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3,5-Difluoro-1-Methoxybenzene

3,5-Difluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code

172678

Chemical Formula C7H6F2O
Molar Mass 144.12 g/mol
Appearance Colorless liquid
Boiling Point 154 - 155 °C
Density 1.176 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 46 °C
Refractive Index 1.455 - 1.457

As an accredited 3,5-Difluoro-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL bottle of 3,5 - difluoro - 1 - methoxybenzene, well - sealed for chemical storage.
Storage 3,5 - difluoro - 1 - methoxybenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames to prevent ignition. Keep it in a tightly closed container to avoid vapor leakage. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Use a storage location with secondary containment in case of container failure.
Shipping 3,5 - difluoro - 1 - methoxybenzene is shipped in sealed, corrosion - resistant containers. It's transported under regulated conditions, ensuring proper handling to prevent spills, as it's a chemical with specific safety requirements during transit.
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3,5-Difluoro-1-Methoxybenzene 3,5-Difluoro-1-Methoxybenzene
General Information
Historical Development
Wenfu 3,5-difluoro-1-methoxybenzene is widely used in various fields of chemical industry today. Back to its origin, in the past, chemical sages dedicated themselves to studying, so that this product appeared before the world.
At the beginning, its properties were not deeply explored, and the preparation method was cumbersome and inefficient. However, over the years, the public has been unremitting, and they have repeatedly improved on the preparation process. The complicated and difficult methods of the past have gradually been replaced by simple and efficient techniques.
Looking at its development, from the initial ignorance to today's emergence in many fields such as medicine and materials, it all depends on the chemists of all dynasties, who worked hard and studied day and night. Therefore, the use of 3,5-difluoro-1-methoxybenzene is expanding day by day, adding to today's scientific and technological progress, and its future should be broader.
Product Overview
Today there is a substance called 3,5-difluoro-1-methoxybenzene. It is an organic compound with a unique structure. In this substance, fluorine atoms and methoxy groups are cleverly connected, and they are arranged in an orderly manner on the benzene ring.
Looking at its physical properties, at room temperature, or in the form of a colorless liquid, it has a certain volatility. Although its smell is not pungent, it also has a unique smell. In organic solvents, it has good solubility and can be soluble with a variety of common solvents.
In terms of use, it plays an important role in the field of organic synthesis. It is often a key intermediate, helping to prepare many complex organic compounds. Due to the special properties of fluorine atoms, the product can be endowed with unique chemical activity and stability; the existence of methoxy groups also affects the process of the reaction and the characteristics of the product. Therefore, 3,5-difluoro-1-methoxylbenzene is of great value in many industries such as chemical industry and medicine.
Physical & Chemical Properties
There is a substance named 3,5-difluoro-1-methoxybenzene. Its physical state is at room temperature or a colorless and transparent liquid, which has a specific fragrance. In terms of its physical properties, the boiling point is of great concern, about a certain temperature range, which is related to its state transition in different environments. And its density is moderate, which is related to the distribution when mixed with other substances.
When it comes to chemical properties, this compound has certain reactivity. It contains fluorine atoms, and fluorine has strong electronegativity, resulting in a specific distribution of molecular electron clouds, which gives it a unique performance in reactions such as nucleophilic substitution. The presence of methoxy groups also affects its chemical behavior, or can participate in the electronic effects on aromatic rings, making the compound exhibit unique characteristics in various chemical reaction paths, and may have potential application value in the field of organic synthesis.
Technical Specifications & Labeling
3,5-Difluoro-1-methoxylbenzene Technical Specification and Identification (Product Parameters)
If you want to make 3,5-difluoro-1-methoxylbenzene, the first technical specification. The synthesis method requires precise steps. First take an appropriate amount of fluorine-containing raw materials, mix them with methoxyl-containing reagents in a specific ratio, and react catalytically at a suitable temperature and pressure to combine the two. The reaction process, when closely monitoring the temperature and reaction time, is related to the purity and yield of the product.
As for the label (product parameters), 3,5-difluoro-1-methoxybenzene, the appearance is often colorless and transparent liquid, with a special smell. Its purity needs to be above 99%, and the impurity content is extremely low. Physical parameters such as boiling point and melting point also need to be accurately determined to meet product specifications. In this way, only qualified 3,5-difluoro-1-methoxybenzene products can meet the needs of all parties.
Preparation Method
The preparation method of 3,5-difluoro-1-methoxybenzene is related to raw materials and production process, reaction steps and catalytic mechanism.
To make this product, prepare raw materials, including fluoroaromatic hydrocarbons and methoxylation reagents. Take an appropriate amount of fluoroaromatic hydrocarbons and place them in a special reactor. The kettle needs to be corrosion-resistant and temperature-controlled. Then, according to the precise ratio, slowly add the methoxylation reagent, paying attention to the ratio of the two, which is related to the purity and yield of the product.
The reaction steps are rigorous, first heat up to a specific range, about one hundred and twenty to one hundred and fifty degrees Celsius, and at the same time apply stirring to fully blend the materials and accelerate the reaction. At this stage, the catalytic mechanism is involved, and specific catalysts, such as metal salts, are added to reduce the activation energy of the reaction and promote the efficient progress of the reaction.
After the reaction is completed, the separation and purification technique is used, and the pure 3,5-difluoro-1-methoxybenzene is obtained by extraction and distillation. This preparation method involves interlocking each step, and the raw materials, reaction, catalysis and purification are all heavy to produce high-quality products.
Chemical Reactions & Modifications
In today's world, in the field of chemistry, it is the task of all scholars to study the properties and changes of substances in order to improve. Today, there is 3,5-difluoro-1-methoxybenzene, and our generation of chemistry students should study its wonders.
Its chemical reaction is related to various changes in synthesis and decomposition. In the past, if there are any unfinished aspects, the reaction conditions, such as temperature, pressure, and the nature of catalysts, may be optimized to promote the smooth reaction and increase its yield. And the purity of its products, there is also room for improvement.
As for its chemical modification, we can introduce other groups and change its structure in order to obtain new substances with specific properties. Or it can be used in materials and medicine for different purposes. We should use our diligence to explore its principles and seek new frontiers in chemistry, so that this material can be used to the best of our ability and contribute to the progress of the world.
Synonyms & Product Names
There is a recent thing called 3,5-difluoro-1-methoxybenzene. The synonymous name of this thing is also investigated by us. Although its names are different, they actually refer to this chemical thing.
In the industry, or those who call it another name are all synonymous. Looking at the market, there are also many names for its products. However, no matter what the name is, it refers to this 3,5-difluoro-1-methoxybenzene.
We are researchers of chemistry, and we study the properties and functions of this thing in depth. Many synonymous names help us to understand the records and studies of this thing in various parties. And the name of the product is also related to its distribution and application. Therefore, it is of great benefit to study its synonymous name and commodity name in our generation to explore this 3,5-difluoro-1-methoxybenzene.
Safety & Operational Standards
Specifications for safety and operation of 3,5-difluoro-1-methoxybenzene
Fu 3,5-difluoro-1-methoxybenzene is a common substance in chemical research. If you want to use it well, you must understand its safety and operation specifications.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Because it has certain chemical activity, it is dangerous to be exposed to heat or open flames, so the storage place must be carefully guarded.
When using it, you must strictly follow the operating procedures. The operator is in front of suitable protective equipment, such as protective clothing, gloves and goggles, to protect himself. Avoid direct contact with the skin and eyes. If you accidentally touch it, you should immediately rinse it with a lot of water and seek medical treatment in time.
In the experimental operation room, ventilation equipment must ensure normal operation, so that the concentration of the substance in the air is maintained within the safe limit. And do not eat, drink or smoke in the operation area to prevent harm caused by ingestion or inhalation.
If there is a leak during operation, do not panic. First, you should quickly evacuate irrelevant personnel and isolate the leakage area. Depending on the size of the leak, take corresponding measures. Small leaks can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection. If there are large leaks, you need to build a dike or dig a pit to contain them, and recycle them with professional equipment or transfer them to a safe place for disposal.
Furthermore, the transportation of this substance must also strictly abide by relevant regulations. Use compliant transportation tools to ensure stable packaging and prevent damage and leakage during transportation. Transportation personnel should be familiar with emergency treatment methods for emergencies.
In short, in the research and application of 3,5-difluoro-1-methoxybenzene, safety and standardized operation are of paramount importance. Only in this way can we ensure the smooth research, the well-being of personnel and the environment.
Application Area
Today there is a thing called 3,5-difluoro-1-methoxybenzene, which is widely used. In the field of medicine, it is often the basis for the creation of new drugs. From this, all kinds of special drugs can be made to heal serious diseases. In the field of agrochemical, it can assist in the research of anti-insect and anti-disease agents and keep crops fertile. And in the field of materials, it is also indispensable, which can make materials have specific properties, such as better stability and conductivity. Therefore, 3,5-difluoro-1-methoxybenzene has shown extraordinary performance in various application fields, and it is actually the key to chemical research in this world.
Research & Development
Today, there is a product named 3,5-difluoro-1-methoxybenzene. As a chemical researcher, I have been very attentive to the research and development of this product.
Preliminary investigation of its structure, fluorine and methoxy, especially the key, affecting its properties. After various experiments, its physicochemical properties are known. It shows unique activity in the reaction, can react with many substances, form new compounds, and has potential applications.
We also explore the method of its preparation, striving for high efficiency and environmental protection. Optimize the process, reduce waste production. Expand its use in medicine and materials to emit light and heat. This is the wish of our researchers to make unremitting efforts to promote its development and make it available to the world.
Toxicity Research
In recent years, those who have studied chemical substances have focused on the toxicity study of 3,5-Difluoro-1-Methoxybenzene. The use of this substance in industry and scientific research is becoming more and more widespread, but its impact on the health of the people and the surrounding nature is not yet clear.
We have measured it by various methods to observe its effect on the microbial body, the plant and the moving body. The process of experimentation is to abide by regulations and strive for accuracy. At the beginning, we took the microbial body as a test to observe its growth and reproduction. Then we tested it with the plant, and observed the changes in its germination, foliage, flowering and fruiting. Test it again with the moving body, and examine the differences in its behavior and physiological functions.
After months of study, we have obtained preliminary results. When this thing is high and concentrated, it inhibits the growth of the microbial body and hinders its reproduction speed. When it is planted, it may cause the leaves to yellow and the flowers to fall, reducing its vitality. When it is in motion, it also has the appearance of perverse behavior and physiological violation. However, the degree of toxicity and the long-term harm to human health and the natural environment need to be further explored and studied carefully before we can be sure and think that the world will use this thing as a lesson.
Future Prospects
I have tried to study this substance in 3,5 - Difluoro - 1 - Methoxybenzene. Viewing its properties, it has specific qualities and can be used in various fields.
Although the research has been successful today, the future development still has a great potential. In industry, it may be possible to optimize the process, increase its yield, reduce its cost, and make it widely used. Medicine, or according to its nature, explore new ways of medicine, and add new paths to cure diseases.
Furthermore, the field of materials, or can be used to develop new materials, has better properties. I believe that with time and careful study, 3,5 - Difluoro - 1 - Methoxybenzene will be able to shine in the future, contributing to the progress of the world, developing endless possibilities, and achieving unfinished business.
Where to Buy 3,5-Difluoro-1-Methoxybenzene in China?
As a trusted 3,5-Difluoro-1-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3,5-Difluoro-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,5-difluoro-1-methoxybenzene?
3,5-Diene-1-methoxybenzene, an organic compound with a wide range of uses.
In the field of organic synthesis, it is often used as a key intermediate. Through a series of chemical reactions, compounds with different structures and functions can be derived. For example, by addition reactions with specific reagents, more complex carbon skeletons can be constructed, laying the foundation for the synthesis of drug molecules with specific biological activities. Taking the development of a new anti-cancer drug as an example, 3,5-diene-1-methoxybenzene is linked to nitrogen-containing heterocyclic compounds through multi-step reactions, and finally synthesized into lead compounds with inhibitory activity of cancer cell proliferation.
In the field of materials science, it also has important value. Due to its special molecular structure, it can participate in the polymerization reaction of polymer materials. For example, copolymerization with ethylene monomers can endow polymer materials with unique optical and electrical properties. In this way, the prepared materials can be applied to organic Light Emitting Diode (OLED), solar cells and other fields to improve the photoelectric conversion efficiency and stability of materials.
It also plays an important role in the fragrance industry. Due to its unique smell, it can be used as a fragrance ingredient to prepare perfumes, flavors and other products. When properly prepared, it can add a fresh and unique aroma to the product and enhance the olfactory experience of the product. For example, in a high-end fragrance formulation, trace amounts of 3,5-diene-1-methoxybenzene can be cleverly combined with other fragrances to create a rich, long-lasting and attractive fragrance.
What are the physical properties of 3,5-difluoro-1-methoxybenzene?
3,5-Diene-1-methoxybenzene is a type of organic compound. Its physical properties are as follows:
Appearance: Under normal conditions, it is mostly a colorless to light yellow liquid. This color and state are easier to observe in general laboratory environments or industrial scenes.
Odor: has a special aromatic odor, which is highly recognizable. Those who are familiar with the odor characteristics of organic compounds will know its uniqueness at a glance.
Melting point: about -48 ° C. This melting point indicates that when below this temperature, 3,5-diene-1-methoxybenzene will change from liquid to solid. In practice, if a low temperature environment is involved, it is necessary to pay attention to its physical state changes to prevent it from affecting the experiment or production process.
Boiling point: Roughly in the range of 195-197 ° C. When the temperature rises to the boiling point, the compound will transform from liquid to gaseous state. This boiling point data is of great significance for separation and purification operations by means of distillation.
Density: About 0.97g/cm ³. This density characteristic determines its relative position when mixed with other liquids. For example, when mixed with water, it will float on the water surface because its density is less than that of water.
Solubility: Soluble in common organic solvents such as ethanol, ether, acetone, etc. This solubility property is crucial in organic synthesis and helps to select the appropriate reaction solvent so that the reaction can proceed smoothly. However, it is insoluble in water, and this property can be operated by the difference between the aqueous and organic phases during the separation and purification of compounds.
In addition, the physical properties of 3,5-diene-1-methoxybenzene, such as vapor pressure and refractive index, also have their specific values. These properties play an indispensable role in fine chemical analysis and related chemical production processes, providing an important basis for accurately controlling the properties and behaviors of compounds.
What are the chemical properties of 3,5-difluoro-1-methoxybenzene?
3,5-Diene-1-methoxybenzene, which has the properties of alkenes and ethers. Its alkenyl bond can exhibit the opposite of electrophilic addition. In the case of hydrogen halide, halogen and other reagents, halogen atoms are added to the alkenyl bond carbon to form halogenated hydrocarbons. If it comes into contact with bromine water, the reddish-brown color of bromine fades, and it is due to the addition of the alkenyl bond and bromine to obtain dibromide.
Its methoxy group is a donator group, which has an activating effect on the benzene ring, which increases the density of the electron cloud of the benzene ring and the para-position, and is more vulnerable to the attack of electrophilic reagents. Taking the nitrification reverse as an example, nitro groups can be introduced into the o-
Ether bonds also have characteristics. In a strong acid environment, protonation can occur, followed by bond breaking to form halogenated hydrocarbons and alcohols. For example, co-heating with hydrohalic acids, ether bond cracking, halogenated methanes and phenolic derivatives.
This compound can participate in a variety of organic synthesis due to its alkenyl bond and methoxy group. Organic molecules with complex structures are prepared, which have potential applications in medicine, materials and other fields. The study of its chemical properties helps to clarify the reaction mechanism and provides an important foundation for the creation and optimization of organic synthesis methods.
What is the production method of 3,5-difluoro-1-methoxybenzene?
3,5-Diene-1-methoxybenzene is an important organic compound and has a wide range of uses in many fields. Although the method of its preparation is not detailed in "Tiangong Kaiwu", it can be roughly prepared by referring to ancient methods and modern organic synthesis.
To obtain 3,5-diene-1-methoxybenzene, a compound containing a benzene ring can be selected as the starting material. If benzene is used as the group, a methoxy group can be introduced into the benzene ring by substitution reaction. The method of methoxy group introduction can make phenol and halomethane react under basic conditions. The oxygen anion of the phenolic hydroxyl group attacks the carbon atom of the halomethane, and the halogen ion leaves to form methoxybenzene.
After obtaining methoxybenzene, try to introduce the diene structure at a specific position in the benzene ring. This step can be achieved by electrophilic substitution reactions such as the Fu-gram reaction. With a suitable olefin halide as a reagent, under the catalysis of Lewis acid, the olefin halide generates a carbon cation, which acts as an electrophilic reagent to attack the benzene ring of methoxybenzene. Because the methoxy group is an ortho and para-site group, the reaction mainly obtains ortho and para-site substitution products. By controlling the reaction conditions and the ratio of reagents, the substituent can mainly fall at the 3,5 position to form 3,5-diene-1-methoxybenzene. During the preparation process of
, many factors affect the formation of the product. The temperature needs to be precisely controlled. If the temperature is too low, the reaction rate is slow and time-consuming; if the temperature is too high, side reactions are easy to occur, resulting in poor product purity. The proportion of reagents is also critical. If there is too much of a reagent, it may cause side reactions such as multiple substitution. In addition, the choice and dosage of catalysts also affect the reaction efficiency and selectivity. Different catalysts have different activities and selectivity. Reasonable selection and control of their dosage can make the reaction proceed efficiently in the expected direction to obtain high purity 3,5-diene-1-methoxybenzene.
What are the precautions for storing and transporting 3,5-difluoro-1-methoxybenzene?
3% 2C5-diene-1-methoxybenzene is also an organic compound. When storing and transporting, be sure to pay attention to many matters.
First words storage. This compound should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can be avoided from reacting due to excessive temperature and causing property variation; dry place, it can be prevented from hydrolysis by moisture, which will damage the purity; well ventilated, it can avoid the accumulation of harmful gases and maintain its chemical stability. And it should be kept away from fire and heat sources, which can easily cause the compound to catch fire or explode, endangering safety. At the same time, it must be stored separately from oxidizing agents, acids, alkalis, etc., because the compound and their substances may react violently and cause danger.
Secondary transportation. During transportation, the packaging must be firm and tight to prevent leakage. The packaging materials selected should have good corrosion resistance and sealing to ensure that the compound is not damaged during transportation bumps. Transportation vehicles should also be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment for emergencies. When driving, drive according to the specified route, avoid densely populated areas and traffic arteries, and reduce the possible harm caused by accidents. And transportation personnel should be familiar with the characteristics of the compound and emergency treatment methods. In case of emergencies, they can respond quickly and correctly to ensure transportation safety.