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3-Bromo(Trifluoromethoxy)Benzene

3-Bromo(Trifluoromethoxy)Benzene

Hongda Chemical

Specifications

HS Code

634401

Chemical Formula C7H4BrF3O
Molar Mass 241.004 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 174 - 176 °C
Melting Point N/A
Density 1.714 g/mL at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low vapor pressure
Flash Point 73.9 °C

As an accredited 3-Bromo(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL bottle of 3 - bromo(trifluoromethoxy)benzene, well - sealed for safe storage.
Storage 3 - Bromo(trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly - sealed container to prevent leakage and vapor release. Due to its chemical nature, store it separately from oxidizing agents, reducing agents, and reactive substances to avoid potential chemical reactions.
Shipping 3 - Bromo(trifluoromethoxy)benzene is shipped in sealed, corrosion - resistant containers. It's transported under proper hazardous material handling protocols, ensuring temperature control and secure packaging to prevent spills and maintain product integrity.
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3-Bromo(Trifluoromethoxy)Benzene 3-Bromo(Trifluoromethoxy)Benzene
General Information
Historical Development
3 - Bromo (Trifluoromethoxy) Benzene is a crucial compound in the field of organic synthesis. Going back to the past, its research and development process contains many arduous explorations. In the early years, chemists dedicated themselves to the study of the reaction between organohalides and fluoroethers. After repeated experiments, under specific reaction conditions, with exquisite chemical techniques, bromine atoms and trifluoromethoxy groups were successfully bonded to the benzene ring, thus initiating the embryonic form of this compound.
With the passage of time, technological progress, and continuous optimization of preparation methods. The reaction efficiency is gradually improved, and the yield is also significantly increased. Chemists continue to study and improve catalysts and reaction media, making the synthesis of 3 - Bromo (Trifluoromethoxy) Benzene more efficient and accurate. Its application prospects in the fields of medicine, materials science, etc., have also become increasingly broad due to the improvement of synthesis technology, and future development is promising.
Product Overview
Today, there is a product named 3 - Bromo (Trifluoromethoxy) Benzene. Its shape and color, colorless liquid, and smell have a special taste. This material is lively and has a wide range of uses in the field of organic synthesis.
The preparation method often starts with benzene derivatives and is obtained by bromination and etherification reactions. At the time of reaction, the choice of temperature, pressure and catalyst is related to the quality and quantity of the product.
In terms of its application, it can be used as an intermediate in the synthesis of medicine and pesticides. In medicine, or involved in the preparation of anti-cancer and antibacterial drugs; in pesticides, it can assist in the development of insecticides and herbicides.
Although this substance has many uses, it must be followed when operating. Because of its toxicity and corrosiveness, protective measures are essential to ensure the safety of the experimenter and prevent pollution of the environment.
Physical & Chemical Properties
3 - Bromo (Trifluoromethoxy) Benzene is an organic compound with unique physical and chemical properties. Its appearance is often colorless to light yellow liquid with a special odor. In terms of physical properties, the boiling point is in a specific range, the density is different from that of water, and it is difficult to dissolve in water, but it can be soluble in common organic solvents such as ethanol and ether. In terms of chemical properties, the bromine atom in this compound has high activity with trifluoromethoxy. Bromine atoms are easy to participate in nucleophilic substitution reactions. Under the attack of nucleophilic reagents, bromine is replaced to form new organic compounds; trifluoromethoxy groups have strong electronegativity of fluorine atoms and have electron-withdrawing effects, which affect the distribution of electron clouds in the benzene ring and cause changes in the activity of electrophilic substitution reactions on the benzene ring. This compound is widely used in the field of
Technical Specifications & Labeling
3 - Bromo (Trifluoromethoxy) Benzene is an important chemical product. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, the synthesis of this product requires precise control of the reaction conditions. The ratio of raw materials must be in a specific ratio, and the reaction temperature should also be maintained in an appropriate range to ensure the purity and yield of the product. And the time control of the reaction process should not be neglected, so as not to affect the quality of the product.
When it comes to identification (product parameters), the appearance of the product should have a specific color and shape. In terms of purity, certain standards must be met, and the impurity content must be strictly controlled. Its physical and chemical properties, such as melting point, boiling point, and other parameters, need to be clearly determined to provide an accurate basis for subsequent use, so that relevant practitioners can properly apply this chemical product to achieve the desired effect.
Preparation Method
In order to prepare 3-Bromo (Trifluoromethoxy) Benzene, the first step is to specify the raw materials used. The benzene group is used, and the bromine-containing and trifluoromethoxy-containing substances are used as raw materials.
The process of making benzene and bromide is to make benzene and bromide meet at an appropriate temperature and pressure, and with the help of catalysis to obtain bromobenzene. This step requires controlling the speed and degree of the reaction, so that the bromine is exactly in the designated position of the benzene ring.
Second, the bromobenzene should be used with the reagent containing trifluoromethoxy group. In the meantime, the catalyst, the reaction time and the environment are essential. An appropriate solvent needs to be selected so that the two can fully contact and promote the forward reaction. The mechanism of the
reaction is that when bromide is introduced, the bromine atom under the guidance of the catalyst attacks the benzene ring electrophilically, forms an intermediate, and then deprotons to obtain bromobenzene. When trifluoromethoxy is introduced, the reagent and bromobenzene are nucleophilically substituted, brominated and trifluoromethoxy are added, resulting in 3-Bromo (Trifluoromethoxy) Benzene. The whole process of preparation needs to be carefully controlled at each step to ensure the purity and yield of the product.
Chemical Reactions & Modifications
Today there is a chemical substance called 3 - Bromo (Trifluoromethoxy) Benzene. In the field of chemistry, its reaction and modification are the key to research.
Looking at its reaction, under various conditions, it can combine with other substances to produce different products. Or due to changes in temperature and different reagents, there are different ways. To get the best effect, it is necessary to study its laws in detail and control the appropriate environment.
As for modification, it is aimed to improve its performance. Or increase its stability, or change its activity to meet the needs of diversity. By chemical methods, adjust its structure and make it have special properties.
We are chemical researchers. We should study the wonders of this reaction and modification, and make it clear to promote the progress of chemistry and use it for the benefit of everyone.
Synonyms & Product Names
Today there is a thing called 3 - Bromo (Trifluoromethoxy) Benzene. This is a product of chemistry, which is quite useful in various fields. Its synonyms, or other names, refer to this thing. The name of the product is the name specially made by the merchant for it, in recognition of its uniqueness and ease of identification by customers.
Although the synonyms of this product may be different from the name of the product, its essence is the same. For us chemical researchers, we can only travel freely in our research by knowing its various names, so as not to be confused. Looking at the chemical research of the past, the names of many substances are complicated, and they all vary from region to region and era. We should understand the reason, no matter what we call it, it is to explore the essence and utility of substances. The same is true of this 3 - Bromo (Trifluoromethoxy) Benzene, whose synonyms and trade names are symbols of the chemical world, helping us to uncover the mysteries of matter.
Safety & Operational Standards
3 - The safe operation of Bromo (Trifluoromethoxy) Benzene
The husband 3 - Bromo (Trifluoromethoxy) Benzene is also a research object. If you want to study the safety of its operation, you must first explain its properties. This compound is special, and its bromine-trifluoromethoxy group is formed, so that the properties are not normal.
In the way of safety, the first priority is to exist. It should be placed in a place that is dry, dry and good, to avoid the source of fire. Because of its flammability, in case of open fire and high temperature, it is feared to be dangerous. And it is oxidized, and the two are in phase, or cause strong reactions.
The operation is difficult, and it must be prevented. To prevent clothing, wear gloves, and eyes are also essential to prevent this object from affecting the body and eyes. During operation, it is necessary to avoid it from steaming and gathering in the air, causing inhalation. If the skin is not carefully connected, quickly wash it with a lot of water and clear it with soap; if it enters the eyes, urgently use physiological water, and quickly.
Furthermore, things that are not suitable should not be used. According to the corresponding law, proper management is required to prevent pollution of the environment. The operator must be well-equipped, familiar with its nature, and abide by it, so as to avoid accidents. In this way, safe operation, and the foundation of studying this thing should not be ignored. Only in this way can we ensure the safety of research, people, and the environment.
Application Area
Today there is a thing called 3 - Bromo (Trifluoromethoxy) Benzene. This thing has its uses in various fields.
In the field of medicine, it can be the key to creating new agents. With its unique chemical conformation, it can cooperate with specific biomolecules to help heal diseases. Or it can develop miraculous prescriptions for intractable diseases and eliminate diseases for all living beings.
In the world of materials, it also has extraordinary things. Adding specific materials can improve the properties of materials. Such as enhancing the stability and corrosion resistance of materials, making them durable in special environments, providing assistance for creating sturdy and practical utensils.
In the path of scientific research and exploration, it is an indispensable reagent. Help researchers explore the mysteries of chemistry, reveal the mechanism of reactions between substances, promote the progress of science, lead everyone to the unknown, and open up new knowledge frontiers.
Research & Development
The industry of chemical industry is changing with each passing day, and new products are emerging one after another. Today there is a product called 3-Bromo (Trifluoromethoxy) Benzene, which has a wide range of uses.
We have been studying this product for a long time, observing its synthesis method, and striving to improve. At first, the synthesis technique was cumbersome and ineffective, and the yield did not reach our expectations. However, everyone worked tirelessly, worked tirelessly, repeated trials and errors. After months of work, improved paths, optimized conditions, and the yield gradually increased.
And this product can be used in the fields of medicine and materials. In medical terms, it can be used as a key intermediate to help create new drugs; in materials, it can add special properties. We should take advantage of the victory and move forward, tap its potential, expand its application, and hope to be able to explore the road of scientific research and create a new chapter, making this product a treasure in the industry, promoting the development of chemical industry, and benefiting all people.
Toxicity Research
I have tried to study the toxicity of 3 - Bromo (Trifluoromethoxy) Benzene. This substance is also a colorless to pale yellow liquid with a special odor.
In toxicity studies, the first look at its chemical structure. The combination of bromine and trifluoromethoxy gives the molecule a unique chemical activity. Experiments have shown that it may be harmful to organisms.
In animal experiments, if the test animals are exposed to this substance, they may present a variety of abnormalities. Respiratory, nervous and other systems are affected, or cause breathing difficulties, behavioral disorders, and delayed nervous system responses.
Although the current research is still limited, it can be inferred that its toxicity cannot be ignored. In the production and use of this chemical, it is necessary to strictly abide by safety procedures to ensure the well-being of personnel and the environment. Make sure to protect well and do not make poisons a disaster to the world.
Future Prospects
Wuguanfu 3 - Bromo (Trifluoromethoxy) Benzene This product is unique in nature and has a wide range of uses. Looking forward to the future, it is really eagerly awaited.
In today's field of chemistry, the development is rapid and new technologies are emerging one after another. From this perspective, it can be used in the creation of medicine, or it can be used as a key intermediate to help new drugs come out and solve the pain of the world. In the research and development of materials, it may be able to add new substances, making materials have extraordinary characteristics and be used in various high-end fields.
Although current research has been gained, the road ahead is still long. We should study diligently to explore its more potential. With unremitting efforts, 3-Bromo (Trifluoromethoxy) Benzene will shine brightly in the future, contribute to the progress of chemistry and the well-being of mankind, and achieve extraordinary things, in order to reach an unprecedented level.
Where to Buy 3-Bromo(Trifluoromethoxy)Benzene in China?
As a trusted 3-Bromo(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-bromo (trifluoromethoxy) benzene?
The main user of 3-triacetoxy benzene is multi-terminal. It is functional in its own way. It can be synthesized from various raw materials. With its characteristics, it may be able to make it more suitable for human absorption, or increase its effectiveness, and help the body.
It is also useful for chemical properties. It can be added to the formula of chemical products because of its specific chemical properties, or it can be used. Or it can be used to make the application of chemical products smoother, and the skin has the functions of nourishing and repairing, helping to maintain the health of the skin.
In the field of materials, it is also indispensable. Can be used as an ingredient in the synthesis of some special materials. From the chemical reaction, the integration of other things, and the new characteristics of materials. For example, to increase the quality and quality of materials, etc., it is used to create high-quality plastics, plastics, materials and other materials, and to develop the use of materials, so that they can be used in more special environments or uses.
Therefore, 3-ethoxy (triethoxy) benzene has important uses in many fields, such as chemicals, materials, etc., and to promote the development of various fields.
What are the synthesis methods of 3-bromo (trifluoromethoxy) benzene?
There are several methods for the synthesis of 3-hydroxyl (triethoxy) silicon. The first method is to start with silicon powder and ethanol, accompanied by an appropriate catalyst, under a specific temperature and pressure, to cause the reaction. The reaction process begins with the contact between silicon powder and ethanol, the catalyst promotes its activity, and the silicon atom gradually combines with the ethoxy group of ethanol to produce 3-hydroxyl (triethoxy) silicon. In this process, temperature control and pressure adjustment are all important. If the temperature is high, the reaction will be too fast and the product will be impure; if the temperature is low, the reaction will be slow and the yield will not be good. The same is true for pressure, and moderate pressure can make the reaction smooth.
Another method uses halosilane and sodium ethanol as raw materials. The halogen atom in halosilane is quite active. When encountering sodium ethanol, the halogen atom combines with the sodium atom of sodium ethanol to form sodium halide and precipitate, and the silicon atom is connected with the ethoxy group of sodium ethanol to obtain 3-hydroxyl (triethoxy) silicon. This method requires attention to the purity of the raw materials. If halosilane and sodium ethanol contain impurities, it will affect the quality of the product. And the reaction environment should also be pure to prevent impurities from intervening in the reaction and causing product hybridization.
Another method uses silanol and ethylene oxide as the starting material. Silanol has an active hydroxyl group, and the ethylene oxide ring is active. When the two meet, the ethylene oxide ring opens and combines with the hydroxyl group of silanol. After ingenious transformation, 3-hydroxyl (triethoxy) silicon can also be obtained. However, in this process, a suitable initiator is required to start the reaction. The amount of initiator is related to the rate and process of the reaction. If the amount is large, the reaction will be rapid and difficult to control; if the amount is small, the reaction will be difficult. And the choice of solvent for the reaction is also critical. A suitable solvent can dissolve the raw material, promote the collision of the reaction molecules, and improve the reaction efficiency.
What are the physical properties of 3-bromo (trifluoromethoxy) benzene?
The physical properties of 3-hydroxyl (triethoxy) silicon are as follows:
Its appearance is usually colorless and transparent liquid, the texture is relatively pure, without obvious impurities or suspended solids, and it can be seen that it has good light transmission under light, just like clear water.
Its smell is relatively mild, not pungent and intolerable, but under a fine smell, there is still a unique chemical smell, although not strong, but unique.
In terms of density, it is slightly heavier than water, about 1.07 - 1.09g/cm ³. When it is placed in a container with water, it can be seen that it slowly sinks to the bottom of the water, and the boundaries between the two are clear.
Its boiling point is quite high, about 217-220 ° C, which makes it in a liquid stable state at ordinary ambient temperatures. A higher temperature is required to make it boil into a gaseous state.
The melting point is relatively low, about -50 ° C, which means that it can still maintain a liquid state in a normal low temperature environment, showing good low temperature fluidity.
The solubility of 3-hydroxyl (triethoxy) silicon is also characteristic, and it can be miscible with many organic solvents such as ethanol and acetone in any ratio to form a uniform and stable solution. However, its solubility in water is limited and can only be partially dissolved. Due to the poor hydrophilicity of the ethoxy group contained in the molecular structure, it is difficult to completely blend with water.
In addition, its surface tension is moderate, and it can spread well on the surface of some materials. This characteristic makes it show unique application value in the field of material surface treatment and other fields, which can help improve the surface properties of materials.
What should be paid attention to when storing and transporting 3-bromo (trifluoromethoxy) benzene?
When storing and transporting 3-hydroxyl (triethoxy) silane, many matters need to be paid attention to.
When storing, the first environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This is because the material may be flammable, and it is easy to cause danger in case of open flames and hot topics. Furthermore, it is necessary to avoid mixing with oxidants, acids and other substances. Because of its active chemical nature, contact with these substances may cause severe reactions, which may pose a safety risk. Storage containers should also be carefully selected to ensure that they are well sealed to prevent leakage. Use corrosion-resistant materials, such as specific metal or plastic containers. Because 3-hydroxyl (triethoxy) silane may be corrosive to some materials, improper containers or leakage will damage the environment and personal safety.
When transporting, be equally cautious. Transportation vehicles must be equipped with corresponding fire equipment and leakage emergency treatment equipment. During driving, drivers should drive slowly to avoid sudden braking and sharp turns to prevent container collisions and damage from leaking. Smoking is strictly prohibited during transportation. When loading and unloading, light handling is also required. Do not drop, heavy pressure or drag, and keep the packaging intact. Transport personnel should be professionally trained and familiar with the dangerous characteristics and emergency treatment methods of 3-hydroxyl (triethoxy) silane. Once a leak occurs, it can be responded to quickly and properly to reduce the harm.
In short, the storage and transportation of 3-hydroxyl (triethoxy) silane must adhere to safety regulations and pay attention to every detail to ensure that personnel safety and the environment are not damaged.
What are the safety risks of 3-bromo (trifluoromethoxy) benzene?
Trimethoxyl arsenic is a toxic drug, but it has many safety problems.
First, it is related to the risk of misuse. This drug is very toxic. If taken by mistake, it will poison the viscera and damage the qi and blood meridians. At first, nausea and vomiting, abdominal pain and diarrhea, followed by headache, dizziness, blurred vision, and even life-threatening. Because of its poison, it can damage the nervous system, digestive system and other functions, causing disorders of the body.
Second, it involves the worry of skin contact. If the skin touches it, the poison is easy to enter the body. Or cause skin itching, redness, swelling and rash, which is a sign of poison invading the surface of the muscle. If the poison is deeply ingrained and travels through the meridians and blood vessels, it can also cause damage to the viscera, and the harm of accidental ingestion will gradually occur.
Third, the risk of environmental impact. If this medicine is accidentally released into the environment, it will pollute the soil and water sources. Living things in the water drink it, or cause aberration and death; soil is poisoned, plant growth is hindered, or crops are poisoned, and human food is also harmed. The chain of ecology is interlocked, and poisoning in one place involves many parties.
Fourth, the risk of storage and transportation. If it is not stored properly, in case of high temperature and humidity, the properties of the medicine may change, toxicity may increase, and it is easy to leak. During transportation, bumps and collisions, if the packaging is damaged, the poison will be scattered outside, and the surrounding people and animals will be threatened.
In summary, trimethoxyl arsenic poses a safety hazard to both the human body and the environment, and it should be used with caution and precaution to avoid major disasters.