3,5-Difluorobenzeneboronic Acid

Hongda Chemical

Specifications

HS Code	943710
Chemical Formula	C6H5BF2O2
Molar Mass	156.91 g/mol
Appearance	White to off - white solid
Melting Point	142 - 146 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, tetrahydrofuran
Purity	Typically high - purity (e.g., 95%+)
Acidity	Weakly acidic due to the boronic acid group
Stability	Stable under normal conditions, but sensitive to strong oxidizing agents
Odor	Odorless or very faint odor

As an accredited 3,5-Difluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 3,5 - difluorobenzeneboronic acid packaged in a sealed plastic bottle.
Storage	3,5 - difluorobenzeneboronic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and moisture as it may react or degrade. Store in a tightly sealed container to prevent contact with air and humidity. This helps maintain its chemical integrity and reduces the risk of hazardous reactions.
Shipping	3,5 - difluorobenzeneboronic acid is shipped in well - sealed containers, compliant with chemical transportation regulations. It's carefully packaged to prevent leakage, with proper labeling indicating its chemical nature for safe and proper handling during transit.

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General Information

Historical Development

3,5-Difluorophenylboronic acid is also an important agent in organic synthesis. At the beginning, chemists studied and searched for it, but the preparation was difficult at first, and the yield was quite low. However, many wise men worked tirelessly, and after several years of research, they improved the production method. First, it was obtained by a cumbersome method, although it was impure and small in quantity. After repeated tests, optimization steps, and selection of good materials, the yield rose and the purity was also good. Today, it is widely used in the fields of medicine and materials. In the past, the road of synthesis was like a thorn road. Chemists moved forward fearlessly, and finally obtained this useful product. It blossomed in the field of chemistry and became an indispensable thing in organic synthesis. It also laid the foundation for future research. Wait for more strange uses to be explored by the world.

Product Overview

3,5-Difluorophenylboronic acid is also a key reagent for organic synthesis. Its shape is like a white crystalline powder, with high chemical purity. This product has important uses in many fields, such as medicinal chemistry, material science, etc. In drug research and development, it can be used as a key intermediate to help build complex molecular structures to find new drugs with high efficiency and low toxicity. In the field of materials, it can participate in the synthesis and modification of materials to improve the special properties of materials. Its preparation process has been optimized many times, and it has now reached a stable and efficient state. From the starting material, through multi-step reaction, the reaction conditions, such as temperature and catalyst, are finely adjusted to obtain high-purity products. And through rigorous quality inspection to ensure high quality, it can meet the stringent needs of various fields and play an important role in scientific research and industrial production.

Physical & Chemical Properties

3,5-Difluorophenylboronic acid, a substance with unique physical and chemical properties. Its shape or white crystalline powder is stable at room temperature and pressure. Looking at its melting point, about a certain value, this is its important physical characteristic, which can be used to determine its purity. In terms of solubility, it is soluble in some organic solvents, and its solubility in water is also specific, which is related to its dispersion and reaction in different media. Chemical properties are active, boron atoms are highly active, and can often participate in a variety of organic reactions, such as coupling reactions, and halogenated hydrocarbons to form carbon-carbon bonds or carbon-hetero bonds. It is widely used in the field of organic synthesis and is a key raw material for the preparation of complex organic compounds. With its characteristics, it can expand the path of organic synthesis and create a variety of organic products.

Technical Specifications & Labeling

3,5-Difluorophenylboronic acid is a chemical product I have recently developed. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis of this product requires a delicate method. The starting materials must be selected, and the reaction conditions should be precisely controlled. Temperature, pressure, and reaction time are all key. In a specific reactor, the raw materials are reacted in sequence and purified through multiple processes to obtain high-purity 3,5-difluorophenylboronic acid.
As for the identification (product parameters), its appearance should be white crystalline powder, the purity should be above 99%, and the melting point should be within a specific range. This is an important indicator for judging product quality. And the packaging label should also be clear, indicating the product name, specifications, production date, etc., so as to ensure that the product quality and application are correct.

Preparation Method

The method of making 3,5-difluorophenylboronic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. First, an appropriate amount of fluorobenzene is taken, and it is mixed with a boronizing reagent in a specific ratio. This boronizing reagent needs to be carefully selected, which is related to the reaction effect. In a special reactor, the temperature is controlled to a certain precise range. If the temperature is too high or too low, it will affect the purity and yield of the product. At the beginning of the reaction, the stirring rate is also critical, and it needs to be uniform and stable to fully blend the materials. When the reaction is carried out to a certain stage, a specific catalyst is added. This catalyst can change the chemical reaction rate and optimize the reaction path. The amount of catalyst and the timing of addition are all exquisite, and the appropriate amount can be After the multi-step reaction, the product needs to be finely purified to remove impurities and improve purity, and finally obtain high-quality 3,5-difluorophenylboronic acid. The whole process, all links are closely linked, and any error will cause the product to fail to meet expectations.

Chemical Reactions & Modifications

I am committed to the research of chemical products, and recently focused on the research of 3,5-Difluorobenzeneboronic Acid. Its chemical reaction is very difficult to think about.
The reaction of this compound is often subject to many factors. The method of the past may encounter a slow reaction and an unsatisfactory yield. Because the reaction conditions are difficult to control, the activity of the reactants can also be investigated.
I have dedicated myself to studying, hoping for a method of modification. Thinking of changing the reaction medium or introducing a specific catalyst, hoping to promote the rate of the reaction and improve the purity of the product. Also consider the ratio of the reactants, fine debugging, hoping to get the best chemical change. It is expected that the chemical reaction and performance improvement of 3,5-Difluorobenzeneboronic Acid will make achievements and contribute to the research of chemical products.

Synonyms & Product Names

In the chemical industry, new products have emerged one after another. Today, there is a product called 3,5-difluorophenylboronic acid (3,5-Difluorobenzeneboronic Acid). This product is used in various fields of chemical industry and has a wide range of uses. Its aliases also exist, but they all refer to the same good product.
In the Guanfu market, all kinds of product names are different, but their essence is studied, or they are the same thing. 3,5-difluorophenylboronic acid, with its unique properties, helps extraordinary things in synthesis reactions and other things. Or there are other names, all due to differences in industry habits and regions, but they are all the same treasure we have studied.
As chemical researchers, we understand the various names of this thing. Although the names are different, they are the same. Only by exploring the road and accurately recognizing it can we obtain its true meaning, so as to promote the progress of chemical industry and seek the prosperity of the industry.

Safety & Operational Standards

"Specifications for safety and operation of 3,5-difluorophenylboronic acid"
If 3,5-difluorophenylboronic acid is used in chemical research, it is also a commonly used product. If you want to make good use of this product, you must first clarify its safety and operation specifications, so that the experiment can be smooth and the safety of people and the environment can be ensured.
First word safety. This product has a certain chemical activity. When storing, it should be placed in a cool, dry and well-ventilated place, away from water and fire, and away from heat sources. If it encounters water or has adverse reactions, it is essential to be waterproof. When taking it, use appropriate protective equipment, such as gloves and goggles, to prevent it from touching the skin and entering the eyes. If you accidentally touch it, quickly rinse it with a lot of water, and seek medical attention for those who are serious.
Second-class operation. In the experimental operation room, the equipment must be clean and dry. When weighing, the method should be stable and accurate, according to the amount required by the experiment, not more or less. During the reaction process, pay close attention to temperature, time and other conditions, because it may have a huge impact on the result of the reaction. After the reaction, properly dispose of the remaining materials. Do not dispose of them at will. According to relevant regulations, classify them to prevent environmental pollution.
In short, the experiment of operating 3,5-difluorophenylboronic acid must be based on safety and guided by norms, so that the purpose of scientific research can be achieved without fear.

Application Area

3,5-Difluorophenylboronic acid is also a good solution. Its application domain is wide. In the field of synthesis, it is often used for the production of carbon-boron. The formation of this process can lead to the development of many specific compounds, laying the foundation for new research and materials science.
In the new research, it can build the core skeleton of the molecule. By ingeniously inverse methods, it can be introduced into the target molecule, which can precisely control the activity, solubility and other properties of the substance, and improve the performance of the substance.
In the field of materials science, 3,5-difluorophenylboronic acid can be used in functional materials. For example, in the light material, it can be used to change the properties of the material, improve the properties of the material, and improve the properties of the material, etc., to give the material new functions, so as to meet the needs of different fields. Moreover, it has exhibited important value in many application fields.

Research & Development

Today there is a substance called 3,5 - difluorophenylboronic acid (3,5 - Difluorobenzeneboronic Acid). We study this substance with the heart of scientific research. At first, explore its properties, understand its physical and chemical characteristics, and lay the foundation for subsequent investigation.
Then, study the method of its preparation. After repeated experiments, observe the influence of different conditions on its synthesis. Adjust the temperature or change the proportion of reagents to ensure that the yield is good. Examine its reaction mechanism and clarify the reasons for each step change.
As for the application, there are also studies. In the field of organic synthesis, observe its effect as a coupling agent, observe its reaction with other substances, form new compounds, and expand the way of organic synthesis.
We are committed to the research and development of this object, hoping to make it shine in various fields and contribute to the progress of science.

Toxicity Research

Recently, I have been studying 3,5 - Difluorobenzeneboronic Acid. I have focused on its toxicity research, knowing that this is related to many aspects.
Detailed investigation of its properties, this compound has a unique structure, but it may contain potential toxicity. In order to investigate the fact, I have used a variety of ancient methods to explore, observe its response to other things, and observe its changes in different environments.
After repeated investigation, it was found that it has the ability to cause harm to some small organisms under specific conditions. Although the exact effect on the human body is not fully understood, it is inferred from circumstantial evidence that it is inevitable.
I shall continue to study, analyze the root cause of its toxicity with the rigor of the ancient law, and hope to obtain detailed results, so as to avoid harm and profit for everyone when using this product, protect everyone's health, and leave some reference for those who study this product in the future.

Future Prospects

Today, there is a thing called 3,5-difluorophenylboronic acid, which can be seen in the future of our chemical research. The properties of this thing can be used in various organic synthesis paths, which can pave the way for the creation of new things and the development of new territories.
We look to the future, or in the field of medicinal chemistry, we can use its power to make special medicines and heal all kinds of diseases. Or in the field of material science, we can use its quality to make novel materials and apply them to high-tech places. Although the road ahead is long, with our enthusiasm for research and the courage to explore, we will surely be able to unearth its hidden power.
In the coming days, 3,5-difluorophenylboronic acid will surely shine, establishing an unshakable foundation in the chemical forest, contributing to human well-being, achieving extraordinary achievements, and developing infinite possibilities.

Where to Buy 3,5-Difluorobenzeneboronic Acid in China?

As a trusted 3,5-Difluorobenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3,5-Difluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,5-difluorophenylboronic acid?

3,5-Dihydroxybenzoic acid, also known as gentian acid, has a wide range of main uses.
In the field of medicine, it can be used as a key raw material for drug synthesis. Many drugs with anti-inflammatory and antioxidant effects need to build specific chemical structures on this basis during the synthesis process. For example, some new drugs used to relieve inflammation, 3,5-dihydroxybenzoic acid has a phenolic hydroxyl structure that can participate in many chemical reactions and help synthesize compounds with specific pharmacological activities to achieve the regulation of inflammatory factors, thereby reducing the body's inflammatory state.
In the cosmetic industry, with its antioxidant properties, 3,5-dihydroxybenzoic acid can be added to skin care products. It can neutralize the free radicals generated in the skin and delay the aging process of the skin. Free radicals are one of the key factors that cause skin aging. This substance can effectively scavenge free radicals, maintain the normal physiological function of skin cells, keep the skin elastic and shiny, and prevent wrinkles, sagging and other aging phenomena.
In the chemical industry, it can act as an intermediate in organic synthesis. It can participate in the preparation of polymer materials with special functions, and by means of its polymerization reaction with other monomers, it can endow polymer materials with specific chemical and physical properties, such as improving the stability and solubility of materials, so as to expand the application range of materials in different fields, such as in the research and development of coatings, adhesives and other products.
To sum up, 3,5-dihydroxybenzoic acid plays an indispensable role in many fields such as medicine, cosmetics, and chemicals, and is of great significance to promoting the development of related industries.

What are the physical properties of 3,5-difluorophenylboronic acid?

3% 2C5 -diethylbenzoic acid is an organic compound with the following physical properties:
1. ** Appearance and Properties **: At room temperature, this substance is often in the state of white to light yellow crystalline powder, with a fine texture and a certain luster. Just like fine snow powder, it flickers slightly under light.
2. ** Melting Boiling Point **: The melting point is about 64-67 ° C. When the temperature gradually rises, it will be like solid ice in the warm sun, slowly melting from solid to liquid; the boiling point is about 285-287 ° C. If the temperature continues to rise to the boiling point, it will turn into a gaseous state and rise in the air.
3. ** Solubility **: It has good solubility in organic solvents, such as ethanol, ether, chloroform, etc., which can be melted with it, just like fish water; however, it has little solubility in water, just like oil and water are difficult to melt, because the molecular structure of the compound is hydrophobic.
4. ** Density **: The density is about 1.045g/cm ³, which is slightly heavier than common water. If it is placed in water, it will sink to the bottom like a stone, slowly sinking.
5. ** Smell **: It has a weak and unique aromatic smell, just like a faint flower fragrance, not pungent, but clearly audible, gently diffusing in the air.

What are the synthesis methods of 3,5-difluorophenylboronic acid?

The method of synthesizing 3,5-dihydroxybenzoic acid has been used through the ages, and all kinds of ingenuity have been used. In the past, the method of organic synthesis was first developed, and everyone explored it endlessly.
First, salicylic acid can be used as the starting material. After acylation, bromination, and then alkaline hydrolysis and acidification, 3,5-dihydroxybenzoic acid is finally obtained. The salicylic acid is first acylated with acetic anhydride, and the phenolic hydroxyl is acetylated to obtain acetylsalicylic acid. This step is intended to protect the phenolic hydroxyl from damage in subsequent reactions. Then, bromine is brominated with bromine, and bromine atoms are introduced into the phenyl ring of acetylsalicylic acid. This reaction needs to be carried out under appropriate solvent and catalytic conditions to make the bromine atoms just fall into the desired position. After the bromination is completed, hydrolysis with alkali is used to leave the acetyl group, and the bromine atoms are hydrolyzed into hydroxyl groups at the same time. This process is strictly controlled by the reaction conditions, and the concentration, temperature and time of the base are all exquisite. Finally, the target product is obtained after acidification treatment.
Second, resorcinol is used as a raw material, and it can also be obtained. Under the action of a catalyst, resorcinol and dimethyl carbonate undergo a phenol transesterification reaction, which can introduce carboxyl groups. The catalyst used in this reaction is quite critical, and different catalysts have a significant impact on the reaction rate and selectivity. After a series of reaction operations, the reaction conditions are skillfully adjusted, so that the carboxyl group is introduced at the 3,5 position of resorcinol, and then the subsequent refining steps remove impurities and purify the product, and 3,5-dihydroxybenzoic acid can also be obtained.
Furthermore, it is also obtained by biotransformation or chemical modification starting with natural products. Some plant extracts or microbial metabolites can be transformed into 3,5-dihydroxybenzoic acid by ingenious modification. Although this approach has the advantages of green and sustainable, it often faces problems such as limited raw material sources and complex transformation processes. It requires fine regulation of biological reactions or chemical modification steps to achieve.
All kinds of synthesis methods have their own advantages and disadvantages. It is necessary to make a careful choice according to actual needs, raw material availability, cost considerations and other factors. Only in the process of organic synthesis can we obtain this 3,5-dihydroxybenzoic acid.

What are the precautions for storing and transporting 3,5-difluorophenylboronic acid?

When storing and transporting 3% 2C5-diethylbenzoic acid, many matters need to be paid attention to.
First of all, its properties are related to the method of storage and transportation. This acid has certain chemical activity and is easy to react with certain substances. Therefore, when storing, it is necessary to choose a suitable container. Take glass material as an example, although its chemical stability is good, it is necessary to pay attention to the special situation such as strong alkali, or the risk of reaction. Metal containers need to be avoided because of the metal ions they contain or the chemical reaction of this acid, which affects the quality.
Temperature and humidity are also key. It should be stored in a cool and dry place away from direct sunlight. If the temperature is too high, it may cause its volatilization to intensify, or even cause a decomposition reaction; if the humidity is too high, it may cause the acid to deteriorate under moisture.
When transporting, safety is the most important thing. The acid may be corrosive to a certain extent, and the packaging must be tight to ensure that there is no risk of leakage during transportation. And the transportation vehicle needs to be equipped with corresponding emergency treatment equipment. If there is an emergency situation such as leakage, it can be responded to in time.
Furthermore, the logo should not be ignored. Whether it is a storage container or a transportation package, it should be clearly marked with the words "3% 2C5-diethylbenzoic acid" and a warning label should be attached to inform everyone that this is a certain dangerous chemical and must be operated according to the regulations.
In addition, when coexisting with other chemicals, they should be strictly classified for storage and transportation, and must not be mixed with strong oxidants, strong alkalis and other substances that are easy to react with to prevent accidents.
Only during storage and transportation can the quality and safety of 3% 2C5-diethylbenzoic acid be guaranteed, and accidents can be avoided.

What is the approximate market price of 3,5-difluorophenylboronic acid?

3,5-Diethoxybenzoic acid, the price between markets is difficult to determine, because it varies depending on quality, supply and demand, time and place. Now it is speculated according to common sense.
It is sold in the market, mostly in the chemical raw material market, and is used in the chemical industry, medicine and other industries. If the quality is ordinary, the quantity is not huge, the price per kilogram, or in the hundreds of gold. If the quality is high, in line with the high purity of medicine, the price should be doubled.
In the transaction of chemical raw materials, the quantity is also related to the price. If you buy in bulk, the merchant will reduce the price slightly in order to promote trade or give a discount; if you buy it sporadically, the price may be slightly higher.
And the supply and demand of the city, especially the price. If there are many people in need and there are few people in supply, the price will rise; if the supply exceeds the demand, the price will be suppressed. It varies from time to time, and the price also varies. In prosperous places, in peak seasons, the price may be high; in remote places, when the demand is low, the price may be low.
is that the market price of 3,5-diethoxybenzoic acid is roughly hundreds of gold per kilogram. If you want to get a definite price, you must carefully consider the quality, quantity, supply and demand in a timely manner.