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3-Bromo-5-(Trifluoromethyl)Nitrobenzene

3-Bromo-5-(Trifluoromethyl)Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    195773

    Chemical Formula C7H3BrF3NO2
    Molar Mass 286.003 g/mol
    Appearance Solid (Typical)
    Solubility In Water Insoluble (Expected, due to non - polar nature of the aromatic ring and hydrophobic groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (Expected for aromatic nitro - halide compounds)
    Stability Stable under normal conditions, but may react with strong reducing agents, strong bases

    As an accredited 3-Bromo-5-(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3 - bromo - 5 - (trifluoromethyl)nitrobenzene packaged in a sealed glass bottle.
    Storage 3 - bromo - 5 - (trifluoromethyl)nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and reducing agents due to potential reactivity. Label the storage clearly for easy identification and safety.
    Shipping 3 - bromo - 5 - (trifluoromethyl)nitrobenzene is shipped in well - sealed, corrosion - resistant containers. Special handling precautions are taken due to its chemical nature, ensuring compliance with hazardous material shipping regulations.
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    3-Bromo-5-(Trifluoromethyl)Nitrobenzene 3-Bromo-5-(Trifluoromethyl)Nitrobenzene
    General Information
    Historical Development
    3-Bromo-5- (trifluoromethyl) nitrobenzene is also an organic chemical. The beginning of its traceability is that chemists explore in the microscopic end, analyze the secrets of molecules, and investigate the wonders of structures. In the past, all sages used simple tools and tenacious hearts to pursue the truth of chemistry.
    At the beginning, the understanding of this thing was still shallow, and only a few or two characteristics were glimpsed. However, scholars have studied it endlessly, and after repeated trials, they have gradually understood the method of its synthesis with wisdom and sweat. Beginning with simple raw materials and complex reactions, this compound was obtained.
    The years have passed, the technology has improved, and the synthesis methods have become more and more exquisite. From the beginning of the extensive, to today's precision, every step is soaked in the blood of chemists. As a result, 3-bromo-5- (trifluoromethyl) nitrobenzene has emerged in the chemical industry, medicine and other fields, and has a wide range of uses. It is a brilliant pearl in the development of chemistry.
    Product Overview
    Today there is a substance called 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene. The properties of this substance can be particularly investigated. Its shape and color, or a specific appearance, must be obtained by real observation. Its structure is exquisite, bromine atoms, trifluoromethyl groups and nitro groups are combined on the benzene ring to form this unique shape.
    Regarding its preparation, it must go through many wonderful methods. Or derived from the benzene ring, by means of various reagents and delicate reactions, bromine is gradually added, trifluoromethyl groups and nitro groups are added, and the temperature, duration and proportion of reagents need to be carefully controlled in order to obtain this pure substance.
    is also widely used, in the synthesis of medicine, or as a key intermediate, to assist in the creation of new drugs; in the process of material research and development, or to endow materials with specific properties, such as enhancing their stability, changing their electrical properties, etc. The wonders of this substance, we need to use scientific methods to explore in depth, so as to understand more mysteries and use them for the world.
    Physical & Chemical Properties
    3-Bromo-5- (trifluoromethyl) nitrobenzene is an important chemical compound in chemical research. Its physical and chemical properties are worth studying in detail. Looking at its physical properties, at room temperature, or as a solid state, it has a specific color and state. The genera of its melting point and boiling point are also key physical properties, which are related to its existence form under different conditions.
    When it comes to chemical properties, due to the presence of bromine, trifluoromethyl and nitro functional groups, the reactivity is unique. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reactions, but it is easy to cause nucleophilic substitution. Bromine atoms can participate in a variety of substitution reactions and can use specific reagents to achieve the conversion of functional groups. The existence of trifluoromethyl groups endows molecules with unique chemical stability and hydrophobicity. All kinds of properties have important application value in the fields of organic synthesis and materials science, and are indispensable objects in chemical research.
    Technical Specifications & Labeling
    Today there is a product called 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene. The process of its preparation is related to many delicacies. The first thing to do is to choose the right raw materials and match them in precise proportions. When reacting, temperature control and pressure control are the top priorities. If the heat is slightly poor, the product will be impure.
    As for the identification of the product (commodity parameters), its purity needs to be specified, which is the key to quality. The appearance should also be clearly described, and the color and shape cannot be omitted. And its physical and chemical properties, such as melting point, boiling point, etc., need to be accurately determined and marked in detail. In this way, this product can be used in the field of chemical industry, providing a reliable foundation for various applications, and strictly abiding by process regulations and accurate identification to obtain the best products.
    Preparation Method
    To prepare 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene, the method is as follows:
    Raw materials and production process: Select aromatic hydrocarbons containing fluorine and bromine as starting materials. This raw material needs to have a specific electron cloud distribution for subsequent reaction. Appropriate halogenating reagents, such as compounds containing bromine and fluorine, are used under the action of catalysts to introduce bromine and trifluoromethyl into aromatic hydrocarbons.
    Reaction steps: First place the aromatic hydrocarbons in a reactor, control the temperature in a specific range, add an appropriate amount of catalyst, slowly drop the halogenating reagent, and continue to stir during the process to promote a uniform reaction. When the reaction is sufficient, adjust the temperature and reaction time in a timely manner according to the reaction process.
    Catalytic mechanism: The catalyst used can reduce the activation energy of the reaction, so that the bromine and trifluoromethyl are precisely located in the specific position of the aromatic hydrocarbon. The active center interacts with the reactant molecules to change the reaction pathway, accelerate the reaction, and improve the selectivity of the product. Finally, 3-Bromo-5- (Trifluoromethyl) Nitrobenzene is obtained.
    Chemical Reactions & Modifications
    In the chemical reaction and modification of 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene, I have gained a lot.
    Looking at the reaction, the bromine atom of this compound is active and can interact with nucleophiles, and the substitution changes. In case of alcohol nucleophiles, under suitable conditions, bromine can be replaced by alkoxy groups to obtain new derivatives. The rate of reaction depends on the reaction conditions such as temperature and catalyst. Raising the temperature, the reaction rate may increase; an appropriate catalyst can also promote the reaction.
    As for the modification, the electron cloud distribution can be adjusted due to the presence of trifluoromethyl and nitro groups. Trifluoromethyl has strong electron absorption, and so does nitro. The synergy between the two can reduce the electron cloud density of the benzene ring and change the activity of the compound in the electrophilic substitution reaction. Or chemical modification can be used to introduce other functional groups to expand its uses, such as in materials science, drug research and development, etc., which are expected to have new applications.
    The beauty of chemistry is to explore the change law of substances, so that we can modify compounds on demand to suit various uses. The study of 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene is also one way to explore this path.
    Synonyms & Product Names
    Today there is a thing called 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene. This thing is very important in my chemical research. The name of its synonym also needs to be studied in detail.
    The way of Guanfu chemistry, the same substance, is called or different. This 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene, or has another name to express it. The name of the synonym, so help us to understand its nature and understand it. Although it is a thing, the name varies depending on the research angle and application scene.
    As for the name of the product, it is also the key. Different trade names, or give them different names. This trade name is related to the circulation of this thing in the market and is valued by merchants and users. Knowing its synonymous name and trade name is like holding the key to open the door, which can lead to chemical research and practical application. It is indispensable for us chemical researchers.
    Safety & Operational Standards
    3-Bromo-5- (trifluoromethyl) nitrobenzene
    Fu3-bromo-5- (trifluoromethyl) nitrobenzene is a common compound in chemical research. It is reactive and must be strictly observed when using and handling to keep it safe.
    For storage, keep it in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because of its certain chemical activity, if the storage environment is not good, it is easy to cause chemical reactions and cause danger. And should be stored separately from oxidants, reducing agents, alkalis, etc., must not be mixed storage, cover the interaction of different chemical substances, or produce violent reactions, endangering safety.
    When operating, be sure to wear appropriate protective equipment. Operators should wear protective clothing, protective gloves and goggles to guard against its harm to the human body. This compound may be corrosive and irritating, and if it touches the skin or eyes carelessly, it will cause disaster. The operation process should be carried out in a fume hood to ensure air circulation, and timely remove volatile harmful gases to prevent their accumulation in the air and endanger the health of the operator.
    The experimental operation steps must also be accurate. When taking it, use appropriate equipment and use it in accurate doses to avoid waste and excess. During the reaction process, pay close attention to the reaction conditions, such as temperature, pressure, reaction time, etc. The reaction in which this compound participates may be harsh on the conditions, slightly deviated, or cause the reaction to go out of control, resulting in adverse consequences.
    If a leak occurs accidentally, do not panic. Personnel in the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency responders must wear self-contained positive pressure breathing apparatus and anti-toxic clothing to cut off the source of the leak as much as possible. In the case of a small leak, a mixture of sand, dry lime or soda ash can be used and collected in a dry, clean, covered container. A large number of leaks need to be built embankments or excavated to contain, covered with foam to reduce vapor disasters, and then transferred to tanks or special collectors by pumps, recycled or transported to waste treatment sites for disposal.
    In short, in the research and use of 3-bromo-5- (trifluoromethyl) nitrobenzene, safety and operating standards are the top priority. Only by following strictly can the experiment be smooth and personnel safety be ensured.
    Application Area
    3-Bromo-5- (trifluoromethyl) nitrobenzene has a wide range of application fields. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, it contains functional groups such as bromine, trifluoromethyl and nitro, which can participate in a variety of chemical reactions.
    At the end of drug development, it can be used to build a specific molecular skeleton or to derive compounds with unique biological activities, providing an opportunity for the creation of new drugs. In the field of materials science, the introduction of this structure through specific reactions is expected to endow materials with special electrical, optical or chemical stability properties.
    is also indispensable in the preparation of fine chemical products, which can assist in the synthesis of high-end dyes, fragrances and special additives, improve the quality and performance of products, and promote the development of related industries.
    Research & Development
    In recent years, I have been interested in chemical substances, especially 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene. It covers the field of organic synthesis and has great potential for application.
    I began to study this substance, first examining its physicochemical properties. Looking at its structure, bromine, trifluoromethyl and nitro are merged in the benzene ring. This unique structure makes it specific. After experimental tests, its melting point, solubility, etc. are all recorded in the book for subsequent use.
    Then the preparation method was studied. At first, the old method was followed, but the yield was not good. Then think about changes, adjust the conditions of various reactions, and try different reagents and catalysts. After repeated attempts, a better method is finally obtained, the yield is quite high, and the purity of the product is also good.
    At present, although the research of this product is beneficial, it is still necessary to work hard if it is to be widely used. In the future, when it comes to its reaction mechanism, we will further explore it, hoping to expand its application, and make achievements in the fields of medicine and materials, so as to promote the progress of chemistry and be used by the world.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene, and the study of its toxicity is of great importance to our generation.
    This substance contains bromine, fluorine, nitro and other groups, or is toxic. Looking at its structure, bromine atoms are active or lead to chemical reactions, involving biomolecules. Fluorine has strong electronegativity, which makes the molecular stability abnormal. It is difficult to decompose in organisms, and it is feared to accumulate and harm. Nitro is oxidizing, which can cause cell damage and disrupt the balance of the organism.
    Although the exact toxicity to organisms is not detailed, it is inferred according to the structure and chemistry, or damage the liver and kidney, and disturb the nerves. Therefore, those who study this object must abide by strict regulations, protect it well, avoid its escape, avoid harming living beings, and protect nature and the peace of the world.
    Future Prospects
    Wuguanfu 3 - Bromo - 5 - (Trifluoromethyl) Nitrobenzene has its own unique properties, and it has a vast prospect in the field of chemical industry. The future development is expected to emerge in the process of material creation. Its unique structure may become the basis for new functional materials, helping to improve the properties of materials, such as enhancing its stability and optimizing its electrical properties.
    Furthermore, in the path of drug development, there are infinite possibilities. Its unique chemical structure may provide inspiration for the design of new drug molecules, adding a weapon to overcome difficult diseases.
    Although its application may still be in its infancy today, with time, with the advance of science and technology, it will be able to shine brightly, create a new situation in many fields, and become the pillar of future development.
    Where to Buy 3-Bromo-5-(Trifluoromethyl)Nitrobenzene in China?
    As a trusted 3-Bromo-5-(Trifluoromethyl)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Bromo-5-(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Bromo-5- (Trifluoromethyl) Nitrobenzene?
    3-Bromo-5- (trifluoromethyl) nitrobenzene, a crucial compound in the field of organic synthesis, has a wide range of uses and plays a key role in many fields.
    First, in the field of medicinal chemistry, it is often used as a key intermediate. The development of many new drugs requires the construction of specific chemical structures by this compound. Because of its bromine atom, trifluoromethyl and nitro groups, they are all active functional groups, which can participate in various chemical reactions and help generate molecular structures with specific biological activities, laying the foundation for the development of specific drugs for specific diseases.
    Second, in the field of materials science, it also has important uses. Can be used to prepare organic materials with special properties. For example, when introduced into polymer materials through a specific reaction, with the unique properties of trifluoromethyl, such as high electronegativity and strong hydrophobicity, the material can be endowed with excellent chemical corrosion resistance, good thermal stability and unique optical properties, etc., to meet the needs of high-performance materials in the fields of electronics, aerospace and other fields.
    Furthermore, in the field of pesticide synthesis, 3-bromo-5- (trifluoromethyl) nitrobenzene also plays an indispensable role. It can be used as an important starting material for the synthesis of new pesticides. By modifying and transforming its functional groups, pesticides with high insecticidal, bactericidal or herbicidal activities can be synthesized. Due to the introduction of trifluoromethyl, the environmental stability and biological activity of pesticides can be improved, and the dosage of pesticides can be reduced to reduce the impact on the environment. In conclusion, 3-bromo-5- (trifluoromethyl) nitrobenzene, with its unique chemical structure and activity, has shown important application value in many fields such as drugs, materials, and pesticides, and has made great contributions to promoting technological development and innovation in related fields.
    What are the physical properties of 3-Bromo-5- (Trifluoromethyl) Nitrobenzene?
    3-Bromo-5- (trifluoromethyl) nitrobenzene, this is an organic compound with specific physical properties. Its state is solid, stable at room temperature and pressure, but it needs to avoid open flames and hot topics to prevent danger.
    Look at its melting point, about 45-49 degrees Celsius. The melting point is the temperature at which a substance changes from solid to liquid state, which is crucial for identification and purity analysis. The melting point of this compound can be used as one of the identification marks in this range.
    The boiling point is also an important physical property. Its boiling point is about 236-238 degrees Celsius. The boiling point is the temperature at which the saturated vapor pressure of a liquid is equal to the external pressure, reflecting the volatility of the substance. This compound has a higher boiling point and relatively low volatility.
    When it comes to density, it is about 1.829 g/cm ³. The density is the mass of the substance per unit volume, which is helpful for determining the purity of the substance and separating it from other substances. This value indicates that its density is higher than that of common organic solvents.
    In terms of solubility, it is slightly soluble in water. Water is a common solvent, and most organic compounds have poor miscibility with it, and so is this compound. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, etc. This property is commonly used in organic synthesis and separation purification operations.
    In addition, its appearance may be light yellow to light brown crystalline powder, and its color and morphology are also physical properties, providing an intuitive basis for identification. From the above, it can be seen that the various physical properties of 3-bromo-5- (trifluoromethyl) nitrobenzene are of great significance for applications in chemical industry, scientific research and other fields.
    What is the chemical synthesis method of 3-Bromo-5- (Trifluoromethyl) Nitrobenzene?
    The synthesis method of 3-bromo-5- (trifluoromethyl) nitrobenzene covers the priority of organic synthesis. The method usually follows the principles of organic chemistry, and selects the appropriate reaction path and reagent to form it.
    One method can be made of 3-bromo-5-trifluoromethylbenzene as the starting material. Make it encounter nitrifying reagents first, such as mixed acids (a mixture of nitric acid and sulfuric acid). In this reaction, the mixed acid has the effect of nitrification, and the nitro group (-NO 2O) replaces the hydrogen atom on the benzene ring. Because the existing substituents (bromine and trifluoromethyl) on the benzene ring have a localization effect on the reaction check point, under appropriate reaction conditions, such as temperature and time control, the target product 3-bromo-5- (trifluoromethyl) nitrobenzene can be obtained. The mechanism of this reaction is an electrophilic substitution reaction. The nitroyl cation (NO ³) generated by the mixed acid is an electrophilic reagent to attack the higher electron cloud density of the benzene ring.
    Another method, or starting from other aromatic hydrocarbons containing trifluoromethyl, can introduce nitro groups first, and then introduce bromine atoms through halogenation reaction. When halogenating, a brominating reagent, such as N-bromosuccinimide (NBS), can be used. In the presence of an initiator (such as benzoyl peroxide, etc.), a radical substitution reaction can be carried out to guide bromine atoms into a specific position of the benzene ring. After a series of reaction steps, 3-bromo-5- (trifluoromethyl) nitrobenzene can also be prepared.
    However, no matter what method, it is necessary to pay attention to the adjustment of the reaction conditions. If the temperature is too high, or side reactions occur, the product is impure; if it is too low, the reaction rate will be slow and take a long time. And the dosage ratio of the reagent must also be accurate, so as to promote the reaction to generate the target product, and the safety of the reaction and the difficulty of post-treatment must be taken into account, so that the synthesis process is both efficient and economical.
    3-Bromo-5- (Trifluoromethyl) Nitrobenzene What to watch out for when storing and transporting
    3-Bromo-5- (trifluoromethyl) nitrobenzene is an organic compound. When storing and transporting it, there are many key things to pay attention to.
    First words storage. Due to its special nature, it must be found in a cool, dry and well-ventilated place. This compound is quite sensitive to heat and humidity, and high temperature and high humidity environment can easily cause it to deteriorate, or even cause dangerous chemical reactions. The storage place should be kept away from fire and heat sources to prevent the risk of fire and explosion. Furthermore, it needs to be stored separately from oxidizing agents, reducing agents, alkalis, etc. Because of contact with it, it is very likely to trigger violent reactions. This compound may be toxic and corrosive, and it must be strictly sealed when stored to prevent leakage and endanger the safety of people and the environment.
    As for transportation, extreme caution is also required. Before transportation, make sure that the packaging is intact, choose suitable packaging materials, such as those with good sealing and leak-proof properties, and clearly mark the warning label on the outside of the package to inform everyone of its danger. During transportation, the speed of the vehicle should be slow to avoid sudden braking and turbulence to prevent the leakage of items caused by package rupture. At the same time, the transportation vehicle should also be equipped with corresponding emergency treatment equipment and protective equipment for emergencies. Transportation personnel need to be professionally trained, familiar with the characteristics of the compound and emergency treatment methods, and can respond quickly and properly in case of emergencies.
    What are the effects of 3-Bromo-5- (Trifluoromethyl) Nitrobenzene on the environment and human health?
    3-Bromo-5- (trifluoromethyl) nitrobenzene is also an organic compound. Its impact on the environment and human health cannot be ignored.
    At the end of the environment, this compound has a certain stability and is difficult to degrade naturally. If it flows into water bodies, or interferes with aquatic ecosystems due to its own chemical properties. The bromine, fluorine, nitro and other groups it contains may be toxic to aquatic organisms, affecting their growth and reproduction, and even changing the population structure. If it enters the soil, or interacts with soil components, it affects the activity and fertility of soil microorganisms and hinders the normal growth of plants.
    As for human health, it may enter the human body through respiration, skin contact, dietary intake, etc. Bromine, fluorine, nitro and other groups may have adverse effects on human cells and tissues. For example, nitro can cause protein denaturation in the human body and interfere with the normal metabolism of cells. Long-term exposure may damage the human nervous system, cause headache, dizziness, fatigue, etc.; or involve important organs such as the liver and kidneys, affect their normal function, and even have a latent risk of mutation and carcinogenesis.
    From this point of view, for 3-bromo-5- (trifluoromethyl) nitrobenzene, it must be handled with caution in the production, use and disposal of all links to reduce its harm to the environment and human health.