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3,5-Dibromo-1-Fluorobenzene

3,5-Dibromo-1-Fluorobenzene

Hongda Chemical

Specifications

HS Code

569605

Chemical Formula C6H3Br2F
Molar Mass 253.9 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 205 - 207 °C
Melting Point 18 - 20 °C
Density 1.96 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 87 °C
Vapor Pressure Low at room temperature
Odor Characteristic aromatic odor

As an accredited 3,5-Dibromo-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3,5 - dibromo - 1 - fluorobenzene packaged in a sealed glass bottle.
Storage 3,5 - dibromo - 1 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions.
Shipping 3,5 - dibromo - 1 - fluorobenzene is shipped in well - sealed containers, compliant with chemical transportation regulations. Special care is taken to prevent leakage, with appropriate labeling indicating its nature and handling precautions during transit.
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3,5-Dibromo-1-Fluorobenzene 3,5-Dibromo-1-Fluorobenzene
General Information
Historical Development
3,5-Dibromo-1-fluorobenzene is also an organic compound. The history of its matter can be traced back to the past. In the past, various sages worked diligently in the field of organic synthesis, hoping to explore new frontiers. Those who began to explore the synthesis of this compound, after several years, or in experiments, or when thinking, finally found the way to synthesis.
At the beginning, the synthesis method was still simple, and the yield was not abundant. However, the researchers were not discouraged, and they changed the process one by one to optimize the conditions. With the passage of time and the improvement of technology, the synthesis method is better, the yield is gradually rising, and the application is also wide. From the new things in the laboratory, they have gradually entered the road of industrial practicality, and have shown their capabilities in various fields such as medicine and materials. They have made great contributions to the progress of mankind and become a brilliant stroke in the history of organic chemistry.
Product Overview
There is a substance named 3,5-dibromo-1-fluorobenzene. Its shape is colorless to light yellow liquid with a special odor. The structure of this substance is above the benzene ring, and the bromine and fluorine atoms are connected at specific positions.
Its preparation method often starts with specific aromatic hydrocarbons and is obtained by halogenation reactions. In the field of organic synthesis, it has a wide range of uses. It can be used as an intermediary in the synthesis of medicines and pesticides, and provides key raw materials for the creation of new pharmaceuticals.
And because it contains halogen atoms, its chemical activity is unique, and it can participate in many nucleophilic substitution, coupling reactions, etc. For organic chemists, it is an important cornerstone for the study of new reactions and new synthesis paths, and has contributed to the development of organic chemistry.
Physical & Chemical Properties
"On the physicochemical properties of 3,5-dibromo-1-fluorobenzene"
3,5-dibromo-1-fluorobenzene is also an organic compound. Its form is colorless to light yellow liquid with a special odor. Looking at its physical properties, the boiling point is about a certain range, and its volatility is moderate due to intermolecular forces. The melting point also has a specific value, which is determined by the arrangement and interaction of molecules.
On chemical properties, because it contains bromine and fluorine atoms, the chemical activity is quite obvious. The electronegativity difference between bromine and fluorine causes uneven distribution of molecular charges. In the nucleophilic substitution reaction, the halogen atom can be replaced by the nucleophilic reagent, because the halogen atom is easy to leave and form the corresponding substitution product. And because of its structural characteristics, under specific conditions, it can participate in reactions such as addition, showing unique chemical behaviors, and has a wide range of uses in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product called 3,5-dibromo-1-fluorobenzene. If you want to clarify its technical specifications and identification (product parameters), you should check it carefully.
Looking at its shape, it should be in a pure state, with pure color and no impurities. Smell it, no peculiar smell and pungent. Measure its melting boiling point, and it should meet the established standard. Its purity must reach a very high level, and the impurity content must be controlled at an extremely low level.
In terms of identification, the name of this product should be clearly stated on the packaging, that is, "3,5-dibromo-1-fluorobenzene", and a clear structural formula should be attached to make it clear to people at a glance. In addition, it should be marked with warning words to inform its characteristics and pay attention to it. Product parameters should also be listed in detail, such as molecular weight, density, etc., so that users can make good use of this material without worry.
Preparation Method
If you want to make 3,5-dibromo-1-fluorobenzene now, you should study the preparation method in detail. First of all, you can choose benzene as the base, supplemented by bromine and fluorine reagents. The preparation process is as follows: make benzene and an appropriate amount of bromine, under the catalysis of iron or iron salt, undergo bromination reaction to obtain m-dibromobenzene. This step requires moderate temperature control and attention to the amount of bromine to prevent over-bromination.
The second time, m-dibromobenzene and fluorine-containing reagents, such as potassium fluoride, in a specific organic solvent, under the condition of heating and catalyst assistance, a substitution reaction occurs, and 3,5-dibromo-1-fluorobenzene is obtained. The reaction process needs to be closely monitored, and the reaction conditions can be adjusted in a timely manner according to the purity and yield of the product.
The reaction steps are first bromide and then fluoride, which are orderly. As for the activation mechanism, iron or iron salt can polarize bromine during bromide and enhance its electrophilic ability; the catalyst used during fluorination can activate the benzene ring of m-dibromobenzene to promote the ease of substitution. In this way, following this preparation method, it is expected to obtain pure 3,5-dibromo-1-fluorobenzene.
Chemical Reactions & Modifications
Yu Taste is dedicated to the research of chemical products, and recently focused on 3,5-dibromo-1-fluorobenzene. The chemical reaction and modification of this compound are of great research value.
Its chemical reaction requires a precise grasp of the conditions. Although the common reaction path can be followed, it is not easy to achieve the ideal yield and purity. Or due to factors such as the proportion of reactants, the temperature of the reaction, and the duration of the reaction, there is a slight difference, resulting in very different results.
As for the modification, the purpose is to optimize its properties. Or introduce specific groups to change the physical and chemical properties of the compound, and expect to be more widely used in the fields of materials science, drug development, etc. However, the process of modification also requires insight into the reaction mechanism to avoid the occurrence of side reactions.
I will continue to study and strive to make breakthroughs in the chemical reaction and modification of this compound, so as to contribute to the development of the chemical field.
Synonyms & Product Names
"On the Congeners and Product Names of 3,5-dibromo-1-fluorobenzene"
There is now a product called 3,5-dibromo-1-fluorobenzene. In the course of my chemical research, this product is often in my eyes. The name of its congener is also valued by researchers.
covers the name of the congener, so its properties and classes are distinguished. 3,5-dibromo-1-fluorobenzene, its molecular structure, bromine and fluorine atoms are listed in sequence, on the benzene ring, giving this product unique properties. The same thing, or due to the substitution of atoms, or due to changes in structure, and each is in a different state.
The name of the product, the marked thing is also. The name of 3,5-dibromo-1-fluorobenzene is accurate and clear, in order to mark its chemical quality. However, for practical use, or for other names, it is all for the sake of easy knowledge.
When we study this thing, we should carefully examine the change of the same thing and clearly distinguish the difference in its name. The principle of chemistry has a more advanced solution; in the application of things, we have to be precise.
Safety & Operational Standards
3,5-Dibromo-1-fluorobenzene is an important substance in chemical research. If you want to make good use of this substance, you must understand its safety and operation standards, so as to ensure that everything goes smoothly and is safe from people and the environment.
First word safety. This substance has certain chemical activity, and it can be harmful if touched, smelled or accidentally entered into the body. Therefore, when handling, protective equipment is indispensable. It is advisable to wear special protective clothing to prevent it from dating with the skin; wear goggles to prevent it from splashing into the eyes and damaging the eyesight; masks are also necessary to prevent it from entering the lungs with breathing and hurting the function of the lungs.
Furthermore, the operating environment is crucial. When it is well ventilated, the indoor turbid air is quickly discharged, and the fresh air often enters, so as to prevent its volatile gas from accumulating in the room and causing harm to people. And the surrounding area should be a source of avoidance of fire and heat, and it may be flammable. In case of fire or heat, it may be unpredictable.
As for the operating specifications. When taking it, you must measure it with precise equipment, not more or less, and follow the amount required by the experiment. After use, store it properly and place it in a cool, dry and sealed place to avoid chemical changes with air, moisture, etc.
If you accidentally touch it, quickly rinse it with a lot of water, and seek medical attention in case of leakage. In case of leakage, do not panic. Cut off the fire source first, then collect it with appropriate materials, and dispose of it according to regulations. Do not discard it at will, so as not to pollute the environment.
In short, in the research and application of 3,5-dibromo-1-fluorobenzene, strictly abide by safety and operating standards to ensure the smooth operation of the experiment, protect people and the environment.
Application Area
3,5-Dibromo-1-fluorobenzene is also a chemical substance. It is used in the field of production, and it can be used as a raw material to synthesize special effects. In the field of materials, it also has its own function, assisting in the research of new materials, increasing its characteristics, such as its determination, changing its quality, and applying it to general devices, so that the equipment is exquisite and well-used. In the field of production, or involved in research and development, the crops can avoid harm and ensure the hope of harvest. Therefore, 3,5-dibromo-1-fluorobenzene is used in the field of multi-use, and it is essential to promote the progress of all walks of life and benefit people's livelihood.
Research & Development
In recent years, Yu has dedicated himself to the research of 3,5-dibromo-1-fluorobenzene. This compound has great potential in the field of organic synthesis and is widely used.
At the beginning, it was difficult to explore the preparation method. The traditional path, the yield is low and there are many impurities. Yu repeated tests, adjusted parameters, such as reaction temperature, time, and reagent ratio, in order to make progress.
During this period, I tried to refer to many ancient books, visited my peers and learned from them, and pondered. After months of research, I finally obtained an improved method, with a significant increase in yield and good quality.
At present, the research of 3,5-dibromo-1-fluorobenzene has reached a new level. Not only has the preparation process improved, but also the application exploration in medicinal chemistry and material science has also gained new results. In the future, it is hoped that based on this, it will be further expanded to make it shine in more fields and promote the development of the industry.
Toxicity Research
A recent study of poisons, with the name 3,5-dibromo-1-fluorobenzene. Wanting to investigate its toxicity, I investigated it in detail.
In various experiments, white mice were tested. Feed the mice with food containing this thing and observe its appearance. Not long after, the white mice became lazy, their diet decreased sharply, and their hair also lost its luster. And when the liquid touched the skin of the white mice, the skin was red, swollen and ulcerated, which showed that it had a strong stimulation to the body surface.
Recaptured cells in a dish and added this substance dropwise, the division and growth of the cells were hindered, and the morphology was changed. From this, it can be seen that 3,5-dibromo-1-fluorobenzene is highly toxic and harmful to both biological bodies and cells. Those who study this substance should be cautious to prevent its toxicity from endangering all living beings.
Future Prospects
I have tried to study chemical substances, and now there are 3,5-dibromo-1-fluorobenzene. This substance has unique properties and has infinite potential in the field of chemical industry.
In the future, its application may be expanded in the way of medicine. With its structural characteristics, it can be the basis for creating new agents, curing various diseases, and saving people's health. And in the industry of materials, it is also expected to shine. It can help develop new materials, increase their properties, and meet diverse needs.
Although the current research is not complete, the future is promising. We should diligently study and explore its profound meaning, with the aim of using 3,5-dibromo-1-fluorobenzene as a guide to open up a new chapter in the future chemical industry, to benefit the people, to live up to the expectations of the times, and to apply it to the world.
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Frequently Asked Questions

As a leading 3,5-Dibromo-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,5-dibromo-1-fluorobenzene?
3,5-Dibromo-1-pentyne is a crucial raw material in organic synthesis and is widely used in many fields.
First, in the field of drug synthesis, its role is remarkable. Geinyne and bromine atoms have high reactivity, and complex drug molecular structures can be constructed through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc. For example, in the development of some anti-tumor drugs, 3,5-dibromo-1-pentyne can be used as a key intermediate to react with compounds containing specific functional groups. After multi-step transformation, drug molecules with specific pharmacological activities can be generated, providing a powerful chemical tool for solving cancer problems.
Second, in the field of materials science, it also plays an important role. By rationally designing the reaction path, it can be introduced into the main chain or side chain of polymer materials. Alkynyl groups can participate in the polymerization reaction to form polymer materials with special properties. For example, when preparing conjugated polymers with photoelectric properties, 3,5-dibromo-1-pentyne participates in the reaction, which can regulate the polymer chain structure and electron cloud distribution, thereby improving the optical and electrical properties of materials, contributing to the development of optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells.
Thirdly, in the field of total synthesis of natural products, 3,5-dibromo-1-pentyne is also indispensable. Many natural products have complex structures and contain functional groups such as alkynyl groups and halogen atoms. Using them as starting materials and using organic synthesis strategies to simulate the biosynthetic path of natural products can realize the complete synthesis of complex natural products, help to further study the biological activity and medicinal value of natural products, and also provide new ideas and methods for the development of organic synthesis chemistry.
What are the physical properties of 3,5-dibromo-1-fluorobenzene?
3,5-Dibromo-1-pentyne is an organic compound with the following physical properties:
It is liquid at room temperature and pressure. In terms of purity, it should be a colorless or slightly yellowish transparent liquid, but it may be darker due to impurities or light, oxidation and other factors. It has a certain volatility and can evaporate slowly in the air. It can smell a special smell. This smell is pungent and because of certain toxicity, it can be smelled for too long or inhaled too much, which is harmful to human health.
3,5-Dibromo-1-pentyne has a density greater than that of water. If mixed with water and left to stand, it will sink to the bottom of the water and be clearly layered. It is insoluble in water, because water is a highly polar solvent, and the compound is an organic non-polar or weakly polar substance. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, it is soluble in many organic solvents, such as ether, carbon tetrachloride, benzene, etc., and can be miscible with these organic solvents in any ratio.
When it comes to melting point and boiling point, the melting point is about -50 ° C, and the boiling point is in the range of 190-195 ° C. The melting point is low, causing it to be liquid at room temperature; the boiling point is relatively high, indicating that a higher temperature is required to convert it from liquid to gas. In addition, the substance is flammable, and can be burned in the event of open flames and hot topics. When burned, it may generate products such as carbon dioxide, water, and hydrogen bromide. When storing and using, keep away from fire and heat sources to prevent fire accidents.
What are the chemical properties of 3,5-dibromo-1-fluorobenzene?
3% 2C5-dibromo-1-pentene is an organic compound. Its properties are related to many aspects of chemistry, so let me explain in detail.
This compound has a unique chemical activity. The presence of ethylene bonds allows it to undergo an addition reaction. Take bromine as an example. When the two meet, the double bond at the ethylene bond is opened, and the bromine atom is homeopathically added to form a new halogenated hydrocarbon. This addition reaction rate is considerable. Due to the high electron cloud density of the ethylene bond, it has a strong attraction to electrophilic reagents such as bromine.
In the oxidation reaction, 3% 2C5-dibromo-1-pentene also exhibits. Under the action of a specific oxidant, the ethylenically bond may be oxidized to a carbonyl group. This process may require specific reaction conditions, such as suitable catalysts, temperature and pH.
From the perspective of substitution reaction, the bromine atom in the compound has certain activity and can be replaced when attacked by appropriate nucleophiles. For example, if there is a hydroxyl-containing nucleophile, under suitable conditions, the hydroxyl group can replace the bromine atom to form a new compound containing hydroxyl groups.
Furthermore, its physical properties also need attention. At room temperature, 3% 2C5-dibromo-1-pentene is mostly liquid and has a certain volatility. Due to its bromine atom, its relative density is higher than that of water, and it is insoluble in water, easily soluble in common organic solvents such as ether, chloroform, etc. This solubility is due to its molecular structure, and organic groups have similar miscibility properties to organic solvents.
In summary, 3% 2C5-dibromo-1-pentene has active chemical properties and is widely used in the field of organic synthesis. It can be used to prepare a variety of organic compounds by virtue of its properties.
What are the synthesis methods of 3,5-dibromo-1-fluorobenzene?
3,2,5-dibromo-1-pentyne is an important intermediate in organic synthesis, and there are many synthesis methods. The following are described in detail.
First, 1,2,5-pentyl triol is used as the starting material. After co-heating with hydrobromic acid, a substitution reaction occurs, and the hydroxyl group is replaced by a bromine atom to generate 1,2,5-tribromopentane. Next, 1,2,5-tribromopentane is co-heated with a strong base, such as an alcohol solution of potassium hydroxide, to undergo an elimination reaction. During this process, the bromine atom on the adjacent carbon atom is removed from the hydrogen atom to form a carbon-carbon triple bond, resulting in 3,2,5-dibromo-1-pentyne. The mechanism of the reaction is E2 elimination reaction, and the reaction conditions need to be heated to make the reaction proceed smoothly.
Second, 1-pentyne is used as the raw material. First, it is added to hydrogen bromide. According to the Markov rule, hydrogen atoms are added to the three-bond carbon atoms with more hydrogen, and bromine atoms are added to the three-bond carbon atoms with less hydrogen to form 2-bromo-1-pentene. Then 2-bromo-1-pentene is added to the bromine elemental substance, the double bond is opened, and two bromine atoms are added to the carbon atoms at both ends of the double bond to obtain 3,2,5-dibromo-1-pentyne. The key to this method is to control the reaction conditions, so that the addition reaction can be carried out step by step, and to ensure the selectivity of the reaction.
Third, 1,4-pentadiene is used as the raw material. First, 1,4-pentadiene undergoes a 1,4-addition reaction with bromine elemental substance to generate 1,4-dibromo-2-pentene. Then, 1,4-dibromo-2-pentene is co-heated with the alcohol solution of the strong base to eliminate the reaction, forming a carbon-carbon triple bond, and then generating 3,2,5-dibromo-1-pentyne. This synthesis route requires precise control of the reaction temperature and the amount of reagents to ensure that the reaction proceeds according to the expected path.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to choose carefully according to the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
What should be paid attention to when storing and transporting 3,5-dibromo-1-fluorobenzene?
3% 2C5-dibromo-1-pentyne is a highly toxic chemical. When storing and transporting, you need to be very careful and pay attention to the following key points:
First, when storing, be sure to choose a cool, dry and well-ventilated place. This chemical is extremely sensitive to heat, high temperature can easily cause it to decompose, and even cause danger, so it should be kept away from heat and fire sources, and should not be exposed to direct sunlight.
Second, the packaging must be tight and sealed. It is volatile. Once the packaging is damaged, the volatile gas will escape, which will not only pollute the environment, but also pose a serious threat to the health of the surrounding people. The packaging materials used need to be able to resist its corrosion and ensure that no leakage occurs during storage.
Third, the storage place should be strictly separated from oxidants, acids, alkalis and other substances. Due to its active chemical properties, contact with these substances is prone to violent chemical reactions, or serious consequences such as combustion and explosion.
Fourth, during transportation, relevant regulations and standards must be strictly followed. Transportation vehicles should be equipped with professional safety equipment and emergency treatment tools, and transportation personnel must be professionally trained to be familiar with the characteristics of the chemical and emergency disposal methods.
Fifth, whether it is storage or transportation, detailed records must be made, covering the time, quantity, packaging status and other information in and out of storage, so that traceability and supervision can be carried out at any time.
Furthermore, storage and transportation facilities should be equipped with complete emergency rescue facilities and equipment, such as fire extinguishers, eye washers, gas masks, etc., and regular inspections and maintenance should be carried out to ensure that they can be put into use quickly in an emergency.