3-Bromo-4-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code	447913
Name	3-Bromo-4-Fluoronitrobenzene
Chemical Formula	C6H3BrFNO2
Molar Mass	220.00 g/mol
Appearance	Yellow to brown solid
Melting Point	37 - 41 °C
Boiling Point	236 - 237 °C
Density	1.804 g/cm³
Solubility In Water	Insoluble
Flash Point	113 °C
Logp	2.79

As an accredited 3-Bromo-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 3 - bromo - 4 - fluoronitrobenzene packaged in a sealed, corrosion - resistant bottle.
Storage	Store 3 - bromo - 4 - fluoronitrobenzene in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Since it is a chemical, segregate it from incompatible substances like oxidizing agents, reducing agents, and bases to prevent potential reactions.
Shipping	3 - bromo - 4 - fluoronitrobenzene is a chemical. Ship it in well - sealed containers, following regulations for hazardous chemicals. Ensure proper labeling, and transport with carriers experienced in handling such substances to prevent spills and ensure safety.

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General Information

Historical Development

The industry of chemical industry is changing with each passing day, and all kinds of products have their own sources. In today's words 3 - Bromo - 4 - Fluoronitrobenzene, its birth can also be traced.
At the beginning, chemists studied physical properties and explored methods of synthesis. After several years of spring and autumn, after countless attempts, they were able to make a way. Or in exquisite instruments, make all kinds of raw materials interact according to specific rules. Or temperature control, or pressure regulation, repeated consideration, and unremitting exploration.
In the process of its development, chemists strive for excellence, improve processes, improve yields, and optimize quality. Make this product, from the beginning to maturity, and its application is also gradually widening. In the fields of medicine and materials, it has been used to help the industry move forward. This is a summary of the historical development of 3-Bromo-4-Fluoronitrobenzene.

Product Overview

3-Bromo-4-fluoronitrobenzene is an organic compound. It is crystalline in shape and often light yellow in color. This substance has unique chemical properties and is widely used in the field of organic synthesis.
Its preparation method involves many fine chemical reactions. It can be prepared from suitable raw materials through halogenation, nitrification and other steps. The reaction process requires strict control of conditions, such as temperature, pH, etc., to obtain high-purity products.
In industrial applications, 3-bromo-4-fluoronitrobenzene is often used as an intermediate for the synthesis of many drugs, pesticides and materials. Due to its special structure, the product is endowed with unique properties.
However, this product also needs to be properly stored because it may be toxic and dangerous. When handling, safety procedures must be followed to prevent harm to people and the environment.

Physical & Chemical Properties

3 - Bromo - 4 - Fluoronitrobenzene, also an organic compound. Its physical and chemical properties are worth studying. Looking at its color, it is often colorless to light yellow, like the first melting of glaze, and the luster is slightly transparent. Smell it, it has a special smell, like ancient wood hidden and secluded, with a unique charm.
On its melting point, it is about [X] ° C, just like ice melts gradually when it meets temperature. At this specific degree, the shape begins to change. The boiling point is at [X] ° C. When it is hot, like clouds evaporating, the material turns into a gaseous state.
Its solubility is soluble in organic solvents, such as fish in water; in water, it is sparse and difficult to blend, just like oil and water, and it is distinct. The chemical properties of this substance are also active, and the bromine, fluorine, and nitro groups on the benzene ring are all important parts of the reaction, which can react with various reagents. In case of nucleophiles, it can lead to substitution and open the door to the generation of new compounds. It has a wide range of uses in the field of organic synthesis.

Technical Specifications & Labeling

There are chemical products 3 - Bromo - 4 - Fluoronitrobenzene today, which is crucial to its technical specifications and identification (product parameters). Its technical specifications need to be accurate and accurate, which is related to the quality and use of the product. In terms of composition, the proportion and purity of bromine (Bromo), fluorine (Fluoro) and nitro (nitro) must meet specific standards to ensure their chemical stability.
Labeling (product parameters) cannot be ignored. Clear labeling of names, chemical formulas, molecular weights, etc., can help users clarify their characteristics. And it should contain safety labels to show its toxicity, flammability, etc., to warn everyone to use it safely. The production, circulation and application of 3-Bromo-4-Fluoronitrobenzene are both critical.

Preparation Method

The raw materials and production process, reaction steps and catalytic mechanism of 3-Bromo-4-Fluoronitrobenzene are crucial. Fluorobenzene is taken as the initial raw material and nitrified to introduce nitro groups. In this step, concentrated nitric acid and concentrated sulfuric acid are used as reaction reagents. At a specific temperature, the two work ingeniously to obtain 4-fluoronitrobenzene.
Then, 4-fluoronitrobenzene and bromine are brominated under the catalysis of iron powder. Iron powder promotes bromine polarization, enhances its reactivity, and introduces bromine atoms at a specific position in the benzene ring, resulting in 3-Bromo-4-Fluoronitrobenzene. During the reaction process, the temperature, reagent ratio and reaction time need to be carefully controlled to improve the purity and yield of the product. In this way, through this orderly step, the target product is skillfully prepared.

Chemical Reactions & Modifications

3 - Bromo - 4 - Fluoronitrobenzene is also an organic compound. Its chemical reaction is related to the chemical industry and is quite important.
Looking at its reaction, it is often based on the characteristics of nitro and halogen atoms. Nitro has strong electron absorption, which reduces the density of the electron cloud of the benzene ring. In the electrophilic substitution reaction, the activity of the ortho-para-site is reduced, and the meta-site is relatively vulnerable to attack. Although bromine and fluorohalogen atoms also affect the distribution of the electron cloud of the benzene ring, they have their own properties. Bromine atoms are large in size and have significant spatial effects; fluorine atoms have high electronegativity and prominent electronic effects.
In order to optimize their reaction and modification, chemists often explore new ways. Or adjust the temperature, pressure, and solvent of the reaction to find the best environment; or introduce other groups to change the properties of the molecule and make it more active and selective for specific reactions. This unremitting exploration aims to obtain an efficient and specific synthesis method, so that 3-Bromo-4-Fluoronitrobenzene can be used in medicine, materials and other fields.

Synonyms & Product Names

3 - Bromo - 4 - Fluoronitrobenzene is also a chemical raw material. Its synonymous name and trade name are also important in the industry.
Consider this substance, the synonymous name, or according to its chemical structure characteristics. For example, in the genus of halogenated nitrobenzene, because it contains bromine (Bromo), fluorine (Fluoro) atoms at specific positions in the benzene ring, or other names, it is inseparable from the essence of its chemical composition.
As for the trade name, it depends on the manufacturer's marketing activities and product characteristics. Or to highlight its high purity, or to show its specific use.
Today's chemical research has been explored in 3 - Bromo - 4 - Fluoronitrobenzene. The clarity of its synonyms and trade names helps the academic community and industry to communicate, and is indispensable in R & D, production, and trade. Therefore, identifying its synonyms and trade names is also an important task for chemical research and industrial development.

Safety & Operational Standards

3 - Bromo - 4 - Fluoronitrobenzene Safety Production and Operation Specifications
Fu 3 - Bromo - 4 - Fluoronitrobenzene, also a chemical substance. Its preparation, storage and use should follow strict safety and operation specifications to prevent accidents and ensure the safety of personnel and the environment.
At the beginning of preparation, all utensils must be clean and dry. The reaction vessel used should be resistant to the temperature and pressure of the reaction, and sealed without leakage. When feeding, each reactant should be added slowly according to the precise amount, and should not be rushed to prevent overreaction. The speed of stirring should also be moderate, so that the reaction is uniform and does not cause local overheating or uneven reaction.
When the reaction is going on, closely observe the change of temperature and pressure. Set up a temperature control device to keep the reaction temperature in a suitable range. If the temperature is too high, apply the method of cooling quickly to prevent explosion boiling or side reactions. If the pressure is abnormal, the sealing and reaction state of the quick check device should not be careless.
When storing, choose a cool, dry and well-ventilated place. Keep it in a sealed container to avoid contact with water, air and other easily reactive substances. Put a clear label on it, write its name, nature and precautions to prevent misuse.
When taking it, it is necessary to wear protective equipment, such as gloves, goggles, gas masks, etc. Operate in the fume hood, so that the volatile gas can be discharged in time without endangering the person. Measure the equipment and use it immediately to prevent impurities from mixing in.
The disposal of waste should not be neglected. According to relevant regulations, collect it by category, and dispose of it with qualified parties. Do not discard it at will to avoid polluting the environment.
In short, everything in 3 - Bromo - 4 - Fluoronitrobenzene should be safe and follow the rules of operation to ensure that everything goes smoothly and there is no trouble.

Application Area

3-Bromo-4-fluoronitrobenzene is also an organic compound. Its application field is quite extensive. In the process of pharmaceutical synthesis, it is often a key intermediary. With this material, many special drugs can be made to cure various diseases.
In the field of pesticide creation, it also has its place. It can obtain high-efficiency and low-toxicity pesticides through specific reactions, protect the growth of crops, and drive pests away from fields.
And in the field of materials science, 3-bromo-4-fluoronitrobenzene can be used as a precursor to prepare materials with special properties, or with excellent electrical conductivity and optical properties, which can contribute to the manufacture of electronic and optical devices and promote their progress and development.

Research & Development

In the field of chemical industry, the substances are complicated and new ones are produced. Today there is 3-Bromo-4-Fluoronitrobenzene, which is also a compound. In my research, its significance is extraordinary.
I began to observe its structure and explore its characteristics. After many experiments, I learned its reaction mechanism. At the beginning, I tried various synthesis methods, but encountered many difficulties. However, I worked tirelessly to study, and finally found a feasible path.
In terms of reaction conditions, temperature, pressure, and the ratio of reagents, all of them were explored in detail. Strive for precision to improve the yield. Every breakthrough is a joy.
Looking at its application prospects, it is expected to show its skills in the fields of medicine and materials. I will study it diligently, hoping to make it fully effective and contribute to the development of the chemical industry, in order to achieve unparalleled success.

Toxicity Research

The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today, 3-Bromo-4-Fluoronitrobenzene is used to discuss this substance.
This substance is toxic and harmful to the body. Taste all experiments. If you accidentally touch it or enter the skin, it will be redness and itching in the light, and ulceration in the severe will be difficult to heal. If you breathe into the lungs, it will damage the function of the lungs, cause shortness of breath and cough, and the lung will be sick for a long time.
The reason for its toxicity is due to the bromine, fluorine, and nitro groups in the structure. Bromine and fluorine are active and easily react with biomolecules in the body, disturbing their normalization. Nitro has strong oxidizing properties, breaks the cell structure, and disrupts the order of metabolism.
Those who study this substance must strictly abide by the procedures, prepare protective equipment, and check the safety of the environment. In the development of chemical industry in China, although the research of poisons is necessary, life safety is the first priority, and harm should not be forgotten because of profit. It should be done with caution to ensure foolproof.

Future Prospects

Husband 3 - Bromo - 4 - Fluoronitrobenzene, the thing of transformation. Today's future prospects, there is no way to do it. In the field of exploration, it is necessary to introduce more people to study its properties and reverse the theory, so as to expand the knowledge of the field of transformation. Work-making, or there may be a refined way to improve its efficiency and reduce its cost, so that this product can be used in the industry. Domain, or the foundation of new research, to help people save lives. Material science, or its characteristics, to create new materials to meet the needs of each. Moreover, 3 - Bromo - 4 - Fluoronitrobenzene is not yet available, if it is a star, it must be used in the field of transformation and phase, and the shining light, the possibility of development and limitation.

Where to Buy 3-Bromo-4-Fluoronitrobenzene in China?

As a trusted 3-Bromo-4-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Bromo-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-Bromo-4-Fluoronitrobenzene?

3-Bromo-4-fluoronitrobenzene is an important intermediate in the field of organic synthesis. It has a wide range of uses and plays a key role in the preparation of many fine chemicals.
First, it plays a pivotal role in the field of drug synthesis. Because the design and construction of drug molecules often require the introduction of specific functional groups, and the bromine, fluorine and nitro functional groups of 3-bromo-4-fluoronitrobenzene can be skillfully converted into other required groups through a series of chemical reactions, thereby constructing drug molecules with complex structures and specific pharmacological activities. For example, through nucleophilic substitution reactions, bromine or fluorine atoms can be replaced with biologically active amine groups, hydroxyl groups and other groups, laying the foundation for the development of new drugs.
Second, in the field of materials science, 3-bromo-4-fluoronitrobenzene also plays a key role. In the preparation of high-performance organic optoelectronic materials, the structure and electronic properties of molecules need to be precisely regulated. The unique structure of this compound allows it to participate in the construction of organic conjugated systems, endowing the materials with unique optical and electrical properties. For example, by introducing it into the polymer skeleton through an appropriate reaction, it is expected to improve the charge transport capacity and fluorescence quantum yield of the material, which can be applied to frontier materials such as organic Light Emitting Diode (OLED) and organic solar cells.
Third, in the synthesis of pesticides, 3-bromo-4-fluoronitrobenzene is also very useful. The creation of pesticides requires the development of compounds with high efficiency, low toxicity and environmental friendliness. Using it as a raw material, pesticide ingredients with specific insecticidal, bactericidal or herbicidal activities can be synthesized through multi-step reactions. The functional groups in its structure can interact with specific receptors or enzymes in the target organism, exhibiting excellent biological activity. Overall, 3-bromo-4-fluoronitrobenzene, with its unique structure and rich reactivity, has irreplaceable and important uses in many fields such as drugs, materials and pesticides, promoting the continuous development and innovation of related industries.

What are 3-Bromo-4-Fluoronitrobenzene synthesis methods?

There are various methods for the synthesis of 3-bromo-4-fluoronitrobenzene. The most common one is to use 4-fluoronitrobenzene as the starting material and prepare it by bromination reaction. In this process, a suitable brominating reagent, such as liquid bromine, is required, and it is often accompanied by a catalyst, such as iron powder or iron tribromide. During the reaction, in a suitable reaction vessel, control the appropriate temperature and reaction time. Liquid bromine is added dropwise to the system containing 4-fluoronitrobenzene and catalyst, stirred evenly, and maintained at a certain temperature, usually in the range of low temperature to medium temperature. When the reaction number is completed, after separation and purification steps, such as extraction, distillation, recrystallization, etc., the target product 3-bromo-4-fluoronitrobenzene can be obtained.
Furthermore, 3-bromo-4-fluoroaniline can also be used as a raw material and obtained by diazotization and nitrification. First, 3-bromo-4-fluoroaniline is diazotized with an appropriate amount of sodium nitrite and inorganic acids, such as hydrochloric acid or sulfuric acid, at low temperature to generate diazonium salts. After that, the diazonium salt is reacted with nitrifying reagents, such as mixed acids of nitric acid and sulfuric acid, under specific conditions to convert the amino group into nitro group, and then through subsequent treatment, such as neutralization, separation, purification, etc., the final 3-bromo-4-fluoronitrobenzene is obtained.
Or there are other synthesis paths, but the above two are more common methods. Each method has its own advantages and disadvantages, and it needs to be used according to the actual situation, such as the availability of raw materials, cost, and purity requirements of the product.

What are the physical properties of 3-Bromo-4-Fluoronitrobenzene?

3-Bromo-4-fluoronitrobenzene is a kind of organic compound. It has specific physical properties, which are hereby described in detail by you.
First of all, its appearance is often white to light yellow crystalline powder at room temperature. Looking at it, the texture is fine, which is its unobservable appearance.
When it comes to the melting point, it is about 58-62 ° C. This temperature range is critical for the phase transition of the substance. When the ambient temperature gradually rises to near the melting point, the substance slowly melts from the solid state to the liquid state. This phase transition process follows the laws of physics and reflects the characteristics of its intermolecular forces.
In addition to its solubility, it has a certain solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc. Due to the specific interactions between the molecular structure of the compound and the molecules of the organic solvent, such as van der Waals force, hydrogen bonding, etc., it can be dispersed in the solvent to form a uniform mixed system. However, in water, its solubility is very small, and it is difficult to form an effective interaction due to the large difference between the polarity of the molecule and the polarity of the water molecule. Therefore, it is difficult to dissolve in water.
has its density. Although there is no exact constant value for reporting, according to its molecular composition and the characteristics of similar compounds, its density is heavier than that of water. This property is important to consider when it comes to operations such as liquid-liquid separation.
Its vapor pressure is very low at room temperature, which means that the substance evaporates slowly at room temperature. This is because of the strong intermolecular force, the tendency of molecules to escape from the liquid phase surface and enter the gas phase is small, so it is more difficult to volatilize and dissipate into the air under normal conditions.
In summary, the physical properties of 3-bromo-4-fluoronitrobenzene, such as appearance, melting point, solubility, density, and vapor pressure, are closely related to its molecular structure, and are used in many fields such as organic synthesis and chemical production. Due to its unique physical properties, it plays an important role and provides a basic basis for related research and applications.

What are 3-Bromo-4-Fluoronitrobenzene storage conditions?

3-Bromo-4-fluoronitrobenzene is also an organic compound. Its storage conditions are related to many important items, as detailed below.
The first thing to pay attention to is the temperature. It should be stored in a cool place. If the temperature is too high, it will easily cause its chemical properties to be unstable, or cause changes such as decomposition. Because high temperature can increase molecular activity, the originally stable structure will change. Therefore, in general, it is appropriate to not exceed 30 ° C, so that it can maintain its inherent characteristics for a considerable period of time.
Times and humidity. Moisture has a significant impact on it. This compound may react in water or high humidity environments, or react such as hydrolysis, which will damage its purity and quality. Therefore, it should be placed in a dry place. If the humidity can be controlled at 40% - 60%, it is better.
Furthermore, the storage place must be well ventilated. Due to 3-bromo-4-fluoronitrobenzene or volatilization of harmful gases, if the ventilation is not smooth, the gas will accumulate, one will endanger the safety of the storage environment, and the other may affect the properties of the compound itself. Good ventilation can disperse harmful gases in time and ensure the stability of the storage environment.
In addition, this material has certain toxicity and corrosiveness, and it must be separated from oxidizing agents, reducing agents, acids, alkalis and other substances when stored. When these are encountered, it is easy to cause violent chemical reactions, causing fire, explosion and other dangers. It must be stored in a special container. The container must be corrosion-resistant and well sealed to prevent leakage and endanger the surroundings.
During storage, it should also be checked regularly. Check whether its appearance has changed and whether its purity has decreased. If there is any abnormality, take measures quickly to ensure its quality. In this way, it is also possible to properly store 3-bromo-4-fluoronitrobenzene.

What is the price range of 3-Bromo-4-Fluoronitrobenzene in the market?

The price range of 3-bromo-4-fluoronitrobenzene is difficult to determine in the market. The price of this compound often changes for many reasons.
The first to bear the brunt is the cost of production. The price of raw materials, such as bromide, fluoride and nitrobenzene, is directly related to the manufacturing cost of 3-bromo-4-fluoronitrobenzene. If the price of raw materials increases, the price of this compound will also increase; conversely, if the price of raw materials decreases, the price may decline. Furthermore, the difficulty of the production process also affects. If the preparation method is complicated, requires multiple processes, takes a long time and has high technical requirements, the cost will increase, and the price will also rise accordingly.
The situation of supply and demand in the market is also the key. If there are many people who need it, but the amount of production is small, and the supply is in short supply, the price will rise; if the supply exceeds the demand, the merchant will sell the goods, or reduce the price in order to sell. In addition, different manufacturers have different pricing strategies. Large manufacturers may have controllable costs due to economies of scale, and the price may be slightly lower; small manufacturers have higher costs, and the price may be slightly higher.
Trade policies, transportation costs, etc., can also affect the price. Changes in tariffs, the distance and mode of transportation can all increase or decrease costs, which in turn affects the price.
In short, in order to know the exact price range of 3-bromo-4-fluoronitrobenzene, it is necessary to observe the raw material market, supply and demand dynamics and quotations of various manufacturers in real time, so as to obtain a more accurate price range. However, at present, it is difficult to say the specific price range.