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3-Bromo-2,4-Difluoronitrobenzene

3-Bromo-2,4-Difluoronitrobenzene

Hongda Chemical

Specifications

HS Code

698820

Chemical Formula C6H2BrF2NO2
Molecular Weight 254.98
Physical State At Room Temperature Solid
Solubility In Water Low solubility in water (organic halonitrobenzene compounds are generally hydrophobic due to the non - polar aromatic ring and nitro and halogen groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate (due to its non - polar nature)

As an accredited 3-Bromo-2,4-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - bromo - 2,4 - difluoronitrobenzene packaged in a sealed glass bottle.
Storage 3 - bromo - 2,4 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizers and reducing agents. Store in a tightly - sealed container to prevent leakage and vapor release, which could pose risks due to its potentially harmful nature.
Shipping 3 - bromo - 2,4 - difluoronitrobenzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. It must be properly packaged to prevent leakage, and transported by carriers licensed for such chemicals.
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3-Bromo-2,4-Difluoronitrobenzene 3-Bromo-2,4-Difluoronitrobenzene
General Information
Historical Development
In the past, the art of chemistry has gradually flourished, and many novel substances have been created. 3 - Bromo - 2, 4 - Difluoronitrobenzene such substances have also emerged in the process of chemical evolution.
In the early days, chemists explored the synthesis method in the subtle laboratory with exquisite skills and unremitting research. After countless attempts, they explored the laws among the complex chemical reactions. At that time, the instruments were still simple, thanks to the keen insight and exquisite operation of chemists.
With the passage of time, technology has advanced day by day, and the synthesis method has been constantly innovated. The introduction of new equipment has made the reaction conditions more precise and controllable, and the yield and purity have been greatly improved. From the initial difficult preparation of a small amount to today's large-scale production, this substance has been widely used in the field of chemistry, laying the foundation for many research and industrial development, and leaving a deep imprint on the long history of chemistry.
Product Overview
There is a substance named 3 - Bromo - 2,4 - Difluoronitrobenzene. Its shape is an organic compound. Looking at its structure, above the benzene ring, bromine atoms, fluorine atoms and nitro groups are in their respective positions. Bromine is in the third position; the second and fourth positions are occupied by fluorine atoms, and nitro groups are also attached to the ring.
The properties of this substance have unique chemical activities due to the presence of halogen atoms and nitro groups. The halogen atom allows it to participate in the reaction of nucleophilic substitution, and the nitro group changes the electron cloud density of the benzene ring, affecting the reaction activity and direction. In the field of organic synthesis, it is a key intermediary. It can be prepared through various paths and used to create other types of organic compounds. It is useful in the fields of medicine, pesticides, and materials. It can contribute to the development of new products and the advancement of the industry.
Physical & Chemical Properties
3 - Bromo - 2,4 - Difluoronitrobenzene is an important compound in organic synthesis with unique physical and chemical properties. Looking at its physical properties, it is mostly a solid state at room temperature, with a specific melting point and boiling point. The exact value of the melting point varies according to the purity, but it is roughly within a certain temperature range. This property is helpful for the purification and identification of compounds. The boiling point is also a key physical constant, reflecting the energy required for its gasification.
Discussing the chemical properties, the presence of bromine, fluorine and nitro in this compound makes it active chemically. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and changes the activity of electrophilic substitution. Bromine and fluorine atoms can participate in nucleophilic substitution reactions, and halogen atoms can be replaced by nucleophilic reagents to construct new carbon-heteroatom bonds, which is of great significance in the field of organic synthesis. Such unique physical and chemical properties establish its irreplaceable position in many chemical synthesis reactions.
Technical Specifications & Labeling
3 - Bromo - 2,4 - Difluoronitrobenzene is an important chemical substance. Its preparation process is very critical. In the reactor, the reaction is carried out under suitable temperature and pressure conditions with specific raw materials and accurate proportions. The reaction time needs to be strictly controlled to ensure the complete reaction.
The detection of its quality cannot be ignored. The appearance needs to be a specific color state. After instrument analysis, the purity should reach the specified standard, and the impurities should not exceed the limit. Its physical and chemical parameters, such as melting point, boiling point, etc., should conform to the established indicators. Only by meeting these technical specifications and standards (product parameters) can it be described as a high-quality 3-Bromo-2, 4-Difluoronitrobenzene product, which can be effectively applied in related fields.
Preparation Method
To make 3 - Bromo - 2,4 - Difluoronitrobenzene this material, the required raw materials and production method are as follows:
raw materials, when preparing fluorobenzene, bromine, nitric acid, sulfuric acid, etc. At the beginning of the production method, fluorobenzene is first placed in the reaction kettle, mixed with sulfuric acid and nitric acid, slowly added to control its temperature and rate, this is the step of nitrification, to obtain 2,4 - difluoronitrobenzene.
Next, 2,4 - difluoronitrobenzene and bromine are added to the reaction kettle with the help of a specific catalyst, and then the temperature and pressure are adjusted. The reaction of bromination is carried out, and 3 - Bromo - 2,4 - Difluoronitrobenzene is obtained. When preparing
, each step requires careful attention to factors such as temperature, pressure, and reactant ratio, and a safety prevention and control mechanism is set up to ensure that the preparation is smooth and the product is pure.
Chemical Reactions & Modifications
3 - Bromo - 2,4 - Difluoronitrobenzene is an important chemical compound. In the field of chemistry, it is crucial to investigate its chemical reactions and modifications.
Its chemical reactions often involve substitution reactions, etc. Through subtle selection of reaction reagents and conditions, specific modifications can be made to its structure. For example, changing the reaction temperature, pH and ratio of reactants will have a significant impact on the reaction process and product characteristics.
Modifications are designed to improve its chemical properties. Or enhance its stability, or optimize its reactivity to be suitable for multiple scenarios. This process requires fine control, considering the relationship between structure and performance at the molecular level, applying chemical principles to achieve the best modification effect, laying the foundation for the wide application of the compound in various fields, and promoting the development of chemical research and practical applications.
Synonyms & Product Names
Today there is a thing called 3 - Bromo - 2,4 - Difluoronitrobenzene. This thing is very important in the field of my chemical research. Its synonymous names can also be investigated.
Find its synonyms, or names according to its properties and structures. It has bromine (Bromo), fluorine (Fluoro) and nitro (nitro). According to this chemical property, it may be called "bromofluoronitrobenzene".
As for the trade name, it may be named by researchers and manufacturers according to its use and characteristics. Or because of its high efficiency in a certain type of reaction, it is called "rapid response bromofluoronitrobenzene"; or because of its excellent purity, it is called "high purity bromofluoronitrobenzene".
In the exploration of chemistry, clarify its synonyms and trade names, help us to distinguish its quality and use its energy, so as to promote the progress of chemical research and contribute to the development of science and technology.
Safety & Operational Standards
3 - Bromo - 2,4 - Difluoronitrobenzene Safety and Operating Specifications
Husband 3 - Bromo - 2,4 - Difluoronitrobenzene, an important thing in chemical research. During its experimental operation, safety comes first, and norms are important.
Looking at its physical properties, this substance may have a special color, taste and state, but it is much irritating. Therefore, when handling, it must be done in a well-ventilated manner. If in a narrow chamber, gas accumulates, it is easy to cause respiratory diseases, and even damage the organs.
As for contact prevention, it is impossible to ignore. Protective equipment such as gloves, goggles, etc. Gloves should be chemically resistant to prevent them from penetrating into the skin of the hands. Goggles can protect the eyes from splashes. If you accidentally touch the skin, rinse it with plenty of water as soon as possible, and then seek medical treatment.
Furthermore, its storage is also subject to regulations. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Because of its risk of explosion, it may change unexpectedly in case of heat or strong oxidants. And the storage place should be clearly marked, so that people can know the danger at a glance.
In terms of experimental operating norms, when weighing, you must use a precise device, according to the needs of the prescription, no more or less. When mixing, also slowly pour in, stir well, must not be too hasty, causing the reaction to get out of control.
In short, 3 - Bromo - 2,4 - Difluoronitrobenzene Although it is useful for scientific research, its safety and operating standards, researchers must not be careful and follow, in order to ensure the smooth experiment, personal safety.
Application Area
In the field of medicine, it can be used as a key raw material for the synthesis of special agents. With its unique chemical structure, it can accurately participate in the reaction, help generate ingredients with special pharmacological activities, and cure various diseases.
In the field of materials, it can be integrated into the preparation of new materials. Give the material unique properties, such as enhancing its stability and changing its optical properties, so that the material is suitable for a variety of high-tech scenarios.
In agriculture, it may contribute to the creation of high-efficiency pesticides. With its chemical properties, it has developed a highly targeted agent for pests and diseases, protecting the growth of crops and ensuring a bumper harvest. This is the application field of 3-Bromo-2,4-Difluoronitrobenzene, which is a treasure in the chemical industry.
Research & Development
Today, there are chemical substances 3 - Bromo - 2,4 - Difluoronitrobenzene. I am a researcher of chemical products, and I am very attentive to its research and development. This substance has unique properties, and its combination of bromine, fluorine and nitro groups gives it special chemical activity.
We have repeatedly experimented to explore its reaction mechanism. Observe its reaction with various reagents, and analyze the structure and properties of the product in detail. We hope to find an optimized synthesis path to improve yield and purity.
During the research process, its stability and safety are also concerned. After many tests, it is known that it is suitable for storage and use conditions. We hope that through our research, 3 - Bromo - 2,4 - Difluoronitrobenzene can be widely used in chemical, pharmaceutical and other fields, promote the development of related industries, and seek well-being for the world.
Toxicity Research
Today, there is a substance, named 3-Bromo-2,4-Difluoronitrobenzene, which is very important for my chemical research and the investigation of its toxicity.
Looking at this substance, its molecular structure is unique, with bromine, fluorine, nitro and other groups coexisting on a benzene ring. This structure may cause it to have special chemical activity, and its activity is often associated with toxicity.
After various experiments, observe its effect on organisms. Taking small animals as samples, when this substance is administered, it is seen that its physiological function is gradually abnormal. Slow movement, reduced eating, and signs of organ damage.
From this, the toxicity of 3 - Bromo - 2,4 - Difluoronitrobenzene should not be underestimated. During industrial production and use, strict protection measures should be set up to prevent this object from harming life and preventing it from defiling the environment. Only in this way can we ensure the safety of people and all things, and the road of chemical research can be feasible for a long time.
Future Prospects
Husband 3 - Bromo - 2,4 - Difluoronitrobenzene, it is also a matter of transformation. In today's world, its use is enough. In the field of work, it is possible to create a kind of material, and its foundation. The research of is also often based on this, hoping that it can become a special effect.
Looking to the future, the way to its development is full of hope. Those who are scientific must study its properties and make good use of its capabilities. Or they can develop new methods, improve its efficiency and reduce its cost. Make this compound more useful to the world, and bring happiness to people. Or use it to explore the unknown, and new technologies, such as material innovation and refined technology, have great benefits. In the unseen scene, it must be transformed, and this compound must also be included in it, developing its majestic appearance and becoming a work of thousands of years.
Where to Buy 3-Bromo-2,4-Difluoronitrobenzene in China?
As a trusted 3-Bromo-2,4-Difluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Bromo-2,4-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 3-bromo-2,4-difluoronitrobenzene?
3-Hydroxy-2,4-diallyl anisole is an organic compound. Its physical properties are quite specific, let me tell you.
Looking at its properties, under normal circumstances, it is mostly colorless to light yellow oily liquid, which is a significant feature of its appearance. Close to the fine smell, it has a unique aromatic smell, its fragrance is fresh and deep, like the fragrance of mountains and forests, mixed with a little subtle smell of herbs, it is refreshing to smell.
As for its volatility, it is relatively moderate. It is neither extremely volatile and fleeting, nor difficult to evaporate and lasting. In a normal temperature environment, it can slowly emit its aroma and gradually diffuse in the air.
In terms of solubility, this compound is insoluble in water, and the interaction with water molecules is weak due to its molecular structure characteristics. However, in organic solvents, such as ethanol, ether, etc., it exhibits good solubility and can be miscible with organic solvents, uniformly dispersed in it.
Its density is slightly smaller than that of water. If it is placed in the same container as water, it can be seen that it floats on the water surface, and the two are clearly defined.
Melting point and boiling point are also important physical properties. Its melting point is low, it is not a solid state at room temperature, and its boiling point is relatively high. It needs to be changed from liquid to gaseous under specific temperature conditions. This boiling point characteristic also determines its stability in general environments.
These physical properties make 3-hydroxyl-2,4-diallyl anisole possible in many fields, or for fragrance preparation to add unique flavor; or for organic synthesis, because of its specific physical and chemical properties, it can provide a basis for the synthesis of new compounds.
What are the main uses of 3-bromo-2,4-difluoronitrobenzene?
3-Hydroxy-2,4-diallyl anisole has a wide range of main uses. In the field of medicine, it can help disease treatment and drug research and development. Because of its unique chemical structure and activity, it can be used as a drug intermediate, chemically modified and modified to make drugs with specific pharmacological activities, which are used to fight inflammation, tumors and other diseases. In the fragrance industry, it emits a unique aroma and can be mixed in a variety of flavors and fragrances, adding charming fragrance to perfumes, air fresheners, detergents, etc., giving products unique odor characteristics and enhancing the olfactory attractiveness of products. In the food industry, it can be used as a food additive to enhance flavor and flavor, such as in baked goods, beverages, candies, etc., to enhance food flavor and enhance consumer taste experience. In agriculture, it has repellent or inhibitory effects on some pests, and is expected to be developed as green and environmentally friendly pesticides, reducing the use of chemical pesticides and contributing to sustainable agricultural development. In the field of chemical synthesis, it is an important raw material, participating in many organic synthesis reactions, used to manufacture high value-added chemical products, providing a key foundation for the development of the chemical industry.
This substance plays a key role in many industries. With the progress of science and technology and the deepening of research, its use may be further expanded and deepened.
What are the synthesis methods of 3-bromo-2,4-difluoronitrobenzene?
To prepare 3-bromo-2,4-diethylphenyl ether, the following ancient methods can be used.
The Williamson synthesis method is the first, which is a classic for ether production. 2,4-diethylphenol and bromoalkane are used as raw materials and reacted in an alkaline environment. First take an appropriate amount of 2,4-diethylphenol and place it in a reactor. Add an appropriate amount of alkali, such as sodium hydroxide or potassium hydroxide. The alkali can deprotonate the phenolic hydroxyl group to form phenoxy anions, which have strong nucleophilic properties. Then, slowly drop into bromoalkane, bromine atom of bromoalkane as a good leaving group, phenoxy negative ions nucleophilic attack carbon atom of bromoalkane, bromine ions leave, and then form 3-bromo-2,4-diethylphenyl ether. This reaction conditions are mild and the yield is quite high.
can also be used Ullmann (Ullmann) reaction. The phenol salt of 2,4-diethylphenol and bromoaromatics are used as raw materials, supplemented by copper or copper salts as catalysts, and react at high temperature. Mix 2,4-diethylphenol with base to make phenol salt. Then an appropriate amount of copper powder or a copper catalyst such as cuprous chloride is added, and it is co-placed in a reaction vessel with bromoaromatics and heated to an appropriate temperature. The copper catalyst can promote the coupling reaction between phenolates and bromoaromatics to form the target product 3-bromo-2,4-diethylphenyl ether. However, this reaction requires a higher temperature and requires slightly higher reaction equipment.
In addition, the phase transfer catalytic synthesis method is also feasible. In the water-organic two-phase system, a phase transfer catalyst such as quaternary ammonium salt or crown ether is added. Using 2,4-diethylphenol, base and bromoalkane as reactants, the phase transfer catalyst can transfer the phenoxy anion in the aqueous phase to the organic phase and fully contact the bromoalkane for reaction. This method is simple to operate, has a fast reaction rate, and avoids the use of expensive catalysts, which has many advantages.
In summary, according to the actual situation, such as the availability of raw materials, reaction equipment, cost and other factors, a suitable method can be selected to prepare 3-bromo-2,4-diethylphenyl ether.
What are the precautions for 3-bromo-2,4-difluoronitrobenzene during storage and transportation?
3-Bromo-2,4-dipentenyl phenyl ether, when storing and transporting, many matters need to be paid attention to.
Its nature or instability, when storing, should be placed in a cool, dry and well ventilated place. Avoid open flames and hot topics to prevent the risk of fire or explosion. Because it may be volatile, if the storage temperature is too high, it is easy to cause volatile loss, and volatile gases accumulate in a limited space, which also increases safety hazards.
Furthermore, this substance may be harmful to the environment. During transportation, make sure that the packaging is intact and free of leakage. If it leaks, or pollutes soil and water bodies, it will endanger the ecology. Packaging materials should have good sealing and corrosion resistance, and can resist package damage caused by external factors.
The means of transportation should also be properly selected. Those with corresponding qualifications for the transportation of hazardous chemicals should be selected, and the transportation equipment must have protective and emergency treatment devices. In case of sudden leakage and other situations, measures can be taken in time to reduce the harm.
During the handling process, the operation should be light and slow to prevent the package from cracking due to impact and drop. Operators should also take good protection, wearing protective clothing, protective gloves and goggles, etc., to avoid physical damage caused by contact.
The storage period should also be paid attention to. Regular inspection of its character and quality. If it exceeds the storage period or deteriorates, it should not be disposed of at will. Handle it according to the prescribed procedures to ensure the safety of storage and transportation.
What are the potential hazards of 3-bromo-2,4-difluoronitrobenzene to the environment and human body?
3-Chloro-2,4-diethylphenyl has the following potential hazards to the environment and human body:
Hazards to the environment
1. ** Aquatic ecological hazards **: If this substance enters the water body, it may cause toxicity to aquatic organisms. Because of its special chemical structure, it contains chlorine atoms and specific alkyl structures, or it may interfere with the physiological processes of aquatic organisms. Such as hindering the respiratory and metabolic systems of fish, causing breathing difficulties and slow growth of fish; for plankton, it may affect their photosynthesis and reproductive capacity, thereby destroying the balance of the food chain of the entire aquatic ecosystem.
2. ** Soil ecological hazards **: When this substance remains in the soil, it will change the chemical properties of the soil. It may inhibit the growth and activity of beneficial microorganisms in the soil, such as nitrifying bacteria, nitrogen-fixing bacteria, etc., which are essential for nutrient cycling in the soil and plant growth. Once their activity is inhibited, soil fertility decreases, affecting the healthy growth of plants, resulting in reduced crop yield and other consequences.
Harm to human body
1. ** Harm of skin contact **: After human skin is exposed to 3-chloro-2,4-diethylphenyl, it may cause skin irritation symptoms. This is because the chemical groups of the substance may react with the proteins or lipids of skin cells, causing the skin to appear red, swollen, itchy, painful, and even cause skin allergies in severe cases, such as blisters and erosion.
2. ** Respiratory inhalation hazard **: If it is inhaled into the body through breathing, it will cause irritation and damage to the respiratory tract. It may irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure to the environment containing this substance may damage lung tissue and increase the risk of respiratory diseases, such as chronic obstructive pulmonary disease, asthma, etc.
3. ** Potential carcinogenic and teratogenic risk **: In view of the presence of chlorine atoms in its chemical structure, it is inferred from some studies of similar chemicals that 3-chloro-2,4-diethylphenyl may have potential carcinogenic and teratogenic properties. In animal experiments, some chlorine-containing organic compounds have been proven to induce tumors and affect embryonic development. Although there is no conclusive evidence in human studies, its latent risk cannot be ignored.