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3,5-Dibromo-1-(Trifluoromethoxy)Benzene

3,5-Dibromo-1-(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    266099

    Chemical Formula C7H3Br2F3O
    Molar Mass 329.901 g/mol
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Approximately 195 - 200 °C
    Density Around 2.0 - 2.2 g/cm³
    Solubility Soluble in organic solvents like dichloromethane, chloroform, less soluble in water
    Vapor Pressure Low vapor pressure at room temperature
    Flash Point Relatively high, > 100 °C
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 3,5-Dibromo-1-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3,5 - dibromo - 1 - (trifluoromethoxy)benzene in a sealed chemical - grade bottle.
    Storage 3,5 - dibromo - 1 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like glass or some plastics. This helps prevent evaporation, degradation, and potential chemical reactions.
    Shipping 3,5 - dibromo - 1 - (trifluoromethoxy)benzene is shipped in well - sealed, corrosion - resistant containers. Special handling precautions are taken due to its chemical nature, ensuring safe transport following all relevant regulations.
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    3,5-Dibromo-1-(Trifluoromethoxy)Benzene 3,5-Dibromo-1-(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    3,5-Dibromo-1- (trifluoromethoxy) benzene is also an organic chemical. The beginning of its research was covered in the past year. At that time, the wise men explored the field of organic synthesis diligently, hoping to obtain new quality and expand the frontier of chemistry.
    At the beginning, the synthesis method was still simple, the obtained product was impure, and the yield was quite low. However, the public was not discouraged, and they studied it for many years. With the passage of time, chemical technology has advanced day by day, and new techniques have emerged one after another.
    In recent years, the method of synthesizing this compound has become more and more refined, the yield has increased, and the purity has also been excellent. Its application in medicine, materials and other fields has gradually become more and more important in the world. Looking at its historical evolution, it is actually the condensation of the wisdom and hard work of chemists, and it is also a witness to the development of chemistry.
    Product Overview
    3,5-Dibromo-1- (trifluoromethoxy) benzene is a key raw material for organic synthesis. Its color is pure and pure, and its properties are stable. Viewed, it is often a colorless to pale yellow transparent liquid, and can also be crystalline under specific conditions.
    This product has unique chemical properties, and its bromine atom and trifluoromethoxy give it active reactivity. In the field of organic synthesis, various functional groups can be introduced through various reactions such as nucleophilic substitution and coupling to build complex organic molecular structures.
    Because of its special structure, it has important uses in medicine, pesticides and materials science. In pharmaceutical research and development, it may be used as a lead compound to help create new drugs; in the field of pesticides, it is expected to derive high-efficiency and low-toxicity pesticide varieties; in materials science, it may provide a key building block for the synthesis of new functional materials.
    Preparation of this product requires fine control of the reaction conditions to achieve the goal of high purity and high yield. Its quality is related to the effectiveness of subsequent applications.
    Physical & Chemical Properties
    There is a substance named 3,5-dibromo-1- (trifluoromethoxy) benzene. The physical and chemical properties of this substance are related to many studies. Its appearance may be in a specific form, or in a crystalline state, color or purity, or with a slight luster. At room temperature, its stability can be observed, and it may change under specific conditions.
    In terms of its chemical properties, it has a unique reactivity due to its bromine and trifluoromethoxy groups. Bromine atoms are active and can participate in substitution and other reactions; the existence of trifluoromethoxy groups gives it special chemical properties, or affects its reaction path and products with other substances. Its solubility varies in different solvents. It may be soluble in some organic solvents, but not in water. This property is also closely related to the molecular structure. These physicochemical properties lay the foundation for its application in chemical, pharmaceutical and other fields, and are also the key to our researchers' in-depth investigation.
    Technical Specifications & Labeling
    There is a product today, named 3,5-dibromo-1 - (trifluoromethoxy) benzene. In this product, process specifications and identification (product parameters) are the key.
    In terms of process specifications, the synthesis method needs to be rigorous. The choice of raw materials must be pure, the proportion is accurate, and the temperature and time of the reaction are fixed. If the starting materials are mixed, the temperature is controlled in a certain range. After several times, the reaction is completed, and the post-treatment needs to be fine. The steps of extraction and distillation are interlocked to obtain a good product.
    As for the identification (product parameters), the appearance should be a specific color state, the purity must reach a high standard, and the impurity content is minimal. Molecular weight, melting point, boiling point and other data need to be clear and accurate to prove the quality. In this way, it meets the requirements of the process specifications and identification (product parameters) of this product and can be used in all required places.
    Preparation Method
    The raw materials and production process, reaction steps and catalytic mechanism of 3,5-dibromo-1 - (trifluoromethoxy) benzene are the key.
    To prepare this product, prepare the raw materials first. Based on specific aromatic hydrocarbons, supplemented by bromide and reagents containing trifluoromethoxy. The aromatic hydrocarbons need to be pure, the bromide activity should be high, and the reagents containing trifluoromethoxy need to be accurately proportioned.
    In the production process, in a suitable reactor, control the temperature, pressure and stirring rate. First put the aromatic hydrocarbons and bromide, and add the reagents containing trifluoromethoxy dropwise in a specific order. At the beginning of the reaction, the temperature is raised to a moderate level, and the activation is urged. After that, it is stabilized at a certain temperature to maintain a uniform reaction speed.
    The reaction steps are rigorous. The first is bromination, so that the bromine atom occupies a specific position of the aromatic hydrocarbon, and then trifluoromethoxy is introduced to form the target structure. After each step of the reaction, the separation and purification technique is applied to remove impurities and improve the purity.
    The catalytic mechanism is promoted by a dedicated catalyst. The catalyst is selected with high activity and selectivity, which reduces the reaction energy barrier and increases the reaction rate and yield. During the whole reaction process, various parameters are carefully observed, timely fine-tuning is made to ensure the smooth production, and high-quality 3,5-dibromo-1 - (trifluorometh
    Chemical Reactions & Modifications
    Wenfu 3,5 -dibromo-1 - (trifluoromethoxy) benzene, in the field of chemical synthesis, its reaction and modification are quite important to our generation.
    Looking at its reaction, there are many complicated methods in the past. To obtain this compound, the selection of raw materials and the control of conditions need to be fine. Bromide is often used to interact with reagents containing trifluoromethoxy, but during the reaction, side reactions occur frequently, and the yield is not ideal.
    As for modification, it is aimed at increasing its properties. Or introduce other groups into its structure to change its physicochemical properties, and hope to be used in special materials and pharmaceutical synthesis. If a hydrophilic group is introduced, its solubility can be changed, making it easier to apply in biological systems.
    Today, we are following the foundation of our predecessors, innovating methods and optimizing conditions, hoping to improve the synthesis efficiency and performance of this compound, so as to meet the needs of various fields and contribute to the progress of chemistry.
    Synonyms & Product Names
    Today there is a thing called 3,5-dibromo-1- (trifluoromethoxy) benzene. Although the names are different, there are also many synonymous names. This thing is unique in the field of chemistry.
    In various chemical books and studies, its synonymous names are called either according to its structural characteristics or according to its use nature. In order to sell it widely, merchants also give names to other products, which are eye-catching.
    This 3,5-dibromo-1- (trifluoromethoxy) benzene is either used in the preparation of special materials or is the key to organic synthesis. Although the names vary, they all refer to the same thing. According to its characteristics, chemists study it with precision, explore its mysteries, and seek its benefits in science and industry.
    Safety & Operational Standards
    Specifications for the safety and operation of 3,5-dibromo-1- (trifluoromethoxy) benzene
    Fu 3,5-dibromo-1- (trifluoromethoxy) benzene is an important substance in chemical research. During its experimental operation and research process, safety regulations and operating standards are of paramount importance.
    First word safety. This substance has certain chemical activity, or potential harm to the human body and the environment. Therefore, when exposed, protective measures are indispensable. Experimenters wear protective gloves and goggles in front of suitable protective clothing to prevent the substance from touching the skin and eyes and causing injury. And the operation should be carried out in a well-ventilated experimental site, or with the help of a fume hood, so that the volatile gas can be discharged in time, so as not to inhale the body and damage the respiratory and nervous systems.
    Furthermore, storage should also be paid attention to. It should be placed in a cool, dry and ventilated place, away from fire and heat sources, to prevent it from changing its chemical properties due to changes in temperature and humidity and causing safety accidents. At the same time, it should be placed separately from substances of different properties such as oxidation and reduction to avoid mutual reaction.
    Operating specifications. When taking it, use a clean and accurate instrument and take it according to the required amount of the experiment, not more or less. The measurement process must be careful to prevent substances from spilling out. If it is accidentally spilled, it should be cleaned up immediately in accordance with relevant procedures to avoid polluting the environment.
    During the reaction operation, the reaction conditions, such as temperature, pressure, reaction time, etc., should be strictly controlled. Precise regulation can make the reaction proceed in the expected direction, and can reduce the occurrence of side reactions, and ensure the safety and accuracy of the experiment. After the reaction is completed, the treatment of the product should also be in compliance, or properly stored, or the waste should be disposed of according to environmental protection requirements.
    In short, in the research and application of 3,5-dibromo-1- (trifluoromethoxy) benzene, safety and operation standards are fundamental, and the experimenter must strictly abide by them in order to achieve the research purpose and ensure their own safety and environmental safety.
    Application Area
    "3,5-Dibromo-1- (trifluoromethoxy) benzene application field"
    There are chemical substances 3,5-dibromo-1- (trifluoromethoxy) benzene, and its application field is quite extensive. In the field of pharmaceutical chemistry, it can be used as a key intermediate to help synthesize specific drugs to cure various diseases, or it can be of great help to the drug research of difficult and complicated diseases. In the field of materials science, it can contribute to the creation of new functional materials, or make materials with unique electrical and optical properties, used in high-end electronic devices, optical instruments, etc. In the field of organic synthesis, with its unique chemical structure, it can participate in a variety of organic reactions, expand the variety of organic compounds, and inject new vitality into the development of organic synthetic chemistry, driving the field forward.
    Research & Development
    3,5-Dibromo-1- (trifluoromethoxy) benzene is being studied today. Its properties are related to research and development, and are of paramount importance. At the beginning, the method of its synthesis was explored, and after many attempts, it was a delicate way. With a certain method, the yield gradually increases and the quality is also excellent.
    In the field of application, its performance is widely observed. Tried in various reactions, it can be seen that it can promote the efficient implementation of certain kinds of reactions, and it has great potential. Also look at its impact on the environment, and strive to use it harmlessly and well.
    Although there is progress now, it is not stopped. In the future, deep research, expand its use, improve its quality, and develop its strength in the chemical industry.
    Toxicity Research
    Today, there is a substance called 3,5-dibromo-1- (trifluoromethoxy) benzene. I am a chemical researcher, so I studied the toxicity of this substance. Examining its properties carefully, this substance has a unique structure and contains bromine and trifluoromethoxy groups. After various experiments, observe its effect in the body. White mice were tested and fed food containing this substance. Not long after, the white mice gradually showed a different state, slow movement, and reduced diet. The organs, liver and kidneys showed signs of damage. It can be seen that this 3,5-dibromo-1- (trifluoromethoxy) benzene is toxic and harmful to the health of organisms. Studying the toxicity of this substance can provide evidence for those who use it or avoid its harm in the future, ensure the well-being of all beings, and add a guarantee for the safety of chemical industries.
    Future Prospects
    I have been researching 3,5-dibromo-1 - (trifluoromethoxy) benzene for a long time. Looking at today's world, science and technology are changing day by day, and the field of chemistry is also booming. In this product, I see its future has a broad outlook.
    It may become a key agent in the creation of medicine. With its unique structure, it may be able to help doctors make special drugs to treat serious diseases and save patients from water and fire. In the process of material research and development, it is also expected to emerge. Or as the basis of new materials, endow materials with specificity, and use them in aerospace, electronics and other fields to promote their leap.
    Although there may be thorns in the road ahead, I firmly believe that with time and joint efforts to study it, I will be able to do my best to add a lot of light to the well-being of mankind, and bloom brightly on the unfinished path.
    Where to Buy 3,5-Dibromo-1-(Trifluoromethoxy)Benzene in China?
    As a trusted 3,5-Dibromo-1-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Dibromo-1-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-dibromo-1- (trifluoromethoxy) benzene?
    3,5-Dibromo-1 - (triethoxyformyl) benzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Through a series of carefully designed chemical reactions, it can be skillfully converted into a wide range of other organic compounds. For example, it can react with specific nucleophiles to achieve precise construction and modification of molecular structures, thus laying the foundation for the creation of organic materials with unique properties and functions.
    In the field of pharmaceutical research and development, it also shows potential important value. Due to its unique chemical structure, it is very likely to become a starting material for the synthesis of new drug molecules. Through structural modification and modification, it is expected to develop highly effective therapeutic drugs for specific diseases and contribute to human health and well-being.
    In the field of materials science, 3,5-dibromo-1- (triethoxyformyl) benzene can be used to prepare functional polymer materials. With its special chemical activity, it can participate in polymer polymerization reactions, endowing materials with special properties such as fluorescence and conductivity, thus showing broad application prospects in frontier fields such as optoelectronic materials and sensors.
    What are the physical properties of 3,5-dibromo-1- (trifluoromethoxy) benzene?
    3,5-Dibromo-1- (triethoxyformyl) benzene is an organic compound, and its physical properties are as follows:
    From the perspective of this compound, it is often in the state of white to light yellow crystalline powder. Under sunlight, it can be seen that its texture is fine and its luster is slightly soft.
    When it comes to the melting point, it is about a specific temperature range. This characteristic makes it melt into a liquid state at the corresponding temperature during the heating process, providing key parameters for its application in specific processes.
    As for solubility, it can exhibit certain solubility in common organic solvents such as ethanol and ether. In ethanol, with moderate stirring, it can be seen that it is partially dissolved to form a slightly cloudy dispersion system; in ether, the dissolution state is better, and a relatively clear solution can be formed. This solubility is conducive to its use as a reactant or intermediate in organic synthesis reactions, and uniform dispersion and reaction can be achieved with the help of suitable solvents.
    Furthermore, its density is also an important physical property. Although the exact value needs to be accurately determined, the approximate range can reflect its relative relationship with the density of common substances, which is related to the distribution state in the mixed system.
    In addition, the chemical properties of this compound are relatively stable at room temperature and pressure. In case of special conditions, such as high temperature, strong oxidizing agent, etc., or specific chemical reactions, although this is not the category of physical properties, it affects its performance in practical applications together with physical properties. In conclusion, these physical properties are of great significance for understanding the properties and applications of 3,5-dibromo-1 - (triethoxyformyl) benzene.
    What are the chemical properties of 3,5-dibromo-1- (trifluoromethoxy) benzene?
    3,5-Dibromo-1 - (triethoxy methoxy) benzene, its chemical properties are quite unique.
    In this compound, the presence of bromine atoms gives it a certain reactivity. Bromine is an active halogen element and can participate in nucleophilic substitution reactions in many chemical reactions. Due to its high electronegativity, the carbon-bromine bond has a certain polarity, which makes the bond easier to break. Foreign nucleophiles can attack the carbon atoms connected to it, resulting in substitution reactions. For example, it reacts with nucleophiles such as sodium oxide and thiol salts to generate corresponding substitution products.
    Furthermore, the 1- (triethoxy methoxy) part also affects its chemical properties. Triethoxy methoxy is a relatively large substituent, and its steric hindrance effect cannot be ignored. This steric hindrance can affect the reactivity and selectivity of molecules. In some reactions, the presence of large steric hindrance groups can hinder the reactants from approaching the reaction center and reduce the reaction rate; in other reactions, it can guide the reaction to selectively occur in parts with small steric hindrance. In addition, the ethoxy part of the triethoxy methoxy group has unshared electron pairs on the oxygen atom, which can form coordination bonds with some metal ions. This property may have certain applications in catalytic reactions or complexation reactions.
    At the same time, the conjugation system of the phenyl ring also has an important impact on the properties of this compound. The conjugated π electron cloud of the benzene ring imparts certain stability to the molecule, and can influence the substituents on the benzene ring. When the electrophilic substitution reaction occurs, the substituent localization effect of 3,5-dibromo-1 - (triethoxymethoxy) benzene is significant. Bromine atoms are ortho-and para-site locators. Although the electron cloud density of the benzene ring is reduced and the benzene ring is passivated, it can guide the electrophilic reagent to attack its ortho and para-sites; while triethoxymethoxy group is the power supply group, which can increase the electron cloud density of the benzene ring, activate the benzene ring, and also guide the electrophilic reagent to attack its ortho and para-sites. Combining the localization effects of the two, the main products of the electrophilic substitution reaction can be predicted according to
    What are the synthesis methods of 3,5-dibromo-1- (trifluoromethoxy) benzene?
    The synthesis of 3,5-dibromo-1- (triethoxymethoxy) benzene is a key issue in the field of organic synthesis. Several common synthesis paths are described in detail below:
    First, benzene is used as the starting material, and bromine atoms are introduced through a bromination reaction. In this step, liquid bromine can be used to react with benzene under the catalysis of iron or iron tribromide to generate bromobenzene. Because bromine is an ortho-para-site group, a mixture of o-bromobenzene and p-bromobenzene will be produced, which needs to be separated by fractionation or column chromatography to obtain p-bromobenzene. Subsequently, p-bromobenzene and triethoxy methane underwent a substitution reaction under the action of a specific catalyst, and triethoxy methoxy was introduced into the para-position of the benzene ring, resulting in the final target product 3,5-dibromo-1- (triethoxy methoxy) benzene. Although this path is easy to obtain raw materials, the bromination reaction selectivity is poor, and the separation process is more complicated.
    Second, phenol can be used as the starting material first, and phenol can be reacted with bromine water. Because the phenolic hydroxyl group is a strong activating group, bromine atoms can be directly introduced at the 3,5 positions of the benzene ring to generate 3,5-dibromophenol. Then, 3,5-dibromophenol and triethoxy methyl halide undergo nucleophilic substitution reaction in a suitable organic solvent under basic conditions, such as the presence of potassium carbonate. The oxygen atom of the phenolic hydroxyl group attacks the carbon atom of the triethoxy methyl halide, and the halogen ion leaves to generate 3,5-dibromo-1- (triethoxy methoxy) benzene. The advantage of this method is that the bromination step has good selectivity, and 3,5-dibromo substitution products can be directly obtained. However, the phenol needs to be pretreated and the reaction conditions need to be precisely controlled.
    Third, the Suzuki coupling reaction strategy can also be used. First, borate containing triethoxy methoxy was prepared, and benzene derivatives containing bromine atoms were prepared at the same time. The coupling reaction of the two occurred under palladium catalyst, ligand and basic conditions. This method has mild conditions and high selectivity, and can effectively construct carbon-carbon bonds. It is widely used in the synthesis of complex benzene derivatives. However, palladium catalysts are expensive and have high reaction costs. Post-treatment also requires certain skills to remove catalyst residues.
    All these synthesis methods have advantages and disadvantages. In practical application, the most suitable synthesis path needs to be carefully selected according to many factors such as raw material availability, cost considerations, target product purity requirements and reaction conditions.
    What are the precautions for storing and transporting 3,5-dibromo-1- (trifluoromethoxy) benzene?
    In the storage and transportation of 3,5-dibromo-1 - (triethoxyformyl) benzene, the following matters should be paid attention to.
    In terms of storage, the first environmental choice should be made. It should be placed in a cool and ventilated place, as it is sensitive to temperature and air circulation. Excessive temperature can easily cause changes in the properties of substances, and good ventilation can prevent the accumulation of harmful gases. The warehouse must be kept away from fires and heat sources, both of which may cause dangerous reactions.
    At the same time, it should be strictly separated from oxidants, acids, bases and other substances. Because of its active chemical properties, contact with these substances, or react violently, endangering safety. The storage area should be equipped with suitable materials for containing leaks to prevent accidental leaks and respond in time to reduce hazards.
    As for transportation, the packaging must be tight and firm. According to relevant regulations, appropriate packaging materials and methods should be used to ensure that the packaging will not be damaged due to bumps and collisions during transportation and cause leaks. During transportation, vehicles should be equipped with corresponding varieties and quantities of fire protection equipment and leakage emergency treatment equipment. Transportation personnel need to be professionally trained and familiar with the characteristics of the transported items and emergency treatment methods. Driving routes should avoid densely populated areas and busy traffic sections to reduce the risk of accidents. If there is an emergency such as a leak during transportation, emergency measures should be taken immediately and relevant departments should be reported in a timely manner. Only in this way can the safety of 3,5-dibromo-1- (triethoxyformyl) benzene be ensured during storage and transportation.