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3-Amino-4-Chlorotrifluoromethylbenzene

3-Amino-4-Chlorotrifluoromethylbenzene

Hongda Chemical

Specifications

HS Code

132741

Chemical Formula C7H5ClF3N
Molecular Weight 195.57
Appearance Solid or liquid (depending on conditions)
Physical State At Room Temp Typically solid
Boiling Point Data varies, around 200 - 220°C approximately
Melting Point Specific value needed from more precise sources
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, acetone
Density Data required from specific references
Flash Point Needs experimental determination

As an accredited 3-Amino-4-Chlorotrifluoromethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - amino - 4 - chlorotrifluoromethylbenzene packaged in a sealed plastic bottle.
Storage 3 - amino - 4 - chlorotrifluoromethylbenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to degradation. Store separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping 3 - amino - 4 - chlorotrifluoromethylbenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported with care, following strict chemical safety regulations to prevent leakage and ensure safe delivery.
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3-Amino-4-Chlorotrifluoromethylbenzene 3-Amino-4-Chlorotrifluoromethylbenzene
General Information
Historical Development
The historical evolution of 3-amino-4-chlorotrifluoromethylbenzene is an important part of chemical research. In the past, organic synthesis was not as delicate as it is today, and scholars have gone through hardships to explore this compound. At first, the synthesis method was simple, the yield was low, and there were many impurities. However, scholars were not discouraged and worked tirelessly.
With the passage of time, the chemical theory became more and more perfect, and the experimental skills were also improved. New catalysts and new reaction paths gradually emerged. The difficult reaction conditions of the past can now be properly regulated. The steps for synthesizing this compound are gradually simplified, the yield can be improved, and the purity is also guaranteed. From the initial exploration to the current mature preparation process, the historical evolution of this compound and the progress in the field of chemistry have paved a solid path for subsequent research and application.
Product Overview
3-Amino-4-chlorotrifluoromethylbenzene is an organic compound. It may be a colorless to light yellow liquid with a special odor. This substance is widely used in the field of organic synthesis.
Its preparation method is often through a specific chemical reaction path. With appropriate starting materials, following strict reaction conditions, after several steps of reaction, this compound can be obtained.
In industrial production, attention is paid to the efficiency and purity of the reaction. Reaction parameters such as temperature, pressure, and the proportion of reactants are carefully controlled to ensure the quality and yield of the product.
In terms of application, 3-amino-4-chlorotrifluoromethylbenzene is often a key intermediate in the preparation of drugs, pesticides and other fine chemicals. Due to its unique chemical structure, it endows the products with specific properties and efficacy. It is an indispensable and important substance in the field of organic synthesis.
Physical & Chemical Properties
3-Amino-4-chlorotrifluoromethylbenzene is also an organic compound. Its physical and chemical properties are quite important to those who study chemistry.
This compound, at room temperature, or as a solid, looks at its morphology, color or near-white, fine texture. Its melting point and boiling point are the keys to determine its characteristics. Melting point, so it is known that it is from solid to liquid temperature; boiling point, it is also known that it is from liquid to gas degree.
In terms of solubility, it may have a certain solubility in organic solvents, which has a great impact on its separation, purification and reaction applications.
In the chemical properties, the presence of amino groups, chlorine and trifluoromethyl groups endows them with unique reactivity. Amino groups can participate in nucleophilic reactions, and chlorine atoms can be replaced under appropriate conditions. The strong electron-absorbing properties of trifluoromethyl groups change the electron cloud distribution of the molecule, which affects the overall reaction trend.
All these physicochemical properties are the basis for in-depth understanding of 3-amino-4-chlorotrifluoromethylbenzene and its application in chemical, pharmaceutical and other fields.
Technical Specifications & Labeling
Nowadays, there are chemical substances called 3 - Amino - 4 - Chlorotrifluoromethylbenzene, and its technical specifications and identification (commodity parameters) are of paramount importance. Looking at its technical specifications, it is necessary to clarify the preparation method, from the selection of raw materials, the accurate ratio, and the order of operation, there are rules. The temperature, pressure, and duration of the reaction are all related to the quality of the product. As for the identification (commodity parameters), the color, taste, and state should be detailed, the purity geometry, and the content of impurities, all need to be confirmed. These two, technical specifications and identification (commodity parameters), in 3 - Amino - 4 - Chlorotrifluoromethylbenzene things, such as two wheels of the car, two wings of the bird, lack of a good environment, only strictly observe them, in order to get excellent products.
Preparation Method
3-Amino-4-Chlorotrifluoromethylbenzene is an important organic compound, and its preparation method is very important. In the selection of raw materials, specific halogenated aromatics and amino-containing reagents can be used.
Preparation process is as follows: First, the halogenated aromatics and amino-containing reagents are substituted in a suitable solvent under alkali catalysis. This is a key step, which affects the purity and yield of the product. Then the reaction mixture is separated and purified, such as extraction, distillation, recrystallization and other means to obtain the pure product.
In order to ensure the smooth reaction, the reaction conditions need to be controlled. Temperature should be precisely regulated, too high or too low will affect the reaction process; reaction time should also be appropriate, too short will cause incomplete reaction, too long or increase side reactions. At the same time, the choice and amount of catalyst will also affect the reaction and should be optimized according to the actual situation. In this way, 3-Amino-4-Chlorotrifluoromethylbenzene can be efficiently prepared.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the research of new substances, constant weight reaction and modification. In this sentence 3 - Amino - 4 - Chlorotrifluoromethylbenzene this substance, the reaction of its synthesis is related to various chemical mechanisms. To make it, or through halogenation, amination and other steps. When halogenating, choose a suitable halogenating agent, control its temperature and the amount of agent, so that the chlorine atom is just in a specific position of the benzene ring to form a chlorine substitute.
Then amination, find a suitable amination agent, and use the catalytic force to guide the amino group to a predetermined position, then get 3 - Amino - 4 - Chlorotrifluoromethylbenzene. However, this reaction process may encounter many difficulties. Such as the selectivity of the reaction, it is often difficult to be precise, or by-products are produced, and the yield is not high.
As for modification, in order to expand its use, or add functional groups to change its physical and chemical properties. Or introduce hydrophilic groups to make it applicable in the aqueous phase; or increase its stability to adapt to different environments. This requires fine study of the mechanism and adjustment of the conditions of the reaction in order to achieve the expected modification effect, so that it can have better performance in various fields such as medicine and materials.
Synonyms & Product Names
3-Amino-4-chlorotrifluoromethylbenzene, the synonym and trade name of this substance, has always been valued by the academic community. Its synonyms, either from the detailed analysis of structure or according to its characteristics, are all accurate references to this substance. As for the trade name, it is the logo used by merchants in the market, and it also has unique significance.
Ancient scholars, in the study of material properties, although there is no precision instrument today, but with keen insight and wisdom, they have also gained. Today's 3-amino-4-chlorotrifluoromethylbenzene is widely used in chemical fields. Its synonyms can help researchers communicate accurately, and the trade name is easy to identify in the market.
Looking at its development, with the advancement of science and technology, the cognition of this thing is becoming more and more profound, and synonyms or trade names may also be improved. We chemical researchers should study the synonyms and trade names of this thing in detail, in order to clarify its nature and make the best use of it, and contribute to the progress of chemistry and industry.
Safety & Operational Standards
3-Amino-4-chlorotrifluoromethylbenzene is also a chemical product. For this product, safety and operating standards are essential and should not be ignored.
Where this material is involved in the handling, the operator must first understand its properties. 3-Amino-4-chlorotrifluoromethylbenzene has special chemical properties or responds to other substances, so when operating, choose carefully what comes into contact with it. The device used should also be suitable for this material to prevent damage and leakage, resulting in dangerous conditions.
The operator must keep Tongtai to avoid its gas accumulation. If it is operated in a closed place, the gas accumulation will be dangerous. And the operator in front of the appropriate protective gear, such as chemical protective clothing, gloves, masks, etc., to protect themselves from direct contact with the object, inhaling its air.
Store this thing, there are also rules. It should be placed in a cool, dry, and open place to avoid fire and heat sources. And it needs to be stored separately from things that are easy to respond to, and it should be kept far away to prevent accidents. The reservoir must be firm and sealed to prevent leakage.
In case of leakage, don't panic. The first is to cut off the source, and no fireworks. Quickly order everyone to leave the dangerous area and set up a fence. Operators wear special protective gear and use appropriate methods to discharge. Small leaks should be swept away, placed in the container, and properly placed; large leaks should be embanketed and stored, and then purified by law.
In short, the handling and storage of 3-amino-4-chlorotrifluoromethylbenzene should be carried out according to safety and operating standards, so as to be safe and avoid disasters.
Application Area
3-Amino-4-chlorotrifluoromethylbenzene, this compound has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize drugs with special curative effects to deal with specific diseases, or to improve drug targeting and efficacy. In the field of pesticides, through rational design and transformation, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed to effectively control pests and diseases and ensure a bumper harvest of crops. In the field of materials science, it can participate in the preparation of functional materials, endowing materials with special optical, electrical or thermal properties to meet the needs of high-end scientific and technological fields. Its in-depth research and expansion in various application fields has injected a steady stream of vitality into the development of related industries, and is expected to generate more innovative achievements and practical products for the benefit of human society.
Research & Development
I have been in chemical research for many years, and recently focused on the investigation of 3-amino-4-chlorotrifluoromethylbenzene. This compound has unique characteristics and has potential applications in many fields.
I first studied its structure and properties in detail to understand its chemical activity and reaction tendency. I also explored the method of synthesis. After repeated attempts and improvements, the process was optimized to improve the yield and purity.
In the research, it can be used as a key intermediate in the field of medicine, or it can help create new drugs to fight difficult diseases. In the field of materials science, it may also provide opportunities for the development of high-performance materials.
Looking to the future, we should continue to refine our research and tap its potential. Work with colleagues to promote this compound from the laboratory to practical application, realize its value, and contribute to the development of the chemical field, benefiting society.
Toxicity Research
Those who study poisons in modern times, in 3 - Amino - 4 - Chlorotrifluoromethylbenzene this substance, the toxicity of the study is quite attentive. Cover the rise of chemical industry, such substances are increasing, and their impact on the human body and the environment cannot be ignored.
Detailed examination, the toxicity of 3 - Amino - 4 - Chlorotrifluoromethylbenzene, or the damage of the viscera. After entering the body, it may disturb the luck of qi and blood, and mess with the viscera. Or injure the liver and spleen, causing its function to be impaired; or harm the heart and lungs, making the breath unsmooth.
And this thing is in the environment, and it is not good. Or sewage soil, causing vegetation to be discouraged; or staining the air, causing damage to living beings. Although the amount is small, it can add up to a lot, but it can also cause a great disaster. Therefore, the study of toxicity is related to people's livelihood and cannot be slack. We should use scientific methods to investigate carefully and seek strategies to avoid harm, so as to ensure the well-being of everyone and protect the tranquility of the environment.
Future Prospects
Husband 3 - Amino - 4 - Chlorotrifluoromethylbenzene, it is also a new product of chemistry. I have high hopes in the future of this thing.
Its characteristics are unique, and it is expected to show extraordinary performance in many fields. In today's world of chemistry, new things are emerging one after another, and this product, with its characteristics, may be able to be researched and researched to help people make special effects, and solve the suffering of life. In the field of materials, it may also become the basis of new materials, and the materials can be used with strange properties.
And the way of science, explore. I believe that in time, researchers will be able to deeply explore its secrets, making it more useful and effective. The unseen scene will be enhanced by the 3 - Amino - 4 - Chlorotrifluoromethylbenzene, and the well-being of people will be enhanced.
Where to Buy 3-Amino-4-Chlorotrifluoromethylbenzene in China?
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Frequently Asked Questions

As a leading 3-Amino-4-Chlorotrifluoromethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-amino-4-chlorotrifluoromethylbenzene?
The main use of 3-hydroxy-4-methoxytrimethoxybenzoylbenzene is commonly found in the fields of medicine and chemical industry.
In medicine, its structural properties make it play a key role in drug synthesis. Due to its specific chemical activity and structure, it can be used as a key intermediate in the synthesis of many drugs. For example, some drugs with antibacterial and anti-inflammatory effects, in the synthesis process, 3-hydroxy-4-methoxytrimethoxybenzoylbenzene can undergo a series of chemical reactions and combine with other compounds to shape complex molecular structures with specific pharmacological activities. For example, in the development of therapeutic drugs for specific inflammation, the substance can precisely participate in the reaction and construct molecules with high affinity for inflammation-related receptors, thereby achieving effective suppression of inflammation.
In the chemical industry, it plays an important role in dye synthesis. With its special chromophore and chemical stability, it can become the core raw material for the synthesis of high-quality and high-stability dyes. The dyes synthesized by it are bright and long-lasting, and are widely used in textile, printing and dyeing and other industries. For example, in the textile printing and dyeing process, the use of dyes synthesized from it can make the fabric evenly colored, with bright color, and it is not easy to fade after multiple washes, which greatly enhances the aesthetics and commercial value of the fabric. In addition, in the preparation of some functional materials, it can also be used as a modifier or additive to endow the material with special properties such as oxidation resistance and UV resistance, thus broadening the application range of the material.
What are the physical properties of 3-amino-4-chlorotrifluoromethylbenzene?
3-Hydroxy-4-methoxytrityl (3-Hydroxy-4-methoxytrityl), this physical property is particularly important, and it is related to many chemical and biological applications.
It is a white to off-white crystalline powder, which is a characterization of appearance. The melting point is very critical, about a specific temperature range, this value is crucial for identification and purification. According to its melting point characteristics, it can accurately identify the substance, and it is also an important indicator for controlling the purification process.
In terms of solubility, it has good solubility in common organic solvents such as dichloromethane and chloroform. This property makes it easy to dissolve in the reaction system of organic synthesis and participate in various chemical reactions. However, the solubility in water is very small, and this difference can be effectively separated by the different solubility of the aqueous phase and the organic phase during the separation and purification process.
Stability cannot be ignored. Under normal environmental conditions, it is quite stable and can be stored for a long time without significant deterioration. However, in the environment of strong acids and bases, its structure is easily damaged, because acid and base can react with hydroxyl groups, methoxy groups and other functional groups, thereby changing the molecular structure. Light also affects its stability. Long-term strong light irradiation may cause it to undergo photochemical reactions, which affects its chemical properties.
In addition, it has a certain lipid solubility, which has potential applications in the field of drug development and delivery. With its lipid solubility, it is easier to pass through biofilms to achieve effective drug delivery.
From this perspective, the physical properties of 3-hydroxy-4-methoxytriphenyl methyl are of great significance in chemical synthesis, drug development and many other fields. Only by deeply understanding its physical properties can we make good use of it and promote the development of related fields.
What are the chemical properties of 3-amino-4-chlorotrifluoromethylbenzene?
The chemical properties of 3-hydroxy-4-methoxytriphenyl methyl are as follows:
This substance has certain stability. Because it contains hydroxyl groups, it can exhibit some typical properties of alcohols. The oxygen atom in the hydroxyl group has a lone pair of electrons, which is alkaline and can react with acids. For example, when interacting with strong acids, hydroxyl hydrogen can be protonated to form corresponding salts. At the same time, the hydroxyl group can participate in the esterification reaction. Under suitable catalyst and reaction conditions, it reacts with carboxylic acids or their derivatives to form ester bonds. In this process, the hydrogen atom of the hydroxyl group binds with the hydroxyl group of the carboxylic acid to form water, and the rest is connected to form an ester. The methoxy group of
, because the oxygen atom is directly connected to the benzene ring, has a donating electron conjugation effect, which will affect the electron cloud density distribution of the benzene ring, making the adjacent and para-site electron cloud densities of the benzene ring relatively increase, and enhancing the activity of the electrophilic substitution reaction of the benzene ring. For example, in electrophilic substitution reactions such as halogenation, nitrification, and sulfonation, the methoxy group makes the reaction easier to occur in the adjacent and para-sites.
The triphenyl structure endows the substance with a certain steric barrier. The large triphenyl structure will prevent other molecules from reacting with it, especially in some reactions that require close contact between molecules, the steric barrier effect is significant. This property can sometimes be used to selectively protect specific functional groups, so that the reaction selectively occurs in
In addition, the substance has a certain conjugate system due to multiple benzene ring structures, and has characteristic absorption in the ultraviolet-visible region, which can be used for qualitative and quantitative analysis. Its chemical properties are of great significance in the fields of organic synthesis and medicinal chemistry. For example, it can be used as a protective group to protect hydroxyl groups. After a specific reaction is completed, the protective group can be removed by a suitable method to achieve the synthesis of the target product.
What is the production method of 3-amino-4-chlorotrifluoromethylbenzene?
To prepare 3-amino-4-chlorotrifluorotoluene, the following method can be followed.
First take an appropriate starting material, such as aromatic hydrocarbons containing specific substituents. After the halogenation step, select a suitable halogenating agent, such as chlorine gas, under suitable reaction conditions, halogenate aromatic hydrocarbons, and introduce chlorine atoms at specific positions. This reaction requires attention to the reaction temperature, pressure and the use of catalysts to achieve precise positioning of substitution to obtain chlorine-substituted aromatic hydrocarbon derivatives.
Then, nitrate the derivative. Select a suitable nitrifying agent, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid. Strictly control the reaction conditions, because the nitrification reaction is dangerous and requires precise control of the substitution position. After nitrification, nitro groups can be introduced into the aromatic hydrocarbon ring to obtain compounds containing chlorine and nitro groups.
Then, the reduction reaction is carried out. The nitro group is reduced to an amino group. In this step, a suitable reducing agent, such as iron and hydrochloric acid system, or a catalytic hydrogenation method can be selected. If catalytic hydrogenation is used, a suitable catalyst, such as palladium carbon, needs to be selected to react at a certain temperature and pressure to smoothly convert the nitro group into an amino group.
Then for the product containing chlorine and amino groups, the trifluoromethylation reaction is carried out. Suitable trifluoromethylation reagents can be selected, such as some active reagents containing trifluoromethyl. Under specific reaction conditions and catalysts, trifluoromethyl is introduced into the molecule to obtain 3-amino-4-chlorotrifluorotoluene.
During the whole process, each step of the reaction requires fine regulation of the reaction conditions, and the purity of the raw material, reaction temperature, time, pressure, catalyst and other factors must be properly controlled to improve the yield and purity of the product and obtain the target product.
What should be paid attention to when storing and transporting 3-amino-4-chlorotrifluoromethylbenzene?
3-Amino-4-chlorotrifluorotoluene, when storing and transporting, must pay attention to many key things.
The first priority is safety. This substance may be dangerous. The storage place must be well ventilated, cool and dry, and should be away from fire and heat sources to prevent the risk of fire and explosion. When transporting, it is also necessary to strictly follow relevant safety regulations to ensure that the means of transportation are in good condition and equipped with necessary protective and emergency equipment.
The second is packaging. The packaging must be tight and reliable to prevent leakage. The packaging material should be compatible with the substance and should not react chemically with it. On the storage place and the means of transportation, the name, nature, danger warning and other information should be clearly marked for easy identification and disposal.
The other is isolation. Do not mix or mix with oxidizing substances, alkaline substances, etc. Due to its active chemical nature, contact with certain substances can easily cause violent reactions and endanger safety.
In addition, personnel protection should not be ignored. Those involved in storage and transportation should be equipped with appropriate protective equipment, such as protective gloves, goggles, gas masks, etc., to avoid direct contact with the substance and prevent harm to the body.
And an emergency plan is required. Whether it is storage or transportation, a sound emergency plan should be developed in advance. In the event of an unexpected situation such as leakage, it can respond quickly and effectively to reduce losses and hazards. Such as timely evacuation of personnel, sealing off the site, and taking appropriate plugging and cleaning measures. In this way, the safety of 3-amino-4-chlorotrifluorotoluene during storage and transportation must be ensured.