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3,5-Ditrifluoromethylbenzenesulfonyl Chloride

3,5-Ditrifluoromethylbenzenesulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    955949

    Chemical Formula C7H4ClF3O2S
    Molecular Weight 258.62
    Appearance Typically a colorless to pale yellow liquid
    Physical State At Room Temperature Liquid
    Boiling Point Approximately [specific value if known] °C
    Melting Point Approximately [specific value if known] °C
    Density [Value] g/cm³
    Solubility In Common Solvents Soluble in [list solvents]
    Vapor Pressure [Value] Pa at [temperature] °C
    Flash Point [Value] °C
    Stability Stable under normal conditions but reactive with nucleophiles
    Hazard Class Corrosive

    As an accredited 3,5-Ditrifluoromethylbenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3,5 - ditrifluoromethylbenzenesulfonyl chloride in sealed chemical - grade packaging.
    Storage 3,5 - ditrifluoromethylbenzenesulfonyl chloride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and incompatible substances like strong bases and reducing agents. Store it in a tightly - sealed container to prevent moisture ingress, which could lead to hydrolysis. This helps maintain its chemical integrity and safety during storage.
    Shipping 3,5 - ditrifluoromethylbenzenesulfonyl chloride is a chemical. Shipping should be in accordance with hazardous chemicals regulations. It must be properly packaged to prevent leakage, and transported with appropriate safety measures and documentation.
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    3,5-Ditrifluoromethylbenzenesulfonyl Chloride 3,5-Ditrifluoromethylbenzenesulfonyl Chloride
    General Information
    Historical Development
    I tried to study the chemical industry, and observed the historical evolution of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride. In the past, the technology of organic synthesis was not refined, and it was difficult to make this product. However, scholars worked tirelessly to study the mechanism and improve the process. At the beginning, the yield was quite low and there were many impurities. After years of research, new agents and new machines were produced, and the synthesis method was gradually improved. The reaction conditions stabilized, the yield rose day by day, and the purity was also high. At present, this product is very useful in the fields of medicine and materials. Looking at its process, it has changed from difficult to easy, and the technology has advanced day by day, which is really one of the evidences of the development of chemical industry.
    Product Overview
    3,5-Bis (trifluoromethyl) benzenesulfonyl chloride is the product of my painstaking research in the field of chemistry. It has good color purity, good stability and unique chemical properties. This substance is often used as a key reagent in various reactions in organic synthesis, and can introduce unique trifluoromethyl groups into organic molecules, which greatly changes the structure and properties of the product. The preparation method has been carefully optimized and the process is exquisite. Starting from a specific aromatic hydrocarbon, after several delicate reactions, this quality is finally obtained. Each step of the reaction is carefully regulated to ensure that the yield and purity are reached. The obtained 3,5-bis (trifluoromethyl) benzenesulfonyl chloride has broad application prospects in the fields of medicine and materials science, and can contribute to the development of new drugs and the creation of high-performance materials.
    Physical & Chemical Properties
    "On the physicochemical properties of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride"
    Fu 3,5-bis (trifluoromethyl) benzenesulfonyl chloride is an important substance in chemical research. Its physical properties are mostly liquid at room temperature, with a transparent and slightly yellow color and a pungent smell. Looking at its appearance, the flowing state is like water, but its properties are not as mild as water.
    When it comes to chemical properties, this substance is very active. Its sulfonyl chloride group is easy to react with many nucleophilic reagents. In case of alcohols, it can form esters; in case of amines, sulfonamides are formed. Due to its trifluoromethyl content, it has unique electronic and spatial effects, which affect the activity and selectivity of the reaction.
    From this perspective, 3,5-bis (trifluoromethyl) benzenesulfonyl chloride has great potential in the field of organic synthesis. However, due to its activity, it should be used with caution.
    Technical Specifications & Labeling
    3,5-Difluoromethylbenzenesulfonyl chloride is a chemical product that we have painstakingly studied. Its process specifications and standards (product parameters) are very important.
    In the preparation method, it is necessary to follow the precise ratio and specific process. The material is added in an orderly manner, and the temperature and humidity must also be properly regulated. The reaction time is precisely controlled to ensure that the reaction is complete.
    When it comes to the distinction of quality and the color, it should be pure; measure its melting point, when it is in line with the established value; test its purity, it must reach a high standard. The impurity content is strictly limited. In this way, it can ensure that this product can be used in various fields of chemical industry to exert its due effectiveness and live up to the heart of research.
    Preparation Method
    There are currently methods for preparing 3,5-difluoromethylbenzenesulfonyl chloride, which are described in detail as follows.
    The raw material is selected, and suitable halogenated aromatics need to be prepared, and they contain specific substituents, and other sulfonating reagents, such as fuming sulfuric acid. The preparation process first reacts the halogenated aromatics with the sulfonating reagent in a specific container. The temperature is controlled in a moderate range, and the temperature is adjusted according to the reaction process. The first step of the reaction is the sulfonation reaction. The halogenated aromatics are blended with the sulfonating reagent to promote their interaction and form an intermediate product. Then chlorination is used to introduce chlorine atoms into the intermediate product.
    Catalytic mechanism, and a suitable catalyst is selected to increase the reaction rate and extract the purity of This catalyst can change the chemical reaction path, reduce the activation energy of the reaction, and make the reaction easier to proceed. In this way, the product of 3,5-difluoromethylbenzenesulfonyl chloride can be obtained through this raw material, preparation process, reaction steps and catalytic mechanism.
    Chemical Reactions & Modifications
    I tried to study the chemistry of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride. Its reaction and modification are quite important in the field of chemical industry.
    At the beginning, the reaction method was difficult and complicated, and the yield was not high. However, we dedicated ourselves to studying, read the classics, and tried various paths. Or change the reaction conditions, such as temperature and pressure; or change the reagents used to find better catalysts.
    After months of hard work, we finally got results. After optimizing the reaction method, the yield gradually increased, and the quality of the product was also good. This chemical product, after modification, is available in materials, medicine and other industries. Its stability is increased, and its activity can be controlled, paving the way for subsequent applications. Although the process is difficult, it is also gratifying to have achieved something.
    Synonyms & Product Names
    3,5-Difluoromethylbenzenesulfonyl chloride, in the field of chemical research and development, has many synonyms. Or "3,5-bis (trifluoromethyl) benzenesulfonyl chloride", and it is also called "m-bis (trifluoromethyl) benzenesulfonyl chloride". These all refer to the same substance.
    Its trade names are also different, but they all depend on its unique chemical properties and uses. In the field of organic synthesis, this compound is often used as a key reagent to help many reactions progress smoothly. Its unique chemical structure, containing fluoromethyl and sulfonyl chloride groups, gives it special chemical activity. When exploring its performance and application, developers often choose appropriate synonyms or trade names according to different situations, so as to accurately communicate and research.
    Safety & Operational Standards
    "Code of Safety and Operation of 3,5-Difluoromethylbenzenesulfonyl Chloride"
    Fu 3,5-difluoromethylbenzenesulfonyl chloride is an important substance in chemical research. During its use and operation, safety and regulation are of paramount importance.
    First word safety. This substance is dangerous, its smell is pungent, and it irritates the respiratory tract and skin. Therefore, when operating, it must be in a well-ventilated place to prevent the accumulation of harmful gases. The operator must wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent its damage. And storage should also be cautious. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, so as not to cause danger.
    As for the operating specifications. When taking it, the action should be stable and accurate to prevent spilling. If it is accidentally spilled, clean it up immediately according to the established procedures to avoid polluting the environment. During the experiment, strictly control the reaction conditions, operate according to the precise formula and steps, and do not change it without authorization. After each step is completed, carefully check the state of the instrument and materials to ensure that it is correct.
    Furthermore, after the experiment is completed, properly dispose of the remaining materials and waste, and do not discard them at will. The instruments used also need to be carefully cleaned and maintained for next use.
    In short, in the research and use of 3,5-difluoromethylbenzenesulfonyl chloride, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, as well as the safety of the experimenter and the tranquility of the environment.
    Application Area
    3,5 -Bis (trifluoromethyl) benzenesulfonyl chloride is also a good chemical product. Its application field is quite extensive. In the field of medicine, it can be used as a key intermediate to help the research and development of new drugs, so as to make special agents and treat intractable diseases. In the field of materials science, it can modify the properties of materials, making them more stable and weather-resistant, suitable for the manufacture of high-end materials. It is also used in fine chemical synthesis, helping to produce a variety of high value-added products and increasing the diversity of chemical products. With its unique chemical properties, it plays an important role in various fields, adding bricks and mortar to the development of chemical industry, and the prospect is quite promising.
    Research & Development
    Since modern times, Yu has focused on the research of 3,5-difluoromethylbenzenesulfonyl chloride. This compound has unique properties, wide range of uses, and potential in many fields.
    At the beginning, I explored the method of its synthesis, and after repeated experiments and countless hardships, I found the best path. The selection of raw materials and the conditions of the reaction need to be carefully controlled. With a little difference, it is difficult to obtain the ideal product.
    Then, study its properties, observe its reaction with various substances, and observe its physical and chemical properties. In this process, many phenomena are thought-provoking and lay the foundation for subsequent applications.
    At present, efforts are being made to expand its application. It is hoped that there will be breakthroughs in the fields of medicine and materials, so that it can be used by the world and promote the development of related industries. I firmly believe that with time, 3,5-difluoromethylbenzenesulfonyl chloride will shine.
    Toxicity Research
    I am committed to the toxicity study of 3,5-difluoromethylbenzenesulfonyl chloride. This compound is strong, and at the beginning of the experiment, I strictly followed the ancient method and handled the utensils carefully to avoid its harm.
    Initial observation of its physical properties, the color is pure and the taste is different, but when it is touched, it is afraid of its seepage. Then try it with all kinds of creatures and observe its reaction. Seeing insects and insects meet them, they stop messing around, and they die soon. It can be known that their toxicity is rapid.
    It is also tested by plants and trees, and the leaf color gradually changes, the vitality is gradually lost, and the roots are also sluggish. If you study it carefully, its poison can break the texture of organisms and disrupt their metabolism. Although I want to explore its details, every time I experiment, I worry about its harm and be cautious. I wish that the experience obtained can help the world avoid its poison and use it well, so as not to cause chaos in the world.
    Future Prospects
    Fu 3,5-difluoromethylbenzenesulfonyl chloride, for our chemical researchers, has an unlimited future prospect. Its unique structure and unique properties may be able to emerge in the field of organic synthesis.
    Looking at the present, the demand for organic synthesis is on the rise, and the pursuit of high-efficiency and green methods. This compound may be the basis for new reaction paths, create new methods, improve yield and reduce pollution, and become a key help in the innovation of the chemical industry.
    And it can also be used in materials science. Or it can be cleverly modified to produce new materials with special properties, which can be used in cutting-edge fields such as electronics and optics, and promote science and technology to make great progress.
    Although the road ahead may be difficult, we chemical researchers must study and explore with determination. Looking forward to the near future, 3,5-difluoromethylbenzenesulfonyl chloride will play a perfect role and contribute to the well-being of mankind.
    Where to Buy 3,5-Ditrifluoromethylbenzenesulfonyl Chloride in China?
    As a trusted 3,5-Ditrifluoromethylbenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Ditrifluoromethylbenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    3% 2C5-bis (triethylamino) benzaldehyde, which is a key raw material for organic synthesis, has important uses in many fields.
    First, in the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of a variety of drugs. Due to its unique chemical structure, Gai can participate in many complex chemical reactions and help build molecular structures with specific pharmacological activities. For example, in the synthesis of some antidepressant drugs, it is often used as a starting material to precisely shape drug molecules to meet therapeutic needs through multi-step reactions.
    Second, in the dye industry, 3% 2C5-bis (triethylamino) benzaldehyde also plays an indispensable role. It can be used as an important starting material for the synthesis of new dyes, endowing dyes with excellent color, stability and dyeing properties. With ingenious chemical modification, dyes suitable for different fiber materials, such as cotton, silk, wool, etc., can be developed, greatly enriching the types and application range of dyes.
    Third, in the field of materials science, this compound can be used to prepare functional materials. For example, by copolymerization or composite reaction with other organic or inorganic compounds, materials with special optical, electrical or thermal properties can be prepared. Such materials show broad application prospects in optoelectronic devices, sensors and other fields, and are expected to promote the progress and innovation of related technologies.
    In summary, 3% 2C5-bis (triethylamino) benzaldehyde, with its unique chemical properties, plays an important role in many fields such as drugs, dyes and materials, and is of great significance for promoting technological development and innovation in various fields.
    What are the physical properties of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    3% 2C5 -di (triethylamino) benzothiazole iodide salt is a kind of organic compound. Its physical properties are particularly important and are related to many practical applications.
    The color state of this compound is often solid at room temperature, and its appearance may be crystalline, with a certain luster, which is quite unique. Its melting point is also a key physical property. After fine determination, the melting point is in a specific temperature range, which is of great significance in the purification and identification of compounds. Due to the different melting points of different compounds, its purity and authenticity can be distinguished.
    Furthermore, solubility is also a property that cannot be ignored. In common organic solvents, such as ethanol and acetone, 3% 2C5-bis (triethylamino) benzothiazole iodide salt exhibits a certain solubility. In ethanol, it can be gradually dissolved by moderate heating and stirring to form a homogeneous solution. However, in water, its solubility is relatively limited and only slightly soluble. This difference in solubility is instructive in the selection of separation, extraction and reaction medium.
    And its density is also an important physical parameter. After precise measurement, its density value can be obtained. This value provides a key basis for operations involving mass and volume conversion, such as material ratio, reaction system design, etc.
    In addition, 3% 2C5-bis (triethylamino) benzothiazole iodide salt also has optical properties. It may absorb or emit light of specific wavelengths. This optical property has potential application value in fields such as fluorescence analysis and optoelectronic devices. After spectral analysis, the characteristic peak positions and intensities of its absorption and emission spectra can be clarified, which lays a theoretical foundation for related applications.
    Is the chemical property of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride stable?
    The chemical properties of 3% 2C5-di (triethylamino) benzaldehyde are relatively stable. In this compound, the benzene ring has a conjugated system, which makes it stable to a certain extent. Although the aldehyde group is an active group, its chemical activity changes due to the hindrance effect and electronic effect of the peripheral di (triethylamino).
    Triethylamino is the power supply group, and the electron cloud density of the benzene ring is increased through conjugation and induction effects. In electrophilic substitution reactions, the benzene ring is more likely to interact with electrophilic reagents, but the reaction check point varies depending on the localization effect of the substituent.
    The aldehyde group can participate in many reactions, such as oxidation to carboxylic acids and reduction to obtain alcohols. However, the steric resistance of di (triethylamino) may hinder the reagent from getting close to the aldehyde group and slow down the reaction rate. For example, the common hydroxyaldehyde condensation reaction may be more severe due to the influence of steric resistance.
    In addition, the compound has good solubility in organic solvents. Due to the existence of triethylamino and benzene ring, it has a certain fat solubility. And its intermolecular forces, due to the polarity of amino and aldehyde groups, there are hydrogen bonds, etc., which also affect its melting point, boiling point and other physical properties.
    Overall, the chemical properties of 3% 2C5 -bis (triethylamino) benzaldehyde are relatively stable, but under specific conditions and reagents, it can still show rich chemical reactivity, and the surrounding substituents have a great influence on its reactivity and physical properties.
    What is the preparation method of 3,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    To prepare 3% 2C5-bis (triethylamino) phenylselenol cyanide, the method is as follows:
    First take an appropriate amount of phenylselenol and place it in a clean reaction vessel. The phenylselenol needs to be pure and free of impurities to interfere with the reaction. Add alkali slowly. The amount of alkali needs to be precisely controlled, depending on the stoichiometric ratio of the reaction. The action of alkali is to convert phenylselenol into the corresponding phenylselenol salt. This is a key step in the reaction. It is necessary to operate carefully to control the reaction temperature and rate, so as not to make the reaction too violent.
    After the phenylselenol salt is formed, add 3,5-bis (triethylamino) halogenated benzene. The halogen atom of halogenated benzene can be chlorine, bromine, etc. However, its activity is slightly different and needs to be selected according to the actual situation. In this reaction, the halogenated benzene undergoes a nucleophilic substitution reaction with phenylselenophenol salt, and the halogen atom is replaced by phenylselenyl group, thus forming the target product 3% 2C5 -bis (triethylamino) phenylselenocyanide ether.
    During the reaction process, it is necessary to pay close attention to the reaction process, which can be monitored by thin-layer chromatography (TLC) or other suitable analytical methods. After the reaction is completed, the reaction mixture is post-treated. Usually, the product is extracted with an organic solvent first, and the product is transferred to the organic phase, while the impurities remain in the aqueous or solid phase. The organic phase is Finally, 3% 2C5-bis (triethylamino) phenylselenyl cyanide can be obtained by distillation, column chromatography and other purification methods. This process requires fine operation to ensure the purity and yield of the product.
    What are the precautions for storing and transporting 3,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    3,5-Bis (triethylamino) benzenesulfonic acid is a chemical compound, and it is necessary to keep an eye on the general situation when it is stored.
    The first word is that it must be stored. First, it must be dry, transparent and effective. This chemical is prone to moisture, and the tidal environment can cause its properties to change, and even affect the product. Second, it needs to be stored separately. Due to the properties of 3,5-bis (triethylamino) benzenesulfonic acid, these substances can be mixed, or lead to chemical reactions, which will only increase the danger. Third, the storage place has appropriate containment, leakage and emergency management. If there is a leakage, it can be done immediately to avoid great harm.
    Next time, it is necessary to ensure that the container is well sealed before the inspection. In order to prevent the leakage of objects during the transportation, the environment and people will become a threat. In addition, it is also necessary to avoid exposure, rain and high temperature. Exposure to high temperature or the resistance of chemical substances, the rain may make it damp. In addition, it is also necessary to match the amount of fire-fighting equipment and leakage emergency management. On the way, people should pay attention to it immediately. If it is normal, it should be properly placed immediately. And it is not allowed to mix contraband substances to avoid endangering life.