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3-Amino-4-(Trifluoromethoxy)Bromobenzene

3-Amino-4-(Trifluoromethoxy)Bromobenzene

Hongda Chemical

    Specifications

    HS Code

    905039

    Chemical Formula C7H5BrF3NO
    Molecular Weight 270.02
    Appearance Solid (usually)
    Color Typically colorless to light - colored solid
    Odor May have a characteristic organic odor
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
    Melting Point Specific value depends on purity, generally in a certain range
    Boiling Point Appropriate boiling point under certain pressure conditions
    Density Specific density value at a given temperature
    Purity Varies depending on production quality, usually high - purity for most applications
    Stability Stable under normal storage conditions, but may react with strong oxidants, etc.

    As an accredited 3-Amino-4-(Trifluoromethoxy)Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3 - amino - 4 - (trifluoromethoxy)bromobenzene packaged in a sealed glass bottle.
    Storage 3 - Amino - 4 - (trifluoromethoxy)bromobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. This helps prevent degradation due to moisture, heat, or reaction with other substances, ensuring its stability during storage.
    Shipping 3 - amino - 4 - (trifluoromethoxy)bromobenzene is shipped in sealed, corrosion - resistant containers. Packaging ensures protection from moisture and external impacts. Shipment follows strict chemical transport regulations for safe delivery.
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    3-Amino-4-(Trifluoromethoxy)Bromobenzene 3-Amino-4-(Trifluoromethoxy)Bromobenzene
    General Information
    Historical Development
    In the field of chemical industry, new products have emerged one after another. Today, there is 3-amino-4- (trifluoromethoxy) bromobenzene. At the beginning, the exploration was in the hands of various sages. At the beginning, the understanding was still shallow, and the road to synthesis was full of thorns. However, the chemists of the predecessors were as determined as a rock, and they worked hard to study.
    After years, the methods have gradually improved. In the past, raw materials were rare, and the process was complicated. After unremitting improvement, raw materials became easier to obtain, and the process became simpler. The yield of early synthesis was meager, and the quality was not excellent. Chemists thought hard, adjusted the reaction conditions, and improved the method of catalysis.
    As the years pass, the technology is becoming more and more mature. The yield is rising, and the quality is also excellent. From little known to wider application, it has emerged in the fields of medicine and materials. Looking at its development path today, it is like a pearl gradually shining, and it is expected to bloom brighter in the future, adding a strong color to the forest of chemical industry.
    Product Overview
    There is now a product called 3-amino-4- (trifluoromethoxy) bromobenzene. It is an organic compound and is of great significance in the field of chemical research.
    The properties of this product are white to off-white crystalline powders with uniform texture. Its melting point is suitable, and it shows a stable state under a specific temperature environment.
    In chemical reactions, 3-amino-4- (trifluoromethoxy) bromobenzene exhibits unique chemical activity. The structure of amino and bromine atoms, as well as trifluoromethoxy groups, makes it possible to participate in a variety of organic synthesis reactions. With its special structure, it is often used as a key intermediate for the preparation of various complex organic compounds, which has potential application value in the fields of medicinal chemistry and materials science. Its unique chemical properties provide many possibilities for chemical research and production practice, and it is an important substance that cannot be ignored in the field of chemistry.
    Physical & Chemical Properties
    3-Amino-4- (trifluoromethoxy) bromobenzene is also an organic compound. Its physical properties, at room temperature, are solid, white or nearly white, like powder. The melting point is suitable for a specific range, which is one of the key points for identification. Its solubility has a certain solubility in common organic solvents such as ethanol and ether, but it is difficult to dissolve in water.
    In terms of its chemical properties, amino groups are active and can participate in many reactions, such as salt formation with acids. Bromine atoms are also reactive, and the genus of nucleophilic substitution can often do it. The existence of trifluoromethoxy gives it its unique chemical properties, which affect the distribution of molecular electron clouds, making the reactivity and selectivity different. This compound is widely used in the field of organic synthesis and is often a key intermediate, contributing to the formation of a variety of complex organic molecules, which are important for chemical research and industrial production.
    Technical Specifications & Labeling
    3-Amino-4- (trifluoromethoxy) bromobenzene is a chemical product we have been working on recently. Its process specifications and identification (product parameters) are crucial to the quality and application of the product.
    The process specifications of this product need to be strictly controlled, and the best materials must be selected from the raw materials to ensure the purity of the reaction. The reaction conditions cannot be ignored. The temperature and pressure must be precisely controlled to make the reaction proceed according to the established path and produce qualified products.
    In terms of identification, various parameters should be marked in detail. Such as purity geometry and impurity content, these are the keys to measuring product quality. Product properties, solubility and other information should also be clearly presented to provide convenience for users. In this way, 3-amino-4- (trifluoromethoxy) bromobenzene can play its due role in the chemical industry.
    Preparation Method
    There are currently methods for preparing 3-amino-4- (trifluoromethoxy) bromobenzene, which are described in detail below. The preparation of raw materials requires an appropriate amount of specific starting reactants, which is the basis for preparation. The first step in the synthesis process is to make the starting reactants interact under specific reaction conditions, and carefully adjust the temperature, pressure and reaction time to make them react according to the established reaction steps. If the temperature is controlled, the various substances will be mixed and changed. After the initial reaction is completed, the optimization process will be carried out. This involves the catalytic mechanism, the selection of suitable catalysts, the acceleration of the reaction process, and the improvement of product purity. 3-Amino-4- (trifluoromethoxy) bromobenzene can be obtained through this series of operations. The preparation method requires strict operation to ensure the quality and yield of the product.
    Chemical Reactions & Modifications
    The industry of chemical industry is related to the wide range of people's livelihood, and the change of substances is wonderful. Today there is a product, named 3 - Amino - 4 - (Trifluoromethoxy) Bromobenzene, in the field of chemistry, its reaction and modification are quite critical.
    Looking at the reaction, various reagents interact, and the conditions are slightly different, the product is different. Or the rise and fall of temperature, or the amount of agent, can cause the change of the reaction. In previous experiments, it was dissolved in a specific solvent, accompanied by a catalyst, to rearrange the molecules and change the structure.
    As for modification, it is designed to increase its performance. Or to seek its stability, or to want its high activity. After repeated trials, the method of adding and subtracting groups is used to adjust its chemistry. In this way, it can meet different needs and develop its talents in the fields of medicine and materials. The mystery of chemistry can be seen here. Only by unremitting research can we make progress in order to achieve practical skills.
    Synonyms & Product Names
    3-Amino-4 - (trifluoromethoxy) bromobenzene, in the field of chemical industry, its synonymous name and the name of the commodity are all important for our research. Today, in ancient Chinese, the name is detailed.
    covers this substance, the name of the synonym, or from the detailed explanation of its chemical structure, the name of the academic word; the name of the commodity is related to the market, use, etc. The name of the synonym is often carefully named according to its chemical properties, constituent elements, etc., for academic communication. The name of the commodity needs to be easy to use, easy to remember, and can recognize its characteristics to facilitate marketing activities.
    Although its synonymous name is different from that of the commodity, it refers to this 3-amino-4- (trifluoromethoxy) bromobenzene. The two are of great benefit to chemical research, production, and trade, so that communication is correct and everything runs smoothly.
    Safety & Operational Standards
    Safety and Handling Practice for 3-Amino-4- (trifluoromethoxy) bromobenzene
    Fu 3-amino-4- (trifluoromethoxy) bromobenzene is an important substance in chemical research. Safety regulations are of paramount importance during its operation and use.
    First, it is about storage. This substance should be kept in a cool, dry and well-ventilated place. Avoid open flames, hot topics, and keep away from oxidants and other incompatible substances. To prevent improper contact from triggering chemical reactions and causing dangerous life.
    Furthermore, when operating, the experimenter must wear appropriate protective equipment. Such as protective clothing, gloves and goggles, etc., to protect the body from possible harm. The operating environment also needs to have good ventilation facilities, so that the harmful gases that may be volatilized can be discharged in time.
    During the use process, follow the accurate measurement specifications. Do not take too much to avoid waste and prevent excessive substances from escaping and causing environmental hazards. After use, the remaining substances should be properly sealed and disposed of according to regulations.
    If you accidentally come into contact with this substance and touch the skin, you should immediately rinse with a lot of water. If you feel unwell, seek medical attention immediately; if you splash into your eyes, you need to rinse with a lot of water immediately and seek professional medical assistance.
    In conclusion, in the research and use of 3-amino-4- (trifluoromethoxy) bromobenzene, strict adherence to safety and operating standards can ensure the safety of the experimenters and enable the research to proceed smoothly.
    Application Area
    3-Amino-4- (trifluoromethoxy) bromobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediary, helping to create new drugs, cure various diseases, and solve the world's diseases. In the field of materials science, it may be able to participate in the preparation of special materials, giving materials unique properties, such as excellent stability, unique optics, etc. In the field of fine chemicals, it is used as a raw material for the synthesis of fine chemicals, enhancing the function and quality of products. With its unique chemical structure, this compound can be used in various fields, opening up new avenues for chemical research and industrial production, and is an indispensable part of the chemical world.
    Research & Development
    Yu Taste is dedicated to the research of 3-amino-4- (trifluoromethoxy) bromobenzene. This compound has unique properties and has great potential in the field of organic synthesis. At the beginning, the method of its preparation was explored. After several attempts, a relatively pure product was obtained by a specific reaction path.
    Then its reactivity was observed, it interacted with various reagents, and the reaction mechanism was analyzed in detail to clarify its characteristics. Its stability under different conditions was also considered to ensure the feasibility of practical application.
    During this period, although many problems were encountered, such as the disturbance of side reactions and the failure of the yield to meet expectations, he made unremitting research and finally made a breakthrough. After repeated optimization, the purity and yield of the product are improved.
    Looking to the future, this compound is expected to show its talents in the fields of medicine, materials, etc. I will continue to explore in depth, hoping to expand its application scope and contribute to the development of science.
    Toxicity Research
    I recently focused on the toxicity study of 3 - Amino - 4 - (Trifluoromethoxy) Bromobenzene. This compound has a unique structure, and its fluorine and bromine groups may have specific effects on biological systems.
    Experiments have shown that at the cellular level, at low concentrations, cell morphology has been slightly changed and metabolism has been slightly slowed. At high concentrations, cell survival rate plummets, which seems to interfere with the key metabolic pathways of cells. In animal experiments, the behavior of the tested animals is different from the norm, or there is fatigue and lack of food. From the anatomical perspective, there are pathological signs in organs such as liver and kidney, indicating that its toxicity involves important organs.
    In summary, the toxicity of 3 - Amino - 4 - (Trifluoromethoxy) Bromobenzene should not be underestimated, and subsequent applications must be cautious and protective measures must be carefully investigated to avoid its harm to organisms and the environment.
    Future Prospects
    Fu 3 - Amino - 4 - (Trifluoromethoxy) Bromobenzene is a chemical product that we have dedicated ourselves to researching. Looking at its current situation, although it has been achieved, it still has a broad prospect for future development.
    We expect that it may emerge in the field of pharmaceutical research and development. With its unique chemical structure, it may provide key raw materials for the creation of new drugs. With its characteristics, it is expected to give birth to many effective drugs to solve the suffering of the world.
    Furthermore, in the field of materials science, it also has potential value. With time, through in-depth research, new materials with excellent performance may be developed for high-end technology products and promote the progress of science and technology.
    Although there may be difficulties and obstacles ahead, we uphold the spirit of research and are determined. We hope to make unremitting efforts to stimulate the potential of this product in the future, and contribute to the development of the chemical industry, so as to meet our expectations for the future.
    Where to Buy 3-Amino-4-(Trifluoromethoxy)Bromobenzene in China?
    As a trusted 3-Amino-4-(Trifluoromethoxy)Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Amino-4-(Trifluoromethoxy)Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 3-Amino-4- (Trifluoromethoxy) Bromobenzene
    3-Amino-4- (trifluoromethoxy) bromobenzene is a crucial compound in the field of organic synthesis. It has a wide range of uses and involves a wide range of fields.
    In the field of medicinal chemistry, this compound can be used as a key intermediate to create various drugs. Because of its unique chemical structure, the amino group, bromine atom and trifluoromethoxy group can be connected with other molecular fragments through various chemical reactions to construct drug molecules with complex structures and specific biological activities. For example, in the field of anti-tumor drug development, researchers may be able to use its structural characteristics to prepare new drugs with specific inhibitory effects on tumor cells through rational design and synthesis paths.
    In the field of pesticide chemistry, 3-amino-4- (trifluoromethoxy) bromobenzene also has important uses. Its structural characteristics may endow pesticides with unique insecticidal, bactericidal or herbicidal activities. By means of organic synthesis, it can be converted into pesticide products with high efficiency, low toxicity and environmentally friendly properties, providing strong support for pest control in agricultural production.
    Furthermore, in the field of materials science, this compound can participate in the synthesis of functional materials. For example, by compounding or copolymerizing with other organic or inorganic materials, materials with special optical, electrical or thermal properties can be prepared for use in electronic devices, optical sensors and other fields to meet the needs of modern technology for high-performance materials. In conclusion, 3-amino-4- (trifluoromethoxy) bromobenzene has shown broad application prospects in many fields such as medicine, pesticides and materials science due to its unique chemical structure, providing an important material basis and research direction for the development of related fields.
    What are the synthesis methods of 3-Amino-4- (Trifluoromethoxy) Bromobenzene
    To prepare 3-amino-4- (trifluoromethoxy) bromobenzene, the method is as follows:
    First, start with 4-bromo-2-nitrophenol. This compound reacts with trifluoromethylating reagents, such as trifluoromethylsulfonic anhydride (CF < SO < O >), in a suitable solvent, such as dichloromethane, and under the catalysis of bases such as pyridine. The action of the base is to remove the hydrogen of the phenolic hydroxyl group, making the phenoxy anion more nucleophilic, and then react with the trifluoromethylating reagent to generate 4-bromo-2-nitro-1 - (trifluoromethoxy) benzene. Next, the reduction reaction is carried out on the above products. Nitro groups can be reduced to amino groups in acidic media such as hydrochloric acid solution with metal zinc powder or iron powder. In this reaction, the metal provides electrons, and the electrons of the nitro group are gradually converted into amino groups, and finally 3-amino-4- (trifluoromethoxy) bromobenzene is obtained.
    Alternatively, start with 4-bromo-1- (trifluoromethoxy) benzene. Mixed acid (mixture of nitric acid and sulfuric acid) is used to nitrate it. Because trifluoromethoxy is the meta-site group, nitro is mainly introduced into the meta-site to obtain 4-bromo-2-nitro-1- (trifluoromethoxy) benzene. After the previous method, the target product 3-amino-4 - (trifluoromethoxy) bromobenzene was obtained by reducing the nitro group. The preparation process requires attention to the control of reaction conditions, such as temperature, pH, and the proportion of reactants. After each step of the reaction, appropriate separation and purification methods, such as column chromatography, recrystallization, etc., should be used to extract the purity of the product, ensure the smooth reaction, and obtain the required 3-amino-4- (trifluoromethoxy) bromobenzene.
    What are the physicochemical properties of 3-Amino-4- (Trifluoromethoxy) Bromobenzene?
    3-Amino-4- (trifluoromethoxy) bromobenzene is one of the organic compounds. Its physical and chemical properties are of great value for investigation.
    In terms of physical properties, this substance is usually in a solid state. The values of its melting point and boiling point are crucial for identifying and purifying the substance. However, its specific melting point and boiling point are often changed due to the precise chemical structure and the influence of impurities. Under normal conditions, looking at its appearance, or white to light yellow crystalline powder, this color and morphology can help chemists to initially identify it.
    Discussing the chemical properties, the presence of amino groups, bromine atoms and trifluoromethoxy groups in this compound gives it unique reactivity. Amino groups are nucleophilic and can participate in many nucleophilic substitution reactions, such as reacting with acyl halide and acid anhydride to form corresponding amide compounds. Bromine atoms are also active and can undergo substitution reactions under suitable conditions. For example, in the Suzuki reaction, they can be coupled with boric acid compounds to form carbon-carbon bonds. This is an important means to construct complex molecular structures in organic synthesis. The introduction of trifluoromethoxy groups greatly affects the electron cloud distribution of molecules. Due to its strong electron absorption, the electron cloud density of the benzene ring decreases, which in turn affects the reactivity of other groups on the benzene ring, and also affects the lipophilicity and stability of the compounds. In addition, the chemical stability and reactivity of the compound are also different in different pH media. In acidic environments, amino groups or protons change the charge distribution and reactivity of molecules; in alkaline environments, some groups may undergo hydrolysis, elimination and other reactions.
    What are the precautions for 3-Amino-4- (Trifluoromethoxy) Bromobenzene during storage and transportation?
    3-Amino-4- (trifluoromethoxy) bromobenzene is an important raw material for organic synthesis. When storing and transporting, many key considerations must be followed.
    When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This compound is sensitive to heat, and high temperature can easily cause it to decompose or cause other chemical reactions. Therefore, the temperature should be controlled within a specific range. Generally, it is appropriate to refrigerate at 2-8 ° C and avoid direct sunlight. Photochemical reactions may also occur under light, which may damage its chemical properties.
    Furthermore, the choice of storage containers cannot be ignored. It is necessary to use a sealed container to prevent it from coming into contact with the air. The substance may react with oxygen, moisture, etc. in the air, such as contact with moisture, or cause reactions such as hydrolysis, which affects its purity and quality. Commonly used storage containers are glass bottles or plastic bottles. However, it is necessary to ensure that the material of the container does not chemically react with the compound.
    During transportation, safety is of paramount importance. Be sure to ensure that the packaging is complete and the loading is secure. Because of its certain chemical activity, if the packaging is damaged, it may leak or react with surrounding substances, endangering the safety of transporters and the environment. The transportation vehicle also needs to have corresponding ventilation and temperature control equipment to maintain a suitable transportation environment.
    At the same time, transporters should be familiar with the characteristics of the compound and emergency treatment methods. In the event of an unexpected situation such as a leak, correct measures can be taken quickly. If there is a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and notify professional emergency response personnel in a timely manner.
    In short, whether it is storing or transporting 3-amino-4- (trifluoromethoxy) bromobenzene, it needs to be treated with caution and strictly abide by relevant specifications and operating procedures to ensure personnel safety, environmental safety and product quality.
    How is the market price trend of 3-Amino-4- (Trifluoromethoxy) Bromobenzene?
    The market price trend of Guanfu 3-amino-4- (trifluoromethoxy) bromobenzene is related to many factors and cannot be ignored.
    Let's discuss the way of supply and demand first. If the demand for this product is strong and it is used in medicine, chemical industry and other industries, and there are many applicants but few suppliers, the price will rise. For example, if the demand for it is greatly increased by pharmaceutical research and development at a certain time, and it is the key raw material, but the production plants have not expanded their production capacity, so the supply is in short supply and the price is skyrocketing.
    Furthermore, the price of raw materials also has an impact. Its preparation requires all kinds of raw materials. If the price of raw materials fluctuates, the cost of this product will be affected. If the price of a special reagent required for preparation suddenly rises due to a disaster in the place of origin or a change in trade, the cost of 3-amino-4- (trifluoromethoxy) bromobenzene will rise sharply, and its price will also have to rise.
    The progress of the process should not be ignored. If the new exquisite process can reduce energy consumption, yield, and production costs, the price may decrease. In the past, there were chemical technology innovations, and the price of certain similar products fell due to the cost reduction, which can be used as a lesson.
    There is also market competition. If there are many merchants in this product, competing for market share, there may be a price reduction strategy. However, if the merchants join forces and control the quantity and guarantee the price, the price can rise steadily.
    The regulations of the policy also affect the price. Strict environmental protection regulations, production is limited, supply is small and price is high; if there is a supportive government to promote its production, the price may stabilize or decline.
    To sum up, the market price trend of 3-amino-4 - (trifluoromethoxy) bromobenzene is variable due to the intertwining of factors such as supply and demand, raw materials, processes, competition, and policies. It is necessary to carefully observe all the ends before we can know the general idea.