribute to the progress of the chemical field, so that it will bloom in the future development.
    Toxicity Research
    3-Chloro-4-fluoronitrobenzene is also a chemical substance. It is crucial for toxicological research. Today, its toxicity is carefully investigated to clarify its properties.
    Looking at this substance, its molecular structure is unique, chlorine, fluorine and nitro coexist. Chlorine is very active, fluorine has strong electronegativity, and nitro groups also have special chemical activity. The three coalesce, or cause toxicological changes.
    After experimental investigation, it may have multiple effects on organisms. Or damage the structure and function of cells, and disturb biochemical reactions. In animal experiments, it was found that after ingesting this substance, the physiological function appeared abnormal. Organs may be damaged by it, and the metabolic pathway may be disrupted.
    However, in order to fully understand its toxicity, many studies are needed. It involves a wide range of different organisms, explores the effects of various doses, and analyzes the toxicological mechanism in detail. In this way, the toxicity of 3-chloro-4-fluoronitrobenzene can be fully understood, providing a solid foundation for protection and application.
    Future Prospects
    Today, there is a product named 3-chloro-4-fluoronitrobenzene. Our generation is a chemical researcher. When we look at this substance, we think about its future development, and our hearts are full of excitement.
    This compound has unique properties and has promising properties in various fields of chemical industry. In the way of pharmaceutical synthesis, it may be the basis for new agents to cure various diseases and save people from diseases. In the process of material creation, it is also expected to become a new type of material, which will help the development of science and technology, and make the equipment exquisite and effective.
    We should study it diligently, explore its subtleties, and develop its potential. With time, this 3-chloro-4-fluoronitrobenzene will be able to shine in the future. Make the world benefit from it, and technology will advance accordingly. This is the ambition of our generation of chemical researchers, and it is also the prospect of future development.
    Where to Buy 3-Chloro-4-Fluoronitrobenzene in China?
    As a trusted 3-Chloro-4-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Chloro-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Chloro-4-Fluoronitrobenzene?
    3-Chloro-4-fluoronitrobenzene is a crucial intermediate in organic synthesis and is widely used in many fields.
    First, in the field of pharmaceutical synthesis, its role is crucial. The preparation of many drugs relies on it as a starting material. Taking some antibacterial drugs as an example, 3-chloro-4-fluoronitrobenzene can be replaced by chlorine atoms or fluorine atoms through specific chemical reactions, such as nucleophilic substitution reactions, which can replace its chlorine atoms or fluorine atoms with groups with specific physiological activities, and then construct a drug molecular structure with antibacterial activity. This process is like a skilled craftsman using it as a cornerstone to carefully carve a good medicine for healing and saving people.
    Second, in the synthesis of pesticides, it also plays a key role. The creation of pesticides requires precise molecular design and synthesis. 3-Chloro-4-fluoronitrobenzene can participate in the construction of many pesticide molecules due to its unique chemical structure. By introducing different functional groups, pesticides can be endowed with specific biological activities such as insecticides and herbicides. For example, in the synthesis of some efficient herbicides, 3-chloro-4-fluoronitrobenzene is an indispensable basic raw material. After a series of chemical reactions, it eventually becomes a powerful tool to protect farmland.
    Furthermore, in the field of materials science, it also has applications. In the preparation of some high-performance polymer materials, 3-chloro-4-fluoronitrobenzene can participate in the polymerization reaction as a functional monomer. With its special functional groups, it can regulate the properties of polymers, such as improving the heat resistance and mechanical properties of materials. It is like injecting special "energy" into the material to make it have more excellent characteristics to meet the needs of materials in different scenarios.
    In summary, 3-chloro-4-fluoronitrobenzene, with its unique chemical structure, plays an irreplaceable role in the fields of medicine, pesticides, materials science, etc., and has become an important organic compound that promotes the development of various fields.
    What are the physical properties of 3-Chloro-4-Fluoronitrobenzene?
    3-Chloro-4-fluoronitrobenzene is also an organic compound. It has many physical properties, which are described in detail today.
    This substance is in a solid state under normal conditions, depending on its appearance, or a crystalline powder that is off-white to light yellow. Its melting point is about 35-39 ° C. If heated to this temperature range, the substance gradually melts from a solid state to a liquid state. In terms of boiling point, it is about 235-237 ° C. At this temperature, the liquid will vaporize violently and transform into a gaseous state.
    When it comes to solubility, 3-chloro-4-fluoronitrobenzene is extremely difficult to dissolve in water, and it is difficult to form an effective interaction with water molecules due to its molecular structure characteristics. However, in organic solvents, it shows good solubility, and common organic solvents such as dichloromethane, chloroform, and ether can dissolve it. This is because the molecular structure of organic solvents is more compatible with 3-chloro-4-fluoronitrobenzene, and they can be miscible with each other through Van der Waals forces.
    In terms of density, the density of 3-chloro-4-fluoronitrobenzene is greater than that of water. If it is placed in a container with water, it will sink to the bottom of the water. The smell also has characteristics, although it is not strong and pungent, it also has a special organic smell, which can be detected when handling this substance.
    In addition, the stability of 3-chloro-4-fluoronitrobenzene is acceptable, and its chemical structure is not easy to change under normal temperature and pressure and without special chemical reagents. However, it should be noted that because it contains nitro groups, chlorine atoms and fluorine atoms, it may react chemically when exposed to strong oxidants, strong bases, strong acids and other chemicals, so it must be stored and used in accordance with chemical specifications to ensure safety.
    What are the chemical properties of 3-Chloro-4-Fluoronitrobenzene?
    3-Chloro-4-fluoronitrobenzene is one of the organic compounds. It has unique chemical properties and is widely used in the field of organic synthesis.
    The chemical properties of this compound bear the brunt of its substitution activity. Due to the presence of chlorine, fluorine and nitro groups on the benzene ring, the nitro group has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes nucleophilic substitution easy to occur. Although both chlorine and fluorine are halogen atoms, the radius of the fluorine atom is small and the C-F bond energy is large. When nucleophilic substitution occurs, the chlorine atom is relatively easy to be replaced. If it reacts with nucleophiles such as sodium alcohols and amines, chlorine atoms can be replaced by corresponding groups to form a series of derivatives, which is crucial for the preparation of various nitrogenous and oxygen-containing organic compounds.
    Furthermore, it can participate in the reduction reaction. Nitro groups can be converted into amino groups by reduction means, such as catalytic hydrogenation, ferric acid reduction, etc., to obtain 3-chloro-4-fluoroaniline, which is an important organic synthesis intermediate and has many uses in dyes, medicine and other industries.
    Because of the presence of halogen atoms and nitro groups in its molecules, halogenation reactions and nitrification reactions can occur. However, due to the presence of nitro and halogen atoms occupying specific positions in the benzene ring, the localization effect of subsequent reactions needs to be considered in detail. The newly introduced groups are mostly affected by the dual effects of the electronic effect and the space effect of the existing groups, and the reaction check point has a certain selectivity.
    In addition, 3-chloro-4-fluoronitrobenzene has a certain solubility in common organic solvents such as ethanol, acetone, dichloromethane, etc. This solubility facilitates its participation in various solution-phase chemical reactions, and also plays an important role in its separation and purification process. Its chemical stability is acceptable at room temperature and pressure, but under extreme conditions such as strong oxidants, reducing agents or high temperatures, it is easy to undergo chemical reactions and cause structural changes.
    What is 3-Chloro-4-Fluoronitrobenzene production method?
    There are two common methods for preparing 3-chloro-4-fluoronitrobenzene. The first is to use 4-fluoronitrobenzene as the starting material and obtain it through chlorination. In this process, an appropriate chlorinating agent, such as chlorine gas or chlorine-containing compounds, is used under suitable reaction conditions. Usually, a suitable catalyst, such as an iron-based or aluminum-based catalyst, needs to be selected at a certain temperature and pressure environment to fully react with 4-fluoronitrobenzene. Temperature control is critical. If it is too low, the reaction will be slow, and if it is too high, side reactions will easily occur. Generally speaking, the reaction temperature is maintained between tens of degrees Celsius and 100 degrees Celsius, and the pressure depends on the specific situation. It can be normal pressure or slightly pressurized. Through this chlorination step, chlorine atoms can be introduced at specific positions in the benzene ring of 4-fluoronitrobenzene to obtain 3-chloro-4-fluoronitrobenzene.
    The second method is to use 3-chloro-4-fluoroaniline as the starting material and prepare it by diazotization and nitrification. First, 3-chloro-4-fluoroaniline is diazotized to form diazonium salts with sodium nitrite and inorganic acids such as hydrochloric acid or sulfuric acid at low temperatures, usually at 0-5 degrees Celsius. Subsequently, the diazonium salt is reacted with an appropriate nitrifying agent, such as nitric acid or nitrate, under specific conditions to complete the nitrification process and obtain 3-chloro-4-fluoronitrobenzene. In this route, the diazotization reaction needs to be strictly controlled at temperature to prevent the decomposition of diazonium salts. The nitrification reaction also needs to pay attention to the reaction conditions, such as the proportion of reagents, reaction time, etc., to ensure the yield and purity of the target product. In short, the methods for preparing 3-chloro-4-fluoronitrobenzene have their own characteristics. In actual production, the selection needs to be comprehensively considered according to factors such as raw material availability, cost, and product requirements.
    What 3-Chloro-4-Fluoronitrobenzene need to pay attention to when storing and transporting
    3-Chloro-4-fluoronitrobenzene is also an organic compound. When storing and transporting, it is necessary to pay more attention to ensure safety.
    When storing, the first choice of environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its flammability, it may cause combustion and explosion in case of open flames and hot topics. The temperature of the warehouse should be controlled within a suitable range, and it must not be too high to prevent its stability from being disturbed.
    Furthermore, it should be stored separately from oxidants and edible chemicals. When this compound encounters an oxidizing agent, it is easy to cause a violent chemical reaction, and when it is in the same place as edible chemicals, it may cause pollution and endanger human health.
    Packaging must also be rigorous. Make sure that the packaging is intact and free from leakage. If the packaging is damaged, its escape can cause environmental pollution and pose a hazard to surrounding personnel.
    When transporting, there are also many key points. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers must drive carefully to avoid violent actions such as sudden braking and sharp turns to prevent material leakage due to damaged packaging.
    During transportation, it is strictly forbidden to mix with other contraband substances. And the transportation route should avoid sensitive areas such as densely populated areas and water sources. If a leak unfortunately occurs, immediate and effective measures should be taken to evacuate the surrounding people and prevent the accident from expanding.
    All of these are for the storage and transportation of 3-chloro-4-fluoronitrobenzene. Be careful not to take it lightly, so as not to cause a disaster.