3-Bromo-1,2-difluoro-4-methoxybenzene has a wide range of uses in the field of organic synthesis.
First, it can be used as a pharmaceutical intermediate. In the process of pharmaceutical creation, it is often necessary to construct compounds with specific structures. This compound contains functional groups such as bromine, fluorine and methoxy, and can introduce other key structural fragments through various chemical reactions, such as nucleophilic substitution and coupling reactions, to form drug molecules with specific biological activities. For example, through palladium-catalyzed coupling reactions, bromine atoms can be linked to nucleophiles containing carbon, nitrogen, and oxygen, laying the foundation for the construction of complex pharmaceutical structures.
Second, it is also useful in the field of materials science. Due to its unique molecular structure, the material is endowed with special physical and chemical properties. It can be used to prepare organic materials with special photoelectric properties, such as organic Light Emitting Diode (OLED) materials. The introduction of fluorine atoms may improve the electron transport properties, stability and solubility of the material, thereby enhancing the performance of OLED devices, such as luminous efficiency and lifespan.
Third, it also has potential value in pesticide synthesis. After modification and transformation, pesticide components can be derived that have high inhibitory or killing effects on specific pests or pathogens. Its fluorine and bromine functional groups may enhance the biological activity, environmental stability and selectivity of pesticides, providing an opportunity for the development of new high-efficiency and low-toxicity pesticides.
All of these, the unique structure and reactivity of 3-bromo-1,2-difluoro-4-methoxybenzene are important synthetic building blocks in many fields such as medicine, materials, and pesticides, promoting technological innovation and development in various fields.

3-Bromo-1,2-difluoro-4-methoxybenzene is one of the organic compounds. Its physical properties are as follows:
First appearance, at room temperature, it is often colorless to light yellow liquid, clear and transparent, and has a shiny appearance. This state is determined by the intermolecular force and structure, and the molecular interaction is moderate, causing it to exist in the liquid state at room temperature.
The second and boiling point are about a certain temperature range. Because the molecule contains bromine, fluorine, methoxy and other groups, it increases the intermolecular attraction, so that gasification requires higher energy, and the boiling point can be increased. However, the exact boiling point value will vary slightly due to experimental conditions and impurities and other factors.
In addition, the melting point is also in a specific temperature range, which requires specific energy conditions when the molecules are arranged in an orderly manner into a solid structure. Each atom in the molecular structure interacts with the group to determine the lattice energy, which in turn affects the melting point.
When it comes to density, it is relatively larger than water. Under standard conditions, the mass per unit volume has a certain value. This is due to the type and quantity of atoms in the molecule, especially the relative mass of bromine and fluorine atoms, which leads to high density.
In terms of solubility, it is slightly soluble in water. Because it is an organic compound, and water is a highly polar solvent, although this compound contains polar fluorine and methoxy groups, it is still strongly non-polar as a whole. According to the principle of "similar miscibility", it is slightly soluble in water. In organic solvents, such as ethanol, ether, dichloromethane, etc., the solubility is quite good. Because the polarity of organic solvents is similar to that of the compound, similar interactions can be formed between molecules, which is conducive to its dissolution.
It is also volatile and has a certain volatility. In an open environment, molecules will escape from the liquid surface to the gas phase. This volatility is restricted by factors such as temperature and vapor pressure. When the temperature increases, the vapor pressure increases, and the volatility increases.
The physical properties of this compound are of great significance in the fields of organic synthesis and materials science. Synthesizers can choose suitable separation and purification methods according to their boiling point, solubility and other properties. For material preparation, its density, volatility and other properties affect material properties and processing technology.

The preparation of 3-bromo-1,2-difluoro-4-methoxybenzene can be started from the following route.
First, p-methoxybenzene is used as the starting material. The reaction of p-methoxybenzene with fluorinated reagents is carried out by fluorination. The fluorinated reagent can be selected from Selectfluor, etc. In an appropriate solvent such as acetonitrile, an appropriate amount of base such as potassium carbonate is added. Under heating conditions, fluorine atoms can be introduced into the benzene ring to generate 2-fluoro-4-methoxybenzene. In this step, the reaction temperature and the amount of fluorinated reagents need to be strictly controlled to maximize the yield of the target product and reduce the generation of polyfluorinated by-products.
Next, 2-fluoro-4-methoxybenzene is brominated. Liquid bromine can be used as a bromination reagent to react in solvents such as dichloromethane under the action of catalysts such as iron powder or iron tribromide. Bromine atoms will selectively enter the position of ortho or para-position with methoxy groups on the benzene ring. Under these conditions, 3-bromo-2-fluoro-4-methoxybenzene is mainly generated due to the positioning effect of fluorine atoms. Care should be taken to control the amount of bromine and the reaction time to avoid excessive bromination.
Finally, 3-bromo-2-fluoro-4-methoxybenzene is fluorinated again. Under the conditions similar to the first step of fluoridation, Selectfluor is used as the fluorinated reagent, and a fluorine atom is introduced into the benzene ring in a suitable base and solvent system to obtain 3-bromo-1,2-difluoro-4-methoxybenzene. After the reaction, the product is purified by conventional separation methods such as extraction, distillation, column chromatography, etc., to obtain a high-purity target product. Throughout the process, the conditions of each step of the reaction are controlled and the product is purified, which is crucial for the final achievement of the target product.

3-Bromo-1,2-difluoro-4-methoxybenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this compound should be placed in a cool and dry place. Cover because it is sensitive to heat, if it is in a high temperature environment, it may cause its chemical properties to change and cause adverse reactions such as decomposition. And it is necessary to keep away from fire and heat sources to prevent fire hazards. Furthermore, it should be sealed and stored to avoid contact with air, moisture, etc. Oxygen in the air may cause oxidation, moisture may cause reactions such as hydrolysis, which will damage the purity and quality of the compound. The storage place should also be separated from oxidizing agents, acids, alkalis, etc. Due to the chemical activity of the compound, it can be mixed with or react violently.
As for transportation, there are also many precautions. It is necessary to ensure that the packaging is complete and well sealed to avoid leakage during transportation. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment, just in case. The transportation process must be protected from sun exposure, rain, and high temperature. Summer transportation should be carried out in the morning and evening to avoid high temperature periods. When handling, it should be handled lightly to prevent damage to packaging and containers. This compound may be toxic and corrosive. If the packaging is damaged, the leakage may endanger the safety of personnel and the environment.
In conclusion, in the storage and transportation of 3-bromo-1,2-difluoro-4-methoxybenzene, many aspects such as temperature, humidity, sealing, and isolation from other substances must be treated with caution to ensure the stability of its properties and the safety of personnel and the environment.

3-Bromo-1,2-difluoro-4-methoxybenzene, which is in the market, its price range is difficult to determine. The change in the price depends on various factors, and so on.
First, the difficulty of its preparation has a lot to do with it. If the preparation method is complicated, requires multiple processes, and the materials used are rare and difficult to find, and the equipment and medicines used need to be exquisite, and the cost of manpower and material resources is huge, the price will be high. If the preparation method is simple, and the materials used are common and easy to obtain, the price may be slightly cheaper.
Furthermore, the supply and demand situation in the market is also the main reason. If this product is in high demand in various industries, such as medicine, chemical industry, etc., but the supply is limited, the supply is in short supply, and the price must rise. If the supply exceeds the demand, the manufacturer will sell the product or reduce the price to promote it.
Also, the place where it is produced also affects its price. In different places, due to the difference in raw material costs, labor prices, and tax policies, the cost of producing this product is different, and the price is also different.
There are differences in quality, which are related to the price. Those with excellent quality, few impurities, and high purity should be more expensive than those with poor quality.
In summary, the price of 3-bromo-1,2-difluoro-4-methoxybenzene in the market may vary greatly due to the difficulty of preparation, supply and demand conditions, different origins, and quality. It is difficult to determine its exact price range.