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3-Bromo-2-Cyanofluorobenzene

3-Bromo-2-Cyanofluorobenzene

Hongda Chemical

Specifications

HS Code

201838

Chemical Formula C7H3BrFNO
Molecular Weight 216.007 g/mol
Appearance Typically a colorless to light - colored liquid or solid
Boiling Point Data may vary, but generally in the range where aromatic halides and nitriles boil
Density Characteristic value based on its mass - volume relationship
Solubility In Water Low solubility due to its non - polar aromatic and halogenated structure
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Flash Point Value indicating the temperature at which it can form a flammable vapor - air mixture
Vapor Pressure Measure of the pressure exerted by its vapor at a given temperature

As an accredited 3-Bromo-2-Cyanofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - bromo - 2 - cyanofluorobenzene packaged in a sealed glass bottle.
Storage 3 - bromo - 2 - cyanofluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases as it may react with them. Label the storage container clearly to avoid misidentification.
Shipping 3 - bromo - 2 - cyanofluorobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packaged to prevent leakage. Shipments follow strict hazardous chemical regulations, ensuring safe transport.
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3-Bromo-2-Cyanofluorobenzene 3-Bromo-2-Cyanofluorobenzene
General Information
Historical Development
3-Bromo-2-cyanofluorobenzene is also a product of chemistry. Its initial exploration began with a number of thirsty chemists. At that time, the conditions were difficult and the equipment was simple, but it was determined and worked tirelessly.
At the beginning, its properties could only be speculated in the signs of the end. After repeated tests and analyzing the reaction, I began to know a thing or two about it. Years pass, and the successors follow the ambitions of their predecessors and strive for excellence.
With the advance of science and technology, the research method has gradually improved, and the understanding of 3-bromo-2-cyanofluorobenzene has deepened. From the initial observation of its properties to the analysis of its structure, it all depends on the efforts of scholars day and night. The historical evolution of this product is actually a microcosm of the chemical research path, witnessing the dedication and wisdom of countless researchers, and paving the foundation for future chemical exploration.
Product Overview
3 - Bromo - 2 - Cyanofluorobenzene Product Overview
Today there is a product called 3 - Bromo - 2 - Cyanofluorobenzene. It is an important intermediate in organic synthesis and has key uses in many fields such as medicine and pesticides.
Looking at its structure, above the benzene ring, bromine (Bromo), cyano (Cyan) and fluoro (fluoro) are cleverly connected, giving this compound a unique chemical activity. The presence of bromine atoms makes the molecule prone to nucleophilic substitution reactions, creating an opportunity for the introduction of other functional groups. Cyanyl not only enhances the stability of the molecule, but also further converts into a variety of useful functional groups, expanding its application in synthetic routes. The properties of fluorine atoms change the electron cloud distribution of molecules and affect the physical and chemical properties of compounds, such as lipophilicity, which is of great significance in drug development.
Due to its special structure and activity, 3-Bromo-2-Cyanofluorobenzene plays an indispensable role in the stage of organic synthesis, providing a solid material foundation for the creation of novel and efficient pharmaceutical and pesticide products.
Physical & Chemical Properties
3 - Bromo - 2 - Cyanofluorobenzene is a unique compound. Its physical and chemical properties are of great research value. Looking at its physical properties, at room temperature, this substance may assume a specific state or have a unique color. The number of its melting and boiling points is related to its state changes in different environments.
Regarding its chemical properties, the presence of bromine, cyanyl and fluorine atoms in the molecule endows it with active reactivity. Bromine atoms can undergo substitution reactions under specific conditions, while cyanyl groups can participate in various addition reactions. Fluorine atoms also have a significant impact on the electron cloud distribution and reaction selectivity of molecules. In the field of organic synthesis, this compound can be used as a key intermediate to participate in the construction of various complex organic molecules, opening up new avenues for chemical research and industrial production. It is indeed worthy of in-depth investigation in the field of chemistry.
Technical Specifications & Labeling
Nowadays, there is a chemical substance 3 - Bromo - 2 - Cyanofluorobenzene. In the field of chemical industry, its technical specifications and identification (product parameters) are crucial. The technical specifications of this substance are related to the preparation process, purity standards, etc. The preparation needs to follow a precise process, temperature control, time control, and selection of appropriate raw materials and catalysts to ensure purity standards.
In terms of identification, product parameters should be detailed. If the proportion of ingredients needs to be confirmed, the amount of bromine, cyanyl and fluorine should be accurately marked. The appearance and properties should not be ignored. The description of its color and state helps the user to clarify its characteristics. In addition, the safety label is also heavy, indicating its dangerous properties to prevent harm before it occurs. In this way, strict adherence to technical specifications and clear labeling can ensure that this product can be used in chemical applications for a long time.
Preparation Method
The method of making 3 - Bromo - 2 - Cyanofluorobenzene is selected as the first raw material. When fluorobenzene is used as the starting material, its properties are stable and easy to buy. First, the fluorobenzene and bromine are reacted under appropriate catalysts and conditions. In this step, the temperature needs to be controlled moderately, and brominated to obtain o-bromofluorobenzene.
Then the o-bromofluorobenzene reacts with the cyanide reagent and cyanides. In this reaction step, the proportion of reagents needs to be carefully adjusted and the reaction environment should be paid attention to. The mechanism of the reaction is based on the nucleophilic substitution of halogenated aromatics. After these two steps, 3 - Bromo - 2 - Cyanofluorobenzene During the preparation process, the products of each step need to be properly separated and purified to ensure the purity of the final product. Although this method is not the only one, the raw materials and process are more suitable and better results can be obtained.
Chemical Reactions & Modifications
3 - Bromo - 2 - Cyanofluorobenzene is an important compound in organic synthesis. The study of its chemical reaction and modification is of great significance in the field of chemistry.
Looking at its chemical reaction, it often involves nucleophilic substitution. Due to the characteristics of bromine, cyanyl and fluorine, it can attract nucleophilic reagents to attack. If a nucleophilic reagent reacts with it, it can realize the substitution of bromine atoms and generate new derivatives according to the reaction conditions. In this process, the control of reaction conditions is extremely critical. Temperature, solvent, catalyst, etc., all affect the reaction rate and product selectivity.
Discusses modification to optimize its properties. Its physical and chemical properties can be changed by introducing specific functional groups. For example, the introduction of nitrogen-containing heterocycles through specific reactions may enhance their solubility in specific solvents or enhance their biological activity. Such modification may open up new applications in pharmaceutical chemistry, materials science and other fields.
Synonyms & Product Names
The name of the chemical object, "3 - Bromo - 2 - Cyanofluorobenzene", is the name of its synonym and trade name, which is related to the importance of chemical research. This substance may have another name to meet the needs of different users, and the name of the trade name is also to identify its quality and source.
In the field of chemistry, there are many people who have the same thing but different names, all of which are convenient for research. "3 - Bromo - 2 - Cyanofluorobenzene", or because of its structure and nature, so that researchers can adapt to each other in communication and writing. As for the name of the trade name, it is the manufacturer who recognizes the characteristics of its products and is different from his family.
Chemical researchers of our generation must carefully investigate their similar names and trade names, so as to understand the use of this substance in chemical and pharmaceutical fields, and seek for the advancement of academic research and the prosperity of the industry. Only by understanding its name and examining its quality can we reach the depth of chemical inquiry.
Safety & Operational Standards
3 - Bromo - 2 - Cyanofluorobenzene is an important raw material in chemical synthesis. It is related to experimental safety and operation standards and should not be underestimated.
In the category of safety, this compound has certain latent risks. Its characteristics of bromine, cyanyl and fluorine atoms may bring different degrees of harm. Bromine is active, or irritates the human respiratory tract and skin. If you inadvertently inhale volatile gases containing bromine, it can cause symptoms such as cough and asthma, and in severe cases, it may damage the respiratory mucosa. Skin contact may cause allergic reactions such as redness, swelling, and pain. Cyanyl toxicity is particularly strong. Although the stability of this compound is relatively high, under certain conditions such as high temperature, strong acid and alkali environment, or the release of highly toxic hydrogen cyanide gas, once inhaled, it can be life-threatening in a short time. Fluorine atoms are also corrosive and have an erosive effect on human tissue. After exposure, chemical burns may be caused.
In terms of operating specifications, adequate preparation is required before the experiment. Experimenters should be familiar with the properties, latent risks and emergency treatment methods of 3-Bromo-2-Cyanofluorobenzene. When entering the laboratory, be sure to wear complete protective equipment, including laboratory clothes, protective gloves, goggles and gas masks. The experimental site should be well ventilated and equipped with high-efficiency ventilation equipment to discharge volatile harmful gases in time.
When taking this compound, use a precise measuring tool, and measure it accurately according to the experimental requirements to avoid waste and pollution. The operation process strives to be cautious to prevent it from spilling or splashing out. If it is accidentally spilled, emergency treatment procedures should be started immediately. If a small amount is spilled, quickly cover the adsorption with inert materials such as sand and vermiculite, collect it in a specific container, and dispose of it according to regulations. If a large number of spills need to be evacuated, the scene should be blocked, and the professional personnel will handle it.
After the experiment is completed, the waste containing 3-Bromo-2-Cyanofluorobenzene should not be discarded at will. It should be collected by category, labeled clearly, indicating the composition, quantity and hazard characteristics, and handed over to a professional organization for proper disposal in accordance with environmental protection regulations. This way, we can ensure the safety of the experiment and protect the environment from pollution.
Application Area
3-Bromo-2-cyanofluorobenzene is a new chemical product. Its application field is quite wide. In the field of medicinal chemistry, this product can be a key intermediary. With its unique molecular structure, it can cooperate with many bioactive molecules to help medical scientists synthesize special drugs and cure various diseases.
In the field of material science, it is also used for extraordinary purposes. It can be integrated into new materials through special processes to give the material specific properties, such as enhancing its stability and changing its optical properties.
In addition, in the field of organic synthesis, it is often an important starting material. Chemists use their unique functional groups to perform delicate reactions, build complex and diverse organic molecular structures, expand the boundaries of organic synthesis, and contribute to the development of chemical research.
Research & Development
In recent years, Yu has dedicated himself to the research of 3-Bromo-2-Cyanofluorobenzene. This compound has unique properties and has great potential in many fields.
At the beginning, it was very difficult to explore its synthesis path. The traditional method has low yield or many impurities. Yu studied the classics painstakingly, referred to the experience of previous sages, and after repeated experiments, he finally obtained an improved method, with gradually increasing yield and high purity.
After obtaining a pure product, he studied its characteristics. After spectral analysis, thermogravimetric testing, etc., its structure and stability were clarified. In terms of reactivity, there are also unique discoveries, which lay the foundation for subsequent applications.
Looking to the future, its application prospects are broad. In the field of medicine, it may be used as a key intermediate to help the research and development of new drugs; in materials science, it is also expected to give birth to new functional materials. Yu should make unremitting efforts to expand its application, contribute to the academic community and industry, and promote the research and development of this compound to a new level.
Toxicity Research
The name 3-Bromo-2-Cyanofluorobenzene is known to me, and its toxicity is related to toxicology, which is quite important. We study the toxicity of this substance to understand its impact on living things.
Looking at the structure of its molecules, bromine and cyanyl coexist with fluorine atoms. The characteristics of these atoms may cause the substance to have different toxicity. It is reasonable to infer that cyanide is highly toxic, and fluorine atoms have different activities. The two may lead to a series of biochemical changes in the organism.
However, in order to determine its toxicity, it is still necessary to test it. Take various organisms as samples to observe their symptoms after being affected by the substance, such as changes in physiological functions, cell states, etc. Recorded in detail, analysis of the data, we can know the true appearance of 3 - Bromo - 2 - Cyanofluorobenzene toxicity, for later generations to use this material, showing a preventive policy, to avoid its harm and seek its benefits, this is our generation of research toxicity of the squid.
Future Prospects
Today, there is a chemical product called 3-Bromo-2-Cyanofluorobenzene, which I have dedicated myself to researching. Its future prospects are quite impressive.
This substance has unique properties and has potential uses in many fields. In the future, it may emerge in the field of materials science and contribute to the research and development of new materials. Its special structure may endow materials with different properties, such as stronger stability and unique optical properties.
Furthermore, it is also expected to play a role in biomedicine. After delicate design and modification, it may become a key component of targeted drugs, accurately acting on lesions and helping medical progress.
I firmly believe that over time, with the unremitting research of scientific researchers, 3 - Bromo - 2 - Cyanofluorobenzene will be able to shine, open up a new world for future development, and lead related fields to a higher level.
Where to Buy 3-Bromo-2-Cyanofluorobenzene in China?
As a trusted 3-Bromo-2-Cyanofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo-2-Cyanofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 3-Bromo-2-Cyanofluorobenzene?
3-Bromo-2-cyanofluorobenzene is also an organic compound. It has halogen atoms (bromine and fluorine) and cyanobenzene groups, which give it unique chemical properties.
In terms of reactivity, bromine atoms are excellent leaving groups for nucleophilic substitution reactions. Because the electronegativity of bromine atoms is higher than that of carbon, the carbon-bromine bond electron cloud is biased towards bromine, causing carbon to be partially positively charged and vulnerable to attack by nucleophilic reagents, triggering nucleophilic substitution reactions. If nucleophilic reagents such as alkoxides and amines interact with 3-bromo-2-cyanofluorobenzene, bromine atoms can be replaced to form new compounds.
Cyanyl groups are also highly reactive. Cyanyl groups can be hydrolyzed to form carboxyl groups. Under acidic or basic conditions, cyanyl groups are gradually converted to amides first and finally carboxylic acids. This reaction is an important method for introducing carboxyl groups in organic synthesis. And cyanyl groups can be converted into amine groups through reduction reactions. Commonly used reducing agents such as lithium aluminum hydride can reduce cyanyl groups to obtain corresponding amine compounds, which are crucial in the synthesis of nitrogenous compounds.
Although fluorine atoms are extremely electronegative and have high carbon-fluorine bond energy, it is relatively difficult to undergo substitution reactions. However, under specific conditions, such as the use of strong nucleophiles and appropriate catalysts, fluorine atom substitution may also occur. The presence of fluorine atoms can affect the electron cloud distribution and spatial structure of molecules, and then affect the physical and chemical properties of compounds, such as molecular polarity, fat solubility, etc. In the field of pharmaceutical chemistry, fluorine atoms are often used to optimize the properties of drug molecules.
The properties of functional groups contained in 3-bromo-2-cyanofluorobenzene are widely used in the field of organic synthesis, and can be used to construct a variety of complex organic compound structures through different reaction paths.
What are the main uses of 3-Bromo-2-Cyanofluorobenzene?
3-Bromo-2-cyanofluorobenzene is also an organic compound. It has a wide range of uses in the field of medicinal chemistry and is a key intermediate for the synthesis of many drugs. Due to the unique activities of bromine, cyano and fluorine atoms in molecules, complex drug molecular structures can be precisely constructed through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., so it plays an important role in the development of innovative drugs.
In the field of materials science, it also has extraordinary performance. Polymer systems can be introduced through specific reactions, and the electrical, optical and thermal properties of materials can be improved by their special electronic effects and spatial structures. For example, the preparation of organic semiconductor materials with special photoelectric properties can be used in organic Light Emitting Diode (OLED), organic solar cells and other devices to improve their performance and efficiency.
In pesticide chemistry, 3-bromo-2-cyanofluorobenzene is also indispensable. It can be used as a raw material for the synthesis of high-efficiency and low-toxicity pesticides. By modifying its structure, the pesticide is endowed with unique biological activity and selectivity, which can play an effective role in the control of specific pests or pathogens, and can reduce the adverse effects on the environment and non-target organisms, meeting the needs of modern green pesticide development. In conclusion, 3-bromo-2-cyanofluorobenzene, with its unique chemical structure, has shown important application value in many fields such as medicine, materials, and pesticides, and is an important material basis for promoting technological progress and innovation in related fields.
What are 3-Bromo-2-Cyanofluorobenzene synthesis methods?
The synthesis methods of 3-bromo-2-cyanobenzene fluoride have different paths, which are described in detail below.
First, o-fluorobenzoic acid is used as the starting material. First, the reaction of o-fluorobenzoic acid with dichlorosulfoxide can obtain o-fluorobenzoyl chloride. This step takes advantage of the higher activity of acid chloride than carboxylic acid. The reaction conditions are mostly heating and refluxing, so that the two can fully react and obtain o-fluorobenzoyl chloride in a high yield. Then, the o-fluorobenzoyl chloride reacts with sodium cyanide in a suitable solvent and is replaced by nucleophilic to obtain o-fluorobenzonitrile. This process requires attention to the highly toxic properties of cyanide, and the operation must be cautious. Finally, bromine atoms are introduced into a specific position of the benzene ring of o-fluorobenzonitrile. A brominating agent such as N-bromosuccinimide (NBS) can be used, and benzoyl peroxide is used as an initiator to react under light or heating conditions to obtain 3-bromo-2-cyanobenzene.
Second, o-fluorobenzene is used as the starting material. First, it is reacted with magnesium chips to make Grignard's reagent. This process needs to be carried out in an anhydrous and oxygen-free environment to ensure the stability of Grignard's reagent. Subsequently, Grignard's reagent reacts with cyanyl reagents such as cuprous cyanide, and cyanyl groups can be introduced into the benzene ring to obtain o-fluorobenzonit Finally, the target product 3-bromo-2-cyanofluorobenzene can also be obtained through bromination reaction.
Third, 2,3-difluorobenzonitrile is used as raw material. Using the nucleophilic substitution reaction of bromine atom to fluorine atom on benzene ring, select suitable base and reaction conditions, such as potassium carbonate and other bases, in polar solvents, react with brominating reagents to promote bromine atom to selectively replace fluorine atom at a specific position, and then successfully synthesize 3-bromo-2-cyanofluorobenzene.
All kinds of synthesis methods have their own advantages and disadvantages. In practical applications, careful choices should be made based on the availability of raw materials, cost, difficulty of reaction conditions, and product purity.
3-Bromo-2-Cyanofluorobenzene What are the precautions in storage and transportation?
3-Bromo-2-cyanofluorobenzene is also a chemical substance. When storing and transporting, there are several ends that should be paid attention to.
First words storage, this substance should be placed in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, high temperature and humid environment, it is easy to cause it to deteriorate. If it is exposed to high temperature, it may cause changes in its internal structure, which will affect its chemical properties; in case of moisture, or biochemical reactions, its purity will be damaged. Therefore, it is crucial to choose a suitable storage environment.
And it must be kept away from fire and heat sources. 3-Bromo-2-cyanofluorobenzene may be flammable. In case of open flames and hot topics, it may lead to fire and endanger storage safety. Furthermore, it should be stored separately from oxidants, acids, alkalis, etc. These substances are prone to chemical reactions in contact with them, or cause serious accidents such as explosions and leaks.
As for transportation, be sure to ensure that the packaging is complete and sealed. If the packaging is damaged, the substance or leakage will not only damage the transportation vehicle, but also pose a threat to the surrounding environment and personal safety. During transportation, it should also be protected from exposure to the sun, rain, and high temperature. When driving, drivers must be cautious to prevent bumps and collisions and damage to the packaging.
The means of transportation must also be clean, and no other chemical substances should be left to avoid reaction with 3-bromo-2-cyanofluorobenzene. And the transportation personnel should be familiar with the characteristics and emergency treatment methods of this substance. In case of an accident, they can respond quickly and reduce the harm.
In summary, when storing and transporting 3-bromo-2-cyanofluorobenzene, the environment, packaging, isolation and personnel cognition should not be ignored, so as to ensure its safety and avoid accidents.
What is the market price of 3-Bromo-2-Cyanofluorobenzene?
3-Bromo-2-cyanofluorobenzene is an important chemical raw material in the field of organic synthesis. Its market price often fluctuates due to many factors, and it is difficult to give an exact value.
The first to bear the brunt, the cost of raw materials is a key factor. For the preparation of this compound, the price fluctuation of raw materials is directly related to its production cost. If the supply of basic raw materials required for preparation is tight or the price rises, the price of 3-bromo-2-cyanofluorobenzene will also rise.
Furthermore, the complexity of the preparation process also affects the price. If the synthesis of this compound requires delicate and complex steps, involving multi-step reactions, special reaction conditions or expensive catalysts, the production cost will increase significantly, which will in turn push up the market price.
The relationship between supply and demand in the market is also an important consideration. If there is a period of strong demand for 3-bromo-2-cyanobenzene in many industries, but the supply is relatively insufficient, the price will naturally rise; conversely, if the market demand is weak and the supply is excessive, the price may trend down.
In addition, the scale of production also has an impact. In large-scale production, due to the scale effect, the unit production cost may be reduced and the price may be more competitive; in small-scale production, the cost is relatively high and the price will be higher.
In summary, the market price of 3-bromo-2-cyanofluorobenzene is influenced by many factors such as raw material cost, preparation process, supply and demand relationship, and production scale, and its price may fluctuate within a wide range, so it is difficult to determine its specific market price.