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3-Bromo-5-Fluorotrifluoromethylbenzene

3-Bromo-5-Fluorotrifluoromethylbenzene

Hongda Chemical

Specifications

HS Code

612434

Chemical Formula C7H3BrF4
Molar Mass 259.0 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 170 - 172 °C
Melting Point N/A
Density 1.725 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure N/A
Flash Point 64 °C
Refractive Index 1.456 - 1.458

As an accredited 3-Bromo-5-Fluorotrifluoromethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - bromo - 5 - fluorotrifluoromethylbenzene packaged in a sealed glass bottle.
Storage 3 - bromo - 5 - fluorotrifluoromethylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Avoid exposure to moisture as it may cause decomposition. Label the storage container clearly for easy identification and to ensure proper handling.
Shipping 3 - bromo - 5 - fluorotrifluoromethylbenzene is shipped in tightly sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent spills and exposure during transit.
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3-Bromo-5-Fluorotrifluoromethylbenzene 3-Bromo-5-Fluorotrifluoromethylbenzene
General Information
Historical Development
I have tried to study chemical products, today I say 3 - Bromo - 5 - Fluorotrifluoromethylbenzene. The beginning of this substance originated from the diligent exploration of the sages in the field of chemical industry. At the beginning, everyone was unclear about its characteristics, but with determination and ingenuity, they studied the physical properties and production methods.
Years have passed, and all craftsmen and bachelors have obtained good methods through trial and error. In the art of synthesis, keep improving, or adjusting temperature, or selecting agents, and strive for purity of quality. With the progress of the times, this product has gradually shown its ability in medicine, materials and other industries, and its use has become wider.
Looking at its historical development, from unknown to wide use, all rely on the unremitting efforts of predecessors. This is a page in the history of chemical industry, and it is also a lesson for future generations to explore new paths, inspiring our generation to pursue refinement in the path of chemical industry, and to expand new horizons.
Product Overview
There is a compound named 3 - Bromo - 5 - Fluorotrifluoromethylbenzene. It is an organic compound, or a colorless liquid, with a special odor. In this compound, bromo, fluoro and trifluoromethyl are connected to the benzene ring, and the unique structure gives it specific properties.
In the field of organic synthesis, it has a wide range of uses. It can be used as an intermediate and converted into other compounds through many reactions. Because it contains halogen atoms, it can participate in reactions such as nucleophilic substitution, introducing other functional groups, paving the way for the creation of new compounds.
Furthermore, due to its stable structure and fluoride-containing properties, it may have potential applications in materials science, medicinal chemistry and other fields. For example, in drug development, molecules with specific biological activities may be obtained based on their structural modification, providing new opportunities for overcoming diseases. All of this highlights its important value in chemical research and practical applications.
Physical & Chemical Properties
3-Bromo-5-fluorotrifluorotoluene is also an organic compound. Its physical and chemical properties are particularly important and affect many applications. This substance is either liquid at room temperature, and its color is observed, or it is clear and transparent. It smells and has a specific odor. Its boiling point and melting point are the keys to characterize its physical properties. The boiling point is related to its gasification temperature, and the melting point indicates the point at which its solid state and liquid state transition.
On chemical properties, because it contains halogen atoms such as bromine and fluorine, the chemical activity is considerable. Bromine atoms can participate in nucleophilic substitution reactions, while fluorine atoms have strong electronegativity, which affects the distribution of molecular electron clouds, making compounds have unique reactivity. The existence of trifluoromethyl groups also significantly changes the stability and solubility of compounds. The study of these physical and chemical properties lays a solid foundation for their application in synthesis, materials and other fields.
Technical Specifications & Labeling
Today there is a thing called 3-Bromo-5-Fluorotrifluoromethylbenzene. In the preparation of the technique, it is necessary to follow a certain rule. The material selection, when carefully selected, must be removed impurities, in order to maintain the purity of the product. The reaction equipment also needs to be clean and flawless to prevent fouling its quality.
When the reaction is carried out, temperature, duration, and material ratio are all key parameters. If the temperature is too high, the reaction will be too fast, and side effects will be feared; if it is too low, the reaction will be slow and time-consuming. The control of time cannot be ignored. If the product changes for a long time, the reaction will not be completed if it is short. The material ratio needs to be accurately calculated, and the amount is not appropriate, which affects the quantity and quality of the product.
As for the identification of the product, its characteristics should be clearly stated, such as the color state, melting point, boiling point and other physical parameters of the appearance, which should be recorded in detail. The standard of purity is also indispensable, in order to prove its high quality, it is a good product that can be used. In this way, the preparation of this product and the identification are essential.
Preparation Method
The preparation method of 3-bromo-5-fluorotrifluoromethylbenzene is related to the raw materials and production process, reaction steps and catalytic mechanism, which is the key to chemical research. To prepare this compound, the selection of raw materials is quite important. The basic compounds containing fluorine, bromine and trifluoromethyl can be used as starting materials.
The first step of its production process may be a specific substitution reaction. Under suitable reaction conditions, such as in the presence of specific solvents and catalysts, the starting material is substituted to introduce bromine atoms and fluorine atoms. The reaction steps need to be strictly controlled, and temperature and reaction time are key variables. If the temperature is too high or too low, the yield and purity of the product may be affected.
In the catalytic mechanism, specific metal catalysts or organic catalysts can be selected to reduce the activation energy of the reaction and accelerate the reaction process. For example, some transition metal catalysts can effectively guide the reaction direction and improve the selectivity of the target product. In this way, through subtle regulation of raw materials, processes, steps and catalytic mechanisms, it is expected to efficiently prepare 3-bromo-5-fluorotrifluoromethylbenzene.
Chemical Reactions & Modifications
3 - Bromo - 5 - Fluorotrifluoromethylbenzene is an important compound in organic synthesis. In chemical reactions, its chemical properties are special and can trigger many unique reactions.
Looking at the reaction, the nucleophilic substitution reaction is often the main one. However, the halogen atom activity of this compound is different from that of general halogenated aromatics due to the influence of the substituents on the benzene ring. To optimize the reaction, chemists have tried many times to adjust the reaction conditions. For example, changing the reaction temperature and choosing a suitable solvent to enhance the reaction activity.
Attempted to introduce a catalyst to improve the selectivity of the reaction. After this improvement, the reaction yield of 3 - Bromo - 5 - Fluorotrifluoromethylbenzene was improved, and the purity of the product was also improved, which laid a solid foundation for subsequent applications in organic synthesis and was of great significance to the development of organic chemistry.
Synonyms & Product Names
There is a thing today, named 3 - Bromo - 5 - Fluorotrifluoromethylbenzene. Although its name is different from that of ancient times, it is also important to find its synonymous name and business name. This thing has a wide range of uses in the field of chemistry in this world.
Reflecting on the past, although there is no such precise name, chemical things must have their aliases. As far as things are concerned, they may have synonymous names, which can express their nature and quality. A synonymous name can make people more aware of their nature and facilitate discussion and communication.
As for the business name, it is related to the circulation of trade. Different business names are given, either for marketing needs or for different recognition of things. Knowing their synonymous names and business names is beneficial for chemical research and business transactions. Scholars can use this to gain insights, and merchants can expand their business based on it, all relying on the clarification of their synonymous names and business names.
Safety & Operational Standards
3 - Bromo - 5 - Fluorotrifluoromethylbenzene Safety and Practice

Husband 3 - Bromo - 5 - Fluorotrifluoromethylbenzene is a common compound in chemical research. If you want to use it properly, you must understand its safety and operation specifications.
The first word is safe. This compound is dangerous. It may be harmful to the human body. If it comes into contact with the skin, rinse with plenty of water as soon as possible, and then wash it with an appropriate cleaning agent. If there is any discomfort, seek medical attention. If it enters the eye, rinse with plenty of water immediately, be sure to wash all corners of the eye ball, and then seek medical attention urgently. Inhaling the vapor of this compound is also harmful to health. Therefore, in the place of operation, when the ventilation is good, there are effective ventilation equipment to reduce the concentration in the air.
As for the operating specifications. When taking it, use clean and suitable equipment. Measure the exact amount without deviation, because the chemical experiment requires very strict quantity. The operation process should be in a stable place, avoid vibration and collision, and prevent it from pouring. After use, store it properly. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, and cover it or be flammable. And it should be separated from other chemicals to avoid dangerous reactions.
Furthermore, the experimenter should wear appropriate protective equipment, such as laboratory clothes, gloves, goggles, etc. This is a necessary measure to protect their own safety. Before and after operation, carefully check the utensils and equipment used to ensure that they are available normally. During operation, check the experimental situation frequently, stop if there is any abnormality, and deal with it cautiously.
All of these are the safety and operation principles of 3-Bromo-5-Fluorotrifluoromethylbenzene. Adhering to this specification can ensure the smooth operation of the experiment and protect the safety of the person.
Application Area
3-Bromo-5-fluorotrifluorotoluene is also an organic compound. Its application field is quite vast. In the field of medicinal chemistry, it can be a key intermediary to help create new drugs to fight various diseases. Drug developers, with its unique structure, hope to derive high-efficiency and low-toxicity drugs for the benefit of patients.
In the field of materials science, it is also promising. Or can participate in the synthesis of special materials, endowing materials with specific properties, such as excellent weather resistance and chemical stability. These materials can be used in high-end fields such as aerospace and electronic devices to improve the quality and performance of products.
In the field of pesticide chemistry, it may be used as a basic raw material to develop new pesticides. Make it highly effective in insecticidal and weeding effects, and have little impact on the environment, which is in line with the current development needs of green agriculture.
From this point of view, 3-bromo-5-fluorotrifluorotoluene has important application value in many fields and has broad prospects.
Research & Development
Today there is a thing, the name is 3 - Bromo - 5 - Fluorotrifluoromethylbenzene. Our business is to study its system and progress.
To study the system of this thing, we need to study various paths. Or start from a certain foundation, go through halogenation, substitution and other steps to achieve its formation. However, the rules of each step, such as temperature, pressure, and the amount of agent, need to be carefully considered. If there is a slight difference, the quantity and quality of the product will be affected.
As for its progress, this product is promising in the fields of medicine, agriculture, and materials. In medicine, it can be used to make new drugs; in agriculture, it can be used to create high-efficiency agricultural agents; in materials, or to assist in research and innovation.
We should do our best to study its system, expand its progress, and hope to benefit the world, so that this material can be used to its fullest potential and promote the prosperity of all industries.
Toxicity Research
I am committed to toxicological research, recently focusing on 3 - Bromo - 5 - Fluorotrifluoromethylbenzene this chemical. The toxicity of this substance is related to everyone's safety and cannot be ignored.
After many experiments, various organisms were used as samples to observe their reactions in detail. Looking at it, this chemical does have an impact on the biological body. At the cellular level, it can cause changes in cell activity and abnormal metabolic pathways.
Its toxic effects may enter the organism through respiratory tract or skin contact. After entering the body, it interferes with normal physiological functions and damages organ functions. Although the experimental samples are limited at present, it has shown its potential harm.
In the future, we will collect extensive data, study its mechanism of action, and strive to clarify the overall toxicity of this chemical, so as to provide a solid basis for protection and treatment, and protect all living beings from its harm.
Future Prospects
I have tried to devote myself to chemical substances, and recently focused on 3 - Bromo - 5 - Fluorotrifluoromethylbenzene. This substance is unique in nature and has potential uses in the field of chemistry.
Looking at its future development, I am full of longing. First, in the way of pharmaceutical research and development, it may become a key raw material to help create new medicines and solve the pain of the world. Second, in the way of materials science, it is expected that through ingenious design and synthesis, materials with strange properties will be produced, which will add wings to the innovation of various industries.
Although there may be thorns in the road ahead, I hold a strong heart and am willing to devote what I have learned to explore its endless mysteries. With unremitting research, I hope to help this substance shine in the future, for the well-being of the world, and for the progress of chemistry.
Where to Buy 3-Bromo-5-Fluorotrifluoromethylbenzene in China?
As a trusted 3-Bromo-5-Fluorotrifluoromethylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo-5-Fluorotrifluoromethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Bromo-5-Fluorotrifluoromethylbenzene?
3-Bromo-5-fluorotrifluoromethylbenzene is also an organic compound. It has a wide range of uses and is a key raw material in the field of organic synthesis.
First, it is often used as a starting material in the process of pharmaceutical synthesis. Due to its unique structure, specific functional groups can be introduced through many chemical reactions, and then a molecular structure with biological activity can be constructed. Taking the synthesis of an anti-cancer drug as an example, 3-bromo-5-fluorotrifluoromethylbenzene can be combined with other heterocyclic compounds containing nitrogen and oxygen through a series of steps such as halogenation reaction and nucleophilic substitution reaction to shape a novel compound structure that inhibits the growth of cancer cells.
Second, in the field of materials science, it also has important functions. Because it contains fluorine atoms, it can endow materials with special properties. For example, when preparing high-performance fluoropolymer materials, 3-bromo-5-fluorotrifluoromethylbenzene can participate in the polymerization reaction as a comonomer, and the resulting polymer often has excellent chemical resistance, weather resistance and low surface energy. These properties make these polymers promising in industries such as coatings and plastics, such as the manufacture of coatings with excellent outdoor durability, or the manufacture of plastic products that need to resist harsh chemical environments.
Third, in the field of pesticide synthesis, it is also indispensable. Through a reasonable reaction path, it is converted into pesticide ingredients with insecticidal, bactericidal or herbicidal activities. Due to its special electronic effects and spatial structure, pesticide molecules can better bind to specific receptors in target organisms, improve the activity and selectivity of pesticides, and provide a powerful tool for pest control in agricultural production.
All of these show that 3-bromo-5-fluorotrifluoromethylbenzene has crucial uses in many fields such as organic synthesis, medicine, materials, pesticides, etc. It is an important substance in the field of organic chemistry.
What are 3-Bromo-5-Fluorotrifluoromethylbenzene synthesis methods?
In the past, craftsmen used to follow various paths to prepare 3-bromo-5-fluorotrifluoromethylbenzene. First, fluoroaromatic hydrocarbons are often used as the starting material, and bromine atoms are introduced by electrophilic substitution. Among them, suitable brominating reagents, such as bromine, N-bromosuccinimide, etc. Under specific reaction conditions, such as the presence of bromine atoms in a catalyst or in a suitable solvent environment, the bromine atoms precisely fall at specific positions of aromatic hydrocarbons, that is, the bromine-containing intermediates of the target molecule are obtained.
Second, halogenation reactions are also carried out based on aromatic hydrocarbons containing trifluoromethyl. In this process, the reaction temperature, the proportion of reactants and the reaction time need to be carefully regulated. If the temperature is too high, it is easy to cause a cluster of side reactions; if the ratio is out of balance, the product will be impure.
In addition, or first construct an intermediate containing trifluoromethyl and bromine, and then borrow nucleophilic substitution to introduce fluorine atoms. In this case, it is necessary to choose a nucleophilic reagent with appropriate activity, and pay attention to the optimization of reaction conditions, such as the nature of the solvent, the type and dosage of the base, etc., all of which are related to the success or failure of the reaction and the yield of the product.
The method of preparing 3-bromo-5-fluorotrifluoromethylbenzene is not the same, and the craftsman needs to choose the route and fine-tune the conditions according to the materials in hand, the reaction equipment
What are the physical properties of 3-Bromo-5-Fluorotrifluoromethylbenzene?
3-Bromo-5-fluorotrifluoromethylbenzene, this is an organic compound, its physical properties are particularly important, and it is widely used in the field of organic synthesis.
Looking at its properties, under room temperature and pressure, it is mostly a colorless to light yellow transparent liquid. This color property is convenient for visual preliminary identification in experiments and production processes. It has a specific odor. Although there is no literature detailing the exact odor characteristics, it should be carefully paid attention to when operating and using it, because its odor may suggest potential danger.
Talking about the boiling point, it is between 150 and 160 ° C. The physical constant of boiling point is of great significance for the separation and purification of compounds. In separation operations such as distillation, 3-bromo-5-fluorotrifluoromethylbenzene can be effectively separated from the mixture according to the difference in boiling point.
Its melting point is also a key physical property, but the exact value is not detailed in the literature. The determination of the melting point can assist in the identification of the purity of the compound. The melting point of the pure substance is fixed. If it contains impurities, the melting point decreases and the melting range becomes wider.
The density of 3-bromo-5-fluorotrifluoromethylbenzene is about 1.8 g/cm ³. This density data is helpful for estimating its location and distribution in the system when operations such as liquid mixing and stratification are involved.
In terms of solubility, the compound is insoluble in water, which is related to the polarity of water and its own structure. Its molecule contains halogen atoms and trifluoromethyl groups, resulting in a large difference in polarity from water, so it is insoluble. However, it is soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. This solubility characteristic provides a basis for the selection of appropriate reaction solvents in organic synthesis, which can fully contact the reactants and improve the reaction efficiency.
In addition, although its physical properties such as vapor pressure are rare, they also affect its existence form and volatilization degree under different temperatures and pressures. It needs to be considered when storing and using.
What are the chemical properties of 3-Bromo-5-Fluorotrifluoromethylbenzene?
3-Bromo-5-fluoro-trifluoromethylbenzene is an organic compound. It has unique chemical properties and is widely used in the field of organic synthesis.
From the perspective of the properties of halogenated aromatics, bromine atoms are highly active and can react with many nucleophilic reagents such as alkoxides and amines through nucleophilic substitution reactions. This reaction can introduce different functional groups, laying the foundation for the construction of complex organic molecules. For example, when reacted with alkoxides, corresponding ether compounds can be formed; when reacted with amines, nitrogen-containing derivatives can be formed.
The presence of fluorine atoms also affects its properties. Fluorine atoms are highly electronegative, which changes the distribution of molecular electron clouds, enhances molecular polarity, and affects the physical and chemical properties of compounds. And the introduction of fluorine atoms often improves the stability and biological activity of compounds, and has been paid much attention in the synthesis of medicines and pesticides.
Trifluoromethyl has strong electron-absorbing properties, which significantly affects the electron cloud density of the benzene ring and changes the activity of electrophilic substitution reactions on the benzene ring. Usually, electrophilic substitution reactions are more likely to occur at relatively high electron cloud densities. At the same time, trifluoromethyl has a great impact on the lipid solubility of compounds, which can improve the absorption, distribution and metabolism of compounds in vivo.
In addition, 3-bromo-5-fluorotrifluoromethylbenzene has relatively good thermal stability. Under moderate heating conditions, the structure will not be easily decomposed, which is conducive to participating in organic synthesis reactions under various reaction conditions, providing the possibility for the synthesis Overall, its unique chemical properties provide a rich space for the research and application of organic synthetic chemistry.
What is the price range of 3-Bromo-5-Fluorotrifluoromethylbenzene in the market?
The price of 3 - Bromo - 5 - Fluorotrifluoromethylbenzene in the market is difficult to determine. The price often changes due to many reasons, such as the abundance of production sources, the difficulty of preparation, and the amount of purchase.
In the past, if the preparation of this product was difficult and the raw materials were rare, its price would be high. The production source is wide and the preparation method is refined, resulting in an increase in output, the price may fall. There are many buyers, and the supply exceeds the demand, and the price also increases; if the market oversupply, the price will decrease.
And the place of trade is different, and the price is also different. In bustling commercial ports, the logistics is smooth, the competition is fierce, and the price is relatively flat; in remote places, the transportation is inconvenient, the cost increases, and the price may be slightly higher.
As far as I know, the price per gram may range from tens of yuan to hundreds of yuan. However, this is only a rough figure. The actual price must be consulted by a merchant specializing in chemical materials to obtain a definite figure. And the market conditions are changing rapidly, and the price also changes accordingly. Therefore, to seek an accurate price, it is advisable to consult the city in time.