3-Bromo-1- (trifluoromethoxy) benzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to the unique properties of bromine atoms and trifluoromethoxy groups in its structure, it can participate in a variety of chemical reactions, and then form various complex organic molecules.
In the field of pharmaceutical chemistry, this is used as a starting material through a series of delicate reactions to prepare compounds with specific biological activities. In the process of many drug development, it plays a cornerstone role, helping to create new drugs to deal with various diseases.
It is also useful in materials science. Through appropriate chemical transformation, it can be introduced into the structure of polymer materials, endowing the materials with excellent properties such as chemical resistance and low surface energy, and expanding the application scenarios of materials, such as in the preparation of special coating materials.
In addition, in the field of pesticide chemistry, pesticide ingredients with high-efficiency insecticidal, bactericidal or herbicidal activities can be synthesized on this basis, providing strong support for agricultural production of pest control and weed control. In short, 3-bromo-1 - (trifluoromethoxy) benzene, with its unique structure, plays an indispensable role in many chemical-related fields, promoting the progress and development of technologies in various fields.

3-Bromo-1- (trifluoromethoxy) benzene is one of the organic compounds. Its physical properties are unique and of great research value.
Looking at its properties, under room temperature and pressure, it is mostly colorless to light yellow transparent liquid. This form is convenient for many chemical reactions to carry out. Because of its good fluidity, it can fully contact the reactants.
Smell it, it has a special smell. Although this smell is difficult to describe accurately, it can be used as one of the characteristics to identify the substance.
As for the boiling point, it is about 180-182 ° C. This boiling point condition allows the substance to realize the transition between liquid and gaseous states in a specific temperature environment. In chemical operations such as distillation and separation, this boiling point property is of great significance. The melting point of
is roughly around -15 ° C. The lower melting point indicates that the substance can still maintain a liquid state in a relatively low temperature environment, showing good low-temperature fluidity. It is a key consideration in some reactions or processes that require low-temperature operation. The density of
is about 1.72 g/cm ³, which is heavier than water. This density characteristic determines its distribution when coexisting with substances with different densities like water, and has an important impact on the stratification and separation operations of substances in related experiments and industrial production.
In terms of solubility, it is slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility characteristic is due to the characteristics of its molecular structure, which makes it well miscible with other organic compounds in the organic system, which is conducive to the progress of organic synthesis reactions. It can be used as a solvent or reactant to participate in many organic chemical reactions.
In summary, the many physical properties of 3-bromo-1- (trifluoromethoxy) benzene lay the foundation for its application in organic synthesis, chemical production and other fields, and are of great significance for in-depth research and rational use of this substance.

The synthesis of 3-bromo-1- (trifluoromethoxy) benzene is an important topic in the field of organic synthesis. The synthesis pathways reported in the past are mostly based on classical organic reaction principles.
One method can be started from 3-bromophenol. Shilling 3-bromophenol reacts with bases, such as sodium hydroxide, in suitable solvents, such as N, N-dimethylformamide (DMF), and phenolic hydroxyl groups react with bases to form phenoxanions. Then, a trifluoromethylating reagent, such as trifluoromethyl sulfonyl fluoride (CF < unk > SO < unk > F), is added. The phenoxy anion nucleophilic attacks the sulfur atom of the trifluoromethylating reagent, and forms a C-O-CF < unk > bond through nucleophilic substitution reaction, thereby obtaining the target product 3-bromo-1 - (trifluoromethoxy) benzene. In this process, the reaction temperature, the amount of base, and the activity of the trifluoromethylating reagent all have a significant impact on the reaction yield and selectivity. If the temperature is too high, it may cause an increase in side reactions; if the amount of base is insufficient, the phenol hydroxyl group cannot be completely converted into phen
Another synthesis method can be started from 3-bromoaniline. First, through the diazotization reaction, 3-bromoaniline is reacted with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. Then add a trifluoromethoxy reagent, such as copper trifluoromethoxy (CuOCF 🥰), the diazoyl group is replaced by the trifluoromethoxy group to form 3-bromo-1 - (trifluoromethoxy) benzene. This path requires strict control of the diazotization reaction temperature, usually 0-5 ° C, to prevent the decomposition of diazonium salts. The preparation and stability of trifluoromethoxy copper are also related to the success or failure of the reaction. When preparing trifluoromethoxy copper, the raw materials and reaction conditions used need to be carefully controlled to ensure its activity and stability, and then ensure the smooth progress of the substitution reaction.
These two types of synthesis methods, although based on different starting materials and reaction mechanisms, are all dedicated to the efficient and highly selective synthesis of 3-bromo-1- (trifluoromethoxy) benzene. During the synthesis process, the precise regulation of the reaction conditions, as well as the separation and purification of the intermediate products in each step, are the keys to obtaining high-purity target products.

3-Bromo-1 - (trifluoromethoxy) benzene is also an organic compound. When storing and transporting, be sure to pay attention to many matters.
Bear the brunt, the storage place must be cool and dry. Cover so compounds are afraid of moisture and heat. If placed in a warm and humid place, they may deteriorate and affect their chemical properties. Just like the ancient people's collections, you must find a dry place to keep the items from breaking down for a long time.
Furthermore, it needs to be separated from oxidants, alkalis and other substances. This is because the compound encounters them and is prone to chemical reactions or dangerous. Just like water and fire are incompatible, the two types of chemicals cannot be coexisted in the same room.
During transportation, the packaging must be tight. Appropriate packaging materials should be selected to ensure that they are not damaged by bumps and collisions during transportation. In ancient times, precious utensils were also wrapped in thick objects to prevent damage. The same is true.
At the same time, the transportation vehicle should also be clean and free of debris, so as not to mix with impurities and contaminate this compound. And during driving, the temperature should be properly controlled to avoid high temperatures.
In addition, relevant operators must be familiar with the characteristics of this compound and emergency treatment methods. In the event of an accident such as a leak, measures can be taken quickly to reduce the damage. For example, in ancient times, soldiers must be familiar with the art of war before they can be in danger.
In conclusion, the storage and transportation of 3-bromo-1- (trifluoromethoxy) benzene requires more attention to the environment, isolation, packaging, personnel, etc., in order to ensure its safety and avoid harm.

The market price range of 3-bromo-1- (trifluoromethoxy) benzene is difficult to generalize. Its price often varies due to a variety of factors, and the market fluctuates frequently.
First, the cost of raw materials for production has a significant impact on its price. If the raw materials required for the synthesis of this compound are scarce or difficult to prepare, the price will be high, which in turn will increase the price of 3-bromo-1- (trifluoromethoxy) benzene; conversely, the supply of raw materials is abundant, the cost is low, and the product price will fall accordingly.
Second, the market supply and demand trend is also key. If the demand for this product increases sharply at a certain time, such as research and development and production in the fields of pharmaceuticals and materials science are urgently needed, and the supply is difficult to respond for a while, the price will rise; if the market demand is weak and the supply is excessive, the price will easily drop.
Third, the difficulty and advanced of the preparation process also affect the price. Complex and high-cost processes require more manpower, material resources and technical investment, and the price of the product will be high; if the process is advanced, efficient and the cost is controllable, the price may be maintained at a relatively low level.
Fourth, macroeconomic conditions and policies and regulations also play a role. In the economic boom, various industries are active, and demand drives prices; conversely, in the economic downturn, demand is sluggish, and prices are pressured. Policies and regulations have strict requirements on environmental protection and safe production, and high compliance costs for enterprises will also push up product prices.
In summary, the market price range of 3-bromo-1- (trifluoromethoxy) benzene fluctuates very frequently. To know the exact price, it is necessary to carefully observe the market dynamics in real time, and consider various factors such as raw materials, supply and demand, processes and policies. Roughly speaking, the price per gram may range from tens to hundreds of yuan. This is only an approximate number and cannot be taken as a conclusion.