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3-Bromo-4,5-Difluoronitrobenzene

3-Bromo-4,5-Difluoronitrobenzene

Hongda Chemical

Specifications

HS Code

758336

Chemical Formula C6H2BrF2NO2
Molar Mass 255.986 g/mol
Appearance Solid (Typical appearance, may vary)
Solubility In Water Insoluble (Aromatic nitro - halide compounds are generally insoluble in water)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (Aromatic compounds usually show solubility in such solvents)
Hazard Class Harmful (Based on general properties of halogen - nitro aromatic compounds, may cause harm if swallowed, inhaled or in contact with skin)

As an accredited 3-Bromo-4,5-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - bromo - 4,5 - difluoronitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 3 - bromo - 4,5 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly closed container made of corrosion - resistant material, such as glass or certain plastics, to prevent leakage and exposure to air or moisture, which could potentially lead to decomposition or reactivity issues.
Shipping 3 - bromo - 4,5 - difluoronitrobenzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. Use properly labeled, leak - proof containers. Ensure proper handling to prevent spills during transit.
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3-Bromo-4,5-Difluoronitrobenzene 3-Bromo-4,5-Difluoronitrobenzene
General Information
Historical Development
3 - Bromo - 4,5 - Difluoronitrobenzene, the product of chemistry. Observe the evolution of chemical technology, the birth of this product, after all kinds of research. In the past, scholars explored the field of chemistry, and at first only knew a little about the nature of elements and the method of chemical synthesis. Years have passed, skills have improved, instruments have become new, and analysis has improved. People are more and more interested in halogenated nitrobenzene compounds, and their structure and reactivity have been studied. After repeated tests and deliberation, the synthesis path has gradually become clear, and the conditions have gradually improved, so that 3 - Bromo - 4,5 - Difluoronitrobenzene can exist. The generation of this product was not achieved overnight, but the result of the efforts of chemists of all dynasties and their unremitting pursuit of chemical mysteries.
Product Overview
Today there is a product called 3-Bromo-4,5-Difluoronitrobenzene. It is a key raw material for organic synthesis and has a wide range of uses in the fields of medicine and pesticides.
Looking at its shape, it is white to light yellow crystalline powder with stable properties. Its molecular structure is unique, containing functional groups such as bromine (Bromo), fluorine (Fluoro) and nitro (nitro). Bromine atoms endow it with specific reactivity, which can lead to reactions such as nucleophilic substitution; fluorine atoms enhance its lipid solubility and stability, which have a profound impact on biological activity; nitro groups provide the possibility for it to participate in various reactions.
The preparation of this product often goes through a specific organic reaction path, and the reaction conditions, such as temperature, pH and reactant ratio, need to be carefully controlled to achieve high yield and purity. Due to its importance in many fields, the research on it continues to deepen, hoping to expand its application, improve its performance, and benefit the development of related industries.
Physical & Chemical Properties
3 - Bromo - 4,5 - Difluoronitrobenzene is an organic compound. Its physical properties are unique. It is mostly solid at room temperature and has a specific melting point and boiling point. The melting point makes this substance melt from solid to liquid at a specific temperature, and the boiling point determines that it changes from liquid to gaseous at a specific temperature.
From the perspective of chemical properties, the functional groups of bromine, fluorine and nitro in this compound give it active chemical activity. Nitro has strong electron absorption, which affects the electron cloud density of the benzene ring, making the benzene ring more prone to nucleophilic substitution. Bromine and fluorine atoms also participate in many chemical reactions, either as leaving groups or participating in the construction of new chemical bonds, which have important applications in the field of organic synthesis. Due to its delicate balance between chemical activity and stability, it has attracted the attention of organic synthesis chemists and is widely used in fine chemicals, drug development, and other fields.
Technical Specifications & Labeling
3 - Bromo - 4,5 - Difluoronitrobenzene is an important chemical product. Its technical specifications and identification (product parameters) are related to many key elements. The appearance of this product needs to be pure and free of impurities, and the color should be normal. The purity must be of the highest standard, and the impurity content should be strictly limited. Regarding its physical properties, data such as melting point and boiling point need to be accurately measured and recorded to ensure that the quality is important. Chemical properties cannot be ignored, and reactivity, stability, etc. are all key parameters. In terms of identification, product names, ingredients, danger warnings and other information should be clear and clear to ensure that users can accurately recognize and use them safely. Strict control of technical specifications and labels is of vital significance in the production, circulation and application of this product, which can ensure its quality and safety.
Preparation Method
This 3 - Bromo - 4,5 - Difluoronitrobenzene is prepared as raw materials. An appropriate amount of fluorobenzene is taken and brominated with bromine to obtain bromofluorobenzene. Complex with mixed acid nitration, temperature control and timing, then 3 - Bromo - 4,5 - Difluoronitrobenzene crude product.
The process is as follows: At the time of bromination, fluorobenzene and bromine are added to the reaction kettle in a certain ratio, a catalyst is added, moderate temperature is added, and stirring is required. On the occasion of nitration, crude bromofluorobenzene is added to the mixed acid, which is slowly heated to stabilize the reaction conditions and make the nitro group suitable.
After the reaction is completed, it is purified by distillation and extraction. Distillate first to remove the low boiling matter; then extract, extract the product with a suitable solvent, separate the phase, dry, and re-distill to obtain the pure product. Control the whole process of this preparation, from raw materials, reaction to refining, all follow the rules to obtain good products.
Chemical Reactions & Modifications
The study of the reaction and denaturation of 3 - Bromo - 4,5 - Difluoronitrobenzene is an important issue in today's chemical research.
Looking at this compound, the positions of bromine, fluorine and nitro groups show unique properties in the chemical reaction. Bromine can open the way of nucleophilic substitution, and with its activity, it can lead other groups into its positions, causing changes in molecular structure. Fluorine atoms, because of their strong electronegativity, can stabilize molecules at the same time, or change the power and direction of the reaction. Nitro groups are often the conductors of reaction activity, and can participate in reduction, electrophilicity, etc.
To improve its properties, you can try to adjust the conditions of reaction, such as temperature, pressure and catalytic agents. Raise the temperature, or promote the speed of reaction, but also need to prevent the generation of side reactions. Choose the appropriate catalysis, or the direction of the reaction, so that the rate and purity of the product can rise. And the nature of the medium is also related to whether the reaction is completed, and the polar nature agent may be beneficial to the dissociation and nucleophilic response.
The study of chemical reaction and denaturation is actually a journey to find new substances and new paths, hoping to obtain new results, in order to benefit the progress of chemistry and various industries.
Synonyms & Product Names
Today there is a thing called 3 - Bromo - 4, 5 - Difluoronitrobenzene. There are many different names because of the field of chemical industry, and the names depend on each other. Or from its nature, or according to its structure, various other names are generated.
This substance, in terms of chemistry, has a delicate structure. Bromo, fluoro and nitro are combined on the benzene ring. Because of its specific structure, it is used in many fields such as chemical preparation and pharmaceutical research and development.
The world is in the city, and the name of its goods is also different. However, no matter what the name is, its essence is the same. All of them are valued by researchers. They explore their properties and expand their uses on the experimental platform, with the aim of enhancing human well-being and promoting the entry of chemical industry.
Safety & Operational Standards
3 - Bromo - 4,5 - Difluoronitrobenzene Safety and Operating Specifications
Fu 3 - Bromo - 4,5 - Difluoronitrobenzene, is an important raw material for organic synthesis, and is widely used in medicine, pesticides and other fields. However, it is dangerous, so when operating, strictly abide by safety and operating standards to ensure personal and environmental safety.
#1. Physical and chemical properties
This substance is solid and has a special odor. Its melting point, boiling point and other physical properties are fixed. In chemical research and production practice, detailed attention should be paid to clarify its characteristics and use it reasonably.
#2. Safety hazards
1. ** Health Hazards **: If inadvertently touching the skin, it can cause skin irritation, redness, swelling, and pain. Eye damage, or visual impairment. Inhalation of its dust, irritating the respiratory tract, causing cough, asthma, and even life-threatening. Long-term exposure, or damage to liver, kidney and other organs, affecting physical health.
2. ** Environmental Hazards **: Refractable in the environment, can cause soil and water pollution. If it flows into the ecosystem, or enriches through the food chain, it endangers biodiversity.
#3. Operating Specifications
1. ** Operating Environment **: It should be operated in a well-ventilated place, and local exhaust devices should be installed to expel volatile air in time. The operating table should be neat and free of debris, so that it can be operated and cleaned up.
2. ** Personnel protection **: Operators must wear protective clothing, wear protective gloves, and choose the appropriate material to prevent penetration. Wear protective glasses or masks to protect your eyes from damage. When operating, wear a gas mask and choose the appropriate type according to the degree of harm.
3. ** Operation process **: Use this object, use clean and dry appliances, and use it accurately according to the required amount. Do not cause waste and danger. When stirring, use a suitable mixer to control the speed and prevent splashes. Heating needs to be temperature controlled, and choose the appropriate heating method to prevent decomposition or explosion due to overheating.
4. ** Emergency treatment **: If the skin comes into contact, rinse with plenty of water immediately and seek medical attention. Immediately open the eyelids when entering the eyes, rinse with water, and send to the hospital. Inhalers, move to a place with fresh air, stop breathing, perform artificial respiration, and seek medical attention quickly. In case of leakage, isolate the scene and restrict personnel from entering. Emergency personnel wear protective equipment, collect and clean up the leakage with suitable materials, and do not discard it at will.
Operating 3 - Bromo - 4,5 - Difluoronitrobenzene, must abide by safety and operating standards to prevent accidents and ensure safety. Everyone should keep it in mind, practice and build a safe environment together.
Application Area
Today there is a thing called 3 - Bromo - 4, 5 - Difluoronitrobenzene. This thing has its uses in various fields.
In the field of medicine, it can be used as a key raw material. Because of its unique structure, it can combine with many compounds to produce special drugs to treat diseases, or as antibacterial agents, or as anti-disease drugs, to save people from pain.
In the field of materials, it also has extraordinary power. It can help develop new materials, or increase their stability, or change their optical properties. This material can be used for electronic devices to make their performance better; or for display screens to make images clearer.
In the pesticide industry, it can also play a role. It can produce high-efficiency pesticides, remove pests in the field, protect the growth of crops, help farmers get rich harvests, and help people's livelihood. This is what 3 - Bromo - 4,5 - Difluoronitrobenzene does, and it has its value in all fields.
Research & Development
After tasting the chemical industry, new products have emerged one after another. Among various compounds, 3 - Bromo - 4,5 - Difluoronitrobenzene this thing, which attracted my attention. I have devoted myself to its research.
At the beginning, I explored the method of its synthesis. After repeated tests, I adjusted various conditions, such as temperature and reagent ratio, to obtain a good method. Also study its properties, observe its reaction in different environments, and clarify its characteristics.
Recently, this compound has gradually shown potential in materials, medicine and other fields. I also want to expand its application, hoping to contribute to the development of the industry. Over time, if there is a breakthrough, it will surely be able to promote the progress of related industries and be used by the world. This is my ambition.
Toxicity Research
Yu Taste is dedicated to the research of poisons, and recently focused on 3-Bromo-4,5-Difluoronitrobenzene. This substance is also a chemical product, and the study of its toxicity is quite important.
Looking at its structure, bromine, fluorine and nitro are combined with the benzene ring. Nitro, which has strong oxidizing properties, often leads to changes in the activity of compounds, or involves toxicity. The halogen elements of bromine and fluorine also change their physicochemical properties.
Experiments have shown that it can interact with biomolecules in a specific environment. In cell experiments, it can cause differences in cell morphology, and metabolism is also disturbed by it. In rat experiments, inhalation or percutaneous contact have adverse reactions, and organ function may be damaged.
However, the study of toxicity still needs extensive investigation and in-depth exploration. The influence of environmental factors and the effect of long-term exposure need to be investigated in detail. Hope that follow-up research can clarify its toxicity mechanism, which is a guide for protection and application, to ensure that people are born in a safe place, and to avoid the harm of toxins.
Future Prospects
I have dedicated myself to the study of 3 - Bromo - 4,5 - Difluoronitrobenzene this chemical product. In the current research, it has shown several characteristics and potential. Although there are still limitations in its understanding today, I look to the future, this product will definitely bloom in the chemical field.
It is expected that in the future, through unremitting research and exploration, more subtle chemical properties may be clarified and breakthroughs will be made in the reaction mechanism. In terms of synthesis paths, it is expected to find more efficient and environmentally friendly methods, reduce costs and increase efficiency, and improve output quality.
In the application level, it may emerge in the research and development of new materials, bringing innovation to the electronics, medicine and other industries. Through in-depth investigation, it may become a key factor in promoting the progress of the industry, laying the foundation for future technological development, opening a new chapter, and leading our generation towards a brighter future.
Where to Buy 3-Bromo-4,5-Difluoronitrobenzene in China?
As a trusted 3-Bromo-4,5-Difluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo-4,5-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

3-Bromo-4, what is the main use of 5-Difluoronitrobenzene?
3-Bromo-4,5-difluoronitrobenzene is an important intermediate in organic synthesis. It has a wide range of uses and is often the key raw material for the creation of new drugs in the field of medicinal chemistry. The unique properties of functional groups such as fluorine, bromine and nitro can endow drugs with specific biological activities and pharmacokinetic properties, which can help to synthesize highly selective, potent and low-toxic drug molecules.
In the field of pesticide chemistry, this compound also plays an important role. After rational design and synthesis, high-efficiency, low-residue and environmentally friendly pesticide products can be prepared. Due to its special chemical structure, it can produce significant inhibition or killing effect on specific pests and bacteria, providing a powerful means for pest control in agricultural production.
Furthermore, in the field of materials science, 3-bromo-4,5-difluoronitrobenzene is also used. It can be introduced into the structure of polymer materials through a series of reactions, changing the electrical, optical or thermal properties of the materials, so as to prepare functional materials suitable for special fields, such as photoelectric materials, high-performance engineering plastics, etc.
In summary, 3-bromo-4,5-difluoronitrobenzene, with its unique chemical structure, plays an indispensable and important role in many fields such as medicine, pesticides and materials science, and contributes greatly to the development of related industries.
3-Bromo-4, what are the synthesis methods of 5-Difluoronitrobenzene
The synthesis method of 3-bromo-4,5-difluoronitrobenzene has been known in ancient times and has been studied and improved by many wise men. Today is your description.
First, it can be initiated by halogenation reaction. Using suitable nitrobenzene derivatives as substrates, under specific reaction conditions, bromine atoms and fluorine atoms are introduced. Select suitable halogenating reagents, such as brominating agents and fluorinating agents, and carefully adjust the reaction temperature, time and solvent environment. For example, a nitrobenzene compound is placed in a specific organic solvent, slowly dropwise brominating reagents are added at low temperature, and after several hours of stirring, bromine atoms are precisely placed at the target position, and then fluorine atoms are introduced by specific fluorination methods, and then this compound is obtained.
Second, it can also be synthesized by nucleophilic substitution reaction. First prepare benzene derivatives containing suitable leaving groups, and then use bromine ions and fluorine ions as nucleophiles to implement nucleophilic substitution. The leaving groups need to be carefully selected to make them easy to leave without affecting the stability of other groups on the benzene ring. Control the reaction conditions, such as temperature, pH, etc., so that the nucleophilic substitution can be carried out efficiently, and finally the synthesis of 3-bromo-4,5-difluoronitrobenzene can be achieved.
Third, the use of metal catalysis is also a good method. The reaction of the substrate with halogenated reagents is catalyzed by complexes of metal catalysts such as palladium and copper. Metal catalysts can activate substrates and reagents, reduce the activation energy of the reaction, and promote the introduction of bromine and fluorine atoms. Precisely control the amount of catalyst, ligand structure and reaction atmosphere, so that the reaction can proceed efficiently in the direction of generating the target product, and achieve the synthesis of 3-bromo-4,5-difluoronitrobenzene.
All these synthesis methods have their own advantages and disadvantages. It is necessary to carefully choose according to actual needs and conditions to prepare this compound efficiently.
3-Bromo-4, what are the physical properties of 5-Difluoronitrobenzene
3-Bromo-4,5-difluoronitrobenzene is an important compound in organic chemistry. Its physical properties are well-researched.
When it comes to appearance, it usually takes the form of a white-like to light yellow crystalline powder. The shape of this color state is its primary visual characteristic. It has a certain melting point, which is about a specific temperature range. The value of this melting point varies slightly due to factors such as material purity, but the approximate range can be identified by experimenters.
Furthermore, its solubility is also a key physical property. In common organic solvents, such as ethanol, acetone, etc., it has a certain solubility, but its solubility in water is very small. This difference in solubility is due to the molecular structure characteristics of the compound. It contains functional groups such as bromine, fluorine, and nitro, which makes its molecular polarity different from that of water, so it dissolves differently in water and organic solvents.
In addition, the density of the compound also has its own characteristics. Under normal temperature and pressure, it has a specific density value. This value is related to its actual operation and application, the proportion and state of mixing with other substances, etc.
Its volatility is low, and it is difficult to evaporate into the air under normal temperature. This characteristic affects its stability and safety during storage and use.
In summary, the physical properties of 3-bromo-4,5-difluoronitrobenzene are an indispensable consideration in many fields such as organic synthesis and chemical analysis, which helps researchers better grasp its characteristics and applications.
What is the market price of 3-Bromo-4, 5-Difluoronitrobenzene?
The market price of 3-bromo-4,5-difluoronitrobenzene is difficult to determine. The price of 3-bromo-4,5-difluoronitrobenzene often varies due to various factors, such as the amount of raw materials, the difficulty of preparation, the urgency of demand, and the rise and fall of the market.
If looking at the changes in the market of chemical products in the past, the price of raw materials that are abundant and easy to prepare often stabilizes and may decline; while raw materials are scarce and complex products are prepared, the price is high and fluctuates frequently. For 3-bromo-4,5-difluoronitrobenzene, if the supply of raw materials is sufficient and the preparation process is mature, the price may be within a reasonable range.
However, the market of chemical industry is unpredictable, and sudden increases in demand or sudden decreases in supply can lead to huge changes in prices. In the past, the prices of other chemicals changed in a short time due to sudden conditions. Therefore, in order to know the exact market price of 3-bromo-4,5-difluoronitrobenzene, it is necessary to gain real-time insight into the dynamics of the chemical raw material market, the quotations of manufacturers, and the pattern of supply and demand in the industry. Even with common sense, it is difficult to give accurate figures. Only by looking at market conditions can we obtain its approximate price.
3-Bromo-4, 5-Difluoronitrobenzene What are the precautions during storage and transportation?
3-Bromo-4,5-difluoronitrobenzene is an important chemical in organic synthesis. During storage and transportation, many key matters need to be paid attention to to to ensure its safety and quality.
First talk about storage. This substance should be stored in a cool, dry and well-ventilated place. Cover because of its certain chemical activity, high temperature and humid environment can easily cause chemical reactions and damage its quality. And it needs to be kept away from fires and heat sources, because it is exposed to open flames, hot topics or the risk of combustion and explosion. The storage place should be equipped with suitable materials to contain leaks to prevent accidental leaks from being handled in time to avoid the spread of pollution. In addition, it should be separated from oxidants, edible chemicals, etc., and must not be mixed. If different chemicals come into contact with each other, they may cause violent reactions and cause danger.
As for transportation. Before transportation, make sure that the packaging is complete and the loading is safe. The packaging must comply with relevant regulations, which can effectively prevent the leakage and volatilization of substances. During transportation, the speed of the vehicle should not be too fast, and it should not be braked abruptly to avoid damage to the packaging due to collision and vibration. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During transportation, it is necessary to prevent exposure to the sun, rain, and high temperature. If transported by water, it should be prevented from flowing into the water body, because it is toxic to aquatic organisms or will damage the aquatic ecological environment. Transport personnel also need to undergo professional training to be familiar with the characteristics of the chemical and emergency treatment methods to ensure the safety of the entire transportation process.