Hongda Chemical
Products
Home  /  Products  / 

3-Chloro-4-Fluorobenzene Bromide

3-Chloro-4-Fluorobenzene Bromide

Hongda Chemical

    Specifications

    HS Code

    886202

    Chemical Formula C6H3BrClF
    Appearance Solid (usually white or off - white)
    Melting Point Typically in a certain range, e.g., 30 - 35°C (approximate, actual may vary)
    Boiling Point Around 210 - 220°C (approximate, depends on conditions)
    Density Approximately [X] g/cm³ (specific value depends on conditions)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
    Flash Point Relatively high, e.g., [X] °C (approximate)
    Vapor Pressure Low vapor pressure at room temperature

    As an accredited 3-Chloro-4-Fluorobenzene Bromide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3 - chloro - 4 - fluorobenzene bromide packaged in a sealed glass bottle.
    Storage 3 - Chloro - 4 - fluorobenzene bromide should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent contact with air and moisture, which could potentially lead to decomposition or unwanted reactions. Store it separately from oxidizing agents and incompatible substances to ensure safety.
    Shipping 3 - Chloro - 4 - fluorobenzene bromide is a chemical. For shipping, it must be properly packaged in accordance with hazardous material regulations. Label containers clearly, and ensure carriers are licensed to transport such chemicals safely.
    Free Quote

    Competitive 3-Chloro-4-Fluorobenzene Bromide prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to sales3@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: sales3@alchemist-chem.com

    3-Chloro-4-Fluorobenzene Bromide 3-Chloro-4-Fluorobenzene Bromide
    General Information
    Historical Development
    The beginning of 3-chloro-4-fluorobromobenzene can be traced back to the process of poor research by chemists. At the beginning, many families gradually came to understand the principle of organic compounds, and thought ingeniously to combine this feature.
    In the past, chemists used fluorine, chlorine and bromine as the basis to find a way to enter the benzene ring. At the beginning, various strategies were tried, but they either encountered obstacles or failed to work. However, chemists persevered, studying the law of reaction in detail, adjusting temperature, controlling quality, and changing the reagents and methods they used.
    After years of research, they found a suitable method. With benzene as the parent, fluorine and chlorine were introduced first, and then bromine was introduced into the site. According to the progress of chemical theory and technology, the reaction was gradually controlled and the yield was also increased.
    Naturally, 3-chloro-4-fluorobromobenzene has been used in the chemical industry more and more widely, or it is a combination of pharmaceutical starting materials or auxiliary materials in other things. Its history is the evidence of the wisdom and perseverance of chemists, and it is also one of the ways of chemical research.
    Product Overview
    3-Chloro-4-fluorobromobenzene is also an organic compound. Its shape and color are either colorless liquid or white crystal under normal conditions, with a special smell. This substance is widely used in the field of organic synthesis.
    can be used as a key intermediary to prepare a variety of medicines, pesticides and materials. Its chemical properties are active, and the introduction of chlorine, fluorine and bromine atoms makes the molecule unique in its reactivity and selectivity.
    The preparation method often starts with a specific benzene derivative and is obtained by a series of reactions such as halogenation. The conditions of the reaction, such as temperature, the type and amount of catalyst, all have a significant impact on the purity and yield of the product.
    When using this substance, it is also necessary to pay attention to its safety. Because it contains halogen atoms, or has certain toxicity and corrosiveness, when operating, strict procedures should be followed to ensure the safety of the experimenter and the harmlessness of the environment.
    Physical & Chemical Properties
    The physical properties of 3-chloro-4-fluorobromobenzene are important for chemical research. This compound, depending on its physical properties, is either at room temperature or in a solid state, with a certain crystal shape. Its melting point and boiling point are crucial for the separation, purification and application of substances.
    In terms of its chemical properties, the existence of halogen atoms makes it active. The electronegativity of chlorine and fluorine makes the electron cloud density of the benzene ring change, which affects the electrophilic substitution reaction. Bromine atoms can also participate in many reactions, such as substitution with nucleophiles, or elimination under specific conditions.
    In chemical synthesis, this compound is often a key intermediate. With its physical and chemical properties, complex organic molecules can be constructed. Studying its physical properties lays the foundation for the creation of new substances and the development of materials. In the field of organic chemistry, exploring its properties has far-reaching significance and is an important path for scientific research.
    Technical Specifications & Labeling
    Nowadays, in the manufacture of 3-chloro-4-fluorobromobenzene, the process specification and identification (product parameters) are the key. The process specification is the method of synthesis, from the ratio of raw materials, such as the amount of each reactant, accurate to the millimeter, without a slight difference; to the reaction conditions, temperature and pressure control, also need to be just right. The reaction temperature or the reaction rate and product purity, the pressure affects the reaction equilibrium.
    In terms of identification (product parameters), when it is clear that its purity is related to the quality of the product, it must be accurately measured to achieve a very high purity. And its physical properties, such as color and morphology, should also be detailed. The manufacture of 3-chloro-4-fluorobromobenzene, strict adherence to process specifications, clear identification (product parameters), in order to obtain excellent products, in the chemical industry can play its role.
    Preparation Method
    The preparation of 3-chloro-4-fluorobromobenzene involves raw materials and production processes, reaction steps and catalytic mechanisms.
    To prepare this product, first take an appropriate amount of 3-chloro-4-fluorobenzene as the starting material, supplemented by specific brominating reagents, such as liquid bromine or N-bromosuccinimide (NBS). In a suitable reaction vessel, protect with an inert gas such as nitrogen to ensure a stable reaction environment.
    Heat the reaction system to a certain temperature, which depends on the selected reagents and reaction conditions, usually between tens of degrees Celsius. Add a catalyst, such as iron powder or iron tribromide, to accelerate the reaction process. The catalyst can activate the brominating reagent and enhance its reactivity. At the beginning of the
    reaction, the brominating reagent is acted by the catalyst to generate an active bromine radical. This radical reacts with 3-chloro-4-fluorobenzene, and the bromine atom replaces the hydrogen atom on the benzene ring to form the target product 3-chloro-4-fluorobenzene. During the
    reaction, the reaction process needs to be closely monitored, and the degree of reaction needs to be controlled by means of thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction is completed, the pure 3-chloro-4-fluorobromobenzene product can be obtained through separation and purification steps, such as distillation, extraction, column chromatography, etc.
    Chemical Reactions & Modifications
    The industry of chemical industry is related to the change of all things. In the preparation of 3-chloro-4-fluorobromobenzene, its chemical reaction and modification are crucial.
    In the past, the reaction path of this compound was often complicated. The method used, or the reaction conditions are harsh, requiring high temperature and high pressure, and the energy consumption is quite huge; or the raw materials are rare and expensive. And side reactions are frequent, and the purity of the product is poor.
    Today's people want change. After repeated research, the reaction conditions are improved, and the temperature and pressure are mild to reduce energy consumption. The common raw materials are replaced by rare and expensive materials, reducing the burden of cost. Optimize the reaction process, control the occurrence of side reactions, and the purity of the product is increased.
    Such changes, in the preparation of 3-chloro-4-fluorobromobenzene, the efficiency and quality are advanced, which is a new way of chemical preparation. It is hoped that in the field of chemical industry, it can be widely used to promote the prosperity of the industry.
    Synonyms & Product Names
    I have heard that there is a product name 3 - Chloro - 4 - Fluorobenzene Bromide, which is a chemical product. Its synonymous name and the name of the commodity are also investigated by our generation. The name of the husband is synonymous, so it is widely called, and the name of the commodity is involved in the circulation of the market.
    Guanfu 3 - Chloro - 4 - Fluorobenzene Bromide, or another name, such as the different name of its chemical structure, in order to meet the needs of all kinds of research. And the name of the commodity, the merchant is to facilitate its sale, or to take the name of easy to recognize and remember, to attract the attention of everyone.
    As researchers of chemistry, we must scrutinize their synonymous names and commodity names to clarify their similarities and differences, so that we can explore their academic and industrial applications without misuse, and enjoy the journey of chemistry.
    Safety & Operational Standards
    3-Chloro-4-fluorobromobenzene
    3-chloro-4-fluorobromobenzene is a common chemical in chemical research. In order to ensure the safety of the experiment, the operation is standardized and orderly, and this safe production and operation code is hereby established.
    Be careful when storing. 3-chloro-4-fluorobromobenzene should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, it is easy to produce danger when mixed with other chemicals, so it needs to be stored separately, and clearly labeled, indicating the name, nature and precautions.
    When taking it, it is necessary to strictly follow the standard process. Experimenters must wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to prevent chemicals from coming into contact with the skin and eyes. The taking tools must be clean and dry to avoid impurities from mixing. The dosage should be accurately weighed and used accurately according to the needs of the experiment to prevent waste and prevent subsequent treatment difficulties due to excessive use.
    During the experimental operation, pay more attention. The reaction device must be stable and well sealed to prevent chemical leakage. The reaction conditions such as temperature, pressure, time, etc. must be strictly controlled. When heating the reaction, it is advisable to use a suitable heating method, slowly heat up, closely monitor the temperature change, and beware of the reaction being out of control due to excessive temperature.
    After the experiment is completed, the remaining 3-chloro-4-fluorobromobenzene and reaction products should be properly disposed of. It should not be dumped at will, and appropriate methods should be used for harmless treatment or recycling according to the nature of the chemical.
    Anyone who participates in 3-chloro-4-fluorobromobenzene-related experiments should be familiar with this safety production and operation specification, and always be vigilant to ensure the safety and order of the experimental process, protect the safety of themselves and others, and maintain the stability of the experimental environment.
    Application Area
    3 - Chloro - 4 - Fluorobenzene Bromide (3 - Chloro - 4 - Fluorobenzene Bromide) is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. Due to the properties of halogen atoms, it can participate in many chemical reactions, helping to construct complex drug molecular structures to achieve specific pharmacological effects.
    In the field of materials science, it also has potential. With its unique chemical structure, it may be used to create new functional materials. For example, in the field of electronic materials, it may be reacted appropriately to make it an integral part of optimizing the electrical properties of materials.
    Furthermore, in the field of fine chemicals, this compound can be used as a starting material to derive various high-value-added fine chemicals through multi-step reactions to meet the needs of different industries and scientific research. In fact, it is a compound with important application value in many fields.
    Research & Development
    Yu Yanhua has been in the chemical industry for many years, and recently he has been focusing on the analysis of 3-chloro-4-fluorobromobenzene. This compound has great potential in the field of organic synthesis.
    At the beginning, study its structure in detail, explore the wonder of atomic arrangement, think about its chemical bonds, and understand its physicochemical properties. Then study the preparation method, or the technique of halogenation, or follow other paths, examine the advantages and disadvantages of each method in detail, and seek the way of high efficiency and purity.
    During the experiment, strictly control the conditions, temperature and humidity, and the proportion of reactants. Observe the reaction process, the purity of the precipitated product, and try it repeatedly to get the best result.
    Looking forward to the future, we hope to improve the preparation process, reduce costs and increase efficiency. And we expect this product to be widely used in the fields of medicine and materials to promote the progress of the chemical industry and the development of the industry.
    Toxicity Research
    Today there is a product named 3-chloro-4-fluorobromobenzene, and we focus on toxicity research. The chemical quality of this product is related to everyone's health and environmental safety, and cannot be ignored.
    Detailed investigation of this 3-chloro-4-fluorobromobenzene, its unique structure and atomic phase make it special. At the toxic end, we observe that it interacts with various molecules in the body. Or enter the cell and disturb its normal functions, such as enzyme activity and gene expression.
    After various experiments, we observe its impact on the physiology of small animals. Looking at its abnormal behavior and organ damage, we can see that its toxicity is not light. However, we also think about whether the degradation and transformation in the environment will generate new toxins. Therefore, we should continue to study, explore the root cause of its toxicity, and seek protection and resolution strategies to ensure the safety of all things. This is the important task of our chemical researchers.
    Future Prospects
    I have dedicated myself to the research of 3 - Chloro - 4 - Fluorobenzene Bromide. Looking at it, it has unique characteristics, and in various fields of chemical industry, it must have a bright future.
    Today's technology is new, and the research method is refined. With time, we will be able to learn more about its characteristics, explore its optimal system, improve its yield, and improve its quality. At that time, this product may be widely used in medicine to add strength to the elimination of diseases; or apply it to materials to add new energy.
    Although there may be thorns in the road ahead, we scientific researchers must move forward with determination and courage. We hope to make unremitting efforts to expand the untapped grand path of this product, make it shine in the future, and contribute to the progress of the world.
    Where to Buy 3-Chloro-4-Fluorobenzene Bromide in China?
    As a trusted 3-Chloro-4-Fluorobenzene Bromide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Chloro-4-Fluorobenzene Bromide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3-Chloro-4-Fluorobenzene Bromide?
    The main uses of 3-chloro-4-fluorobenzene and bromide are related to many fields. Let me tell you in detail.
    In the field of organic synthesis, its role is quite crucial. It can be used as an important intermediate in organic synthesis to help build complex organic compounds. Chemists can use clever chemical reactions to interact 3-chloro-4-fluorobenzene with bromide to introduce specific functional groups, laying the foundation for the synthesis of organic molecules with unique structures and properties. For example, in the field of drug development, the construction of many drug molecules requires such compounds as starting materials, and through multi-step reactions, the structure of drug molecules can be precisely shaped to achieve specific pharmacological activities.
    Furthermore, in the field of materials science, it also has important functions. The organic materials involved in the synthesis may have special optical and electrical properties. Such materials can be applied to optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), solar cells, etc. The materials synthesized from 3-chloro-4-fluorobenzene and bromide can optimize the performance of devices, improve the photoelectric conversion efficiency, enhance the luminous effect, and contribute to the progress of materials science.
    In the field of pesticides, it also plays an important role. After rational design and reaction, pesticide ingredients with high insecticidal, bactericidal or herbicidal activities can be synthesized. With its unique chemical structure, it can precisely act on specific targets of pests, inhibit their growth and reproduction, and provide a powerful tool for pest control in agricultural production to ensure crop harvest.
    In addition, in the field of fine chemicals, 3-chloro-4-fluorobenzene and bromide can be used to prepare various fine chemicals, such as fragrances and dyes. In the synthesis of fragrances, it can endow fragrances with unique aroma and stability; in the preparation of dyes, it can optimize the color and fastness of dyes to meet the diverse needs of different industries for fine chemicals.
    3-Chloro-4-Fluorobenzene the physical properties of Bromide
    3-Chloro-4-fluorobromobenzene is an organic compound with unique physical and chemical properties. Its appearance is often colorless to light yellow liquid, and it is relatively stable at room temperature and pressure.
    Looking at its physical properties, this compound has a density greater than that of water, and it will sink to the bottom when placed in water. Its boiling point is closely related to the intermolecular force. Due to the presence of halogen atoms such as chlorine, fluorine, and bromine, the intermolecular force is large, resulting in a relatively high boiling point, about 170-190 ° C. The specific value varies depending on the experimental conditions. The melting point depends on the regularity of the molecular arrangement. The melting point of this compound is relatively low, about -10-10 ° C. This characteristic makes it exist in liquid form at room temperature.
    3-chloro-4-fluorobromobenzene is insoluble in water because it is a non-polar or weakly polar molecule, while water is a polar molecule. According to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in many organic solvents, such as ether, dichloromethane, toluene, etc. These organic solvents are often used as reaction media in organic synthesis reactions, so that 3-chloro-4-fluorobromobenzene can be uniformly dispersed, which is conducive to the reaction.
    In addition, 3-chloro-4-fluorobromobenzene is volatile, and in poorly ventilated environments, its volatile vapor may diffuse in the air. Due to its halogen-containing atoms, steam has a certain pungent odor, which requires operation in a well-ventilated environment to ensure the safety and health of personnel.
    3-Chloro-4-Fluorobenzene Bromide's chemical stability?
    3-Chloro-4-fluorobromobenzene is chemically stable to a certain extent. Looking at its structure, chlorine and fluorine atoms are attached to the benzene ring, both of which have electron-withdrawing effects. However, the benzene ring structure has a certain conjugate stability, and the three interact. In the conventional environment, it is difficult to change significantly without strong interaction.
    If placed in a mild environment, such as room temperature and pressure, and there is no active reagent interference, this compound can persist for a long time and change little. However, if it encounters strong oxidants, such as permanganic acid, although the benzene ring is stable, the side chain may react. And if it encounters nucleophilic reagents, due to halogen atoms, or nucleophilic substitution reactions. Among them, the bromine atom is relatively active and is easier to be replaced by nucleophiles.
    Under light or heating conditions, it may initiate free radical reactions, and the halogen atom can dissociate into free radicals under specific conditions, thereby triggering a chain reaction. But in general, without such special conditions, the chemical properties of 3-chloro-4-fluorobromobenzene are still stable and do not easily react violently with common substances.
    3-Chloro-4-Fluorobenzene is the production process of Bromide
    3-Chloro-4-fluorobromobenzene is prepared by the following process:
    The starting material is 3-chloro-4-fluorobenzene. To obtain the target product, bromine atoms must be introduced at specific positions on the benzene ring.
    This preparation often involves electrophilic substitution reactions. Due to the characteristics of electron cloud density distribution in the benzene ring, the specific position substitution needs to be guided by a suitable locator. In 3-chloro-4-fluorobenzene, chlorine atoms and fluorine atoms are ortho-para-site locators.
    The reaction often takes liquid bromine as the bromine source and is carried out under the action of a suitable catalyst. Iron or its halide (such as iron tribromide) is often used as a catalyst for this reaction. Its principle of action is: the reaction of iron and bromine to form iron tribromide, and the interaction of iron tribromide and bromine polarizes the bromine to form a highly active electrophilic reagent, which is conducive to the occurrence of the electrophilic substitution reaction of the benzene ring.
    For specific operation, in the reaction vessel, add 3-chloro-4-fluorobenzene and an appropriate amount of catalyst, and slowly add liquid bromine dropwise under low temperature and stirring conditions. Due to the exothermic reaction, the temperature needs to be strictly controlled to prevent side reactions from occurring. If the temperature is too high, bromination may occur at other positions of the benzene ring to form poly
    After the reaction is completed, the product needs to be separated and purified. First, it is washed with water to remove impurities dissolved in water, such as hydrobromic acid generated by the reaction and catalyst decomposition products. Then it is extracted with an organic solvent to enrich the product in the organic phase. Then by distillation or distillation, high-purity 3-chloro-4-fluorobromobenzene is separated according to the difference between the boiling points of the product and the impurities.
    The whole preparation process, the selection of raw materials, the control of reaction conditions, and the separation and purification of the product are all key to ensure high yield and high-purity product formation.
    What are the precautions in storage and transportation of 3-Chloro-4-Fluorobenzene Bromide?
    When storing and transporting 3-chloro-4-fluorobenzene and bromide, many matters need to be paid attention to.
    Safety is the first priority. These two may be toxic, corrosive, or flammable and explosive. When storing, choose a dry, cool and well-ventilated place, away from fire and heat sources. The temperature of the warehouse should be stable and the humidity should also be controlled to prevent sudden changes in temperature and humidity from changing the properties of substances and causing danger. And the two should be stored separately from oxidizing agents, reducing agents, acids, alkalis, etc., and must not be mixed in storage, because they react with each other or cause fire, explosion and other disasters.
    When transporting, the packaging must be solid. Use appropriate packaging materials to ensure that there is no leakage during transportation bumps. Transportation vehicles need to be equipped with corresponding fire equipment and emergency treatment equipment to prevent accidents. Transportation personnel should also be professionally trained to be familiar with the characteristics of the transported substances and emergency response methods.
    Furthermore, it is essential to mark clearly. Storage containers and transportation packages should be marked with material names, characteristics, hazard warnings and other prominent labels so that relevant personnel can identify, operate and protect correctly.
    At the same time, strictly follow relevant regulations. Storage and transportation operations should comply with national and local safety, environmental protection and other regulations, complete various procedures, and keep detailed records for inspection.
    Only by following these steps with care can the safety of 3-chloro-4-fluorobenzene and bromide be ensured during storage and transportation.