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3,5-Difluoro-4-Bromonitrobenzene

3,5-Difluoro-4-Bromonitrobenzene

Hongda Chemical

Specifications

HS Code

895290

Chemical Formula C6H2BrF2NO2
Molecular Weight 252.986
Appearance Solid
Melting Point 86 - 88 °C
Boiling Point 230 - 232 °C
Density 1.91 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point 92.9±25.9 °C
Refractive Index 1.553
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 3,5-Difluoro-4-Bromonitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3,5 - difluoro - 4 - bromonitrobenzene packaged in a sealed glass bottle.
Storage 3,5 - difluoro - 4 - bromonitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers and reducing agents. Store it in a tightly sealed container to prevent leakage and exposure to air and moisture, which could potentially cause decomposition or reactivity issues.
Shipping 3,5 - difluoro - 4 - bromonitrobenzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, handling, and transportation to prevent leakage and ensure safety.
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3,5-Difluoro-4-Bromonitrobenzene 3,5-Difluoro-4-Bromonitrobenzene
General Information
Historical Development
3,5-Difluoro-4-bromo-nitrobenzene is also an organic compound. Its initial research really depends on the research of many scholars in chemistry. In the past, scholars first ventured into this field, seeking up and down the road of organic synthesis. At that time, the instruments were not refined, and the techniques were not ready, but they set their sights high and were not afraid of difficulties.
After several years of hard work, the synthesis method gradually matured. At the beginning, the yield was low, and the impurities were numerous. Everyone worked hard to improve the process. Or change the reaction conditions, or try new reagents, repeatedly pushing, unremitting.
To this day, its preparation process has reached a good level, and it is widely used in the fields of medicine and materials. Reviewing its development history, it is a glorious page in the history of chemistry. The achievements of all sages are indelible and serve as a model for future generations to study.
Product Overview
Description of 3,5-difluoro-4-bromo-nitrobenzene
Fu 3,5-difluoro-4-bromo-nitrobenzene is an important product in organic synthesis. Its shape is crystalline, its color is light yellow, and it has a specific degree of melting. In the field of chemistry, it has a wide range of uses and is a key raw material for the preparation of various fine chemicals and pharmaceuticals.
Looking at the structure of its molecules, fluorine, bromine and nitro are ingeniously connected, giving it unique chemical activity. Because of the high electronegativity of fluorine atoms, the polarity of molecules is different, and the reactivity is also unusual. Bromine atoms provide an opportunity for nucleophilic substitution and other reactions. The presence of nitro groups affects the distribution of electron clouds, so that the product plays a variety of roles in organic reactions.
Synthesis method, or through multi-step reactions, according to different paths, select suitable reagents and conditions, and carefully regulate, can be obtained. When preparing, the details of the reaction need to be carefully managed to achieve high-purity products.
In short, 3,5-difluoro-4-bromonitrobenzene has important value in the chemical industry, medicine and other industries, and has made great contributions to promoting the development of chemical synthesis.
Physical & Chemical Properties
3,5-Difluoro-4-bromo-nitrobenzene is an important substance in chemical research. Its physical and chemical properties are unique and related to many reactions and applications.
Looking at its physical properties, under room temperature, it may be a solid, and its color state may have certain characteristics. Its melting point and boiling point are key physical parameters, which can help determine the conditions of purification and separation. In terms of solubility, the dissolution of a specific solvent also affects the choice of reaction medium.
When it comes to chemical properties, because it contains fluorine, bromine, nitro and other functional groups, it is significantly active. Nitro has strong electron absorption, which changes the electron cloud density of the benzene ring and affects the activity of electrophilic substitution. The existence of fluorine and bromine atoms, or the difference in nucleophilic substitution reaction paths. These properties lay the foundation for the synthesis of new compounds, the development of drugs or materials, and are actually elements that cannot be ignored in chemical research.
Technical Specifications & Labeling
3,5-Difluoro-4-bromo-nitrobenzene, this is the chemical I recently studied. Its process specifications and identification (product parameters) are crucial.
Process specifications need to be strictly controlled. The selection of raw materials must be carefully selected, and impurities must not be mixed at all. The reaction conditions also need to be precisely controlled, and the temperature and pressure must be fixed. At a specific temperature, according to a specific ratio of the reactant, the reaction time must also be strictly followed to ensure the purity and yield of the product.
In terms of identification, the product parameters should be clearly marked. Its purity geometry and impurity content must be clear. Appearance properties should also be described in detail, and color and state must be accurate. In this way, it is possible for others to understand the characteristics of the product at a glance when using it, ensuring safety and effectiveness.
Preparation Method
The method of preparing 3,5-difluoro-4-bromo-nitrobenzene is as follows: Prepare the raw materials first, based on fluoride, bromide and nitrobenzene, and measure them in appropriate proportions.
In a clean reactor, control the temperature moderately, first add bromide and nitrobenzene, stir well, and slowly add fluoride. During the reaction, closely observe the changes in temperature and pressure, and adjust them in a timely manner to ensure the stability of the reaction.
After the reaction is completed, it is separated and purified. First, the untreated raw materials are removed by distillation, followed by extraction and crystallization to obtain pure 3,5-difluoro-4-bromo-nitrobenzene.
During the preparation, a strict quality control system is established, and each step is inspected in detail to ensure that the product meets the standards. And prepare emergency cases, respond quickly to emergencies, such as leakage, overheating, etc., to ensure production safety.
Chemical Reactions & Modifications
Nowadays, there are chemical substances called 3,5-difluoro-4-bromo-nitrobenzene. It is important for researchers on the way to chemical reaction.
In the process of chemical reaction, its behavior changes, or it is combined with other substances to produce new quality. However, in order to seek its best effect, it is often necessary to study the conditions of chemical reaction, such as temperature, pressure, catalyst and the like.
At the beginning, this reaction was slow but difficult to advance, because above the benzene ring, fluorine, bromine, and nitro groups each showed their own properties and hindered each other. To change its response, you can try to adjust the genus of the catalyst. The appropriate catalyst can lower the energy barrier of the response and promote its rapid progress.
Or change the temperature and pressure, the temperature and height will be divided into different speeds, and it should be easy to start; if the pressure is appropriate, the rate of collision between points will increase. After many trials and studies, there may be appropriate methods to make this process go smoothly, and the quality and quantity of the product are in good condition. It is of great use in industrial production and academic research.
Synonyms & Product Names
There is a chemical substance called 3,5-difluoro-4-bromo-nitrobenzene. This chemical substance is used in various fields. It also has another name, but they all refer to the same entity.
Throughout the ages, the names of chemical substances have often varied according to regions, habits, and uses. This 3,5-difluoro-4-bromo-nitrobenzene, or by some party, is called by his name, but its essence remains unchanged.
In the course of my chemical research, I know very well that it is not uncommon to have more than one substance. Either because of the order of discovery, or because of the convenience of calling, there are more than one of the same thing. This 3,5-difluoro-4-bromo-nitrobenzene has different names, but its chemical properties and structural characteristics are all consistent. When we study, we should understand its essence and not be confused by many people, so as to achieve in-depth understanding and good use of it.
Safety & Operational Standards
3,5-Difluoro-4-bromo-nitrobenzene is also a chemical substance. Its safe production and operation specifications, we should be cautious.
At the beginning of preparation, all utensils must be clean and dry to prevent impurities from disturbing. The purity and quantity of the medicine used should be accurate, according to the formula ratio, and there should be no slight difference.
When reacting, temperature, pressure, and time are all key factors. Temperature control needs to be accurate to achieve the best reaction effect, and the reaction should not be out of control due to sudden changes in temperature. The pressure should also be stable to prevent the container from being overwhelmed and causing accidents. The control of time should not be ignored. If it is too short, the reaction will not be complete, and if it is too long or the side effect will be caused.
In the operation room, the ventilation must be good to dissipate harmful gas. Operators must wear protective equipment, such as protective clothing, gloves, goggles, etc., to prevent their objects from coming into contact with the body and causing injury to the body.
When storing, it is appropriate to store in a cool, dry and ventilated place, away from fire and heat sources. When placed separately from oxidants, reducing agents, alkalis, etc., it must not be mixed to avoid danger.
When handling, handle it with care to avoid damage to its container. If there is a leak, quickly cut off the fire source, evacuate personnel to a safe place, and strictly limit access. Emergency responders use protective equipment to clean leaks according to regulations. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be embanketed and then dealt with.
In short, the safe production and operation of 3,5-difluoro-4-bromonitrobenzene are related to everyone's safety and smooth production, and must not be taken lightly.
Application Area
Today, there is a product called 3,5-difluoro-4-bromonitrobenzene, which is widely used in the field of chemical industry. It can be a key raw material in the synthesis of medicine. Doctors who want to make special drugs often rely on this to start the synthesis sequence. After delicate steps, it can help the active ingredients to form, or it can be an antibacterial agent, or it can be a medicine for treating other diseases.
In the context of material research and development, it also has its uses. It can be integrated into new materials and give materials unique properties. For example, the preparation of special polymer materials can increase its stability, weather resistance, and is suitable for special environments.
In the field of electronic chemistry, it can be the foundation for building electronic components. To help form special electronic materials, optimize the conductivity, insulation and other properties of components, and contribute to the advancement of electronic technology. This is the field of application of 3,5-difluoro-4-bromonitrobenzene, which is indispensable for today's scientific and technological development.
Research & Development
Yu Taste is dedicated to the research of 3,5-difluoro-4-bromo-nitrobenzene. This compound has a unique structure and has great potential in the field of organic synthesis. At the beginning, exploring its synthesis path encountered many obstacles. The choice of raw materials and the control of reaction conditions all need to be carefully considered.
After repeated tests, the proportion of reactants was adjusted to optimize the reaction temperature and duration. Finally, a feasible method was obtained, and this product could be prepared in a higher yield. However, it was not satisfied with this, and then its properties were studied to observe its stability in different solvents and environments.
After considering its application and expanding, after many attempts, it was found that it has unique advantages in the preparation of new drug intermediates. This research achievement paves the way for its future development, which is expected to shine brightly in the field of medicine and promote the progress of the industry.
Toxicity Research
Yu Xiangyan "3,5 - Difluoro - 4 - Brocamerrobenzene" This substance is toxic for a long time. Looking at its structure, fluorine, bromine, and nitro groups are concentrated in the benzene ring, which are all groups with strong reactivity and toxicity.
Fluorine, although the atom is small, is extremely electronegative, easy to bond with other substances, and the bond energy is strong, difficult to decompose in the body, and it is chaotic to accumulate in the biochemical order. Bromine is also active, or causes protein and nucleic acid denaturation. Nitro has strong oxidative properties, which disturb cell metabolism and damage organ function.
From an experimental perspective, animals exposed to this substance have no Chinese fur, tired diet, and organ lesions. Or the liver is swollen and the color is different from usual; or the kidney function is declining, and the filth is difficult to discharge. It can be known that its percutaneous, oral, and respiratory entry into the body is very harmful. Those who study this thing must be cautious and well-protected, so as not to let poison invade the body, and the legacy is endless.
Future Prospects
I tried to study 3,5-difluoro-4-bromo-nitrobenzene, observe its properties, and think about the unfinished path. This material is very different, and it is quite promising in the field of organic synthesis. Although it is used today, it is still limited, but looking forward to the future, it may open up new paths and solve problems.
The industry of organic synthesis often depends on various raw materials, and 3,5-difluoro-4-bromo-nitrobenzene may be the key. It can be used to create new drugs, cure various diseases; it can also help to develop new materials and improve their properties.
I am convinced that with time and advanced scientific research, I will be able to make the best of my ability. In the preparation of new drugs, it can become a prescription for special effects; in the research of new materials, it can create extraordinary things. This is the future that can be awaited, and it is also the direction for our researchers to strive forward.
Where to Buy 3,5-Difluoro-4-Bromonitrobenzene in China?
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Frequently Asked Questions

As a leading 3,5-Difluoro-4-Bromonitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,5-difluoro-4-bromonitrobenzene?
3,2,5-Diene-4-carbonylphenylalanine, an important organic compound, is widely used in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique chemical structure and active groups, it can participate in various chemical reactions and help synthesize many biologically active drug molecules. By modifying and modifying its structure, chemists can develop new drugs for specific diseases, such as anti-tumor and anti-viral drugs. Taking the development of an anti-tumor drug as an example, researchers cleverly used 3,2,5-diene-4-carbonyl phenylalanine as a starting material to successfully construct a molecular structure that specifically binds to tumor cell targets through multi-step reactions. After clinical trials, the drug exhibited significant inhibitory effects on specific tumor cells.
In the field of materials science, it also has good performance. Because of its specific chemical properties, it can be used to prepare high-performance polymer materials. In polymerization reactions, it participates in the reaction as a monomer, giving the material special properties, such as good mechanical properties, thermal stability or optical properties. For example, in the preparation of high-performance engineering plastics, the introduction of this compound can greatly improve the strength and toughness of plastics, making it widely used in aerospace, automobile manufacturing and other fields that require strict material properties.
In the field of biochemical research, 3,2,5-diene-4-carbonylphenylalanine can mimic the function of some natural amino acids in living organisms. Because its structure is similar to natural amino acids, it can participate in the protein synthesis process, thereby changing the structure and function of proteins. Scientists can use this to deeply explore the relationship between protein structure and function, providing key clues to reveal the mystery of life processes. When studying the mechanism of protein action in a signal transduction pathway, by incorporating the compound into the protein, the key check point of protein-ligand binding and the specific process of signal transmission were successfully analyzed.
What are the synthesis methods of 3,5-difluoro-4-bromonitrobenzene?
The synthesis method of 3,5-diene-4-hydroxycarbonyl naphthalene can be obtained in several ways.
First, it can be initiated by the derivative of naphthalene. First, take the naphthalene, introduce the alkenyl group and hydroxycarbonyl group under specific reaction conditions. In a suitable solvent, use a specific catalyst to make the naphthalene react with the reagent containing alkenyl groups and hydroxycarbonyl groups. If an ether solvent is selected, a metal salt is used as the catalyst, and the temperature is controlled within a certain range, this reaction may be achieved. This reaction process needs to be carefully regulated. Because the active site of the naphthalene ring is specific, if you don't pay attention, side reactions will occur.
Second, it can be converted from more complex cyclic compounds. Take a cyclic compound with a similar structure and modify the structure one by one through several steps to achieve the target product. First, the substituents of the cyclic compound are subjected to specific conversion reactions, or nucleophilic substitution, electrophilic substitution and other means. Then, through cyclization, the desired naphthalene ring structure is constructed, and alkenyl and hydroxycarbonyl are introduced in suitable steps. This approach requires a deep understanding of the reaction properties of the cyclic compound, and the conditions of each step of the reaction need to be precisely controlled.
Third, it can also be synthesized by gradual condensation using small molecule compounds as raw materials. First, the small molecules are condensed in a certain order to form an intermediate with a certain carbon chain structure. In the condensation process, various organic reactions are skillfully used, such as esterification, aldehyde-ketone condensation, etc. Then, through cyclization and functional group conversion reactions, naphthalene rings are constructed and 3,5-diene-4-hydroxycarbonyl structures are introduced. Although there are many steps in this method, each step of the reaction is relatively controllable, and the raw materials and reaction conditions can be flexibly adjusted according to the requirements of the target product.
All synthesis methods have their own advantages and disadvantages. In practical application, careful choices should be made according to many factors such as the availability of raw materials, the difficulty of reaction, yield and purity requirements.
What are the physical properties of 3,5-difluoro-4-bromonitrobenzene?
The physical properties of 3,5-diene-4-hydroxyquinoline compounds are as follows:
Most of these compounds are crystalline solids, which is due to the existence of various intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., which promote the orderly arrangement of molecules and form a regular lattice structure. Different substituents will significantly affect the melting point. If the substituent can enhance the intermolecular force, the melting point will increase; conversely, if the substituent weakens the intermolecular force, the melting point will decrease. For example, the presence of strong polar hydroxyl groups and other substituents can enhance the intermolecular hydrogen bond and increase the melting point.
In terms of solubility, due to the polar hydroxyl groups in the molecule and the quinoline ring with a certain conjugate structure, in polar organic solvents such as ethanol and acetone, it has good solubility by virtue of the hydrogen bond and dipole-dipole interaction between the molecule and the solvent; in non-polar solvents such as n-hexane, due to the weak interaction between the molecule and the solvent, the solubility is poor.
The density is closely related to the molecular structure. The molecular structure of such compounds is relatively compact, and the atomic arrangement is relatively close, so that their density is usually higher than that of water. This is because the type and number of atoms in the molecule determine the relative molecular mass, and the spatial structure increases the mass per unit volume.
In addition, 3,5-diene-4-hydroxyquinoline compounds have certain optical properties. Due to the conjugated system of the quinoline ring, an absorption spectrum will be generated under light irradiation of a specific wavelength. The electron cloud of the conjugated system transitions under light excitation, thus showing unique absorption characteristics. Some of these compounds may also have fluorescent properties. After being excited by light, electrons transition from the ground state to the excited state, and when they return to the ground state, they release energy in the form of light radiation to generate fluorescence. These optical properties have potential applications in the fields of analysis and detection, biological imaging, etc.
What is the market price of 3,5-difluoro-4-bromonitrobenzene?
The price of this well in the market, 3% 2C5-diene-4-cyanofuran-based materials, because of its special use and difficulty in making, the price is not constant, and it mostly depends on supply and demand and craftsmanship.
Looking at the cities, if there are many people who need this product, and there are few people who supply it, the price will increase. And its production is also, or it needs rare materials, or it depends on exquisite methods, all of which increase its value. If the craftsmanship is refined, the materials used are easy to obtain, and the supply is available, the price may be flat, or even drop.
Also, its price is also related to the quality of quality. Those who are of high quality can respond to high standards, and those who are of good use in various professions will have a high price; those who are of poor quality will only be suitable for regular needs, and the price will be low.
From this perspective, if you want to know the market price of 3% 2C5-diene-4-cyanofuran-based products, when you carefully consider the supply and demand, the cleverness of the craftsmanship, and the quality of the products, you cannot generalize. The market price changes rapidly, and only by looking carefully can you get a rough idea.
What are the precautions for storing and transporting 3,5-difluoro-4-bromonitrobenzene?
3% 2C5-diene-4-hydroxybenzyl requires attention to many matters during storage and transportation. The properties of this substance are quite special, and when storing, it is necessary to choose a dry, cool and well-ventilated place. Because it is extremely sensitive to temperature and humidity, it is easy to deteriorate if the temperature is too high, and if the humidity is too high, it may cause deliquescence, which in turn affects its quality and performance. Therefore, the temperature of the storage environment should be maintained in a specific range, and the humidity should be strictly controlled within a reasonable range.
Furthermore, this substance should be separated from oxidizing and reducing substances. Because of its active chemical properties, if it coexists with the above substances, it is very likely that violent chemical reactions will occur, resulting in serious accidents such as fires and explosions. The storage area should also be equipped with corresponding fire protection and emergency treatment equipment for emergencies.
During transportation, the packaging must be tight and tight. Use high-quality packaging materials to prevent leakage during transportation. At the same time, the means of transportation need to be kept clean to avoid mixing with other impurities to contaminate the substance. Transport personnel should be familiar with its characteristics and emergency treatment methods, and the transportation route planning should also be thorough to avoid densely populated areas and environmentally sensitive areas as much as possible to prevent serious consequences in the event of accidents.
The transportation process also needs to be implemented in accordance with relevant regulations and standards to ensure compliance. Once there is an abnormal situation such as leakage during transportation, emergency plans should be activated immediately and effective measures should be taken to deal with it to prevent the harm from further expanding. In this way, the safety of 3% 2C5-diene-4-hydroxybenzyl can be guaranteed during storage and transportation, and its good quality can be maintained.